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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TMLILLCNVNIYAPNPLGIKDVLIAGNKIAAIYDHGQGEITIPKQWPVKVINFDGAILTPGFIDSHAHITGGGGQAGFAT
QVPPVGLTEFTHAGVTTVVGLLGTDDTTRSTENLLSRVYGLREEGLSAYCWTGGYHFPLTTITGSAKSDIAFLEPVIGIG
EFAISDHRSSQPTFEEVIRLASETHVAGLITGKAGVIHFHLGDGERRLELIERAIRETELPARVFNPTHVNRNKPLFEDS
CKLLSKGCHIDLTAFPAGTAQPGWEACDAIEMAVERQLPLEQITLSSDGGGCLPCMDFGRASTLGETLVATLNKGLSLET
VLPMLTSNVANILRFKNKGQIAVGFDADLLVMNEKYEITDVMAQGVWHKQNNQTMIKGTFE

The query sequence (length=381) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5xgx:A 381 381 1.0000 1.0000 1.0000 0.0 5xgw:A, 5xgw:B, 5xgx:B
2 8dqn:C 388 390 0.6509 0.6392 0.6359 0.0 8dqn:A, 8dqn:B, 8dqn:D, 8dqn:E, 8dqn:F, 8dqn:G, 8dqn:H
3 1onx:A 389 387 0.4304 0.4216 0.4238 8.01e-90 2aqo:A, 2aqo:B, 2aqv:A, 2aqv:B, 1onw:A, 1onw:B, 1onx:B, 1po9:A, 1po9:B, 1poj:A, 1poj:B, 1pok:B, 1pok:A, 1ybq:A, 1ybq:B
4 7cf6:A 384 377 0.4068 0.4036 0.4111 1.94e-84 7cdh:X, 7cf6:B, 7cf6:C, 7cf6:D
5 2oof:A 403 141 0.0945 0.0893 0.2553 0.055 2q09:A
6 8hfd:A 452 53 0.0472 0.0398 0.3396 0.071 3e74:B, 8hfd:B, 8hfd:C, 8hfd:D
7 8hfd:A 452 101 0.0682 0.0575 0.2574 0.099 3e74:B, 8hfd:B, 8hfd:C, 8hfd:D
8 3e74:A 429 53 0.0472 0.0420 0.3396 0.078 3e74:C, 3e74:D
9 7lkk:A 411 76 0.0525 0.0487 0.2632 0.13 7lkj:A, 7lkj:B, 7lkj:C, 7lkk:B, 7lkk:C, 7lkk:D
10 1m7j:A 474 53 0.0472 0.0380 0.3396 0.14 1rjp:A, 1rjq:A, 1rjr:A, 1rk5:A, 1rk6:A, 1v4y:A, 1v51:A
11 6fv3:D 350 74 0.0709 0.0771 0.3649 0.18
12 6fv4:B 385 74 0.0709 0.0701 0.3649 0.21 6fv3:A, 6fv3:B, 6fv3:C, 6fv4:A
13 3mpg:A 426 150 0.0945 0.0845 0.2400 0.26 3mpg:B, 4yiw:A, 4yiw:B
14 2xr1:B 611 148 0.1024 0.0638 0.2635 0.31 2xr1:A
15 3gri:B 423 112 0.0761 0.0686 0.2589 0.38 3gri:A
16 2ogj:A 379 79 0.0709 0.0712 0.3418 0.40 2ogj:B, 2ogj:C, 2ogj:D, 2ogj:E, 2ogj:F
17 3iv8:A 379 153 0.0997 0.1003 0.2484 0.43
18 8je0:A 378 76 0.0656 0.0661 0.3289 0.53 8je0:B, 8je0:C, 8je0:D
19 5e5c:C 479 77 0.0604 0.0480 0.2987 0.54 6ajd:A, 6ajd:B, 7e3u:A, 7e3u:B, 5e5c:A, 6klk:A, 6klk:B, 8wq9:A, 8wq9:B, 5ykd:A, 5ykd:B, 5ykd:C, 5ykd:D
20 5t5i:A 569 74 0.0604 0.0404 0.3108 0.54 5t5i:I, 5t5m:A, 5t61:A, 5t61:G, 5t61:M, 5t61:S, 5t61:Y, 5t61:e, 5t61:k, 5t61:q
21 5t5i:A 569 60 0.0420 0.0281 0.2667 8.2 5t5i:I, 5t5m:A, 5t61:A, 5t61:G, 5t61:M, 5t61:S, 5t61:Y, 5t61:e, 5t61:k, 5t61:q
22 4tqt:D 481 49 0.0499 0.0395 0.3878 0.55 4tqt:A, 4tqt:B, 4tqt:C, 4tqt:E, 4tqt:F
23 2z00:A 426 72 0.0604 0.0540 0.3194 0.67
24 3fp2:A 483 81 0.0630 0.0497 0.2963 0.81 3fp4:A, 3lca:A
25 4bjh:A 422 53 0.0472 0.0427 0.3396 0.82 3d6n:A
26 2vun:A 385 51 0.0420 0.0416 0.3137 0.85 2vun:B, 2vun:C, 2vun:D
27 6ohb:A 435 47 0.0367 0.0322 0.2979 0.88 6ohb:B, 6ohb:C, 6ohb:D, 6ohc:A, 6ohc:B, 6ohc:C, 6ohc:D
28 6gdd:A 375 53 0.0472 0.0480 0.3396 0.94 6gde:A, 6gdf:A, 1xrf:A, 1xrt:A, 1xrt:B
29 3dc8:A 483 45 0.0420 0.0331 0.3556 1.3 3dc8:B
30 3n2c:A 408 65 0.0472 0.0441 0.2769 1.4 3feq:A, 3feq:B, 3feq:C, 3feq:D, 3feq:E, 3feq:F, 3feq:G, 3feq:H, 3feq:I, 3feq:J, 3feq:K, 3feq:L, 3feq:M, 3feq:N, 3feq:O, 3feq:P, 3n2c:B, 3n2c:C, 3n2c:D, 3n2c:E, 3n2c:F, 3n2c:G, 3n2c:H, 3n2c:I, 3n2c:J, 3n2c:K, 3n2c:L, 3n2c:M, 3n2c:N, 3n2c:O, 3n2c:P
31 3nqb:A 587 49 0.0420 0.0273 0.3265 1.5 3nqb:B, 3t81:A, 3t81:B
32 4cqb:A 402 60 0.0446 0.0423 0.2833 1.7 5akq:A, 5akq:B, 4cqb:B, 4cqc:A, 4cqc:B, 4cqd:A, 4cqd:B, 2qt3:A, 2qt3:B
33 3be7:A 398 51 0.0551 0.0528 0.4118 2.2 3be7:E, 3be7:B, 3be7:D, 3be7:C, 3be7:F, 3be7:G, 3be7:H, 3dug:A, 3dug:B, 3dug:C, 3dug:D, 3dug:E, 3dug:F, 3dug:G, 3dug:H
34 4cns:D 479 123 0.0814 0.0647 0.2520 2.7 4cns:A, 4cns:B, 4cns:C
35 2fty:A 532 88 0.0656 0.0470 0.2841 2.9 2fty:B, 2fty:C, 2fty:D, 2fvk:A, 2fvk:B, 2fvk:C, 2fvk:D, 2fvm:A, 2fvm:B, 2fvm:C, 2fvm:D
36 2g3f:A 414 27 0.0262 0.0242 0.3704 3.5 2bb0:A, 2bb0:B, 2g3f:B
37 1nfg:A 457 69 0.0525 0.0438 0.2899 3.8 1nfg:B, 1nfg:C, 1nfg:D
38 1gkp:A 458 25 0.0367 0.0306 0.5600 3.8 1gkp:B, 1gkp:C, 1gkp:D, 1gkp:E, 1gkp:F, 1gkq:A, 1gkq:B, 1gkq:C, 1gkq:D
39 7r78:A 1880 84 0.0761 0.0154 0.3452 4.3
40 4ckl:A 450 71 0.0525 0.0444 0.2817 4.7
41 7nut:A 401 57 0.0446 0.0424 0.2982 4.8 7nut:B, 7nuu:A, 7nuu:B
42 6i5s:A 445 173 0.1076 0.0921 0.2370 5.2
43 1gkr:A 451 67 0.0446 0.0377 0.2537 6.4 1gkr:B, 1gkr:C, 1gkr:D
44 1a5o:C 566 56 0.0551 0.0371 0.3750 7.2 1a5n:C, 1ef2:A, 1ejr:C, 1ejs:C, 1ejt:C, 1eju:C, 1ejv:C, 1fwa:C, 1fwb:C, 1fwc:C, 1fwd:C, 1fwe:C, 1fwf:C, 1fwg:C, 1fwh:C, 1fwi:C, 1fwj:C, 2kau:C, 1krb:C, 1krc:C
45 6bs3:A 330 124 0.0787 0.0909 0.2419 7.5 6bs4:A, 6bs5:A
46 7aih:Z 150 22 0.0236 0.0600 0.4091 7.8 7am2:Z, 7ane:Z
47 2nv9:B 372 94 0.0656 0.0672 0.2660 7.9 2nv9:A, 2nv9:C, 2nv9:D, 2nv9:E, 2nv9:F, 2nv9:G, 2nv9:H, 2nva:A, 2nva:B, 2nva:C, 2nva:D, 2nva:E, 2nva:F, 2nva:G, 2nva:H
48 3sfw:A 461 49 0.0499 0.0412 0.3878 8.1 3sfw:B
49 2vr2:A 478 31 0.0341 0.0272 0.4194 8.5
50 7cfc:C 179 49 0.0420 0.0894 0.3265 8.8 7cfc:A, 7cfc:B, 7cfc:D, 7cfc:E
51 8c41:A 720 62 0.0499 0.0264 0.3065 9.2 8c41:B
52 5hmd:A 456 56 0.0472 0.0395 0.3214 9.4 5hmd:B, 5hme:A, 5hme:B, 5hmf:A, 5hmf:B, 4lh8:A, 4lh8:B, 3ls9:A, 3ls9:B, 3lsb:A, 3lsb:B, 3lsc:A, 3lsc:B
53 2xco:A 636 42 0.0341 0.0204 0.3095 9.5
54 4v1x:E 474 22 0.0236 0.0190 0.4091 9.9 4v1x:A, 4v1x:B, 4v1x:C, 4v1x:D, 4v1x:F, 4v1y:A, 4v1y:B, 4v1y:C, 4v1y:D, 4v1y:E, 4v1y:F, 4v1y:G, 4v1y:H, 4v1y:I, 4v1y:J, 4v1y:K, 4v1y:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218