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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLV
PGLFKNEMKRRRDFYAAHP

The query sequence (length=99) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6wi7:A 206 99 1.0000 0.4806 1.0000 5.04e-70 2ckl:A, 8grm:M, 2h0d:A, 7nd1:H, 8pp7:K, 8pp7:M, 4r8p:K, 4r8p:M, 3rpg:B, 6wi8:A, 6wi8:B
2 6wi7:A 206 76 0.2424 0.1165 0.3158 4.54e-06 2ckl:A, 8grm:M, 2h0d:A, 7nd1:H, 8pp7:K, 8pp7:M, 4r8p:K, 4r8p:M, 3rpg:B, 6wi8:A, 6wi8:B
3 4s3o:C 95 93 0.4444 0.4632 0.4731 1.39e-28 4s3o:F
4 2djb:A 72 65 0.3434 0.4722 0.5231 1.02e-20
5 4orh:H 142 85 0.3131 0.2183 0.3647 3.50e-09 4ayc:A, 4ayc:B, 4orh:C, 4orh:G, 4orh:K, 4orh:L, 4whv:C, 4whv:D, 4whv:I, 4whv:J
6 2ep4:A 74 55 0.2121 0.2838 0.3818 2.56e-07
7 4r8p:L 254 76 0.2424 0.0945 0.3158 3.82e-06 2ckl:B, 8grm:N, 2h0d:B, 7nd1:A, 8pp7:L, 8pp7:N, 4r8p:N, 3rpg:C, 4s3o:B, 4s3o:E
8 2y43:A 88 67 0.2323 0.2614 0.3433 1.60e-05 2y43:B
9 6l8n:A 810 66 0.2121 0.0259 0.3182 3.56e-05
10 1chc:A 68 60 0.1919 0.2794 0.3167 9.60e-05
11 2ecn:A 70 53 0.1717 0.2429 0.3208 1.96e-04 5xek:A
12 5olm:B 132 81 0.2424 0.1818 0.2963 2.22e-04 5jpx:A, 5olm:A
13 7bbd:B 160 77 0.2424 0.1500 0.3117 3.96e-04 8a58:C, 8a58:D, 8c07:I, 8f1f:C, 8f1f:c, 6fga:A, 6fga:B, 6fga:C, 6fga:D, 6fga:E, 6fga:F, 6fga:G, 6fga:H, 5m93:B, 5m93:C, 7nbb:C, 5o44:E, 6s53:B, 6s53:A, 6s53:H, 6s53:G, 3zlz:B
14 7xyz:B 456 59 0.2222 0.0482 0.3729 4.53e-04 7xv2:A, 7xyy:A, 7xyy:B, 7xyz:A, 7xyz:C, 7xyz:D, 7xz0:A, 7xz0:B, 7xz1:A, 7xz1:B, 7xz2:A, 7xz2:B, 7xz2:C, 7xz2:D
15 2ecj:A 58 35 0.1616 0.2759 0.4571 0.001
16 6yxe:A 89 77 0.2121 0.2360 0.2727 0.002 6yxe:B
17 7r70:A 150 46 0.1515 0.1000 0.3261 0.002 5d0i:A, 5d0i:B, 5d0k:C, 5d0k:F, 5d0k:I, 5d0k:L, 7r70:B, 7r71:A
18 7dvq:M 191 56 0.1515 0.0785 0.2679 0.003 8i0r:K, 8i0s:K, 8i0t:K, 5z56:M, 5z58:M
19 2kiz:A 69 50 0.1515 0.2174 0.3000 0.006 5lg0:A, 5lg7:A, 7p2k:A
20 5d0m:C 60 43 0.1414 0.2333 0.3256 0.012 5ulh:C, 5ulk:C
21 6ff4:t 172 44 0.1313 0.0756 0.2955 0.026 8ch6:Z, 6ff7:t, 7qtt:Z
22 3ztg:A 92 78 0.2222 0.2391 0.2821 0.038 3ztg:B
23 1z6u:A 115 82 0.2222 0.1913 0.2683 0.070 1z6u:B
24 2ysl:A 73 58 0.1919 0.2603 0.3276 0.098 2ysj:A
25 4lad:B 69 67 0.1818 0.2609 0.2687 0.10
26 2yur:A 74 44 0.1616 0.2162 0.3636 0.11
27 4v3k:C 75 42 0.1313 0.1733 0.3095 0.12 7ojx:A, 4v3k:F, 4v3l:C
28 2l0b:A 91 43 0.1414 0.1538 0.3256 0.13
29 3fl2:A 116 78 0.1717 0.1466 0.2179 0.13
30 7t92:C 317 51 0.1616 0.0505 0.3137 0.13
31 1x4j:A 75 26 0.0909 0.1200 0.3462 0.30
32 8gui:L 73 52 0.1717 0.2329 0.3269 0.30 8guj:L, 8iej:A
33 2ect:A 78 25 0.1111 0.1410 0.4400 0.31
34 7zj3:A 86 44 0.1313 0.1512 0.2955 0.41 8a38:A, 8a38:B, 8a38:C, 8ams:C, 8ams:D, 7zj3:D, 7zj3:G, 7zj3:J
35 3zni:A 390 70 0.1818 0.0462 0.2571 0.48 4a49:A, 5axi:B, 5axi:A, 5axi:C, 9fqh:A, 9fqi:A, 9fqj:A, 9fqj:B, 8gcy:A, 2ldr:A, 3pfv:A, 3pfv:B, 8qng:A, 8qnh:A, 8qni:A, 8qtg:A, 8qth:A, 8qtj:A, 8qtk:A, 8vw4:A, 8vw4:B, 8vw5:A, 8vw5:B, 3zni:E, 3zni:I, 3zni:M
36 4tkp:B 63 51 0.1616 0.2540 0.3137 0.50
37 2ecw:A 85 53 0.1616 0.1882 0.3019 0.51
38 6a3z:A 56 44 0.1010 0.1786 0.2273 0.53
39 2csy:A 81 42 0.1212 0.1481 0.2857 0.56
40 1jm7:B 97 88 0.2222 0.2268 0.2500 0.72 8grq:M, 7jzv:B, 7lyb:N
41 8jwu:C 412 89 0.2424 0.0583 0.2697 0.89 8jwj:A, 8jwj:C, 8jws:A, 8jws:B, 8jws:C, 8jwu:A, 8jwu:B
42 7dco:M 176 48 0.1212 0.0682 0.2500 0.96 5gm6:a
43 2ea6:A 69 29 0.1010 0.1449 0.3448 0.97
44 5ait:A 129 32 0.1111 0.0853 0.3438 1.1 5aiu:A, 4ap4:A, 3ng2:A, 3ng2:B, 4ppe:A, 4ppe:B, 2xeu:A
45 5ait:A 129 32 0.1111 0.0853 0.3438 1.1 5aiu:A, 4ap4:A, 3ng2:A, 3ng2:B, 4ppe:A, 4ppe:B, 2xeu:A
46 6mm1:D 135 64 0.2020 0.1481 0.3125 1.2 6mm1:A, 6mm1:B, 6mm1:C
47 2ecv:A 85 54 0.1515 0.1765 0.2778 1.8
48 5din:B 124 78 0.1919 0.1532 0.2436 1.9 5din:A
49 8gui:K 72 52 0.1616 0.2222 0.3077 2.0 8guj:K, 8iej:M, 5trb:A
50 1p4v:A 295 70 0.1616 0.0542 0.2286 2.2 9gac:A, 9gac:C, 9gaf:A, 9gaf:C, 2gl9:B, 2gl9:D, 3ljq:C, 1p4v:C, 4r4y:A
51 1rmd:A 116 42 0.1515 0.1293 0.3571 2.2
52 2lxh:C 58 44 0.1212 0.2069 0.2727 2.3 2lxp:C
53 5zbu:A 74 56 0.1515 0.2027 0.2679 2.4 5zbu:D, 5zc4:A, 5zc4:D
54 6k2k:A 57 51 0.1818 0.3158 0.3529 2.6 6m2c:E, 6m2c:F, 6m2c:G, 6m2c:H, 6m2d:A, 6m2d:B, 6m2d:C, 6m2d:D, 6m2d:E, 6m2d:F
55 5h7r:D 124 45 0.1212 0.0968 0.2667 3.1 5h7s:D, 5h7s:B
56 5dka:A 96 24 0.1111 0.1146 0.4583 3.3 5dka:B, 8gbq:B, 8gcb:B
57 4a0c:F 80 45 0.1313 0.1625 0.2889 3.6 8ij1:R, 7shk:R
58 6w7z:B 71 41 0.1212 0.1690 0.2927 3.6 6w9a:B, 6w9a:D, 6w9d:B, 6w9d:E, 6w9d:H
59 6f98:A 78 29 0.1010 0.1282 0.3448 3.7
60 7yui:B 232 35 0.1212 0.0517 0.3429 3.9 3b08:K, 3b08:B, 3b08:E, 3b08:H, 3b0a:B
61 5mwl:A 421 38 0.1212 0.0285 0.3158 4.1 5mw8:A, 5mwl:B, 5mwm:A
62 5a2a:A 452 34 0.1616 0.0354 0.4706 4.3 5a2b:A, 5a2c:A
63 1nak:H 214 34 0.1212 0.0561 0.3529 4.5 1nak:I
64 2lgv:A 100 22 0.1010 0.1000 0.4545 4.6 4a0c:D, 8b3g:R, 8b3i:R, 7b5l:R, 7b5m:R, 7b5n:R, 7b5s:R, 8cdk:R, 3dpl:R, 3dqv:R, 3dqv:Y, 4f52:B, 4f52:D, 8gq6:E, 8gq6:D, 8h33:D, 8h33:K, 8h33:L, 8h33:E, 8h34:R, 8h34:Q, 8h34:E, 8h34:D, 8h34:L, 8h34:K, 8h35:E, 8h35:D, 8h35:L, 8h35:K, 8h35:R, 8h35:Q, 8h35:W, 8h35:X, 8h36:E, 8h36:D, 8h37:E, 8h37:D, 8h37:R, 8h37:Q, 8h38:R, 8h3a:R, 8h3f:R, 8h3q:E, 8h3r:E, 8h3r:D, 2hye:D, 8jaq:R, 8jaq:V, 8jas:R, 8jas:V, 8jav:R, 8jav:V, 1ldj:B, 1ldk:C, 5n4w:R, 8or0:B, 8or2:B, 8or3:B, 4p5o:B, 4p5o:D, 7plo:T, 8pql:K, 8q7h:C, 8q7h:D, 8q7r:R, 8qu8:E, 8r5h:R, 6r7i:R, 6r7n:R, 8rhz:C, 8rhz:D, 3rtr:B, 3rtr:D, 3rtr:F, 3rtr:H, 8rwz:R, 8rx0:R, 6ttu:R, 1u6g:B, 8wqa:J, 8wqa:I, 8wqb:I, 8wqb:E, 8wqc:F, 8wqc:J, 8wqe:J, 8wqe:I, 8wqf:I, 8wqf:E, 8wqg:F, 8wqg:J, 8wqh:J, 8wqh:B, 7z8b:R, 7z8r:R, 7z8t:R, 7z8v:R, 7zbz:R
65 7jzv:A 253 57 0.1717 0.0672 0.2982 4.6 8grq:K, 1jm7:A, 7lyb:M
66 2eci:A 86 23 0.0909 0.1047 0.3913 4.9
67 7ane:a 408 30 0.1212 0.0294 0.4000 5.0
68 8eaz:A 254 35 0.1212 0.0472 0.3429 5.3 8bvl:A, 8bvl:B, 8eaz:B, 7yuj:A, 7yuj:B
69 2egp:A 79 55 0.1313 0.1646 0.2364 5.4
70 2ma6:A 61 44 0.1414 0.2295 0.3182 6.4
71 3zok:A 365 24 0.1111 0.0301 0.4583 6.6 3zok:B, 3zok:C, 3zok:D
72 5ywr:B 87 39 0.1313 0.1494 0.3333 6.7
73 7oni:R 86 24 0.0909 0.1047 0.3750 7.0 2ecl:A, 6v9i:R
74 8ets:V 443 32 0.1212 0.0271 0.3750 9.0 8ets:X, 8ets:T, 8etu:V, 8etu:X, 8etu:T, 8etw:V, 8etw:X, 8etw:T, 8eu9:V, 8eu9:X, 8eu9:T, 8euf:V, 8euf:X, 8euf:T, 6gej:T, 6gej:V, 6gej:X, 6gen:T, 6gen:V, 6gen:X
75 1iym:A 55 34 0.1010 0.1818 0.2941 9.3
76 8q7h:A 1403 38 0.1313 0.0093 0.3421 9.7
77 7ohr:w 198 24 0.1010 0.0505 0.4167 9.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218