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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TPVARYPPIVASMTADSKAARLRRIERWQATVHAAESVDEKLRILTKMQFMKYMVYPQTFALNADRWYQYFTKTVFLSGL
PPPPAEPPALDLAALRAVACDCLLQEHFYLRRRRRVHRYEESEVISLPFLDQLVSTLVGLLSPHNPALAAAALDYRCPVH
FYWVRGEEIIPRGHRRGRIDDLRYQIDDKPNNQIRISKQLAEFVPLDYSVPIEIPTIKCKPDKLPLFKRQYENHIFVGSK
TADPCCYGHTQFHLLPDKLRRERLLRQNCADQIEVVFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQAVITDGKYF
SFFCYQLNTLALTTQADQNNPRKNICWGTQSKPLYETIEDNDVKGFNDDVLLQIVHFLLNRPKEEK

The query sequence (length=386) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7l08:s 393 393 0.9948 0.9771 0.9771 0.0 8any:s, 7l20:s, 7o9m:s, 7odr:s, 7ods:s, 7odt:s, 8oir:Bi, 8oit:Bi, 8pk0:s, 7po4:s, 7qi4:s, 7qi5:s, 7qi6:s, 8qsj:s, 6vlz:s, 6vmi:s, 6zm5:s, 6zm6:s
2 7a5f:s3 370 381 0.9585 1.0000 0.9711 0.0 7a5g:s3, 7a5h:s, 7a5i:s3, 7a5j:s, 7a5k:s3, 6i9r:s, 3j7y:s, 3j9m:s, 8k2a:Sf, 8k2b:Sf, 6nu2:s, 6nu3:s, 7o9k:s, 7of0:s, 7of2:s, 7of3:s, 7of4:s, 7of5:s, 7of6:s, 7of7:s, 7og4:s, 7oi6:s, 7oi7:s, 7oi8:s, 7oi9:s, 7oia:s, 7oib:s, 7oic:s, 7oid:s, 7oie:s, 5ool:s, 5oom:s, 7pd3:s, 7qh6:s, 7qh7:s, 8qu5:s, 8xt0:Sf, 8xt1:Sf, 8xt2:Sf, 8xt3:Sf, 6zs9:s, 6zsa:s, 6zsb:s, 6zsc:s, 6zsd:s, 6zse:s, 6zsg:s
3 5aj4:Bw 387 387 0.8316 0.8295 0.8295 0.0 6gaw:Bw, 6gb2:Bw, 7nqh:Bw, 7nql:Bw, 7nsh:Bw, 7nsi:Bw, 7nsj:Bw, 8oin:Bi, 8oiq:Bi, 6ydp:Bw, 6ydw:Bw
4 8any:5 394 120 0.1036 0.1015 0.3333 2.33e-05 7a5f:53, 7a5g:53, 7a5h:5, 7a5i:53, 7a5j:5, 7a5k:53, 6i9r:5, 3j7y:5, 3j9m:5, 8k2a:Lk, 8k2b:Lk, 7l08:5, 7l20:5, 6nu2:5, 6nu3:5, 7o9k:5, 7o9m:5, 7odr:5, 7ods:5, 7odt:5, 7of0:5, 7of2:5, 7of3:5, 7of4:5, 7of5:5, 7of6:5, 7of7:5, 7og4:5, 7oi6:5, 7oi7:5, 7oi8:5, 7oi9:5, 7oia:5, 7oib:5, 7oic:5, 7oid:5, 7oie:5, 8oir:Bm, 8oit:Bm, 5ool:5, 5oom:5, 7pd3:5, 8pk0:5, 7po4:5, 7qh6:5, 7qh7:5, 7qi4:5, 7qi5:5, 7qi6:5, 8qsj:5, 8qu1:5, 8qu5:5, 6vlz:5, 6vmi:5, 8xt0:Lk, 8xt1:Lk, 8xt2:Lk, 8xt3:Lk, 6zm5:5, 6zm6:5, 6zs9:5, 6zsa:5, 6zsb:5, 6zsc:5, 6zsd:5, 6zse:5, 6zsg:5
5 5aj4:Ba 393 113 0.0933 0.0916 0.3186 0.007 6gaw:Ba, 6gb2:Ba, 7nqh:Ba, 7nql:Ba, 7nsh:Ba, 7nsi:Ba, 7nsj:Ba, 8oin:Bm, 8oiq:Bm, 6ydp:Ba, 6ydw:Ba
6 1f6d:A 376 135 0.0855 0.0878 0.2444 0.017 1f6d:B, 1f6d:C, 1f6d:D, 1vgv:B, 1vgv:C
7 2jac:A 108 32 0.0389 0.1389 0.4688 3.5 3c1s:A
8 4zoh:A 701 52 0.0492 0.0271 0.3654 4.3
9 3cni:A 145 43 0.0311 0.0828 0.2791 5.7
10 7d21:A 328 139 0.0829 0.0976 0.2302 7.4 7d1h:A, 7d1n:A, 7d1y:A, 7d2d:A, 7d2i:A, 7d2j:A, 4mhn:A, 4mhy:A, 4mhz:A
11 6knb:A 450 54 0.0466 0.0400 0.3333 9.0 6knc:A
12 1mex:H 211 45 0.0440 0.0806 0.3778 9.0 1a0q:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218