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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TTSITDLYNEVAKSDLGLVKANPLVSIIMTSHNTAQFIEASINSLLLQTYKNIEIIIVDDDSSDNTFEIASRIANTTSKV
RVFRLNSNLGTYFAKNTGILKSKGDIIFFQDSDDVCHHERIERCVNILLANKETIAVRCAYSRLAPETQHIIKVNNMDYR
LGFITLGMHRKVFQEIGFFNCTTKGSDDEFFHRIAKYYGKEKIKNLLLPLYYNTMRENSLFTDMVEWIDNHNIIQKMSDT
RQHYATLFQAMHNETASHDFKNLFQFPRIYDALPVPQEMSKLSNPKIPVYINICSIPSRIAQLRRIIGILKNQCDHFHIY
LDGYVEIPDFIKNLGNKATVVHCKDKDNSIRDNGKFILLEELIEKNQDGYYITCDDDIIYPSDYINTMIKKLNEYDDKAV
IGLHGILFPSSADRLVYSFYKPLEKDKAVNVLGTGTVSFRVSLFNQFSLSDFTHSGMADIYFSLLCKKNNILQICISRPA
NWLTEDNDEQQTQLIMENGPWGYSSIYPLVKNHPKFTDLIP

The query sequence (length=521) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8viw:B 545 540 0.9962 0.9523 0.9611 0.0 8vh7:A, 8vh7:B, 8vh8:A, 8vh8:B, 8vh8:C, 8vh8:D, 8viw:A, 8viw:D, 8viw:C
2 6h4f:B 318 105 0.0768 0.1258 0.3810 7.02e-10 6h1j:B, 6h21:A, 6h21:B, 6h21:C, 6h2n:A, 6h2n:B, 6h2n:C, 6h4f:C, 6h4f:F, 6h4f:O, 6h4f:P, 6h4f:E, 6h4f:G, 6h4f:Q, 6h4f:A, 6h4f:D, 6h4f:H, 6h4f:I, 6h4m:B, 6h4m:C, 6h4m:F, 6h4m:O, 6h4m:P, 6h4m:E, 6h4m:G, 6h4m:Q, 6h4m:A, 6h4m:D, 6h4m:H, 6h4m:I, 6hnq:B, 6hnq:C, 6hnq:F, 6hnq:O, 6hnq:P, 6hnq:E, 6hnq:G, 6hnq:Q, 6hnq:A, 6hnq:D, 6hnq:H, 6hnq:I
3 2z86:C 603 136 0.0768 0.0663 0.2941 1.52e-09 2z86:A, 2z86:B, 2z86:D, 2z87:A, 2z87:B
4 2z86:C 603 90 0.0403 0.0348 0.2333 5.4 2z86:A, 2z86:B, 2z86:D, 2z87:A, 2z87:B
5 1h7q:A 240 126 0.0672 0.1458 0.2778 1.39e-07 1h7l:A, 1qgq:A, 1qgs:A
6 1h7q:A 240 44 0.0288 0.0625 0.3409 9.4 1h7l:A, 1qgq:A, 1qgs:A
7 5tze:C 349 249 0.1190 0.1777 0.2490 1.08e-06 5tze:E, 5tzj:C, 5tzj:A, 5tzk:C
8 6yv8:A 346 122 0.0595 0.0896 0.2541 1.18e-05 6yv8:B, 6yv9:A, 6yv9:B
9 6pxu:B 532 123 0.0710 0.0695 0.3008 6.49e-05 6pxu:A
10 5mlz:A 355 121 0.0672 0.0986 0.2893 3.42e-04 5mm0:A, 5mm1:A
11 8bz6:A 606 107 0.0576 0.0495 0.2804 0.003 8bz6:B, 8bz6:C, 8bz6:D, 8bz6:E, 8bz6:F, 8bz7:A, 8bz7:B, 8bz7:C, 8bz7:D, 8bz7:E, 8bz7:F, 8bz8:A, 8bz8:B, 8bz8:C, 8bz8:D, 8bz8:E, 8bz8:F
12 6h0b:B 521 123 0.0633 0.0633 0.2683 0.19
13 3ckq:A 302 137 0.0595 0.1026 0.2263 0.20 3ckn:A, 3cko:A, 3ckv:A
14 5eke:C 307 171 0.0729 0.1238 0.2222 0.23 5eke:A, 5eke:B, 5eke:D, 5ekp:C, 5ekp:A, 5ekp:B, 5ekp:D
15 3f1y:A 318 156 0.0768 0.1258 0.2564 1.1 3f1y:C, 3kia:A, 3kia:C, 3o3p:A, 3o3p:B
16 7e6i:A 484 30 0.0326 0.0351 0.5667 2.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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