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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TTTYDYIVVGGGTSGLVVANRLSENPDVSVLLLEAGASVFNNPDVTNANGYGLAFGSAIDWQYQSINQSYAGGKQQVLRA
GKALGGTSTINGMAYTRAEDVQIDVWQKLGNEGWTWKDLLPYYLKSENLTAPTSSQVAAGAAYNPAVNGKEGPLKVGWSG
SLASGNLSVALNRTFQAAGVPWVEDVNGGKMRGFNIYPSTLDVDLNVREDAARAYYFPYDDRKNLHLLENTTANRLFWKN
GSAEEAIADGVEITSADGKVTRVHAKKEVIISAGALRSPLILELSGVGNPTILKKNNITPRVDLPTVGENLQDQFNNGMA
GEGYGVLAGASTVTYPSISDVFGNETDSIVASLRSQLSDYAAATVKVSNGHMKQEDLERLYQLQFDLIVKDKVPIAEILF
HPGGGNAVSSEFWGLLPFARGNIHISSNDPTAPAAINPNYFMFEWDGKSQAGIAKYIRKILRSAPLNKLIAKETKPGLSE
IPATAADEKWVEWLKANYRSNFHPVGTAAMMPRSIGGVVDNRLRVYGTSNVRVVDASVLPFQVCGHLVSTLYAVAERASD
LIKEDA

The query sequence (length=566) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4ynt:A 570 566 1.0000 0.9930 1.0000 0.0 7vkd:A, 7vkf:A, 7vzp:A, 7vzp:B, 7vzs:A, 7vzs:B, 4ynu:A
2 6xut:A 589 583 0.3852 0.3701 0.3739 7.97e-122 6xuu:A, 6xuv:A
3 1cf3:A 581 577 0.3640 0.3546 0.3570 2.03e-103 1gal:A, 8jpz:A, 8jpz:B, 5nit:A, 5niw:A, 3qvp:A, 3qvr:A
4 1gpe:B 587 572 0.3498 0.3373 0.3462 1.45e-100 1gpe:A
5 6ze7:B 586 613 0.3198 0.3089 0.2953 2.08e-64 7aa2:A, 7aa2:B, 6ze2:A, 6ze2:B, 6ze3:A, 6ze4:A, 6ze4:B, 6ze5:A, 6ze5:B, 6ze6:A, 6ze6:B, 6ze7:A
6 3fim:B 565 582 0.3004 0.3009 0.2921 7.85e-57 5oc1:A
7 6o9n:A 613 628 0.3216 0.2969 0.2898 6.89e-54 6o9n:B
8 4h7u:A 577 604 0.3428 0.3362 0.3212 3.26e-53
9 8il4:C 619 633 0.3198 0.2924 0.2859 1.85e-52 8il4:A, 8il4:B, 8il4:D
10 8bxl:B 590 603 0.2933 0.2814 0.2753 4.87e-47 8bxl:C, 8bxl:D, 8bxl:A, 8bxl:F, 8bxl:E
11 8il5:B 595 635 0.3074 0.2924 0.2740 1.48e-44
12 3q9t:A 577 606 0.2739 0.2686 0.2558 9.86e-43 3q9t:B, 3q9t:C, 5zu2:A, 5zu2:B, 5zu2:C, 5zu3:A, 5zu3:B, 5zu3:C
13 5ncc:A 578 590 0.3004 0.2941 0.2881 1.75e-42 7av4:AAA, 5ncc:B, 5ncc:C, 5ncc:D, 5ncc:E, 5ncc:F, 7r33:A, 7r33:B, 7r34:A, 7r34:B, 7r35:A, 7r35:B, 7r36:A, 7r36:B, 6yru:AAA, 6yrv:AAA, 6yrx:AAA, 6yrz:AAA, 6ys1:AAA, 6ys2:AAA, 6zh7:A, 6zh7:B
14 5hsa:A 662 667 0.2986 0.2553 0.2534 2.56e-42 5hsa:B, 5hsa:C, 5hsa:D, 5hsa:E, 5hsa:F, 5hsa:G, 5hsa:H, 5i68:A
15 3t37:A 509 554 0.2580 0.2868 0.2635 3.69e-39 4ha6:A
16 8b7s:A 458 568 0.2739 0.3384 0.2729 7.40e-37
17 4udq:A 525 586 0.2756 0.2971 0.2662 1.65e-35 6f97:A, 6f97:B, 4udp:A, 4udp:B, 4udq:B, 4udr:A, 4udr:B
18 4mjw:A 532 582 0.2898 0.3083 0.2818 2.94e-33 2jbv:A, 2jbv:B, 3ljp:A, 3ljp:B, 4mjw:B, 3nne:A, 3nne:B, 3nne:C, 3nne:D, 3nne:E, 3nne:F, 3nne:G, 3nne:H
19 6h3o:F 650 324 0.1820 0.1585 0.3179 1.73e-31 6h3g:A, 6h3g:B, 6h3g:C, 6h3g:F, 6h3g:D, 6h3g:E, 6h3g:G, 6h3g:H, 6h3o:A, 6h3o:B, 6h3o:C, 6h3o:D, 6h3o:E, 6h3o:G, 6h3o:H, 8il5:A
20 6h3o:F 650 89 0.0636 0.0554 0.4045 7.20e-14 6h3g:A, 6h3g:B, 6h3g:C, 6h3g:F, 6h3g:D, 6h3g:E, 6h3g:G, 6h3g:H, 6h3o:A, 6h3o:B, 6h3o:C, 6h3o:D, 6h3o:E, 6h3o:G, 6h3o:H, 8il5:A
21 6jby:A 521 555 0.2562 0.2783 0.2613 6.58e-14 7bwp:A, 7cgs:A, 5eb4:A, 5eb4:B, 5eb5:A, 5eb5:B, 8jm0:A, 8jm1:A, 8jm2:A, 8jm3:A, 8jm4:A, 8jm5:B, 8jm6:A, 8jm7:A, 8jm8:A, 6lqy:A, 6lr8:A
22 7yx4:A 650 360 0.1484 0.1292 0.2333 5.29e-13 7ptv:A, 7ptv:B, 7yx4:B, 7yx5:A
23 7yx4:A 650 49 0.0406 0.0354 0.4694 5.20e-04 7ptv:A, 7ptv:B, 7yx4:B, 7yx5:A
24 3gdn:A 521 560 0.2403 0.2610 0.2429 1.41e-12 3gdn:B, 3gdp:A, 3gdp:B, 1ju2:A, 1ju2:B
25 3red:A 521 563 0.2509 0.2726 0.2522 2.24e-12 3red:B, 3red:C, 3red:D, 3red:E, 3red:F, 3red:G, 3red:H, 3red:I, 3red:J, 3red:K, 3red:L
26 8orh:A 649 355 0.1484 0.1294 0.2366 2.97e-11 8orh:B, 8ors:A, 8ors:B, 7yx3:A, 7yx3:B, 4z24:A, 4z24:B, 4z25:A, 4z25:B, 4z25:C, 4z25:D, 4z25:E, 4z25:F, 4z25:G, 4z25:H, 4z25:I, 4z25:J, 4z25:K, 4z25:L, 4z26:A, 4z26:B, 4z26:C, 4z26:D, 4z26:E, 4z26:F, 4z26:G, 4z26:H
27 8orh:A 649 49 0.0406 0.0354 0.4694 0.004 8orh:B, 8ors:A, 8ors:B, 7yx3:A, 7yx3:B, 4z24:A, 4z24:B, 4z25:A, 4z25:B, 4z25:C, 4z25:D, 4z25:E, 4z25:F, 4z25:G, 4z25:H, 4z25:I, 4z25:J, 4z25:K, 4z25:L, 4z26:A, 4z26:B, 4z26:C, 4z26:D, 4z26:E, 4z26:F, 4z26:G, 4z26:H
28 1kdg:B 546 596 0.2420 0.2509 0.2299 7.79e-08 1kdg:A, 1naa:A, 1naa:B
29 4qi7:A 805 473 0.2032 0.1429 0.2431 1.92e-05 4qi7:B
30 4qi6:A 800 609 0.2650 0.1875 0.2463 8.20e-05 4qi3:A, 4qi3:B, 4qi4:A, 4qi5:A
31 2z5x:A 513 83 0.0530 0.0585 0.3614 0.15 2bxr:A, 2bxr:B, 2bxs:A, 2bxs:B, 2z5y:A
32 6cr0:A 430 59 0.0442 0.0581 0.4237 0.23
33 1rp0:A 278 34 0.0265 0.0540 0.4412 0.27 1rp0:B
34 3kpf:A 467 51 0.0353 0.0428 0.3922 0.34 1b37:A, 1b37:B, 1b37:C, 1b5q:A, 1b5q:B, 1b5q:C, 1h81:A, 1h81:B, 1h81:C, 1h82:A, 1h82:B, 1h82:C, 1h83:A, 1h83:B, 1h83:C, 1h84:A, 1h84:B, 1h84:C, 1h86:A, 1h86:B, 1h86:C, 3kpf:B, 3ku9:A, 3ku9:B, 3l1r:A, 3l1r:B
35 1o5w:C 512 83 0.0495 0.0547 0.3373 0.39 1o5w:A, 1o5w:B, 1o5w:D
36 1kht:B 191 53 0.0336 0.0995 0.3585 0.40 1kht:C
37 7qfd:A 458 108 0.0512 0.0633 0.2685 0.49 7qva:A
38 7qf8:A 494 305 0.1219 0.1397 0.2262 0.60
39 3ng7:X 427 33 0.0353 0.0468 0.6061 0.87 3k7m:X, 3k7q:X, 3k7t:A, 3k7t:B, 3ngc:X, 3nh3:X, 3nho:X, 3nk0:X, 3nk1:X, 3nk2:X, 3nn0:X, 3nn6:X
40 6knb:A 450 83 0.0406 0.0511 0.2771 0.97 6knc:A
41 6n7f:A 451 31 0.0283 0.0355 0.5161 1.0 6n7f:B, 6n7f:C, 6n7f:D
42 4a69:A 369 63 0.0247 0.0379 0.2222 2.4 4a69:B
43 5glg:A 471 36 0.0247 0.0297 0.3889 4.1 6ku6:B, 6ku6:H, 5zyn:B
44 1i8t:A 367 47 0.0300 0.0463 0.3617 4.3 1i8t:B
45 7aaw:A 315 51 0.0318 0.0571 0.3529 4.4 7aaw:B
46 3fpz:A 311 32 0.0247 0.0450 0.4375 4.6 3fpz:B, 4y4l:A, 4y4l:B, 4y4l:C, 4y4l:D
47 3h86:B 191 68 0.0300 0.0890 0.2500 4.8 3h86:A, 3h86:C, 3h86:G
48 7v94:A 1076 92 0.0424 0.0223 0.2609 5.4 7v93:A
49 4oic:B 305 79 0.0336 0.0623 0.2405 5.6
50 6brd:A 474 31 0.0283 0.0338 0.5161 6.4 6brd:B, 6brd:C, 5vqb:A, 5vqb:B, 5vqb:C
51 2dki:A 615 30 0.0194 0.0179 0.3667 6.5 2dkh:A
52 7qow:B 505 27 0.0194 0.0218 0.4074 8.0 3e2d:A, 3e2d:B, 7qow:A, 7qp8:A, 7qp8:B, 6qsq:A, 6t26:A, 6t26:B, 7yzz:A, 7yzz:B, 7z00:B
53 8grj:B 531 68 0.0300 0.0320 0.2500 8.8 6a2u:B, 6a2u:D, 8grj:D, 8hdd:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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