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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIW
LDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSA
SYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGL
IQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMG
AYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFM
LGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDP
ITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQT
KGSPESRLSFQHDPETSVLILRKPGVSVASDWSIHLR

The query sequence (length=597) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5ief:A 858 597 1.0000 0.6958 1.0000 0.0 5h9o:A, 5h9o:C, 5hjo:A, 5hjo:C, 5hjr:A, 5hjr:C, 5ied:A, 5iee:A, 5ieg:A, 7jty:A, 7jty:C, 7k9n:A, 7k9n:C, 7k9o:A, 7k9o:C, 7k9q:A, 7k9q:C, 7k9t:A, 7k9t:C, 7kad:A, 7kad:C, 7kb6:A, 7kb6:C, 7kb8:A, 7kb8:C, 7kbj:A, 7kbj:C, 7kbr:A, 7kbr:C, 7kry:A, 7kry:C
2 5dky:A 928 568 0.4690 0.3017 0.4930 0.0 5dkz:A, 5dl0:A
3 5kzw:A 850 616 0.3534 0.2482 0.3425 3.96e-104 8cb1:A, 8cb6:A, 5kzx:A, 5nn4:A, 5nn5:A, 5nn6:A, 5nn8:A, 7p2z:AaA, 7p32:AAA
4 3wem:A 830 585 0.3216 0.2313 0.3282 4.75e-90 3w37:A, 3wel:A, 3wen:A, 3weo:A
5 3l4u:A 864 614 0.3317 0.2292 0.3225 1.12e-86 3ctt:A, 3l4t:A, 3l4v:A, 3l4w:A, 3l4x:A, 3l4y:A, 3l4z:A, 2qmj:A
6 3lpp:B 869 632 0.3317 0.2278 0.3133 4.56e-80 3lpp:D
7 6c9x:A 666 558 0.2580 0.2312 0.2760 1.42e-78 6c9x:B, 6c9z:A, 6c9z:B, 6ca1:A, 6ca1:B, 6ca3:A, 6ca3:B, 3mkk:B, 3mkk:A, 3pha:A, 3pha:B, 3pha:C, 3pha:D, 3poc:B, 3poc:A
8 3top:A 890 642 0.3082 0.2067 0.2866 6.17e-68 3top:B
9 6jr7:A 812 551 0.2730 0.2007 0.2958 3.97e-67 6jr7:B, 6jr7:C, 6jr7:D, 6jr8:A, 6jr8:B, 6jr8:C, 6jr8:D
10 4ba0:A 781 518 0.2613 0.1997 0.3012 1.70e-56 4b9y:A, 4b9z:A, 5i23:A, 5i24:A, 5npb:A, 5npc:A, 5npd:A, 5npe:A, 7p4c:AAA, 7p4d:AAA, 8rw3:C, 8rw3:A, 8rw3:B
11 5jov:A 949 560 0.2563 0.1612 0.2732 8.67e-48
12 7knc:A 919 541 0.2412 0.1567 0.2662 1.33e-42
13 5x7o:A 1247 541 0.2362 0.1131 0.2606 3.71e-41 5x7o:B, 5x7p:B, 5x7p:A, 5x7q:A, 5x7q:B, 5x7r:A, 5x7r:B, 5x7s:A, 5x7s:B
14 2xvk:A 944 552 0.2362 0.1494 0.2554 4.66e-41 2xvl:A
15 7xoi:B 436 379 0.1759 0.2408 0.2770 1.35e-40 7xoi:D, 7xoi:F, 7xoi:H, 7xoi:J, 7xoi:L, 7xoi:N, 7xoi:P
16 2f2h:A 773 555 0.2429 0.1876 0.2613 2.80e-39 2f2h:B, 2f2h:C, 2f2h:D, 2f2h:E, 2f2h:F, 1xsk:A, 1xsk:B, 1xsk:C, 1xsk:E
17 5zn7:A 680 482 0.2127 0.1868 0.2635 7.71e-39 5zn7:C, 5zn7:D, 5zn7:F, 5zn7:H
18 6dru:A 718 495 0.2278 0.1894 0.2747 1.43e-35 6dru:B
19 5hxm:A 1060 497 0.2027 0.1142 0.2435 4.77e-33 5f7u:A, 5hpo:A, 5i0d:A, 5i0d:B, 4kmq:A, 4kwu:A
20 7xoi:A 465 195 0.1106 0.1419 0.3385 8.42e-31 7xoi:C, 7xoi:E, 7xoi:G, 7xoi:I, 7xoi:K, 7xoi:M, 7xoi:O
21 4xpq:A 670 532 0.2278 0.2030 0.2556 1.53e-29 4xpp:A, 4xps:A
22 5x3j:A 718 415 0.1977 0.1643 0.2843 3.05e-26 5x3j:B, 5x3k:A, 5x3k:B
23 5i0g:B 730 382 0.1776 0.1452 0.2775 4.61e-26 5f7s:A, 5f7s:B, 5i0e:B, 5i0f:B
24 7wj9:A 733 481 0.1826 0.1487 0.2266 8.34e-26 7wj9:B, 7wj9:C, 7wj9:D, 7wj9:F, 7wj9:E, 7wjb:A, 7wjc:A, 7wjd:A, 7wje:A, 7wjf:A
25 6m77:A 907 312 0.1240 0.0816 0.2372 2.38e-25 7f7q:A, 7f7r:A
26 4amw:A 1025 647 0.2462 0.1434 0.2272 3.92e-24 4amw:B, 4amw:C, 4amw:D, 4amx:A, 4amx:B, 4amx:C, 4amx:D, 2x2i:A, 2x2i:B, 2x2i:C, 2x2i:D, 2x2j:A, 2x2j:B, 2x2j:C, 2x2j:D
27 5aed:A 674 389 0.1692 0.1499 0.2596 9.65e-24 5aed:B, 5aee:A, 5aee:B, 5aeg:A, 5aeg:B, 5oht:A, 5oht:B
28 8r56:D 673 401 0.1575 0.1397 0.2344 2.93e-21 8r56:A, 8r56:B, 8r56:C
29 6pnr:A 667 391 0.1625 0.1454 0.2481 4.66e-21 6pnr:C
30 7ofx:B 665 395 0.1809 0.1624 0.2734 6.33e-20 7ofx:A, 7ofx:C, 7ofx:D, 5ohs:A, 5ohs:B, 5ohs:C, 5ohs:D, 5ohs:E, 5ohs:F, 5ohs:G, 5ohs:H, 5ohy:A, 5ohy:B, 5ohy:C, 5ohy:D
31 8j51:A 510 410 0.1742 0.2039 0.2537 1.73e-16 8j51:B, 8j52:A, 8j52:B
32 7qqg:B 623 424 0.1792 0.1717 0.2524 4.53e-13 7qqg:A, 7qqg:C, 7qqh:A, 7qqh:B, 7qqh:C, 7qqh:D
33 7qqg:D 496 423 0.1776 0.2137 0.2506 2.21e-11
34 5b8i:A 359 81 0.0352 0.0585 0.2593 0.74 6tz7:A
35 5vxc:A 301 115 0.0469 0.0930 0.2435 1.0 5vxo:A, 5vxo:B, 5vxo:C
36 7rka:A 211 98 0.0385 0.1090 0.2347 3.6
37 5oc2:A 441 106 0.0503 0.0680 0.2830 8.4 5oc2:B, 5oc3:A, 5oc3:B, 4wct:A, 4wct:B, 4xwz:A, 4xwz:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218