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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TTERQRTAPGLLAALHQARSPLDAQALAELSTAFSLPPGEIAATASFYHFFQTPPARYQIHFVDHVVDHHAGVAALCNHL
CAAFAIQPGQRTADARLFVGWTACAGLSDQAPAALINGRPMPRLDAARIDALIEKIQAQIPMDQWPTEWFAVTNAIHRHG
PLLTWLDTTPAEAVFEHPTAHDPDAILQAVTDAGLRGRGGAGFPTATKWRFCRENADPERFLICNADEGEPGTFKDRVLL
TRYPEHLFAGMILAARAIGADKAILYLRYEYQYLLPQLEAARERIASAQATVPQAERVTLEIALGAGAYVCGEESALIES
LEGKPGRPRVRPPYPVTQGYLGHPTVVNNVETLVAVAAIVGNGAAWWRALGTPDSSGPKLFCVSGDVAQPGLYEFPYGVA
LGDVVTAARPLGTRYAVQVSGPSGTLLPATPEQLARPLAFEALPCNGTVMVFDVRRDPVAIVHHFARFFAHESCGFCTPC
RVGTQLIAKTFEKIAAGYATRFDLERLAPALEAMRLASNCGFGLSAGNPVRDLIAHFRQQLEAQLQPHDFIPAFSLDAEL
AATRRLHLAQFEQPEV

The query sequence (length=576) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5xfa:A 581 580 0.9931 0.9845 0.9862 0.0 5xf9:A, 5xf9:E, 5xfa:E
2 9fdv:B 419 376 0.2778 0.3819 0.4255 7.20e-84 9fdj:B, 9fdj:D, 9fdk:B, 9fdk:D, 9fdv:D, 9fe0:B, 9fe0:D, 9fe5:B, 9fe5:D, 9fe7:B, 9fe7:D, 9fe8:B, 9fe8:D, 9fea:B, 9fea:D, 9fif:B, 9fif:D, 9fih:B, 9fih:D, 9fii:B, 9fii:D, 9fij:B, 9fij:D, 9fil:B, 9fil:D, 6hl2:B, 6hl2:D, 6hl3:B, 6hl3:D, 6hl4:B, 6hl4:D, 6hla:B, 6hla:D, 6hli:B, 6hli:D, 6hlj:B, 6hlj:D, 6hlm:B, 6hlm:D, 7q5y:C, 7q5y:I, 7q5y:O, 7q5y:U, 6q9c:B, 6q9c:D, 6q9g:B, 6q9g:D, 6q9j:B, 6q9j:D, 6q9k:B, 6q9k:D, 8qg1:B, 8qg1:D, 8qgw:B, 8qgw:D, 8qh4:B, 8qh4:D, 8qh7:B, 8qh7:D, 8qhk:B, 8qhk:D, 6r7p:B, 6r7p:D, 6saq:B, 6saq:D
3 4hea:1 437 412 0.2812 0.3707 0.3932 3.86e-82 2fug:1, 2fug:A, 2fug:J, 2fug:S, 4hea:B, 6i0d:1, 6i0d:B, 6i1p:1, 6i1p:B, 3i9v:1, 3i9v:A, 3iam:1, 3iam:A, 3ias:1, 3ias:A, 3ias:J, 3ias:S, 3m9s:1, 3m9s:A, 6q8o:1, 6q8o:B, 6q8w:1, 6q8w:B, 6q8x:1, 6q8x:B, 6y11:1, 6y11:B, 2ybb:1, 6ziy:1, 6zjl:1, 6zjn:1, 6zjy:1
4 8a6t:B 630 379 0.2535 0.2317 0.3852 6.65e-80 8a6t:E, 8bew:B, 8bew:E
5 7t2r:B 425 381 0.2569 0.3482 0.3885 1.38e-76 7t2r:G, 7t30:B, 7t30:G
6 8e9h:F 436 384 0.2587 0.3417 0.3880 3.52e-74 8e9g:F, 8e9i:F
7 7p61:F 442 409 0.2604 0.3394 0.3667 5.04e-73 7awt:F, 7nyr:F, 7nyu:F, 7nyv:F, 7nz1:F, 7p62:F, 7p63:F, 7p64:F, 7p69:F, 7p7c:F, 7p7e:F, 7p7j:F, 7p7k:F, 7p7l:F, 7p7m:F, 7z7r:F, 7z7s:F, 7z7t:F, 7z7v:F, 7z80:F, 7z83:F, 7z84:F, 7zc5:F, 7zci:F
8 7b0n:F 460 405 0.2413 0.3022 0.3432 1.04e-72 6gcs:B, 7o6y:B, 7o71:B, 6rfq:B, 6rfr:B, 6rfs:B, 6y79:B, 6yj4:F
9 7v2c:A 433 379 0.2465 0.3279 0.3747 8.79e-72 7ak5:F, 7ak6:F, 7b93:F, 8c2s:F, 8ca3:F, 8ca4:F, 8ca5:F, 7dgq:8, 7dgr:8, 7dgs:8, 7dgz:8, 7dh0:8, 7dkf:82, 6g2j:F, 6g72:F, 5gpn:c, 5gup:B, 8iao:F, 8iap:F, 8ib4:F, 8ib5:F, 8ib9:F, 8iba:F, 8ibd:F, 8ibe:F, 8ic2:F, 8ic3:F, 5lc5:F, 5ldw:F, 5ldx:F, 5lnk:1, 5o31:F, 8olt:F, 8om1:F, 7psa:F, 8pw5:1, 8pw6:1, 8pw7:1, 8q0a:F, 8q0f:F, 8q0j:F, 8q0m:F, 8q0o:F, 8q0q:F, 8q1p:F, 8q1u:F, 8q1y:F, 8q25:F, 8q45:F, 8q46:F, 8q47:F, 8q48:F, 8q49:F, 8q4a:F, 6q9d:V1, 6qa9:V1, 6qbx:V1, 6qc2:V1, 6qc3:V1, 6qc4:V1, 6qc5:V1, 6qc6:V1, 6qc7:V1, 6qc8:V1, 6qc9:V1, 6qca:V1, 6qcf:V1, 7qsd:F, 7qsk:F, 7qsl:F, 7qsm:F, 7qsn:F, 7qso:F, 7r41:F, 7r42:F, 7r43:F, 7r44:F, 7r45:F, 7r46:F, 7r47:F, 7r48:F, 7r4c:F, 7r4d:F, 7r4f:F, 7r4g:F, 8rgp:1, 8rgq:1, 8rgr:1, 8rgt:1, 8ud1:1F, 8ueo:1F, 8uep:1F, 8ueq:1F, 8uer:1F, 8ues:1F, 8uet:1F, 8ueu:1F, 8uev:1F, 8uew:1F, 8uex:1F, 8uey:1F, 8uez:1F, 8ugh:1F, 8ugi:1F, 8ugj:1F, 8ugn:1F, 8ugn:5F, 8ugr:1F, 8ugr:5F, 7v2d:A, 7v2e:A, 7v2f:A, 7v2h:A, 7v2k:A, 7v2r:A, 7v30:A, 7v31:A, 7v32:A, 7v33:A, 7v3m:A, 7vb7:A, 7vbn:A, 7vbz:A, 7vwj:A, 7vxp:A, 7vxu:A, 7vy8:A, 7vya:A, 7vyf:A, 7vyh:A, 7vyn:A, 7vz1:A, 7vzv:A, 7vzw:A, 7w00:A, 7w0h:A, 7w0r:A, 7w0y:A, 7w1o:A, 7w1p:A, 7w1t:A, 7w1u:A, 7w1v:A, 7w1z:A, 7w20:A, 7w2k:A, 7w2l:A, 7w2r:A, 7w2u:A, 7w2y:A, 7w31:A, 7w32:A, 7w35:A, 7w4c:A, 7w4d:A, 7w4e:A, 7w4f:A, 7w4g:A, 7w4j:A, 7w4k:A, 7w4l:A, 7w4m:A, 7w4n:A, 7w4q:A, 5xtb:A, 5xtd:A, 5xth:A, 5xti:A, 5xti:BA, 7zd6:1, 7zdh:1, 7zdj:1, 7zdm:1, 7zdp:1, 7zeb:1, 6zk9:1, 6zkc:1, 6zkd:1, 6zke:1, 6zkf:1, 6zkg:1, 6zkh:1, 6zki:1, 6zkj:1, 6zkk:1, 6zkl:1, 6zkm:1, 6zkn:1, 6zko:1, 6zkp:1, 6zkq:1, 6zkr:1, 6zks:1, 6zkt:1, 6zku:1, 6zkv:1, 6zr2:F, 6ztq:F
10 7q4v:B 599 358 0.2326 0.2237 0.3743 5.55e-71 8a5e:B, 7q4v:F, 7q4w:B, 7q4w:F
11 8gym:v1 442 392 0.2292 0.2986 0.3367 8.43e-70 8b6f:AD, 8bqs:AD, 8gym:V1, 8gzu:v1, 8gzu:V1, 7tgh:V1
12 7p8n:B 613 458 0.2726 0.2561 0.3428 1.30e-69 7p5h:B, 7p5h:E, 7p5h:b, 7p5h:e, 7p8n:b, 7p91:b, 7p91:B, 7p92:B
13 8b9z:F 441 387 0.2344 0.3061 0.3488 2.16e-69 8ba0:F, 8esw:V1, 8esz:V1
14 8oh5:B 584 358 0.2292 0.2260 0.3687 4.46e-69 8oh5:E, 8oh5:H, 8oh5:K, 8oh9:B, 8oh9:E, 8oh9:H, 8oh9:K
15 7zm7:B 456 388 0.2396 0.3026 0.3557 2.41e-68 7zmb:B, 7zmg:B
16 7aqr:F 434 376 0.2309 0.3065 0.3537 3.00e-68 7a23:A, 7a24:A, 7ar7:F, 7ar8:F, 7arb:F, 8bed:F, 8bpx:F, 8bq5:F, 8bq6:F, 8e73:V1, 6x89:V1
17 6tg9:B 493 368 0.2413 0.2819 0.3777 1.02e-67 6tg9:F, 6tga:B, 6tga:F
18 8qby:F 421 386 0.2309 0.3159 0.3446 1.57e-67
19 6vw7:D 514 394 0.2604 0.2918 0.3807 2.37e-67 6vw7:B, 6vw8:B, 6vw8:D
20 7arc:F 430 423 0.2413 0.3233 0.3286 4.41e-67 7ard:F
21 7vw6:B 560 559 0.3264 0.3357 0.3363 3.34e-65 7e5z:B, 8j83:B, 7xqw:B
22 8iuf:V1 504 391 0.2257 0.2579 0.3325 2.80e-64 8j9h:V1, 8j9i:V1, 8j9j:V1
23 7p5h:C 156 111 0.0556 0.2051 0.2883 4.13e-09 7p5h:F, 7p5h:c, 7p5h:f, 7p8n:c, 7p8n:C, 7p91:c, 7p91:C, 7p92:C
24 7awt:E 156 127 0.0590 0.2179 0.2677 1.08e-08 7nyr:E, 7nyu:E, 7nyv:E, 7nz1:E, 7p61:E, 7p62:E, 7p63:E, 7p64:E, 7p69:E, 7p7c:E, 7p7e:E, 7p7j:E, 7p7k:E, 7p7l:E, 7p7m:E, 7z7r:E, 7z7s:E, 7z7t:E, 7z7v:E, 7z80:E, 7z83:E, 7z84:E, 7zc5:E, 7zci:E
25 3iam:2 179 130 0.0590 0.1899 0.2615 2.41e-08 2fug:2, 2fug:B, 2fug:K, 2fug:T, 4hea:2, 4hea:C, 6i0d:2, 6i0d:C, 6i1p:2, 6i1p:C, 3i9v:2, 3i9v:B, 3iam:B, 3ias:2, 3ias:B, 3ias:K, 3ias:T, 3m9s:2, 3m9s:B, 6q8o:2, 6q8o:C, 6q8w:2, 6q8w:C, 6q8x:2, 6q8x:C, 6y11:2, 6y11:C, 2ybb:2, 6ziy:2, 6zjl:2, 6zjn:2, 6zjy:2
26 8oh5:A 150 128 0.0590 0.2267 0.2656 1.69e-06 8oh5:D, 8oh5:G, 8oh5:J, 8oh9:A, 8oh9:D, 8oh9:G, 8oh9:J
27 8a5e:C 156 138 0.0625 0.2308 0.2609 2.30e-06 7q4v:C, 7q4v:G, 7q4w:C, 7q4w:G
28 9fdk:C 160 112 0.0486 0.1750 0.2500 1.91e-05 9fdj:A, 9fdj:C, 9fdk:A, 9fdv:A, 9fdv:C, 9fe0:A, 9fe0:C, 9fe5:A, 9fe5:C, 9fe7:A, 9fe7:C, 9fe8:A, 9fe8:C, 9fea:A, 9fea:C, 9fif:A, 9fif:C, 9fih:A, 9fih:C, 9fii:A, 9fii:C, 9fij:A, 9fij:C, 9fil:A, 9fil:C, 6hl2:A, 6hl2:C, 6hl3:A, 6hl3:C, 6hl4:A, 6hl4:C, 6hla:A, 6hla:C, 6hli:A, 6hli:C, 6hlj:A, 6hlj:C, 6hlm:A, 6hlm:C, 7q5y:E, 7q5y:K, 7q5y:Q, 7q5y:W, 6q9c:A, 6q9c:C, 6q9g:A, 6q9g:C, 6q9j:A, 6q9j:C, 6q9k:A, 6q9k:C, 8qg1:A, 8qg1:C, 8qgw:A, 8qgw:C, 8qh4:A, 8qh4:C, 8qh7:A, 8qh7:C, 8qhk:A, 8qhk:C, 6r7p:A, 6r7p:C, 6saq:A, 6saq:C
29 7t2r:C 152 132 0.0556 0.2105 0.2424 2.12e-05 7t2r:H
30 6tg9:G 148 113 0.0556 0.2162 0.2832 6.10e-05 6tg9:C, 6tga:G, 6tga:C
31 6vw8:C 152 138 0.0608 0.2303 0.2536 1.67e-04 6vw7:A, 6vw7:C, 6vw8:A
32 8e9g:E 233 85 0.0399 0.0987 0.2706 8.77e-04 8e9h:E, 8e9i:E
33 7b0n:E 216 85 0.0365 0.0972 0.2471 0.007 6gcs:H, 7o6y:H, 7o71:H, 6rfq:H, 6rfr:H, 6rfs:H, 6y79:H, 6yj4:E
34 8a6t:C 151 107 0.0347 0.1325 0.1869 0.013 8a6t:F, 8bew:C, 8bew:F
35 5gup:E 197 122 0.0451 0.1320 0.2131 0.014
36 7v2c:O 217 122 0.0451 0.1198 0.2131 0.019 7ak5:E, 7ak6:E, 7b93:E, 8c2s:E, 8ca3:E, 8ca4:E, 8ca5:E, 7dgq:9, 7dgr:9, 7dgs:9, 7dgz:9, 7dh0:9, 7dkf:92, 6g2j:E, 6g72:E, 5gpn:d, 8iao:E, 8iap:E, 8ib4:E, 8ib5:E, 8ib9:E, 8iba:E, 8ibd:E, 8ibe:E, 8ic2:E, 8ic3:E, 5lc5:E, 5ldw:E, 5ldx:E, 5lnk:2, 5o31:E, 8olt:E, 8om1:E, 7psa:E, 8pw5:2, 8pw6:2, 8pw7:2, 8q0a:E, 8q0f:E, 8q0j:E, 8q0m:E, 8q0o:E, 8q0q:E, 8q1p:E, 8q1u:E, 8q1y:E, 8q25:E, 8q45:E, 8q46:E, 8q47:E, 8q48:E, 8q49:E, 8q4a:E, 6q9d:V2, 6qa9:V2, 6qbx:V2, 6qc2:V2, 6qc3:V2, 6qc4:V2, 6qc5:V2, 6qc6:V2, 6qc7:V2, 6qc8:V2, 6qc9:V2, 6qca:V2, 6qcf:V2, 7qsd:E, 7qsk:E, 7qsl:E, 7qsm:E, 7qsn:E, 7qso:E, 7r41:E, 7r42:E, 7r43:E, 7r44:E, 7r45:E, 7r46:E, 7r47:E, 7r48:E, 7r4c:E, 7r4d:E, 7r4f:E, 7r4g:E, 8rgp:2, 8rgq:2, 8rgr:2, 8rgt:2, 8ud1:1E, 8ueo:1E, 8uep:1E, 8ueq:1E, 8uer:1E, 8ues:1E, 8uet:1E, 8ueu:1E, 8uev:1E, 8uew:1E, 8uex:1E, 8uey:1E, 8uez:1E, 8ugh:1E, 8ugi:1E, 8ugj:1E, 8ugn:1E, 8ugn:5E, 8ugr:1E, 8ugr:5E, 7v2d:O, 7v2e:O, 7v2f:O, 7v2h:O, 7v2k:O, 7v2r:O, 7v30:O, 7v31:O, 7v32:O, 7v33:O, 7v3m:O, 7vb7:O, 7vbn:O, 7vbz:O, 7vwj:O, 7vxp:O, 7vxu:O, 7vy8:O, 7vya:O, 7vyf:O, 7vyh:O, 7vyn:O, 7vz1:O, 7vzv:O, 7vzw:O, 7w00:O, 7w0h:O, 7w0r:O, 7w0y:O, 7w1o:O, 7w1p:O, 7w1t:O, 7w1u:O, 7w1v:O, 7w1z:O, 7w20:O, 7w2k:O, 7w2l:O, 7w2r:O, 7w2u:O, 7w2y:O, 7w31:O, 7w32:O, 7w35:O, 7w4c:O, 7w4d:O, 7w4e:O, 7w4f:O, 7w4g:O, 7w4j:O, 7w4k:O, 7w4l:O, 7w4m:O, 7w4n:O, 7w4q:O, 5xtb:O, 5xtd:O, 5xth:O, 5xti:O, 5xti:BO, 7zd6:2, 7zdh:2, 7zdj:2, 7zdm:2, 7zdp:2, 7zeb:2, 6zk9:2, 6zkc:2, 6zkd:2, 6zke:2, 6zkf:2, 6zkg:2, 6zkh:2, 6zki:2, 6zkj:2, 6zkk:2, 6zkl:2, 6zkm:2, 6zkn:2, 6zko:2, 6zkp:2, 6zkq:2, 6zkr:2, 6zks:2, 6zkt:2, 6zku:2, 6zkv:2, 6zr2:E, 6ztq:E
37 8rbq:C 477 79 0.0451 0.0545 0.3291 0.063 8ahx:C, 8rb8:C, 8rb9:C, 8rbm:C
38 8b9z:E 214 119 0.0417 0.1121 0.2017 0.25 8ba0:E, 8esw:V2, 8esz:V2
39 7zc6:C 435 234 0.0955 0.1264 0.2350 0.42
40 7ane:e 809 78 0.0347 0.0247 0.2564 2.0
41 5dx5:A 399 190 0.0764 0.1103 0.2316 2.4 5dx5:B
42 7zmb:H 221 95 0.0365 0.0950 0.2211 2.4 7zm7:H, 7zmg:H
43 8y6o:R 157 33 0.0278 0.1019 0.4848 3.0
44 3fd5:B 355 37 0.0260 0.0423 0.4054 3.7 3fd5:A, 3fd6:A, 3fd6:B
45 8a47:C 297 42 0.0243 0.0471 0.3333 5.8
46 3b2z:F 293 56 0.0295 0.0580 0.3036 8.4 3b2z:A, 3b2z:B, 3b2z:C, 3b2z:D, 3b2z:E, 3b2z:G, 3b2z:H, 2rjp:A, 2rjp:B, 2rjp:C, 2rjp:D, 4wk7:A, 4wke:A, 4wki:A
47 8rph:F 520 148 0.0573 0.0635 0.2230 8.9
48 7vo5:A 276 68 0.0417 0.0870 0.3529 9.2
49 4pfu:B 542 43 0.0226 0.0240 0.3023 9.5 5hm4:B, 4pfu:A, 4pfw:A, 4pfw:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218