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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TVFYTSIDIGSRYIKGLVLGKDQEWEALAFSSVKSRGLDEGEIKDAIAFKESVNTLLKELEEQLQKSSDFVISFSSVSFE
REDTVIERDFGEEKRSITLDILSEMQSEALEKLKENGKTPLHIFSKRYLLDDERIVFNPLDMKASKIAIEYTSIVVPLKV
YEMFYNFLQDTVKSPFQLKSSLVSTAEGVLTTPEKDRGVVVVNLGYNFTGLIAYKNGVPIKISYVPVGMKHVIKDVSAVL
DTSFEESERLIITHGNAVYNDLKEEEIQYRGLDGNTIKTTTAKKLSVIIHARLREIMSKSKKFFREVEAKIVEGIPGGVV
LTGGGAKIPRINELATEVFKSPVRTGCYANSDRPSIINADEVANDPSFAAAFGNVFA

The query sequence (length=377) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4a2b:A 386 384 1.0000 0.9767 0.9818 0.0 4a2a:A, 4a2a:B, 1e4g:T
2 7q6g:A 388 387 0.2228 0.2165 0.2171 8.31e-17 7q6d:A
3 7q6i:B 383 354 0.2175 0.2141 0.2316 2.12e-16 7q6f:A, 7q6f:B, 7q6i:A, 7q6i:C, 7q6i:E, 7q6i:F, 7q6i:G, 7q6i:H, 7q6i:I, 7q6i:J, 7q6i:K, 7q6i:L, 7q6i:M, 7q6i:N, 7q6i:O, 7q6i:P
4 3wt0:D 378 359 0.2175 0.2169 0.2284 1.36e-14 3wqt:A, 3wqt:C, 3wqt:D, 3wqu:A, 3wqu:B, 3wqu:C, 3wqu:D, 3wt0:A, 3wt0:B, 3wt0:C
5 3wqt:B 334 349 0.2069 0.2335 0.2235 2.20e-14
6 7q6i:D 362 353 0.2122 0.2210 0.2266 7.85e-14
7 4zm1:C 232 122 0.0875 0.1422 0.2705 1.2
8 3ctz:A 617 63 0.0557 0.0340 0.3333 2.5
9 8fkt:SY 378 90 0.0637 0.0635 0.2667 2.6 8fku:SY, 8fkv:SY, 8fkw:SY, 8fkx:SY, 8fky:SY
10 3qid:A 492 76 0.0477 0.0366 0.2368 3.6 3nai:A, 3nai:B, 3nai:C, 4nru:A, 4nru:B, 4nru:C, 4nru:D, 4nru:E, 4nru:F, 4o4r:A, 4o4r:B, 4o4r:C, 3qid:B, 3qid:C, 3sfg:A, 3sfg:B, 3sfg:C, 3sfu:A, 3sfu:B, 3sfu:C, 3upf:A, 3upf:B, 3upf:C, 3ur0:B, 3ur0:C
11 4gt2:A 371 49 0.0424 0.0431 0.3265 3.7 4gt2:B, 4gt2:E, 4gt2:G, 6gzw:A, 6gzw:B, 5map:A, 5map:B, 5mjh:A, 5mjh:B
12 3jc9:Ma 355 178 0.1141 0.1211 0.2416 4.2 3jc9:Mb, 3jc9:Mc, 3jc9:Md, 3jc9:Me, 3jc9:Mf, 3jc9:Mg, 3jc9:Mh, 3jc9:Mi, 3jc9:Mj, 3jc9:Mk, 3jc9:Ml
13 7kh2:D 415 64 0.0584 0.0530 0.3438 5.3 7kh2:A, 7kh2:B, 7kh2:C
14 7o0k:B 126 49 0.0531 0.1587 0.4082 6.0 2jn3:A, 2k62:A, 2lfo:A, 7o0k:A, 1tw4:A, 1tw4:B
15 1n2z:A 245 28 0.0318 0.0490 0.4286 6.5 5m29:A, 5m29:B, 5m2q:A, 5m2q:B, 5m34:A, 5m34:B, 5m3b:A, 5m3b:B, 1n2z:B, 1n4a:A, 1n4a:B
16 8a98:H 221 45 0.0477 0.0814 0.4000 6.5 8a3w:H, 6az3:H, 3jcs:H, 8ovj:H, 8rxh:LH, 8rxx:LH, 5t2a:M
17 7nqr:A 386 121 0.0796 0.0777 0.2479 8.2 7nqr:B, 7nqs:A, 7nqs:B, 7nqu:A, 7nqu:B, 7nqz:A, 7nqz:B, 7ooe:A, 7ooe:B, 7oog:A, 7oog:B, 7ooh:A, 7ooh:B, 7p31:A, 7p31:B, 6rzq:A, 6rzq:B, 6s02:A, 6s02:B
18 5tky:A 597 21 0.0292 0.0184 0.5238 9.9 5tky:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218