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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TNKPIVLSTFNFGLHANVEAWKVLSKGGKALDAVEKGVRLVEDDPTERSVGYGGRPDRDGRVTLDACIMDENYNIGSVAC
MEHIKNPISVARAVMEKTPHVMLVGDGALEFALSQGFKKENLLTAESEKEWKEWLYKPIVNIENHDTIGMIALDAQGNLS
GACTTSGMAYKMHGRVGDSPIIGAGLFVDNEIGAATATGHGEEVIRTVGTHLVVELMNQGRTPQQACKEAVERIVKIVNR
RGKNLKDIQVGFIALNKKGEYGAYCIQDGFNFAVHDQKGNRLETPGFALK

The query sequence (length=290) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1p4v:A 295 294 0.9931 0.9763 0.9796 0.0 9gac:A, 9gac:C, 9gaf:A, 9gaf:C, 2gl9:B, 2gl9:D, 3ljq:C, 1p4v:C, 4r4y:A
2 4osx:A 300 252 0.3276 0.3167 0.3770 4.27e-44 4o0d:A, 4o0d:B, 4o0f:A, 4o0f:B, 4o0h:A, 4o0h:B, 4osx:B, 4osy:A, 4osy:B, 4pvr:A, 4pvr:B, 4pvs:A, 4pvs:B, 4zm9:A, 4zm9:B, 4zm9:C, 4zm9:D
3 4o48:A 298 243 0.3172 0.3087 0.3786 3.77e-35 4o48:B
4 1jn9:A 158 109 0.1655 0.3038 0.4404 1.94e-20 8c0i:AAA
5 1apz:B 141 139 0.1724 0.3546 0.3597 8.77e-18 1apz:D
6 2a8j:B 313 200 0.1966 0.1821 0.2850 1.80e-16 2a8j:A, 2a8m:A
7 2gez:B 133 114 0.1552 0.3383 0.3947 6.46e-16 2gez:D, 2gez:F, 2gez:H
8 8c23:DDD 135 121 0.1517 0.3259 0.3636 9.49e-16 8c23:HHH, 2zal:B, 2zal:D
9 4pv2:C 158 157 0.1724 0.3165 0.3185 8.39e-13 4pu6:A, 4pu6:C, 4pv2:A, 4pv3:A, 4pv3:C
10 2gez:C 166 123 0.1621 0.2831 0.3821 7.01e-12 2gez:A, 2gez:E, 2gez:G
11 4pu6:B 131 132 0.1483 0.3282 0.3258 5.23e-11
12 5msy:A 457 57 0.0586 0.0372 0.2982 0.37 5msy:B, 5msy:C
13 7ojr:A 445 40 0.0517 0.0337 0.3750 1.3 7oml:A
14 1m32:B 362 45 0.0517 0.0414 0.3333 1.8 1m32:A, 1m32:C, 1m32:D, 1m32:E, 1m32:F
15 2g88:A 331 36 0.0483 0.0423 0.3889 2.6 2odn:A, 2odw:A, 2oep:A, 1ube:A, 1ubf:A, 1ubg:A, 2zr9:A, 2zra:A, 2zrd:A, 2zre:A, 2zrf:A, 2zrg:A, 2zri:A, 2zrj:A, 2zrk:A, 2zrl:A, 2zrm:A, 2zro:A, 2zrp:A
16 4plt:B 319 80 0.0724 0.0658 0.2625 4.8 4plh:A, 4plh:B, 4plh:C, 4plh:D, 4plt:A, 4plt:C, 4plt:D, 4plv:A, 4plv:B, 4plv:C, 4plv:D, 4plw:A, 4plw:B, 4plw:C, 4plw:D, 4ply:B, 4ply:A, 4ply:C, 4ply:D, 4ply:F, 4ply:E, 4ply:G, 4ply:H
17 2ynp:A 601 85 0.0724 0.0349 0.2471 5.5 8ens:A, 8enw:A, 8enw:B, 8enx:A, 8hqt:A, 8hqv:A, 8hqx:A, 4j73:A, 4j77:A, 4j77:B, 4j78:A, 4j79:A, 4j81:B, 4j81:A, 4j82:A, 4j82:B, 4j84:A, 4j84:B, 4j86:A, 4j86:B, 2ynn:A
18 6hq7:A 377 110 0.0931 0.0716 0.2455 5.9 6hq3:B, 6hq3:C, 6hq3:A, 6hq3:D, 6hq4:A, 6hq4:B, 6hq5:A, 6hq5:B, 6hq7:B
19 6a8a:A 327 72 0.0828 0.0734 0.3333 9.6 6a8a:B, 6a8b:A, 6a8b:B, 6a8c:A, 6a8c:B, 5zwy:A, 5zwy:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218