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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TRKAVIGYYFIPTNQINNYTETDTSVVPFPVSNITPAKAKQLTHINFSFLDINSNLECAWDPATNDAKARDVVNRLTALK
AHNPSLRIMFSIGGWYYSNDLGVSHANYVNAVKTPASRAKFAQSCVRIMKDYGFDGVDINWEYPQAAEVDGFIAALQEIR
TLLNQQTITDGRQALPYQLTIAGAGGAFFLSRYYSKLAQIVAPLDYINLMTYDLAGPWEKVTNHQAALFGDAAGPTFYNA
LREANLGWSWEELTRAFPSPFSLTVDAAVQQHLMMEGVPSAKIVMGVPFYGRAFKGVSGGNGGQYSSHSTPGEDPYPSTD
YWLVGCEECVRDKDPRIASYRQLEQMLQGNYGYQRLWNDKTKTPYLYHAQNGLFVTYDDAESFKYKAKYIKQQQLGGVMF
WHLGQDNRNGDLLAALDRYFNAADYDDSQLDMGTGLRYTGVGPGNLPIMTAPAYVPGTTYAQGALVSYQGYVWQTKWGYI
TSAPGSDSAWLKVGRVA

The query sequence (length=497) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1e6z:B 498 497 0.9980 0.9960 0.9980 0.0 7c34:A, 7c34:B, 7c92:A, 7c92:B, 7cb1:A, 7cb1:B, 1e6r:A, 1e6r:B, 1e6z:A, 1h0g:B, 1h0g:A, 1h0i:A, 1h0i:B, 6jk9:A, 6jk9:B, 6jkf:A, 6jkf:B, 1o6i:A, 1o6i:B, 1ogg:A, 1ogg:B, 1ur8:A, 1ur8:B, 1ur9:A, 1ur9:B, 1w1p:A, 1w1p:B, 1w1t:A, 1w1t:B, 1w1v:A, 1w1v:B, 1w1y:A, 1w1y:B, 3wd1:A, 3wd2:A, 3wd3:A, 3wd4:A, 4z2g:A, 4z2h:A, 4z2i:A, 4z2j:A, 4z2k:A, 4z2l:A
2 6bt9:B 626 348 0.2535 0.2013 0.3621 3.52e-56 6bt9:A
3 6kst:B 372 385 0.2334 0.3118 0.3013 1.58e-51 6kxl:A, 6kxl:B, 6kxm:A, 6kxm:B, 6kxn:A, 6kxn:B
4 3g6m:A 388 426 0.2696 0.3454 0.3146 3.16e-44
5 8c6z:A 573 411 0.2394 0.2077 0.2895 1.49e-43 8ovr:A
6 5nr8:A 377 376 0.2213 0.2918 0.2926 2.40e-40 1hki:A, 1hkj:A, 1hkk:A, 1hkm:A, 6jjr:A, 6jk6:A, 5nra:A, 5nrf:A, 1waw:A, 1wb0:A, 6ze8:A, 6ze8:B, 6ze8:C, 6ze8:D, 6ze8:E, 6ze8:F
7 7akq:A 389 430 0.2535 0.3239 0.2930 6.25e-38 6epb:A, 6ylj:A, 6yn4:A
8 1ll4:A 392 400 0.2294 0.2908 0.2850 1.02e-35 1ll4:B, 1ll4:C, 1ll4:D
9 2a3c:A 395 390 0.2233 0.2810 0.2846 4.45e-34 2a3a:A, 2a3a:B, 2a3b:A, 2a3b:B, 2a3c:B, 2a3e:A, 2a3e:B, 3ch9:A, 3ch9:B, 3chc:A, 3chc:B, 3chd:A, 3chd:B, 3che:A, 3che:B, 3chf:A, 3chf:B, 2iuz:A, 2iuz:B, 1w9u:A, 1w9u:B, 1w9v:A, 1w9v:B
10 2aos:A 361 398 0.2193 0.3019 0.2739 1.84e-33 2fdm:A, 4mav:A, 4ml4:A, 4nsb:A, 2olh:A, 4q7n:A, 5z05:A, 5z3s:A, 5z4w:A, 1zbc:A, 1zbk:A, 1zbv:A, 1zbw:A, 1zl1:A
11 6le7:A 381 372 0.2012 0.2625 0.2688 3.70e-33 6le8:A
12 8r42:B 362 405 0.2193 0.3011 0.2691 2.36e-32 8r41:A, 8r41:B, 8r42:A, 8r4x:A, 8r4x:B, 8r4x:C, 8r4x:D
13 3wqv:A 383 377 0.1992 0.2585 0.2626 1.47e-31 3wqw:A
14 6jmb:A 374 388 0.2153 0.2861 0.2758 3.19e-31
15 8fr9:B 374 404 0.2093 0.2781 0.2574 3.01e-29 8frb:D
16 1ffq:A 540 433 0.2475 0.2278 0.2841 9.89e-29 7fd6:A, 2wk2:A, 2wly:A, 2wlz:A, 2wm0:A, 1x6n:A
17 6jav:A 377 342 0.2012 0.2653 0.2924 1.14e-28 6jaw:A, 6jax:A, 6jay:A
18 3arq:A 575 364 0.2093 0.1809 0.2857 4.35e-28 3arp:A, 3arr:A, 3art:A, 3aru:A, 3arv:A, 3arw:A, 3arx:A, 3ary:A, 3arz:A, 3as0:A, 3as1:A, 3as2:A, 3as3:A, 8hrf:A, 8hrf:B
19 1e9l:A 372 390 0.2012 0.2688 0.2564 5.06e-28
20 3fy1:A 377 376 0.2032 0.2679 0.2686 5.90e-28 3fy1:B, 3rm4:A, 3rm4:B, 3rm8:A, 3rm8:B, 3rm9:A, 3rm9:B, 3rme:A, 3rme:B, 2ybt:A, 2ybt:B, 2ybt:C, 2ybt:D, 2ybt:E, 2ybt:F, 2ybu:A, 2ybu:B, 2ybu:C, 2ybu:D, 2ybu:E, 2ybu:F
21 7vrg:A 540 357 0.2052 0.1889 0.2857 1.80e-27 5gqb:A, 6jmn:A, 7vrg:B
22 8ose:A 563 425 0.2133 0.1883 0.2494 2.59e-27 8owf:A
23 4r5e:A 343 396 0.1911 0.2770 0.2399 2.81e-27
24 6t9m:AAA 350 415 0.2093 0.2971 0.2506 9.68e-26
25 6hm1:A 386 413 0.2193 0.2824 0.2639 5.90e-25
26 8hw8:A 326 401 0.2113 0.3221 0.2618 9.48e-25
27 5df0:A 528 364 0.2072 0.1951 0.2830 1.24e-24 5df0:B
28 1jne:A 400 354 0.1871 0.2325 0.2627 9.08e-17
29 3co4:A 311 258 0.1207 0.1929 0.2326 2.09e-05
30 3co4:A 311 29 0.0302 0.0482 0.5172 3.8
31 4wiw:D 349 253 0.1147 0.1633 0.2253 7.69e-04 4wiw:A, 4wiw:B, 4wiw:C, 4wiw:E, 4wiw:F
32 5jh8:A 317 306 0.1408 0.2208 0.2288 0.12
33 4m8l:A 220 143 0.0704 0.1591 0.2448 0.30 3kwm:D, 4m8l:B, 4m8l:D, 4m8l:C
34 6ve1:C 268 132 0.0664 0.1231 0.2500 0.61 1c8y:A, 6ve1:B, 6ve1:D
35 8aan:A 228 44 0.0362 0.0789 0.4091 0.74 8ac8:A, 8ac8:C, 8d86:C, 8d8m:C, 1rep:C, 7rva:C, 7sdp:C, 7sgc:C, 7soz:C, 7spm:C, 8tip:C, 8tiq:C, 8tir:C, 8tis:C, 8tit:C, 8tiu:C, 8tiv:C, 8tiw:C, 8tix:C, 8tiy:C, 8tiz:C, 8tj0:C, 8tj1:C, 7u6k:C, 7u7o:C, 7ufx:C, 7uog:C, 7ur0:C, 7uv6:C, 7uv7:C, 7uxy:C, 2z9o:A, 2z9o:B
36 5kz6:A 327 72 0.0362 0.0550 0.2500 1.2 3n13:A, 3n15:A, 3n17:A, 3n18:A, 3n1a:A
37 3vlm:A 663 139 0.0664 0.0498 0.2374 2.0 3vlm:B
38 4y60:C 76 39 0.0282 0.1842 0.3590 2.3
39 1itk:B 714 139 0.0664 0.0462 0.2374 2.8 1itk:A, 3uw8:A, 3uw8:B, 3vlh:A, 3vlh:B, 3vli:A, 3vli:B, 3vlj:A, 3vlj:B, 3vlk:A, 3vlk:B, 3vll:A, 3vll:B
40 4tx8:A 374 166 0.0785 0.1043 0.2349 3.6
41 6kpm:A 295 29 0.0241 0.0407 0.4138 6.1 6kpn:A, 6kpo:A
42 4axn:A 316 23 0.0201 0.0316 0.4348 9.8 4axn:B
43 6ldo:A 381 85 0.0503 0.0656 0.2941 9.8 6ldo:B, 6ldo:C, 6ldo:D, 6ldo:E, 6ldo:F, 6le4:A, 6le4:B, 6le4:C, 6le4:D, 6le4:E, 6le4:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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