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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TTLFRWPVRVYYEDTAAGGVVYHASYVAFYERARTEMLRHHHFSQQALMAERVAFVVRKMTVEYYAPARLDDMLEIQTEI
TSMRGTSLVFTQRIVNAENTLLNEAEVLVVCVDPLKMKPRALPKSIVAEF

The query sequence (length=130) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5kl9:A 134 130 0.9923 0.9627 0.9923 3.03e-94 5kl9:D, 5t06:A, 5t06:C, 5t07:A, 5t07:D, 5t07:B, 5t07:C
2 4i45:A 129 131 0.2385 0.2403 0.2366 6.18e-07
3 2gf6:A 134 120 0.2077 0.2015 0.2250 3.19e-06 2gf6:B, 2gf6:C, 2gf6:D
4 6snh:X 479 81 0.1615 0.0438 0.2593 1.3 6sni:X
5 8j0s:D 469 30 0.1000 0.0277 0.4333 1.6 6foc:F, 6foc:D, 6foc:E, 8g08:F, 8g08:D, 8g09:D, 8g0a:E, 8g0a:F, 8g0c:F, 8g0d:D, 8g0d:E, 8g0e:E, 8g0e:F, 8j0s:F, 8j0t:D, 8j0t:F, 7jg5:F, 7jga:E, 8jr0:D, 8jr0:F, 7njk:D, 7njk:E, 7njk:F, 7njl:D, 7njl:E, 7njl:F, 7njm:D, 7njm:E, 7njm:F, 7njn:D, 7njn:E, 7njn:F, 7njo:D, 7njo:E, 7njo:F, 7njp:D, 7njp:E, 7njp:F, 7njq:D, 7njq:E, 7njq:F, 7njr:D, 7njr:E, 7njr:F, 7njs:D, 7njs:E, 7njs:F, 7nk7:D, 7nk7:E, 7nk7:F, 7nkh:D, 7nkh:E, 7nkh:F, 7nkj:D, 7nkj:E, 7nkj:F, 7y5a:D, 7y5a:F, 7y5b:D, 7y5b:E, 7y5b:F, 7y5c:D, 7y5c:E, 7y5c:F
6 2cye:C 133 108 0.2308 0.2256 0.2778 3.1 2cye:A, 2cye:B, 2cye:D
7 8eop:A 1687 27 0.0846 0.0065 0.4074 3.3
8 4mmo:A 437 57 0.1231 0.0366 0.2807 3.8
9 4zrb:E 128 43 0.1000 0.1016 0.3023 4.0 4zrb:A, 4zrb:D, 4zrb:B, 4zrb:C, 4zrb:G, 4zrb:H, 4zrb:F
10 8ee6:A 1808 27 0.0846 0.0061 0.4074 4.7 8edw:A
11 2w3x:E 144 127 0.2231 0.2014 0.2283 6.8 2w3x:A, 2w3x:C, 2w3x:D, 2w3x:F
12 8oin:Aa 381 44 0.0923 0.0315 0.2727 9.9 8oip:Aa, 8oiq:Aa, 8oir:Aa, 8ois:Aa, 8oit:Aa

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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