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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TPLDLLKLNLDERVYIKLRGARTLVGTLQAFDSHSNIVLSDAVETIYQLNNEELSESERRSEMVFIRGDTVTLISTP

The query sequence (length=77) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5vsu:C 81 77 0.9740 0.9259 0.9740 1.87e-50 6aso:C, 4c8q:C, 5gan:3, 4m7a:J, 4m7a:C, 4m7d:J, 4m7d:C, 5nrl:3
2 6ppn:C 75 78 0.5195 0.5333 0.5128 1.07e-19 6ppn:K, 6ppp:C, 6ppp:K, 6ppq:C, 6ppv:C
3 6qw6:63 85 82 0.4675 0.4235 0.4390 6.37e-19 6ah0:r, 6qx9:63, 8qxd:63, 8r08:63, 8r09:63, 8r0a:63, 8r0b:63, 8rm5:63
4 1loj:C 77 76 0.4416 0.4416 0.4474 2.29e-11 1loj:A, 1loj:B, 1loj:D, 1loj:E, 1loj:F, 1loj:G, 1loj:H, 1loj:I, 1loj:J, 1loj:K, 1loj:L, 1loj:M, 1loj:N
5 1i5l:C 74 77 0.4026 0.4189 0.4026 7.01e-11 1i5l:E, 1i5l:F, 1i5l:G, 1i5l:J, 1i5l:K, 1i5l:L, 1i5l:A, 1i5l:B, 1i5l:H
6 3jb9:J 73 71 0.3247 0.3425 0.3521 7.43e-08 3jb9:o
7 8ro0:d 94 64 0.2857 0.2340 0.3438 1.31e-06 8ro1:d
8 6n7p:M 107 65 0.2727 0.1963 0.3231 3.47e-06 7b9v:m, 7b9v:j, 6bk8:a, 7dco:n, 6exn:m, 6exn:j, 6g90:i, 6g90:u, 5gam:j, 5gan:m, 5gan:j, 5gao:m, 5gm6:g, 5gmk:g, 5gmk:e, 6j6g:g, 6j6g:e, 6j6h:g, 6j6h:e, 6j6n:g, 6j6n:e, 6j6q:g, 6j6q:e, 3jcm:Q, 3jcm:U, 5lj3:j, 5lj3:m, 5lj5:j, 5lj5:m, 5mps:j, 5mq0:j, 6n7r:M, 6n7x:M, 5nrl:u, 5nrl:m, 5nrl:i, 7oqb:u, 7oqc:i, 7oqe:i, 7oqe:u, 8w2o:M, 5wsg:g, 5wsg:W, 5y88:g, 5y88:n, 5ylz:g, 5ylz:n, 5zwm:R, 5zwm:c, 5zwm:n, 5zwn:c, 5zwo:c, 5zwo:R, 5zwo:n
9 6exn:r 75 66 0.2468 0.2533 0.2879 5.10e-06 7b9v:r, 7b9v:g, 6bk8:d, 7dco:k, 6exn:g, 6g90:g, 6g90:y, 5gam:g, 5gan:r, 5gan:g, 5gao:r, 5gm6:j, 5gmk:j, 5gmk:x, 6j6g:j, 6j6g:x, 6j6h:j, 6j6h:x, 6j6n:j, 6j6n:x, 6j6q:j, 6j6q:x, 5lj3:g, 5lj5:g, 5mps:g, 5mq0:g, 6n7p:Q, 6n7r:Q, 6n7x:Q, 5nrl:y, 5nrl:r, 5nrl:g, 7oqb:y, 7oqc:g, 7oqe:y, 8w2o:Q, 5wsg:j, 5wsg:K, 5y88:d, 5y88:k, 5ylz:d, 5ylz:k, 5zwm:V, 5zwm:k, 5zwn:g, 5zwo:k
10 7w59:b 102 66 0.2727 0.2059 0.3182 5.61e-06 7abg:m, 7abi:m, 6ahd:a, 7b0y:j, 8c6j:b, 8ch6:8, 7dvq:i, 9fmd:i, 8h6e:5a, 8h6e:4a, 8h6j:5a, 8h6j:4a, 8h6k:5a, 8h6l:5a, 8i0p:a, 8i0p:m, 8i0r:a, 8i0r:m, 8i0s:m, 8i0t:a, 8i0t:m, 8i0u:m, 8i0v:a, 8i0v:m, 8i0w:a, 8i0w:i, 6icz:i, 4pjo:B, 4pjo:b, 4pjo:P, 4pjo:p, 8q7q:b, 8q7v:b, 8q7w:b, 8q7x:b, 8q91:h, 6qdv:k, 8qo9:5b, 8qo9:4b, 6qw6:4b, 6qw6:5b, 6qx9:1b, 6qx9:5b, 6qx9:2b, 6qx9:4b, 8qxd:4b, 8qxd:5b, 8qzs:5b, 8qzs:2b, 8r08:1b, 8r08:4b, 8r08:5b, 8r09:5b, 8r0a:5b, 8r0b:5b, 8rc0:h, 8rm5:2b, 8rm5:5b, 8ro2:b, 7vpx:k, 7w59:i, 7w5a:b, 7w5a:i, 7w5b:b, 7w5b:i, 4wzj:B, 5xjc:b, 5xjc:i, 8y6o:a, 8y6o:h, 8y6o:o, 8y7e:i, 5yzg:b, 5yzg:i, 5z56:b, 5z56:i, 5z57:b, 5z57:i, 5z58:b, 5z58:i
11 1m8v:A 72 74 0.3506 0.3750 0.3649 6.22e-06 1m8v:M, 1m8v:C, 1m8v:K, 1m8v:F, 1m8v:H, 1m8v:E, 1m8v:I, 1m8v:D, 1m8v:J, 1m8v:B, 1m8v:L, 1m8v:G, 1m8v:N
12 5mkn:d 72 75 0.2987 0.3194 0.3067 9.08e-06 5mki:C, 5mki:D, 5mki:E, 5mki:F, 5mki:G, 5mki:I, 5mki:J, 5mki:K, 5mki:L, 5mkn:A, 5mkn:G, 5mkn:B, 5mkn:C, 5mkn:D, 5mkn:E, 5mkn:F, 5mkn:H, 5mkn:I, 5mkn:J, 5mkn:K, 5mkn:L, 5mkn:M, 5mkn:N, 5mkn:O, 5mkn:P, 5mkn:Q, 5mkn:R, 5mkn:T, 5mkn:U, 5mkn:V, 5mkn:W, 5mkn:X, 5mkn:Y, 5mkn:Z, 5mkn:a, 5mkn:b
13 6v4x:G 77 71 0.2727 0.2727 0.2958 9.42e-06 7a5p:k, 7a5p:g, 7abg:k, 7abi:k, 6ah0:n, 6ahd:S, 6ahd:f, 6ahd:n, 7b0y:h, 8c6j:r, 8c6j:g, 8ch6:m, 8ch6:9, 7dvq:g, 7dvq:n, 7evo:d, 9fmd:n, 9fmd:g, 8h6e:5f, 8h6e:4f, 8h6e:2f, 8h6j:5f, 8h6j:4f, 8h6j:2f, 8h6k:5f, 8h6k:4f, 8h6k:2f, 8h6l:5f, 8h6l:4f, 8h6l:2f, 8hk1:d, 8i0p:k, 8i0r:k, 8i0s:f, 8i0s:k, 8i0t:k, 8i0u:f, 8i0u:k, 8i0v:k, 8i0w:n, 6icz:g, 6id0:g, 6id1:g, 5mqf:k, 5mqf:d, 5o9z:k, 4pjo:G, 4pjo:g, 4pjo:U, 4pjo:u, 8q7q:g, 8q7v:g, 8q7w:g, 8q7x:g, 8q91:n, 6qdv:r, 6qdv:g, 8qo9:2g, 8qo9:4g, 7qtt:m, 6qw6:4g, 6qw6:5g, 6qx9:1g, 6qx9:5g, 6qx9:2g, 6qx9:4g, 8qxd:2g, 8qxd:4g, 8qxd:5g, 8qzs:5g, 8qzs:2g, 8qzs:4g, 8r08:1g, 8r08:2g, 8r08:4g, 8r08:5g, 8r09:2g, 8r09:5g, 8r09:4g, 8r0a:5g, 8r0a:2g, 8r0a:4g, 8r0b:2g, 8r0b:4g, 8r0b:5g, 8rc0:n, 8rm5:2g, 8rm5:5g, 8rm5:4g, 8ro2:g, 7vpx:d, 7vpx:n, 7w59:g, 7w59:n, 7w5a:g, 7w5a:n, 7w5b:g, 7w5b:n, 4wzj:G, 4wzj:N, 4wzj:U, 4wzj:GG, 4wzj:NN, 4wzj:UU, 4wzj:GGG, 4wzj:NNN, 4wzj:UUU, 4wzj:GGGG, 4wzj:NNNN, 4wzj:UUUU, 5xjc:g, 5xjc:n, 6y53:k, 6y5q:k, 8y6o:g, 8y6o:n, 8y6o:u, 8y7e:n, 5yzg:g, 5yzg:n, 5z56:g, 5z56:n, 5z57:g, 5z57:n, 5z58:g, 5z58:n
14 8y6o:q 104 64 0.2468 0.1827 0.2969 1.15e-05 7a5p:h, 7abg:a, 7abi:a, 6ah0:k, 6ah0:P, 6ahd:P, 6ahd:k, 8ch6:l, 8ch6:4, 7dvq:k, 8h6e:2c, 8h6j:2c, 8h6k:4c, 8h6k:2c, 8h6l:4c, 8h6l:2c, 8i0w:k, 6id0:k, 6id1:k, 5o9z:h, 5o9z:a, 4pjo:R, 7qtt:l, 8qzs:42, 7w59:k, 7w5a:k, 7w5b:k, 5xjc:k, 8y7e:k, 5yzg:k, 5z56:k, 5z57:k, 5z58:k
15 6tfl:A 62 50 0.2208 0.2742 0.3400 2.89e-05 6tfl:B, 6tfl:C, 6tfl:D, 6tfl:E, 6tfl:F, 6tfl:G, 6tfl:H, 6tfl:I, 6tfl:J, 6tfl:K, 6tfl:L, 6tfl:M, 6tfl:N
16 8ro0:n 77 69 0.2987 0.2987 0.3333 3.30e-05 8ro0:g, 8ro1:g
17 1lnx:A 74 70 0.3117 0.3243 0.3429 5.75e-05 1lnx:B, 1lnx:C, 1lnx:D, 1lnx:E, 1lnx:F, 1lnx:G
18 6v4x:B 76 64 0.2468 0.2500 0.2969 1.04e-04
19 4m7a:F 66 75 0.2857 0.3333 0.2933 1.21e-04
20 3swn:A 76 64 0.2468 0.2500 0.2969 1.66e-04 6ppq:E, 6ppv:E, 3swn:D, 3swn:P, 3swn:S
21 9fmd:b 87 36 0.1818 0.1609 0.3889 1.83e-04 7a5p:m, 7a5p:b, 7abg:f, 7abi:f, 6ah0:U, 8ch6:n, 5o9z:f, 6qdv:b, 7qtt:n, 4wzj:I, 4wzj:P, 4wzj:BB, 4wzj:II, 4wzj:PP, 4wzj:BBB, 4wzj:III, 4wzj:PPP, 4wzj:BBBB, 4wzj:IIII, 4wzj:PPPP
22 6ppq:A 69 66 0.2597 0.2899 0.3030 2.24e-04 6ppv:A
23 8ro0:b 98 63 0.2597 0.2041 0.3175 2.66e-04 8ro1:b
24 6v4x:D 106 70 0.3247 0.2358 0.3571 2.79e-04
25 3jb9:G 95 79 0.2987 0.2421 0.2911 3.38e-04 3jb9:l
26 4wzj:KK 104 71 0.2468 0.1827 0.2676 6.19e-04 7abg:h, 7abi:h, 6ahd:c, 7b0y:e, 8c6j:m, 8c6j:a, 7evo:a, 9fmd:k, 9fmd:d, 8h6e:5c, 8h6e:4c, 8h6j:5c, 8h6j:4c, 8h6k:5c, 8h6l:5c, 8hk1:a, 8i0p:c, 8i0p:h, 8i0r:c, 8i0r:h, 8i0s:c, 8i0s:h, 8i0t:h, 8i0u:c, 8i0u:h, 8i0v:c, 8i0v:h, 8i0w:c, 6icz:d, 6id0:d, 6id1:d, 5mqf:h, 5mqf:a, 4pjo:D, 4pjo:d, 4pjo:r, 8q7q:c, 8q7v:c, 8q7w:c, 8q7x:c, 8q91:j, 6qdv:m, 6qdv:j, 8qo9:22, 8qo9:52, 8qo9:42, 6qw6:42, 6qw6:52, 6qx9:12, 6qx9:52, 6qx9:22, 6qx9:42, 8qxd:22, 8qxd:42, 8qxd:52, 8qzs:52, 8qzs:22, 8r08:12, 8r08:42, 8r08:22, 8r08:52, 8r09:22, 8r09:52, 8r09:42, 8r0a:52, 8r0a:42, 8r0a:22, 8r0b:22, 8r0b:42, 8r0b:52, 8rc0:j, 8rm5:22, 8rm5:52, 8rm5:42, 8ro2:d, 7vpx:a, 7vpx:i, 7w59:d, 7w5a:d, 7w5b:d, 4wzj:D, 4wzj:K, 4wzj:R, 4wzj:DD, 4wzj:RR, 4wzj:DDD, 4wzj:KKK, 4wzj:RRR, 4wzj:DDDD, 4wzj:KKKK, 4wzj:RRRR, 5xjc:d, 6y53:h, 6y5q:h, 8y6o:c, 8y6o:j, 5yzg:d, 5z56:d, 5z57:d, 5z58:d
27 3jb9:H 76 53 0.2468 0.2500 0.3585 7.42e-04 3jb9:m
28 6qw6:66 72 76 0.3247 0.3472 0.3289 0.001 6qx9:66
29 6ppn:H 94 43 0.1688 0.1383 0.3023 0.001 6ppn:P, 6ppp:H, 6ppp:P
30 3jb9:E 98 66 0.2727 0.2143 0.3182 0.001 3jb9:b
31 6bk8:f 80 35 0.1558 0.1500 0.3429 0.006 6bk8:k, 7dco:a, 7dco:h, 6exn:k, 6exn:b, 6g90:s, 5gam:b, 5gan:k, 5gan:b, 5gao:k, 5gm6:k, 5gmk:k, 5gmk:s, 3jcm:S, 5lj3:b, 5lj5:b, 5mps:b, 5mq0:k, 5mq0:b, 5nrl:s, 5nrl:k, 5nrl:b, 7oqb:s, 7oqe:s, 5wsg:k, 5wsg:F, 5y88:a, 5y88:h, 5ylz:a, 5ylz:h, 5zwm:P, 5zwm:a, 5zwm:h, 5zwo:a, 5zwo:P
32 6g90:h 107 75 0.2727 0.1963 0.2800 0.008 6exn:l, 7oqc:h, 7oqe:h
33 6n7r:K 124 35 0.1558 0.0968 0.3429 0.012 7b9v:k, 7b9v:b, 6g90:b, 6j6g:k, 6j6g:s, 6j6h:k, 6j6h:s, 6j6n:k, 6j6n:s, 6j6q:k, 6j6q:s, 6n7p:K, 6n7x:K, 7oqc:b, 7oqe:b, 8w2o:K, 5zwn:a
34 3jb9:I 73 70 0.2468 0.2603 0.2714 0.030 3jb9:n
35 6j6g:m 119 87 0.2727 0.1765 0.2414 0.043 7b9v:l, 7b9v:h, 6j6g:z, 6j6h:m, 6j6h:z, 6j6n:m, 6j6n:z, 6j6q:m, 6j6q:z, 6n7p:L, 6n7r:L, 6n7x:L, 8w2o:L, 5zwn:b
36 6qw6:64 73 76 0.2597 0.2740 0.2632 0.050 6qx9:64
37 6qw6:68 95 59 0.2338 0.1895 0.3051 0.053 6ahd:z, 8h6e:6g, 8h6j:6g, 8h6k:6g, 8h6l:6g, 6qx9:68, 8qxd:68, 8r08:68, 8r09:68, 8r0a:68, 8r0b:68, 8rm5:68
38 5nrl:l 99 67 0.2468 0.1919 0.2836 0.055 6bk8:h, 7dco:m, 6exn:h, 6g90:t, 5gam:h, 5gan:l, 5gan:h, 5gao:l, 5gm6:m, 5gmk:m, 5gmk:z, 5lj3:h, 5lj3:l, 5lj5:h, 5lj5:l, 5mps:h, 5mq0:h, 5nrl:t, 5nrl:h, 7oqb:t, 7oqe:t, 5wsg:m, 5wsg:V, 5y88:f, 5y88:m, 5ylz:f, 5ylz:m, 5zwm:Q, 5zwm:m, 5zwo:Q, 5zwo:m
39 7abg:j 81 51 0.1818 0.1728 0.2745 0.14 7a5p:j, 7a5p:e, 7abi:j, 6ah0:c, 6ahd:e, 7b0y:g, 8c6j:p, 8c6j:e, 8ch6:i, 8ch6:1, 7dvq:e, 7dvq:l, 9fmd:l, 9fmd:e, 8h6e:5e, 8h6e:4e, 8h6j:5e, 8h6j:4e, 8h6k:5e, 8h6l:5e, 8i0p:e, 8i0p:j, 8i0r:e, 8i0r:j, 8i0s:e, 8i0s:j, 8i0t:e, 8i0t:j, 8i0u:e, 8i0u:j, 8i0v:e, 8i0v:j, 8i0w:e, 8i0w:l, 6icz:e, 6id0:e, 6id1:e, 5mqf:j, 5mqf:c, 5o9z:j, 4pjo:E, 4pjo:e, 4pjo:S, 4pjo:s, 8q7q:e, 8q7v:e, 8q7w:e, 8q7x:e, 6qdv:p, 6qdv:e, 8qo9:2e, 8qo9:5e, 8qo9:4e, 7qtt:i, 6qw6:4e, 6qw6:5e, 6qx9:1e, 6qx9:5e, 6qx9:2e, 6qx9:4e, 8qxd:2e, 8qxd:4e, 8qzs:5e, 8qzs:2e, 8qzs:4e, 8r08:1e, 8r08:2e, 8r08:4e, 8r09:2e, 8r09:5e, 8r09:4e, 8r0a:5e, 8r0a:2e, 8r0a:4e, 8r0b:4e, 8r0b:5e, 8rm5:2e, 8rm5:5e, 8rm5:4e, 8ro2:e, 6v4x:E, 7vpx:l, 7w59:e, 7w59:l, 7w5a:e, 7w5a:l, 7w5b:e, 7w5b:l, 4wzj:E, 4wzj:L, 4wzj:S, 4wzj:EE, 4wzj:LL, 4wzj:SS, 4wzj:EEE, 4wzj:LLL, 4wzj:SSS, 4wzj:EEEE, 4wzj:LLLL, 4wzj:SSSS, 5xjc:e, 5xjc:l, 8y6o:e, 8y6o:l, 8y6o:s, 8y7e:l, 5yzg:e, 5yzg:l, 5z56:e, 5z56:l, 5z57:e, 5z57:l, 5z58:e, 5z58:l
40 7b9v:p 77 69 0.2468 0.2468 0.2754 0.17 7b9v:e, 6bk8:c, 7dco:i, 6exn:p, 6exn:e, 6g90:e, 6g90:w, 5gan:p, 5gao:p, 5gm6:i, 5gmk:i, 5gmk:u, 6j6g:i, 6j6g:u, 6j6h:i, 6j6h:u, 6j6n:i, 6j6n:u, 6j6q:i, 6j6q:u, 5mps:e, 5mq0:e, 6n7p:O, 6n7r:O, 6n7x:O, 5nrl:w, 5nrl:p, 5nrl:e, 7oqb:w, 7oqc:e, 7oqe:w, 8w2o:O, 5wsg:i, 5wsg:G, 5y88:b, 5y88:i, 5ylz:b, 5ylz:i, 5zwm:T, 5zwm:i, 5zwn:e, 5zwo:T, 5zwo:i
41 6qw6:62 95 69 0.2338 0.1895 0.2609 0.23 6ahd:q, 8h6e:6a, 8h6j:6a, 8h6k:6a, 8h6l:6a, 6qx9:62
42 5zlu:EE 490 48 0.1948 0.0306 0.3125 0.69
43 7spb:C1 217 38 0.1948 0.0691 0.3947 1.1 7oko:9, 7oko:z, 7oko:4, 7oko:8, 7oko:B, 7oko:F, 7oko:G, 7oko:P, 7oko:A, 7oko:L, 7oko:Q, 7oko:V, 7oko:Z, 7oko:a, 7oko:e, 7oko:f, 7oko:j, 7oko:k, 7oko:p, 7oko:u, 7oko:y, 7spb:D1, 7spb:C2, 7spb:D2, 7spb:C3, 7spb:D3, 7spb:C4, 7spb:D4, 7spb:C5, 7spb:D5, 7spb:C6, 7spb:D6, 7spb:C7, 7spb:D7, 7spb:C8, 7spb:D8, 7spb:C9, 7spb:D9, 7spb:C10, 7spb:D10, 7spb:C11, 7spb:D11, 7spb:C12, 7spb:D12, 7spb:C13, 7spb:D13, 7spi:C1, 7spi:D1, 7spi:C2, 7spi:D2, 7spi:C3, 7spi:D3, 7spi:C4, 7spi:D4, 7spi:C5, 7spi:D5, 7spi:C6, 7spi:D6, 7spi:C7, 7spi:D7, 7spi:C8, 7spi:D8, 7spi:C9, 7spi:D9, 7spi:C10, 7spi:D10, 7spi:C11, 7spi:D11, 7spi:C12, 7spi:D12, 7spi:C13, 7spi:D13
44 5yzg:D 1908 39 0.1818 0.0073 0.3590 1.5 6ahd:D, 8bc8:B, 8bc9:B, 8bca:B, 8bcb:B, 8bcc:B, 8bcd:B, 8bce:B, 8bcf:B, 8bcg:B, 8bch:B, 7bdi:B, 7bdj:B, 7bdk:B, 7bdl:B, 4f92:B, 4f93:B, 6ff7:r, 8h6k:5D, 8h6l:5D, 4kit:B, 5o9z:C, 7os1:B, 8qo9:B, 8qzs:B, 5urj:A, 5urk:A, 5urm:A, 5urm:B, 5xjc:D
45 5hs2:A 226 22 0.1169 0.0398 0.4091 1.8
46 7dp4:A 287 66 0.2987 0.0801 0.3485 3.7 7dp5:A, 7dp6:A
47 2sem:B 59 33 0.1429 0.1864 0.3333 5.6 1sem:A, 1sem:B, 2sem:A, 3sem:A, 3sem:B
48 2rmx:A 118 55 0.2208 0.1441 0.3091 5.7 2yu7:A
49 3k28:A 423 39 0.1818 0.0331 0.3590 6.1 3k28:B, 3k28:C, 3k28:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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