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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TPSYSLTPAEASAVAELTLELAAAYGSFGDPVLLRDLPRLAARLPEGVQDFLREFKLADRHGHTVIRGHDFDQRRIGPTP
DHWRGRVRPGPEFPEELLLMLYSALLGEPFGWATQQDGHLVHDIFPIRSHENDQLGMGSKQLLTWHTEDAFHPYRSDYLI
LGALRNPDHVPTTVGELDLSSLSAEDIDVLFEPRYHIAPDESHLPKNNTIATEEEAARFATIQRMIDERPLGPLLYGSRL
DPYMRLDPYFTSVPQDDTDARRAYDALFKVVDSGMREVVADQGDVLFIDNHRAVHGRLPFQARYDGTDRWLKRVCVTSDL
RRSREMRATSATRLLG

The query sequence (length=336) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4ne0:A 337 336 0.9970 0.9941 0.9970 0.0 4m25:A, 4m26:A, 4m26:C, 4m26:D, 4m27:A, 4m27:C, 4m27:D, 4m2c:B, 4m2c:C, 4m2c:D, 4m2e:B, 4m2e:C, 4m2e:D, 4m2f:A, 4m2f:C, 4m2f:D, 4m2g:A, 4m2g:C, 4m2g:D, 4m2i:A, 4ne0:C
2 4m25:B 317 336 0.9405 0.9968 0.9405 0.0 4m25:C, 4m25:D, 4m26:B, 4m27:B, 4m2f:B, 4m2g:B, 4m2i:B, 4m2i:C, 4m2i:D, 4ne0:B, 4ne0:D
3 6daw:A 342 330 0.4435 0.4357 0.4515 1.05e-80 6daw:B
4 6alm:A 338 333 0.4464 0.4438 0.4505 1.08e-77 6aln:A, 6alo:A, 6alp:A, 6alq:A, 6alr:A, 6dax:A, 6daz:A, 6db2:A, 9eqf:A, 6mp9:A, 2wbo:A, 2wbp:A, 2wbq:A, 6y0n:A, 6y12:A
5 7y5f:B 341 331 0.4226 0.4164 0.4290 5.95e-74 7vgn:A, 7y5f:A, 7y5i:A, 7y5i:B, 7y5p:A, 7y5p:B, 7yhe:A, 7yhe:B, 7yw9:A
6 6mp8:A 308 333 0.4196 0.4578 0.4234 2.39e-66
7 2og6:A 323 271 0.2798 0.2910 0.3469 1.01e-30 2og7:A
8 6euo:C 354 307 0.2470 0.2345 0.2704 2.64e-23 6euo:A, 6euo:B, 6euo:D, 6eur:A, 6eur:C, 6eur:D, 6exf:A, 6exf:C, 6exf:D, 6exh:A, 6exh:B, 6exh:C, 6exh:D, 6f9p:A, 6f9p:C, 6f9p:D
9 6f2a:C 326 332 0.2917 0.3006 0.2952 1.57e-22 6f2a:A, 6f2a:B, 6f2a:D, 6f2b:A, 6f2b:B, 6f2b:C, 6f2b:D, 6f6j:A, 6f6j:B, 6f6j:C, 6f6j:D
10 6eur:B 328 303 0.2381 0.2439 0.2640 4.10e-21 6exf:B
11 1ds1:A 323 286 0.2440 0.2539 0.2867 1.85e-16 1drt:A, 1dry:A, 1gvg:A
12 6vwq:A 325 287 0.2440 0.2523 0.2857 2.32e-14 6vwr:A
13 6f9p:B 289 302 0.2024 0.2353 0.2252 3.73e-09
14 6pbm:A 426 53 0.0565 0.0446 0.3585 0.88 6c4n:A, 6c4n:B, 6pbm:B, 6pbn:A, 6pbn:B, 6pbp:A, 6pbp:B, 6pbt:A, 6pbt:B
15 5hzd:A 476 25 0.0327 0.0231 0.4400 2.3 5i49:A, 5ido:A
16 6bbp:A 520 39 0.0417 0.0269 0.3590 2.6 2a5d:A, 2a5f:A, 2a5g:A, 6bbq:A, 1e0s:A, 1fgy:A, 1fhw:A, 1fhw:B, 1fhx:A, 1fhx:B, 4fme:C, 4fme:F, 2j5x:A, 2j5x:B, 4kax:A, 4kax:B, 3n5c:A, 3n5c:B, 3pcr:B, 2r09:A, 2r09:B, 2r0d:A, 2r0d:B, 3vhx:A, 3vhx:C, 3vhx:E, 3vhx:G, 2w83:A, 2w83:B, 2w83:E, 7xrd:A, 7xrd:B, 7xrd:C, 7xrd:D
17 8chf:A 280 64 0.0595 0.0714 0.3125 2.8 9ay7:A, 8chf:B, 3omv:A, 3omv:B
18 8swj:C 125 40 0.0327 0.0880 0.2750 5.2 4cri:A, 4cri:B, 8eom:A, 8eom:B, 8f0w:A, 8f0w:B, 2ig0:A, 3lgf:A, 3lgl:A, 3lh0:A, 2lvm:A, 2mwo:A, 2mwp:A, 6mxx:A, 6mxx:B, 6mxx:C, 6mxx:D, 6mxx:E, 6mxx:F, 6mxx:G, 6mxx:H, 6mxx:I, 6mxx:J, 6mxy:A, 6mxy:B, 6mxz:A, 6mxz:B, 6mxz:C, 6mxz:D, 6mxz:E, 6mxz:F, 6mxz:G, 6mxz:H, 6mxz:I, 6mxz:J, 4rg2:A, 4rg2:B, 8swj:A, 8swj:B, 8swj:D, 6upt:A, 6va5:A, 6vip:A, 6vip:B, 4x34:A, 4x34:B
19 2q4a:B 322 49 0.0476 0.0497 0.3265 6.7 2q4a:A, 1y0z:A, 1y0z:B
20 7yia:A 492 35 0.0446 0.0305 0.4286 7.7
21 3hft:A 242 123 0.0982 0.1364 0.2683 7.8
22 6u3e:A 397 39 0.0387 0.0327 0.3333 9.1 6u3e:B, 6u3g:A, 6u3g:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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