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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TVPWFPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLKS
LYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPM
YTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQY
CLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLD

The query sequence (length=309) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5fgj:A 428 309 0.9450 0.6822 0.9450 0.0 4anp:A, 5den:A, 5den:B, 5den:C, 5den:D, 1dmw:A, 5fgj:B, 5fgj:C, 5fgj:D, 6hpo:A, 6hyc:D, 6hyc:C, 6hyc:B, 1j8t:A, 1j8u:A, 1kw0:A, 1lrm:A, 1mmk:A, 1mmt:A, 6n1k:A, 6n1k:B, 6n1k:C, 6n1k:D, 1pah:A, 2pah:A, 2pah:B, 3pah:A, 4pah:A, 5pah:A, 6pah:A, 1phz:A, 2phm:A, 1tdw:A, 1tg2:A
2 4v06:A 349 307 0.6602 0.5845 0.6645 2.74e-154 4v06:B, 7wiy:B, 7wiy:C, 7wiy:D, 7wiy:A
3 3e2t:A 307 307 0.6408 0.6450 0.6450 5.82e-152 8cji:A, 8cjj:A, 8cjk:A, 8cjl:A, 8cjm:A, 8cjn:A, 8cjo:A, 3hf6:A, 3hf8:A, 3hfb:A, 5j6d:A, 5l01:A, 1mlw:A, 7zif:A, 7zig:A, 7zih:A, 7zii:A, 7zij:A, 7zik:A, 7zik:B
4 5jk5:A 400 308 0.6311 0.4875 0.6331 1.78e-150 5jk5:B, 5jk6:A, 5jk6:B, 5jk8:A, 5jk8:B
5 6zvp:D 458 308 0.6408 0.4323 0.6429 4.59e-150 7a2g:A, 7a2g:B, 7a2g:C, 7a2g:D, 7pim:B, 7pim:A, 7pim:D, 7pim:F, 1toh:A, 2toh:A, 2xsn:A, 2xsn:B, 2xsn:C, 2xsn:D, 6zn2:A, 6zn2:C, 6zn2:E, 6zn2:G, 6zvp:A, 6zvp:B, 6zvp:C, 6zzu:B, 6zzu:A, 6zzu:C, 6zzu:D
6 5tpg:A 271 290 0.5728 0.6531 0.6103 3.67e-125
7 5j6d:B 248 287 0.5307 0.6613 0.5714 1.08e-102
8 2v27:B 272 227 0.2460 0.2794 0.3348 1.23e-34 2v27:A
9 4etl:A 277 234 0.2524 0.2816 0.3333 2.27e-32 4esm:A, 4jpx:A, 4jpy:A, 1ltv:A, 1ltz:A, 4q3w:A, 4q3x:A, 4q3y:A, 4q3z:A, 3tcy:A, 3tk2:A, 3tk4:A
10 7vgm:A 571 237 0.2071 0.1121 0.2700 3.13e-22
11 7l6s:A 396 118 0.1133 0.0884 0.2966 1.00
12 6due:A 737 67 0.0647 0.0271 0.2985 3.9
13 7dve:A 498 63 0.0583 0.0361 0.2857 4.7
14 7esn:A 435 143 0.1100 0.0782 0.2378 4.9 7esk:A, 7esm:A, 8i4d:A, 7yqs:A
15 1mdx:A 366 58 0.0518 0.0437 0.2759 6.6 1mdo:A, 1mdz:A, 4oca:A
16 5hvf:A 372 147 0.1068 0.0887 0.2245 6.8
17 6b3p:A 209 60 0.0583 0.0861 0.3000 8.3 6b3p:B
18 3s5w:B 414 16 0.0324 0.0242 0.6250 9.9 3s5w:A, 3s61:A, 3s61:B
19 4p10:A 402 142 0.1100 0.0846 0.2394 9.9 3d66:A, 3d66:B, 3d66:C, 3d67:A, 3d67:B, 3d67:C, 3d68:A, 3d68:B, 3d68:C, 5hvg:A, 5hvg:C, 5hvh:A, 3lms:A, 7nee:A, 7neu:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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