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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TQDLKTGGEQGYLRIATEEAFATREIIDVYLRMIRDGTADKGMVSLWGFYAQSPSERATQILERLLDLGERRIADMDATG
IDKAILALTSPGVQPLHDLDEARTLATRANDTLADACQKYPDRFIGMGTVAPQDPEWSAREIHRGARELGFKGIQINSHT
QGRYLDEEFFDPIFRALVEVDQPLYIHPATSPDSMIDPMLEAGLDGAIFGFGVETGMHLLRLITIGIFDKYPSLQIMVGH
MGEALPYWLYRLDYMHQAGVRSQRYERMKPLKKTIEGYLKSNVLVTNSGVAWEPAIKFCQQVMGEDRVMYAMDYPYQYVA
DEVRAMDAMDMSAQTKKKFFQTNAEKWFKL

The query sequence (length=350) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4qrn:A 352 350 1.0000 0.9943 1.0000 0.0 4inf:A, 4inf:B, 4inf:C, 4inf:D, 4qrn:B, 4qrn:C, 4qrn:D, 4qs5:A, 4qs5:B, 4qs5:C, 4qs5:D, 4qs6:A, 4qs6:B, 4qtg:A, 4qtg:B
2 4icm:A 335 337 0.3714 0.3881 0.3858 3.36e-76 4icm:B, 4icm:C, 4icm:D, 4icm:E, 4icm:F, 4icm:G, 4icm:H, 4l6d:A, 4l6d:B, 4l6d:C, 4l6d:D, 4l6d:E, 4l6d:F, 4l6d:G, 4l6d:H, 4ng3:A, 4ng3:B, 4ng3:C, 4ng3:D, 4ng3:E, 4ng3:F, 4ng3:G, 4ng3:H, 4ni8:A, 4ni8:B, 4ni8:C, 4ni8:D, 4ni8:E, 4ni8:F, 4ni8:G, 4ni8:H
3 4qro:A 332 346 0.3343 0.3524 0.3382 2.40e-55 4qro:B, 4qro:C, 4qro:D, 4qro:E, 4qro:F, 4qro:G, 4qro:H
4 2dvt:A 325 308 0.2914 0.3138 0.3312 7.44e-51 2dvt:B, 2dvt:C, 2dvt:D, 2dvu:A, 2dvu:B, 2dvu:C, 2dvu:D, 2dvx:A, 2dvx:B, 2dvx:C, 2dvx:D
5 6m53:B 339 351 0.3029 0.3127 0.3020 1.45e-50 7bp1:A, 7bp1:C, 7bp1:D, 7bpc:A, 7bpc:C, 6m53:A, 6m53:C, 6m53:D
6 7a19:A 339 311 0.2600 0.2684 0.2926 1.87e-49 7a19:B, 7a1a:A, 7a1a:B, 7wjr:A, 7wjr:B, 7wjr:C, 7wjr:D, 7wkl:A, 7wkl:B, 7wkl:C, 7wkl:D, 7wkm:A, 7wkm:B, 7wmb:A, 7wmb:B
7 3nur:A 305 258 0.2371 0.2721 0.3217 6.34e-43
8 8h41:B 357 315 0.2314 0.2269 0.2571 2.53e-33 8h41:A, 6jqw:A, 6jqw:B, 6jqx:A, 6jqx:B
9 4ofc:A 335 280 0.2171 0.2269 0.2714 7.12e-27 4igm:A, 4igm:B, 4igm:C, 4igm:D, 4igm:E, 4igm:F, 4ign:A, 4ign:B, 4ign:C, 4ign:D, 4ign:E, 4ign:F, 4ih3:A, 4ih3:B, 4ih3:C, 4ih3:D, 4ih3:E, 4ih3:F, 4ofc:B, 4ofc:C, 4ofc:D, 4ofc:E, 4ofc:F, 7pwy:A, 7pwy:B, 7pwy:D, 2wm1:A
10 7pwy:C 301 279 0.2171 0.2525 0.2724 1.25e-24
11 4era:A 332 283 0.2171 0.2289 0.2686 3.81e-19 4epk:A, 4epk:B, 4era:B, 4erg:A, 4erg:B, 4eri:A, 4eri:B, 2hbv:A, 2hbv:B, 2hbx:A, 2hbx:B, 4ifk:A, 4ifk:B, 4ifo:A, 4ifo:B, 4ifr:A, 4ifr:B, 4ig2:A, 4ig2:B, 7k12:A, 7k13:A, 7k13:B, 7k13:C, 6mgs:A, 6mgs:B, 6mgs:C, 6mgt:A, 6mgt:B
12 4hjw:C 378 273 0.1971 0.1825 0.2527 8.32e-18 4hjw:A, 4hjw:B
13 3ij6:A 303 291 0.1857 0.2145 0.2234 4.96e-17 3ij6:B, 3ij6:C, 3ij6:D
14 6dxs:A 342 289 0.2029 0.2076 0.2457 3.00e-14 6dwv:B, 6dwv:A, 6dwv:C, 6dwv:D, 6dxq:A, 6dxq:B, 6dxq:C, 6dxq:D, 6dxs:B, 6dxs:C, 6dxs:D
15 4hk5:D 380 245 0.1600 0.1474 0.2286 7.67e-14 4hk5:A, 4hk5:B, 4hk5:C, 4hk6:A, 4hk6:B, 4hk6:C, 4hk6:D, 4hk7:A, 4hk7:B, 4hk7:C, 4hk7:D, 4lak:A, 4lak:B, 4lal:A, 4lal:B, 4lal:C, 4lal:D, 4lam:A, 4lam:B, 4lao:A, 4lao:B
16 8sm7:A 347 285 0.1886 0.1902 0.2316 3.78e-12 8sm7:B, 8sm7:D, 8sm7:G
17 2gwg:A 329 251 0.1800 0.1915 0.2510 5.42e-12 2gwg:B
18 5vn5:C 334 270 0.2000 0.2096 0.2593 5.53e-10 6e6i:A, 6e6i:B, 6e6i:C, 6e6i:D, 6e6i:E, 6e6i:F, 6e6i:G, 6e6i:H, 6e6i:I, 5vn5:A, 5vn5:B
19 8sm8:J 345 268 0.1857 0.1884 0.2425 7.04e-07 8sm8:G, 8sm8:A, 8sm8:D
20 2f6k:A 306 149 0.0971 0.1111 0.2282 2.96e-06 2f6k:B
21 8sm6:D 354 254 0.1686 0.1667 0.2323 9.30e-06 8sm6:A, 8sm6:B, 8sm6:C, 8sma:A, 8sma:B, 8sma:G, 8sma:J
22 8fun:D 370 303 0.1886 0.1784 0.2178 3.83e-04 8ful:B, 8ful:D, 8ful:F, 8ful:H, 8fum:B, 8fum:D, 8fum:F, 8fum:H, 8fun:B, 8fuo:B, 8fuo:D, 6m2i:B
23 8sm9:F 344 136 0.1029 0.1047 0.2647 6.99e-04 8sm9:B, 8sm9:D, 8sm9:H
24 6m1w:B 346 297 0.1800 0.1821 0.2121 0.001
25 3cjp:A 262 79 0.0629 0.0840 0.2785 0.052 3cjp:B
26 6m1w:A 354 296 0.1771 0.1751 0.2095 0.074 8ful:A, 8ful:C, 8ful:E, 8ful:G, 8fum:A, 8fum:C, 8fum:E, 8fum:G, 8fun:A, 8fun:C, 8fuo:A, 8fuo:C, 6m2i:A
27 5ur2:B 959 53 0.0457 0.0167 0.3019 0.66 5ur2:A, 5ur2:C, 5ur2:D
28 5a24:A 222 49 0.0543 0.0856 0.3878 0.72
29 1bxr:A 1073 87 0.0600 0.0196 0.2414 1.1 1a9x:A, 1a9x:C, 1a9x:E, 1a9x:G, 1bxr:C, 1bxr:E, 1bxr:G, 1c30:A, 1c30:C, 1c30:E, 1c30:G, 1c3o:A, 1c3o:C, 1c3o:E, 1c3o:G, 1ce8:A, 1ce8:C, 1ce8:E, 1ce8:G, 1cs0:A, 1cs0:C, 1cs0:E, 1cs0:G, 1jdb:B, 1jdb:E, 1jdb:H, 1jdb:K, 1kee:A, 1kee:C, 1kee:E, 1kee:G, 1m6v:A, 1m6v:C, 1m6v:E, 1m6v:G, 1t36:A, 1t36:C, 1t36:E, 1t36:G
30 1wz2:A 948 59 0.0629 0.0232 0.3729 1.4 1wz2:B
31 2zzd:F 218 153 0.1143 0.1835 0.2614 3.0 2dd5:C, 2dd5:F, 2dd5:I, 2dd5:L, 2dxb:C, 2dxb:F, 2dxb:I, 2dxb:L, 2dxb:O, 2dxb:R, 2dxb:U, 2dxb:X, 2dxc:C, 2dxc:F, 2dxc:I, 2dxc:L, 3vyg:C, 3vyg:F, 3vyg:I, 3vyg:L, 2zzd:C, 2zzd:I, 2zzd:L
32 5dn1:A 240 73 0.0686 0.1000 0.3288 5.7
33 5oxf:C 601 45 0.0400 0.0233 0.3111 5.8 5oxf:D
34 9iye:B 173 33 0.0429 0.0867 0.4545 8.3 8i8j:A, 8i8j:B, 8i8j:C, 8i8j:D, 8i8j:E, 8i8j:F, 8i8k:A, 8i8k:B, 8i8k:C, 8i8k:D, 8i8k:E, 8i8k:F, 8i8l:A, 8i8l:B, 8i8l:C, 8i8l:D, 8i8l:E, 8i8l:F, 8i8m:A, 8i8m:B, 8i8m:C, 8i8m:D, 8i8m:E, 8i8m:F, 8i8n:A, 8i8n:B, 8i8n:C, 8i8n:D, 8i8n:E, 8i8n:F, 8i8o:A, 8i8o:B, 8i8o:C, 8i8o:D, 8i8o:E, 8i8o:F, 9iye:A, 9iye:C, 9iye:D, 9iye:E, 9iye:F, 9iyf:A, 9iyf:B, 9iyf:C, 9iyf:D, 9iyf:E, 9iyf:F, 9iyh:A, 9iyh:B, 9iyh:C, 9iyh:D, 9iyh:E, 9iyh:F, 8zn2:A, 8zn2:B, 8zn2:C, 8zn2:D, 8zn2:E, 8zn2:F, 8zn3:A, 8zn3:B, 8zn3:C, 8zn3:D, 8zn3:E, 8zn3:F
35 8k5o:C 346 59 0.0629 0.0636 0.3729 8.4
36 7tui:B 2033 118 0.0771 0.0133 0.2288 8.4 6u5v:B, 6u5w:B
37 3h70:A 342 37 0.0314 0.0322 0.2973 9.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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