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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TRTLPPGVSDERFDAALQRFRDVVGDKWVLSTADELEAFRDPYPVGAAEANLPSAVVSPESTEQVQDIVRIANEYGIPLH
PVSTGKNNGYGGAAPRLSGSVIVKTGERMNRILEVNEKYGYALLEPGVTYFDLYEYLQSHDSGLMLDCPDLGWGSVVGNT
LDRGVGYTPYGDHFMWQTGLEVVLPQGEVMRTGMGALPGSDAWQLFPYGFGPFPDGMFTQSNLGIVTKMGIALMQRPPAS
QSFLITFDKEEDLEQIVDIMLPLRINMAPLQNVPVLRNIFMDAAAVSKRTEWFDGDGPMPAEAIERMKKDLDLGFWNFYG
TLYGPPPLIEMYYGMIKEAFGKIPGARFFTHEERDDRGGHVLQDRHKINNGIPSLDELQLLDWVPNGGHIGFVPVSAPDG
REAMKQFEMVRNRANEYNKDYMAQFIIGLREMYHVCLFIYDTADPEAREEILQMTKVLVREAAEAGYGEYRTHNALMDDV
MATFNWGDGALLKFHEKIKDALDPNGIIAPGKSGIWPQRFRGQNL

The query sequence (length=525) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8bam:A 525 525 0.9924 0.9924 0.9924 0.0 8bam:B, 8bap:A, 8bap:B, 8bap:C, 8bap:D, 8bap:E, 8bap:F, 8bap:G, 8bap:H, 8bap:I, 8bap:J, 8bap:K, 8bap:L, 8bap:M, 8bap:N, 8bap:O, 8bap:P, 5fxd:A, 5fxd:B, 5fxe:A, 5fxe:B, 5fxf:A, 5fxf:B, 5fxp:A, 5fxp:B, 7ywu:A, 7ywu:B, 7ywu:C, 7ywu:D, 7ywu:E, 7ywu:F, 7ywu:G, 7ywu:H, 7ywv:A, 7ywv:B, 7ywv:C, 7ywv:D, 7ywv:E, 7ywv:F, 7ywv:G, 7ywv:H
2 7pbg:A 525 524 0.5181 0.5181 0.5191 0.0 7pbg:B, 7pbi:A, 7pbi:B, 7pbi:C, 7pbi:D, 7pbi:E, 7pbi:F, 7pbi:G, 7pbi:H
3 1ahu:A 555 546 0.4686 0.4432 0.4505 3.99e-171 1ahu:B, 1ahv:A, 1ahv:B, 1ahz:A, 1ahz:B, 1dzn:A, 1dzn:B, 1e0y:A, 1e0y:B, 1e8g:A, 1e8g:B, 1e8h:A, 1e8h:B, 5mxj:A, 5mxj:B, 5mxu:A, 5mxu:B, 1qlt:A, 1qlt:B, 1qlu:A, 1qlu:B, 1vao:A, 1vao:B, 2vao:A, 2vao:B, 1w1j:A, 1w1j:B, 1w1k:A, 1w1k:B, 1w1l:A, 1w1l:B, 1w1m:A, 1w1m:B
4 1dii:A 515 515 0.3886 0.3961 0.3961 3.65e-128 1dii:B, 1diq:A, 1diq:B, 1wve:A, 1wve:B, 1wvf:A
5 7qh2:C 467 209 0.1181 0.1328 0.2967 1.53e-13 7qh2:F
6 3pm9:A 465 249 0.1276 0.1441 0.2691 9.16e-11 3pm9:B, 3pm9:C, 3pm9:D, 3pm9:E, 3pm9:F
7 6lpn:B 467 190 0.0990 0.1113 0.2737 8.43e-09 6lpn:A, 6lpp:A, 6lpp:B, 6lpq:A, 6lpq:B, 6lpt:A, 6lpt:B, 6lpu:A, 6lpu:B, 6lpx:A, 6lpx:B
8 8jdb:A 456 236 0.1200 0.1382 0.2669 2.53e-08 8jdc:A, 8jdd:A, 8jde:A, 8jdf:A, 8jdg:A, 8jdn:A, 8jdo:A, 8jdp:A, 8jdq:A, 8jdr:A, 8jds:A, 8jdt:A, 8jdu:A, 8jdv:A, 8jdx:A, 8jdy:A, 8jdz:A
9 5adz:C 557 201 0.0914 0.0862 0.2388 2.04e-05 5adz:B, 5adz:D, 5ae1:B, 5ae2:B, 5ae2:C, 5ae2:D, 5ae3:A, 5ae3:B, 5ae3:C, 5ae3:D, 4bby:B, 4bby:C, 4bby:D, 4bc7:B, 4bc7:C, 4bc7:D, 4bc9:B, 4bc9:C, 4bc9:D, 4bca:B, 4bca:C, 4bca:D, 6gou:D, 6gou:A, 6gou:B, 6gou:C
10 5adz:A 566 201 0.0914 0.0848 0.2388 2.28e-05 5ae1:A, 5ae1:C, 5ae1:D, 5ae2:A, 4bby:A, 4bc7:A, 4bc9:A, 4bca:A
11 6v42:A 466 85 0.0552 0.0622 0.3412 2.13e-04 6v42:B, 6v43:A, 6v43:B
12 2uuu:A 550 152 0.0781 0.0745 0.2697 2.63e-04 2uuu:B, 2uuu:C, 2uuu:D, 2uuv:A, 2uuv:B, 2uuv:C, 2uuv:D
13 3rj8:A 473 141 0.0667 0.0740 0.2482 0.018 3rja:A
14 8w8j:A 572 152 0.0629 0.0577 0.2171 0.35 8w8j:B, 8w8l:A, 8w8l:B, 8w9i:A, 8w9i:B
15 1nw8:A 272 133 0.0629 0.1213 0.2481 0.43 1eg2:A, 1nw5:A, 1nw6:A, 1nw7:A
16 8qnc:A 486 95 0.0457 0.0494 0.2526 0.58 8qmy:A, 8qmy:B, 8qmy:C, 8qnb:A, 8qnr:A
17 2vnv:B 128 65 0.0438 0.1797 0.3538 1.1 4aoc:A, 4aoc:B, 4aoc:C, 4aoc:D, 4aoc:E, 2vnv:A, 2vnv:C, 2vnv:D, 2vnv:E, 2wr9:A, 2wr9:D, 2wr9:B, 2wr9:C, 2wra:A
18 3v6i:A 187 72 0.0438 0.1230 0.3194 1.7
19 6wh3:A 334 88 0.0476 0.0749 0.2841 2.0 6wh3:B, 6wh3:C, 6wh3:D, 6wh3:E, 6wh3:F, 6wh3:G, 6wh3:H, 6wh3:I, 6wh3:J, 6wh3:K, 6wh3:L, 6wh3:M, 6wh3:N, 6wh3:O, 6wh3:P, 6wh3:Q, 6wh3:R, 6wh3:S, 6wh3:T, 6wh3:U, 6wh3:V, 6wh3:W, 6wh3:X, 6wh3:Y, 6wh3:Z, 6wh3:8, 6wh3:7, 6wh3:6, 6wh3:5, 6wh3:4, 6wh3:3, 6wh3:a, 6wh3:b, 6wh3:c, 6wh3:d, 6wh3:e, 6wh3:f, 6wh3:g, 6wh3:h, 6wh3:i, 6wh3:j, 6wh3:k, 6wh3:l, 6wh3:m, 6wh3:n, 6wh3:o, 6wh3:p, 6wh3:q, 6wh3:r, 6wh3:s, 6wh3:t, 6wh3:u, 6wh3:v, 6wh3:w, 6wh3:x, 6wh3:y, 6wh3:z, 6wh3:1, 6wh3:2
20 5w3f:A 440 50 0.0286 0.0341 0.3000 4.1 4ffb:A, 4u3j:A, 5w3h:A, 5w3j:A
21 5hkh:A 86 66 0.0362 0.2209 0.2879 4.6 5hkh:C
22 1fo4:A 1299 90 0.0476 0.0192 0.2778 6.1 3am9:A, 3am9:B, 3amz:A, 3amz:B, 3b9j:B, 3b9j:C, 3b9j:J, 3b9j:K, 3bdj:A, 3bdj:B, 3etr:B, 3etr:C, 3etr:M, 3etr:N, 3eub:B, 3eub:C, 3eub:K, 3eub:L, 3eub:T, 3eub:U, 3eub:3, 3eub:4, 1fiq:B, 1fo4:B, 8j79:A, 8j79:B, 1n5x:A, 1n5x:B, 3nrz:B, 3nrz:C, 3nrz:K, 3nrz:L, 3ns1:B, 3ns1:C, 3ns1:K, 3ns1:L, 3nvv:B, 3nvv:C, 3nvv:K, 3nvv:L, 3nvw:B, 3nvw:C, 3nvw:K, 3nvw:L, 3nvy:B, 3nvy:C, 3nvy:K, 3nvy:L, 3nvz:B, 3nvz:C, 3nvz:K, 3nvz:L, 3sr6:B, 3sr6:C, 3sr6:K, 3sr6:L, 3una:A, 3una:B, 3unc:A, 3unc:B, 3uni:A, 3uni:B, 1v97:A, 1v97:B, 1vdv:A, 1vdv:B
23 6ywe:L 192 38 0.0229 0.0625 0.3158 7.2 6yws:L, 6ywv:L, 6ywx:L, 6ywy:L
24 3ax7:A 1225 90 0.0476 0.0204 0.2778 7.6 3ax7:B, 3ax9:A, 3ax9:B
25 7wx5:A 288 30 0.0229 0.0417 0.4000 9.3 7wx6:A, 7wx7:A
26 7ym0:A 301 101 0.0514 0.0897 0.2673 9.3 7ym0:B, 7ymr:A, 7ymr:B, 7ymr:C, 7ymr:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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