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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TPDEKKDEIEKIKAYPYMEGEPEDDVYLKRLYPRQIYEVEKAVHLLKKFQILDFTSPKQSVYLDLTLDMALGKKKNVEPF
TSVLSLPYPFASEINKVAVFTENASEVKIAEENGAAFAGGTSLIQKIWDDEIVADFYVAVPEIMPELNRLRKKLNKKYPK
LSRNSIGRDIPKMLELFKNGHEIKVDEERENFLQTKIATLDMSSDQIAANLQAVINEVCRHRPLNLGPFVVRAFLRSSTS
EGLLLKIDPLLP

The query sequence (length=252) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8any:z 252 252 1.0000 1.0000 1.0000 0.0 7a5k:n, 7qi5:z, 7qi6:z
2 8oir:Bj 164 110 0.3889 0.5976 0.8909 2.81e-62 8oit:Bj, 7qi4:z
3 8oir:Bj 164 73 0.2897 0.4451 1.0000 1.28e-46 8oit:Bj, 7qi4:z
4 8oin:Bj 164 114 0.3413 0.5244 0.7544 1.37e-54 8oiq:Bj
5 8oin:Bj 164 74 0.2698 0.4146 0.9189 5.13e-43 8oiq:Bj
6 4qvi:A 229 228 0.2222 0.2445 0.2456 1.29e-14 7a5f:n, 7a5g:n, 7a5j:n, 5a9z:AC, 5aa0:AC, 2hw8:A, 5imq:Z, 5imr:Z, 7lh5:BC, 7lh5:DC, 6n1d:AL01, 6n1d:BL01, 5npm:A, 2om7:K, 5ot7:f, 6q95:A, 4qg3:A, 4reo:A, 4u1u:B5, 4u1v:B5, 4u20:B5, 4u24:B5, 4u25:B5, 4u26:B5, 4u27:B5, 3u4m:A, 3u56:A, 3umy:A, 5uq7:C, 5uq8:C, 4v4p:AC, 4v4x:BC, 4v4y:BC, 4v4z:BC, 4v51:BC, 4v51:DC, 4v5a:BC, 4v5a:DC, 4v5c:BC, 4v5c:DC, 4v5d:BC, 4v5d:DC, 4v5e:BC, 4v5e:DC, 4v5f:BC, 4v5f:DC, 4v5g:BC, 4v5g:DC, 4v5k:BC, 4v5k:DC, 4v5l:BC, 4v5m:BC, 4v5n:BC, 4v5p:BC, 4v5p:DC, 4v5q:BC, 4v5q:DC, 4v5r:BC, 4v5r:DC, 4v5s:BC, 4v5s:DC, 4v68:BC, 4v6a:BC, 4v6a:DC, 4v7l:BC, 4v7l:DC, 4v7m:BC, 4v7m:DC, 4v8j:BC, 4v8j:DC, 4v8o:BC, 4v8q:AC, 4v8u:BC, 4v8u:DC, 4v8y:By, 4v8y:CL, 4v90:BC, 4v97:BC, 4v97:DC, 4v9h:BC, 4v9j:BC, 4v9j:DC, 4v9k:BC, 4v9k:DC, 4v9l:BC, 4v9l:DC, 4v9m:BC, 4v9m:DC, 4w29:BC, 4w29:DC, 4wf1:B5, 4woi:B5, 1zho:A, 1zho:C, 1zho:E, 1zho:G, 5zlu:Y
7 8fmw:AC 221 210 0.1944 0.2217 0.2333 1.56e-07
8 6ha8:8 212 215 0.1825 0.2170 0.2140 0.005
9 7p7q:F 226 198 0.1706 0.1903 0.2172 0.025 7p7r:F, 7p7s:F, 7p7t:F
10 6l3a:B 393 128 0.1190 0.0763 0.2344 1.00 6l39:A, 6l39:B, 6l3a:A
11 4v9i:BC 190 44 0.0556 0.0737 0.3182 1.2 4v9i:DC, 4wt8:CA, 4wt8:DA
12 6yxy:EF 302 53 0.0595 0.0497 0.2830 1.4 6yxx:EF
13 8qnc:A 486 45 0.0595 0.0309 0.3333 1.7 8qmy:A, 8qmy:B, 8qmy:C, 8qnb:A, 8qnr:A
14 1u63:A 214 93 0.0873 0.1028 0.2366 2.8 1i2a:A, 1u63:C
15 4fr4:A 350 33 0.0437 0.0314 0.3333 4.8 4fr4:B, 4fr4:C, 4fr4:D, 4fr4:E, 4fr4:F
16 4kps:A 324 51 0.0675 0.0525 0.3333 6.5 4kps:E
17 7bsp:A 1028 64 0.0714 0.0175 0.2812 8.9 7bsq:A, 7vsh:A
18 5ixm:A 543 95 0.0992 0.0460 0.2632 9.0 5ixm:C, 5ixm:E, 5ixm:G
19 3tji:A 399 57 0.0675 0.0426 0.2982 9.6 3tji:B, 3tji:C, 3tji:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218