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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TQTQTQPAGNAFQYEIRDISLAEFGRKEINLAEHEMPGLMQTREKYGAEQPLKGVRLAGSLHMTIQTAVLIETLQALGAN
VRWCSCNIFSTQDHAAAAIVAAGTPVFAWKGETLEEYWECTWKTLLFPDDMGPQLIVDDGGDATLMVHRGFYAEDNPSIL
DDDEGSEELAIVNKLLKRIQKEKPGYWHKIVPELKGVSEETTTGVHRLYEMMKEGKLLFPALNVNDSVTKSKFDNVYGCR
HSLVDAIMRATDVMLSGKVACVLGYGDVGKGSAESLKGQGARVVVTEVDPICALQACMAGYEVVRIEDVLDKAEIFVTTT
GNCDIIRIEHMEKMRHNAIVCNIGHFDNEIQVKALKEFPGIKRIEIKPQVDQFVFPDGHAIVLLAEGRLVNLGCATGHPS
FVMSNSFTNQTLAQISLWKEKYELGVYTLPKKLDEEVARLHLEKLGAKLTVLTDKQAKYLGIAKDGPYKPDHYRY

The query sequence (length=475) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6uk3:A 475 475 1.0000 1.0000 1.0000 0.0 6uk3:C, 6uk3:B, 6uk3:D
2 5v96:A 467 464 0.7179 0.7302 0.7349 0.0 5v96:B, 5v96:C, 5v96:D
3 5m5k:C 471 467 0.6547 0.6603 0.6660 0.0 6exi:A, 6exi:B, 6exi:C, 6exi:D, 4lvc:A, 4lvc:B, 4lvc:C, 4lvc:D, 5m5k:A, 5m5k:B, 5m5k:D, 5m65:A, 5m65:B, 5m66:A, 5m66:B, 5m66:C, 5m66:D, 5m67:A, 5m67:B, 5m67:C, 5m67:D
4 3d64:A 462 465 0.6211 0.6385 0.6344 0.0 3d64:B, 3glq:A, 3glq:B
5 3ond:B 488 473 0.6337 0.6168 0.6364 0.0 3ond:A, 3one:A, 3one:B, 3onf:A, 3onf:B
6 3n58:B 461 462 0.6084 0.6269 0.6255 0.0 3n58:A, 3n58:C, 3n58:D
7 3ce6:A 486 481 0.5937 0.5802 0.5863 0.0 3ce6:B, 3ce6:C, 3ce6:D, 3dhy:A, 3dhy:B, 3dhy:C, 3dhy:D, 2ziz:A, 2ziz:B, 2ziz:C, 2ziz:D, 2zj0:A, 2zj0:B, 2zj0:C, 2zj0:D, 2zj1:A, 2zj1:B, 2zj1:C, 2zj1:D
8 3h9u:C 435 471 0.6084 0.6644 0.6136 0.0 3h9u:A, 3h9u:B, 3h9u:D
9 1v8b:A 476 475 0.5621 0.5609 0.5621 0.0 1v8b:B, 1v8b:C, 1v8b:D
10 6aph:A 432 465 0.5979 0.6574 0.6108 0.0
11 1a7a:A 431 465 0.5789 0.6381 0.5914 0.0 1a7a:B, 5axa:A, 5axa:C, 5axb:A, 5axb:C, 5axc:A, 5axc:C, 5axd:A, 5axd:C, 1b3r:A, 1b3r:B, 1b3r:C, 1b3r:D, 8cod:A, 8cod:B, 1d4f:A, 1d4f:B, 1d4f:C, 1d4f:D, 2h5l:A, 2h5l:B, 2h5l:C, 2h5l:D, 2h5l:E, 2h5l:F, 2h5l:G, 2h5l:H, 1k0u:A, 1k0u:B, 1k0u:C, 1k0u:D, 1k0u:E, 1k0u:F, 1k0u:G, 1k0u:H, 1ky4:A, 1ky4:B, 1ky4:C, 1ky4:D, 1ky5:A, 1ky5:B, 1ky5:C, 1ky5:D, 1li4:A, 3nj4:A, 3nj4:B, 3nj4:C, 3nj4:D, 4pfj:A, 4pfj:B, 4pgf:A, 4pgf:B, 5w49:A, 5w49:B, 5w4b:A, 5w4b:B, 5w4b:C, 5w4b:D, 5w4b:E, 5w4b:F, 1xwf:A, 1xwf:B, 1xwf:C, 1xwf:D, 4yvf:A, 4yvf:B
12 5jpi:A 496 496 0.5642 0.5403 0.5403 0.0 5hm8:A, 5hm8:B, 5hm8:C, 5hm8:D, 5hm8:E, 5hm8:F, 5hm8:G, 5hm8:H, 5jpi:B, 5jpi:C, 5jpi:D, 5jxw:A, 5jxw:B, 5jxw:C, 5jxw:D, 5t8k:A, 5t8k:C, 5t8k:B, 5t8k:D, 5tj9:A, 5tj9:B, 5tj9:C, 5tj9:D, 5tls:A, 5tls:B, 5tls:C, 5tls:D, 5utu:A, 5utu:B, 5utu:C, 5utu:D, 5utu:E, 5utu:F, 5utu:G, 5utu:H
13 6gbn:B 435 466 0.5621 0.6138 0.5730 0.0 6gbn:A, 6gbn:C, 6gbn:D
14 3g1u:C 424 456 0.5600 0.6274 0.5833 7.70e-175 3g1u:A, 3g1u:B, 3g1u:D
15 8cfu:A 467 504 0.5347 0.5439 0.5040 3.22e-151 8ajs:AAA, 8ajs:DDD, 8ajs:BBB, 8ajs:CCC, 8ajt:AAA, 8ajt:DDD, 8ajt:BBB, 8ajt:CCC, 8aju:AAA, 8aju:CCC, 8ajv:AAA, 8ajv:DDD, 8ajv:BBB, 8ajv:CCC, 8ajv:FFF, 8ajv:III, 8ajv:GGG, 8ajv:HHH, 8ajw:AAA, 8ajw:DDD, 8ajw:BBB, 8ajw:CCC, 8azf:A, 8azf:C, 8cfb:A, 8cfb:D, 8cfb:B, 8cfb:C, 8cfc:A, 8cfc:D, 8cfc:B, 8cfc:C, 8cfd:A, 8cfd:D, 8cfd:B, 8cfd:C, 8cfe:A, 8cfe:D, 8cfe:B, 8cfe:C, 8cfg:A, 8cfg:D, 8cfg:B, 8cfg:C, 8cfh:A, 8cfh:D, 8cfh:B, 8cfh:C, 8cfi:A, 8cfi:D, 8cfi:B, 8cfi:C, 8cfj:A, 8cfj:D, 8cfj:B, 8cfj:C, 8cfk:A, 8cfk:D, 8cfk:B, 8cfk:C, 8cfl:A, 8cfl:D, 8cfl:B, 8cfl:C, 8cfm:A, 8cfm:D, 8cfm:B, 8cfm:C, 8cfn:A, 8cfn:C, 8cfo:A, 8cfo:D, 8cfo:B, 8cfo:C, 8cfp:A, 8cfp:D, 8cfp:B, 8cfp:C, 8cfq:A, 8cfq:D, 8cfq:B, 8cfq:C, 8cfr:A, 8cfr:D, 8cfr:B, 8cfr:C, 8cfs:A, 8cfs:D, 8cfs:B, 8cfs:C, 8cft:A, 8cft:D, 8cft:B, 8cft:C, 8cfu:D, 8cfu:B, 8cfu:C, 8cfv:A, 8cfv:D, 8cfv:B, 8cfv:C, 8cfw:A, 8cfw:D, 8cfw:B, 8cfw:C, 8cfx:A, 8cfx:D, 8cfx:B, 8cfx:C, 8cfx:G, 8cfx:J, 8cfx:H, 8cfx:I, 8cfy:A, 8cfy:D, 8cfy:B, 8cfy:C, 8cfy:G, 8cfy:J, 8cfy:H, 8cfy:I, 8cfz:A, 8cfz:D, 8cfz:B, 8cfz:C, 8cfz:H, 8cfz:K, 8cfz:I, 8cfz:J, 8cg0:A, 8cg0:D, 8cg0:B, 8cg0:C, 8cg1:A, 8cg1:D, 8cg1:B, 8cg1:C, 8cg1:G, 8cg1:J, 8cg1:H, 8cg1:I, 8cg2:A, 8cg2:C, 6f3m:A, 6f3m:B, 6f3m:C, 6f3m:D, 6f3n:A, 6f3n:B, 6f3n:C, 6f3n:D, 6f3o:A, 6f3o:B, 6f3o:C, 6f3o:D, 6f3p:A, 6f3p:C, 6f3q:A, 6f3q:B, 6f3q:C, 6f3q:D, 7zd0:A, 7zd0:D, 7zd0:B, 7zd0:C, 7zd1:A, 7zd1:D, 7zd1:B, 7zd1:C, 7zd2:A, 7zd2:D, 7zd2:B, 7zd2:C, 7zd3:A, 7zd3:D, 7zd3:B, 7zd3:C, 7zd4:A, 7zd4:D, 7zd4:B, 7zd4:C
16 3gvp:A 433 474 0.4505 0.4942 0.4515 2.61e-144 3gvp:B, 3gvp:C, 3gvp:D, 3mtg:A, 3mtg:B
17 7r39:A 412 447 0.3832 0.4417 0.4072 6.48e-108 7r39:B, 7r39:C, 7r39:D, 7r39:E, 7r39:F, 7r39:G, 7r39:H
18 8qno:A 421 452 0.3937 0.4442 0.4137 1.20e-100 8qno:B, 7r37:A, 7r37:B, 7r38:A, 7r38:B
19 7o5l:A 417 452 0.3874 0.4412 0.4071 2.96e-99 7o5l:C, 7o5m:A, 7o5m:C, 7zd7:A, 7zd7:C, 7zd8:A, 7zd8:C, 7zd9:A, 7zd9:C
20 7r3a:A 411 447 0.3726 0.4307 0.3960 1.24e-97 7r3a:B, 7r3a:C, 7r3a:D, 7r3a:E, 7r3a:F, 7r3a:G, 7r3a:H
21 3x2f:A 406 438 0.3495 0.4089 0.3790 1.06e-89 5tov:B, 5tow:B, 3x2e:A, 3x2e:B, 3x2e:C, 3x2e:D, 3x2f:B
22 2wzm:A 274 139 0.0779 0.1350 0.2662 0.001 2wzm:B
23 4zgs:A 346 137 0.0737 0.1012 0.2555 0.010 4zgs:B, 4zgs:C, 4zgs:D, 4zgs:E, 4zgs:F, 4zgs:G, 4zgs:H
24 8ep7:C 328 63 0.0442 0.0640 0.3333 0.014 8ep7:A, 8ep7:B
25 6bii:A 332 166 0.0842 0.1205 0.2410 0.015 6bii:B
26 5aov:A 334 110 0.0611 0.0868 0.2636 0.049
27 4cjx:A 297 119 0.0695 0.1111 0.2773 0.049 4cjx:B
28 4cuk:A 330 113 0.0568 0.0818 0.2389 0.050 4cuk:D
29 1j49:A 332 91 0.0442 0.0633 0.2308 0.29 1j49:B
30 6jcz:C 331 61 0.0379 0.0544 0.2951 0.49 6jcw:A, 6jcw:B, 6jcw:C, 6jcw:D, 6jcw:E, 6jcw:F, 6jcw:G, 6jcw:H, 6jcw:I, 6jcw:J, 6jcw:K, 6jcw:L, 6jcz:A, 6jcz:B, 6jcz:D, 6jcz:E, 6jcz:F, 6jcz:G, 6jcz:H, 6jcz:I, 6jcz:J, 6jcz:K, 6jcz:L, 6jd1:A, 6jd1:B, 6jd1:C, 6jd1:D, 6jd1:E, 6jd1:F, 6jd1:G, 6jd1:H, 6jd1:I, 6jd1:J, 6jd1:K, 6jd1:L, 6jd2:A, 6jd2:B, 6jd2:C, 6jd2:D, 6jd2:E, 6jd2:F, 6jd2:G, 6jd2:H, 6jd2:I, 6jd2:J, 6jd2:K, 6jd2:L, 6kou:A, 6kou:B, 6kou:C, 6kou:D, 6kou:E, 6kou:F, 6kou:G, 6kou:H, 6kou:I, 6kou:J, 6kou:K, 6kou:L, 6kpa:A, 6kpa:B, 6kpa:C, 6kpa:D, 6kpa:E, 6kpa:F, 6kpa:G, 6kpa:H, 6kpa:I, 6kpa:J, 6kpa:K, 6kpa:L, 6kph:A, 6kph:B, 6kph:C, 6kph:D, 6kph:E, 6kph:F, 6kph:G, 6kph:H, 6kph:I, 6kph:J, 6kph:K, 6kph:L, 6kpi:A, 6kpi:B, 6kpi:C, 6kpi:D, 6kpi:E, 6kpi:F, 6kpi:G, 6kpi:H, 6kpi:I, 6kpi:J, 6kpi:K, 6kpi:L, 6kpj:A, 6kpj:B, 6kpj:C, 6kpj:D, 6kpj:E, 6kpj:F, 6kpj:G, 6kpj:H, 6kpj:I, 6kpj:J, 6kpj:K, 6kpj:L, 6kq4:A, 6kq4:B, 6kq4:C, 6kq4:D, 6kq4:E, 6kq4:F, 6kq4:G, 6kq4:H, 6kq4:I, 6kq4:J, 6kq4:K, 6kq4:L, 6kqj:A, 6kqj:B, 6kqj:C, 6kqj:D, 6kqj:E, 6kqj:F, 6kqj:G, 6kqj:H, 6kqj:I, 6kqj:J, 6kqj:K, 6kqj:L, 6kqk:A, 6kqk:B, 6kqk:C, 6kqk:D, 6kqk:E, 6kqk:F, 6kqk:G, 6kqk:H, 6kqk:I, 6kqk:J, 6kqk:K, 6kqk:L, 6kqo:A, 6kqo:B, 6kqo:C, 6kqo:D, 6kqo:E, 6kqo:F, 6kqo:G, 6kqo:H, 6kqo:I, 6kqo:J, 6kqo:K, 6kqo:L
31 6q8n:A 321 116 0.0695 0.1028 0.2845 0.57 6q8n:B
32 8ijg:C 250 131 0.0884 0.1680 0.3206 0.60 8ij6:A, 8ij6:B, 8ij6:C, 8ij6:D, 8ijg:A, 8ijg:B, 8ijg:D
33 3dc2:A 526 92 0.0547 0.0494 0.2826 0.61 3dc2:B, 3ddn:B
34 7q03:A 328 61 0.0463 0.0671 0.3607 0.61 7q07:A
35 1dxy:A 330 92 0.0484 0.0697 0.2500 1.3
36 4wec:A 258 78 0.0484 0.0891 0.2949 1.3 4wec:B, 4wec:C, 4wec:D
37 4xdy:A 331 70 0.0442 0.0634 0.3000 1.4 4xdy:B
38 8rbx:b 1051 69 0.0547 0.0247 0.3768 1.4 7pks:b, 8rbz:b
39 8ir1:J 259 43 0.0274 0.0502 0.3023 1.5 8fl0:NF, 8fl6:NF, 8fl7:NF, 8fl9:NF, 8idy:v, 8ine:s, 8inf:s, 8ir3:J
40 5jo9:A 239 36 0.0358 0.0711 0.4722 1.9
41 1bgv:A 449 48 0.0358 0.0379 0.3542 1.9
42 1zgd:A 308 107 0.0737 0.1136 0.3271 1.9 1zgd:B
43 5mh5:A 308 95 0.0505 0.0779 0.2526 2.0 5mh5:B, 5mh6:A, 5mh6:B, 5mh6:C, 5mh6:D, 5mha:A, 5mha:B
44 6bul:B 327 64 0.0379 0.0550 0.2812 2.5 6aqj:A, 6aqj:B, 6bul:A, 6c55:A, 6c55:B, 6c5n:A, 6c5n:B, 7ke2:B, 7ke2:A, 7kh7:A, 7kh7:B, 6vo2:A, 6vo2:B, 5w3k:A, 5w3k:B
45 2hf8:A 211 67 0.0463 0.1043 0.3284 2.9 2hf8:B, 2hf9:A, 2hf9:B
46 7krm:C 244 40 0.0295 0.0574 0.3500 4.1 7krm:A, 7krm:B, 7krm:D
47 8k32:C 333 32 0.0295 0.0420 0.4375 4.4 8k32:A, 8k32:B, 8k32:D
48 6nje:A 297 53 0.0358 0.0572 0.3208 5.5
49 2fdc:A 505 33 0.0232 0.0218 0.3333 5.7
50 2d7d:A 621 33 0.0232 0.0177 0.3333 5.9 2nmv:A, 3v4r:B, 3v4r:A
51 3iup:A 376 95 0.0589 0.0745 0.2947 6.9 3iup:B
52 4a7x:C 234 45 0.0337 0.0684 0.3556 7.0 4a7w:A, 4a7w:B, 4a7x:B, 4a7x:D, 4a7x:E
53 5yeq:B 329 87 0.0526 0.0760 0.2874 7.1
54 1bw9:A 350 57 0.0463 0.0629 0.3860 9.3 1bw9:B, 1bxg:A, 1bxg:B, 1c1d:A, 1c1d:B, 1c1x:A, 1c1x:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218