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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TRLRIAIQKSGRLSKESIELLSECGVKMHSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLG
ENPSYKLLKKLDFGYCRLSLALPQEFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDL
VSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVER
PTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK

The query sequence (length=289) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4yb6:A 296 295 1.0000 0.9764 0.9797 0.0 5ub9:A, 5ub9:B, 5ubg:A, 5ubg:B, 5ubh:A, 5ubh:B, 5ubi:A, 5ubi:B, 4yb5:A, 4yb5:E, 4yb5:B, 4yb5:C, 4yb5:F, 4yb5:D, 4yb6:E, 4yb6:B, 4yb6:C, 4yb6:F, 4yb6:D, 4yb7:B, 4yb7:C, 4yb7:D, 4yb7:E, 4yb7:I, 4yb7:K, 4yb7:A, 4yb7:F, 4yb7:G, 4yb7:H, 4yb7:J, 4yb7:L
2 1h3d:A 288 295 0.6644 0.6667 0.6508 3.36e-136 1q1k:A
3 7dah:C 288 294 0.6228 0.6250 0.6122 2.80e-124 7dah:F
4 2vd3:A 289 295 0.3426 0.3426 0.3356 5.07e-47 2vd3:B
5 5lht:A 284 289 0.3010 0.3063 0.3010 4.78e-29 5lhu:A, 1nh8:A, 5u99:A
6 6czm:E 342 320 0.3253 0.2749 0.2938 5.58e-29 6czm:A, 6czm:C, 6czm:D
7 6czm:F 315 311 0.3010 0.2762 0.2797 1.18e-20 6czm:B
8 1z7n:F 205 194 0.2076 0.2927 0.3093 1.52e-19 1z7m:G, 1z7m:E, 1z7m:H, 1z7n:E, 1z7n:G, 1z7n:H
9 6fca:A 209 213 0.2318 0.3206 0.3146 1.69e-16 6fct:A, 6fcw:A, 6fcy:A, 6fd9:A, 6ftt:E, 6ftt:H, 6ftt:G, 6ftt:F, 6fu2:C, 6fu2:D, 6fu7:C, 6fu7:D, 6fua:C, 6fua:D, 6r02:E, 6r02:F, 6r02:G, 6r02:H, 7z6r:C, 7z6r:D, 7z8u:A
10 1usy:G 203 201 0.2042 0.2906 0.2935 6.38e-15 1usy:F, 1usy:E, 1usy:H
11 6wzg:R 379 58 0.0657 0.0501 0.3276 0.046 7d3s:R, 6wi9:R
12 5zku:F 443 45 0.0484 0.0316 0.3111 0.93 5zku:A, 5zku:B, 5zku:C, 5zku:D, 5zku:E, 5zkw:A, 5zkw:B, 5zkw:C, 5zkw:E, 5zkw:F, 5zl4:A, 5zla:A, 5zla:D, 5zla:B, 5zla:C, 5zla:F, 5zla:E
13 3nhi:A 295 86 0.1003 0.0983 0.3372 1.8 3nht:A
14 6qxp:E 344 85 0.0796 0.0669 0.2706 2.0
15 3cg3:A 315 69 0.0657 0.0603 0.2754 2.5
16 6hxi:B 616 41 0.0519 0.0244 0.3659 3.0 6hxi:D, 6znw:B
17 4ipn:E 463 33 0.0450 0.0281 0.3939 3.0 4ipn:B
18 7r5v:N 297 61 0.0519 0.0505 0.2459 3.2 7yyh:N
19 5c56:A 528 118 0.0900 0.0492 0.2203 3.8 5c6d:A, 5c6d:B, 5gg4:A, 5gg4:B, 5gg4:C, 5gg4:D, 6p5l:A, 4wph:B, 4wph:A, 4wpi:B, 4wpi:A, 7xpy:A, 4z96:A, 4z97:A
20 2xma:E 141 44 0.0519 0.1064 0.3409 4.8 2xm3:A, 2xm3:B, 2xm3:C, 2xm3:D, 2xm3:F, 2xm3:E, 2xma:A, 2xma:B, 2xma:F, 2xo6:A, 2xo6:D, 2xqc:A, 2xqc:D
21 7fcm:B 269 40 0.0484 0.0520 0.3500 6.6 7f44:A, 7fcm:A
22 8qqk:B 263 35 0.0415 0.0456 0.3429 6.7 1cyx:A, 1fft:B, 8go3:B, 7n9z:G, 6wti:B, 7xmc:B, 7xmd:B
23 6emu:A 170 56 0.0727 0.1235 0.3750 7.2 6emu:B, 6emu:C, 6emv:A, 6emv:B, 6emv:C
24 7fc8:A 243 40 0.0484 0.0576 0.3500 7.2
25 4b98:A 441 20 0.0311 0.0204 0.4500 9.6 4b98:B, 4b98:C, 4b98:D, 4b9b:A, 4b9b:B, 4b9b:C, 4b9b:D, 4b9b:E, 4b9b:F, 4b9b:G, 4b9b:H, 4bq0:A, 4bq0:B, 4bq0:C, 4bq0:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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