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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TRPNHTIYINNLNEKIKKDELKKSLHAIFSRFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQ
YAKTDSDIIAKMKGTFV

The query sequence (length=97) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4pkd:B 240 97 0.9794 0.3958 0.9794 2.18e-65 1aud:A, 7b0y:c, 3bo2:A, 3bo3:A, 3bo4:A, 4c4w:A, 4c4w:E, 3cul:A, 3cul:B, 3cun:A, 3cun:B, 7d7v:C, 5ddo:G, 5ddo:C, 5ddp:D, 5ddp:C, 5ddq:D, 5ddq:C, 5ddr:D, 5ddr:C, 7dlz:A, 7dlz:B, 1drz:A, 7dwh:A, 7dwh:B, 1dz5:A, 1dz5:B, 3egz:A, 5fj4:A, 5fj4:E, 3g8s:A, 3g8s:B, 3g8s:C, 3g8s:D, 3g8t:A, 3g8t:B, 3g8t:C, 3g8t:D, 3g96:A, 3g96:B, 3g96:C, 3g96:D, 3g9c:A, 3g9c:B, 3g9c:C, 3g9c:D, 8gxb:C, 8gxb:D, 8gxb:F, 8gxc:C, 8gxc:D, 8gxc:F, 3hhn:B, 3hhn:D, 3iin:A, 3irw:P, 3iwn:C, 3iwn:D, 8jy0:A, 8jy0:C, 8jy0:E, 3k0j:A, 3k0j:B, 3l3c:A, 3l3c:B, 3l3c:C, 3l3c:D, 6las:E, 6las:D, 6las:C, 6lau:E, 6lau:D, 6lau:C, 6lax:D, 6lax:E, 6lax:C, 6laz:D, 6laz:E, 6laz:C, 1m5k:C, 1m5k:F, 1m5o:C, 1m5o:F, 1m5p:C, 1m5p:F, 1m5v:C, 1m5v:F, 3mum:P, 3mur:P, 3mut:P, 3muv:P, 3mxh:P, 2nz4:A, 2nz4:B, 2nz4:C, 2nz4:D, 2oih:A, 2oj3:A, 3p49:B, 4pr6:A, 4prf:A, 7qr3:A, 7qr3:B, 7qr4:A, 6qx9:1A, 3r1h:A, 3r1h:D, 3r1l:A, 3r1l:D, 1sj3:P, 1sj4:P, 1sjf:A, 6sqn:A, 6sqn:B, 6sqn:C, 6sqq:AAA, 6sqq:BBB, 6sqq:CCC, 1u6b:A, 3ucu:P, 3ucz:P, 3ud3:P, 3ud4:P, 1urn:A, 1urn:B, 1urn:C, 1vbx:A, 1vby:A, 1vbz:A, 1vc0:A, 1vc5:A, 1vc6:A, 7vpx:M, 4w90:B, 4w92:B, 1zzn:A
2 6xh2:A 93 88 0.8144 0.8495 0.8977 5.76e-54 6cmn:A, 3k0j:D, 3k0j:C, 6xh0:A, 6xh1:A, 6xh3:A
3 7abg:B 169 91 0.7010 0.4024 0.7473 1.96e-49 7a5p:X, 1a9n:B, 1a9n:D, 7abi:B, 6ah0:p, 6ahd:p, 8c6j:Y, 8ch6:s, 7evo:G, 9fmd:p, 8h6e:2C, 8h6j:2C, 8h6k:2C, 8h6l:2C, 8hk1:G, 8i0p:p, 8i0r:p, 8i0s:p, 8i0t:p, 8i0u:p, 8i0v:p, 8i0w:p, 6icz:p, 6id0:p, 6id1:p, 5mqf:X, 6qdv:Y, 8qo9:2B, 6qx9:2B, 8qxd:2B, 8qzs:2B, 8r08:2B, 8r09:2B, 8r0a:2B, 8r0b:2B, 8rm5:2B, 7vpx:G, 7w59:p, 7w5a:p, 7w5b:p, 5xjc:p, 6y53:b, 6y5q:b, 5yzg:p, 5z56:p, 5z57:p, 5z58:p
4 7abg:B 169 83 0.2680 0.1538 0.3133 0.59 7a5p:X, 1a9n:B, 1a9n:D, 7abi:B, 6ah0:p, 6ahd:p, 8c6j:Y, 8ch6:s, 7evo:G, 9fmd:p, 8h6e:2C, 8h6j:2C, 8h6k:2C, 8h6l:2C, 8hk1:G, 8i0p:p, 8i0r:p, 8i0s:p, 8i0t:p, 8i0u:p, 8i0v:p, 8i0w:p, 6icz:p, 6id0:p, 6id1:p, 5mqf:X, 6qdv:Y, 8qo9:2B, 6qx9:2B, 8qxd:2B, 8qzs:2B, 8r08:2B, 8r09:2B, 8r0a:2B, 8r0b:2B, 8rm5:2B, 7vpx:G, 7w59:p, 7w5a:p, 7w5b:p, 5xjc:p, 6y53:b, 6y5q:b, 5yzg:p, 5z56:p, 5z57:p, 5z58:p
5 6f4h:C 96 90 0.7320 0.7396 0.7889 1.96e-43 6f4g:B, 6f4g:E, 6f4h:A, 6f4h:E
6 8ro1:p 76 76 0.5464 0.6974 0.6974 1.43e-38
7 3jb9:k 89 87 0.3918 0.4270 0.4368 3.87e-24
8 7b9v:Y 88 89 0.2887 0.3182 0.3146 1.75e-14 6bk8:r, 7dco:p, 6exn:Y, 6g90:Y, 5gmk:a, 6j6g:a, 6j6h:a, 6j6n:a, 6j6q:a, 5lj3:Y, 5lj5:Y, 5mq0:Y, 5nrl:Y, 7oqb:Y, 7oqe:Y, 5wsg:X, 5y88:p, 5ylz:p, 5zwm:p, 5zwo:p
9 3lqv:B 115 67 0.2371 0.2000 0.3433 2.67e-08 2f9j:B, 3lqv:A, 7q4o:F, 8qo9:B6, 8qxd:B6, 8qzs:B6, 8r08:B6, 8r09:B6, 8r0a:B6, 8r0b:B6, 8rm5:B6
10 2mb0:B 95 84 0.2680 0.2737 0.3095 9.29e-08
11 2fy1:A 108 82 0.2680 0.2407 0.3171 1.07e-07
12 7q33:A 93 86 0.2371 0.2473 0.2674 1.61e-06 6pai:D, 6q0r:D, 6q0v:D, 6q0w:D, 6sj7:C, 6ud7:C, 6ue5:C
13 2leb:A 101 81 0.2165 0.2079 0.2593 8.04e-06 2lec:A
14 7zew:A 117 80 0.2680 0.2222 0.3250 8.77e-06 7zex:A
15 5mqf:o 223 85 0.2784 0.1211 0.3176 2.01e-05 6id1:y, 7w59:y, 7w5a:y, 7w5b:y
16 7qde:B 169 65 0.2062 0.1183 0.3077 1.01e-04 7qdd:B
17 8y6o:W 167 71 0.2371 0.1377 0.3239 2.30e-04
18 4f02:A 175 86 0.2680 0.1486 0.3023 4.23e-04 1cvj:A, 1cvj:B, 1cvj:C, 1cvj:D, 1cvj:E, 1cvj:F, 1cvj:G, 1cvj:H, 4f02:D
19 4ed5:B 169 66 0.2268 0.1302 0.3333 4.30e-04 4ed5:A
20 8xxm:3G 84 83 0.2268 0.2619 0.2651 4.60e-04 5k0y:O, 8pj1:o, 8pj2:o, 8pj3:o, 8pj4:o, 8pj5:o, 8pj6:o
21 5ith:A 80 83 0.2474 0.3000 0.2892 5.18e-04 5o3j:A
22 2rra:A 99 66 0.1959 0.1919 0.2879 6.80e-04 2kxn:B
23 2n7c:A 89 74 0.1753 0.1910 0.2297 0.001
24 7s7b:C 79 80 0.2062 0.2532 0.2500 0.002 7s7b:G, 7s7c:C
25 8h6e:4R 106 77 0.2371 0.2170 0.2987 0.003 8h6j:4R, 8qp8:R, 8qp9:R, 8qpk:R, 6qw6:R, 6qx9:R, 8qxd:R, 8r08:R, 8r0a:R
26 6dg0:B 84 82 0.2577 0.2976 0.3049 0.004 6dg0:A
27 8i0v:4 161 80 0.2371 0.1429 0.2875 0.004
28 8i0v:4 161 86 0.2165 0.1304 0.2442 0.012
29 7csz:A 175 68 0.2577 0.1429 0.3676 0.005
30 6g90:B 193 70 0.2268 0.1140 0.3143 0.012
31 2yka:A 124 84 0.2165 0.1694 0.2500 0.013
32 4a8x:A 88 67 0.2165 0.2386 0.3134 0.014
33 8pj1:1 588 53 0.1649 0.0272 0.3019 0.017 6fec:w, 2krb:A, 8oz0:I, 8pj2:1, 8pj3:1, 8pj5:1, 8pj6:1
34 4lmz:A 176 64 0.1959 0.1080 0.2969 0.017 3nmr:A, 3nna:A, 3nnc:A, 3nnh:A, 3nnh:C, 3nnh:B, 3nnh:D
35 8xxn:3B 536 53 0.1649 0.0299 0.3019 0.021 6zon:B, 6zp4:B, 6zvj:B
36 6n7p:A 186 70 0.2268 0.1183 0.3143 0.024 6n7r:A, 6n7x:A, 7oqc:B, 7oqe:B, 8w2o:A, 5zwn:Q
37 2mgz:B 105 46 0.1753 0.1619 0.3696 0.027 4ch1:A, 4cio:A, 2ru3:A
38 1fje:B 175 81 0.2577 0.1429 0.3086 0.036 1rkj:A
39 4qqb:A 169 77 0.1959 0.1124 0.2468 0.084 1b7f:A, 1b7f:B, 4qqb:B
40 2adb:A 127 64 0.2165 0.1654 0.3281 0.097 3zzy:A, 3zzy:B, 3zzz:A, 3zzz:B
41 4bs2:A 174 50 0.1340 0.0747 0.2600 0.12 4iuf:A, 4y00:A, 4y00:B, 4y00:C, 4y00:D, 4y0f:A, 4y0f:B
42 6g90:A 99 52 0.1753 0.1717 0.3269 0.23
43 2mxy:A 105 66 0.2165 0.2000 0.3182 0.26 2mz1:A
44 8pv1:CI 152 68 0.2165 0.1382 0.3088 0.32 8i9p:CI, 8i9r:CI, 8i9t:CI, 8i9v:CI, 8i9w:CI, 8i9x:CI, 8i9y:CI, 8i9z:CI, 8ia0:CI, 8pv3:CI, 8pv4:CI, 8pv7:CI, 8pvk:CI
45 8ch6:V 285 84 0.2371 0.0807 0.2738 0.37 7qtt:V
46 2n82:B 104 46 0.1443 0.1346 0.3043 0.48 2err:A, 7vrl:B
47 8esq:o 137 67 0.1753 0.1241 0.2537 0.49 8esr:o, 8etg:o, 8eth:o, 8eti:o, 8eup:o, 8euy:o, 8ev3:o
48 8i0s:Y 320 85 0.2268 0.0688 0.2588 1.3 8i0t:Y, 8i0u:Y, 8i0v:Y
49 3s1s:A 870 52 0.1546 0.0172 0.2885 1.7
50 4bg4:A 356 47 0.1546 0.0421 0.3191 2.0 4bg4:B, 4bhl:A
51 3d34:B 215 27 0.1031 0.0465 0.3704 2.2 3d34:A
52 3zxk:A 530 32 0.1134 0.0208 0.3438 3.2 3zxk:B
53 3ex7:C 392 52 0.1443 0.0357 0.2692 5.1 8c6j:7, 3ex7:H, 9fmd:7, 2hyi:C, 2hyi:I, 8i0w:u, 6icz:u, 2j0q:A, 2j0q:B, 2j0s:A, 2j0u:A, 6qdv:7, 2xb2:A, 2xb2:X, 5xjc:u, 5yzg:u, 7znj:A, 7znj:a, 7znj:F, 7znj:f, 7znj:K, 7znj:k
54 3cei:A 213 29 0.1340 0.0610 0.4483 5.3 3cei:B
55 4dtf:A 356 29 0.1134 0.0309 0.3793 5.6 4dth:A, 4dtl:A, 4e1c:A, 4e1d:A, 4e1f:A, 4gqk:A
56 6n7r:C 133 20 0.1031 0.0752 0.5000 5.8 6n7p:C, 6n7x:C, 7oqc:A, 7oqe:A, 8w2o:C, 5zwn:S
57 4zcf:C 627 82 0.1856 0.0287 0.2195 6.9
58 1gud:A 288 18 0.1134 0.0382 0.6111 7.9 1rpj:A, 8wl7:A, 8wl9:A, 8wlb:A
59 3qdq:A 447 74 0.1959 0.0425 0.2568 8.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218