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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TLTQKFHGLLQHPLEPLFLPKNDGTLFYDLPERFLTSRYSPIGQNLANRFGPNSPASSQVSNPPTVVTIKDLDELPDLTF
ATWIKRRDSFSLFNPEHRKAAGKLTKLFLDQPNADRLVDVAAYARDRLNAPLFQYALSVALLHRPDTKSVSVPSLLHLFP
DQFIDPAAQVRMMEEGSIVLDENRMPIPIPMNYTATDAEPEQRMAFFREDIGVNLHHWHWHLVYPASGPPDVVRKDRRGE
LFYYMHQQLLARYQIDRYAQGLGRIEPLANLREPVREAYYPKLLRTSNNRTFCPRYPGMTISDVARSADRLEVRIADIES
WLPRVLEAIDAGFAVSDDGVRVPLDETRGIDVLGNILERSAISINRNLYGDVHNMGHVLLAFIHDPRGTYLESSGVMGGV
ATAMRDPIFYRWHKFIDNIFLRNKARLAPYTMAELSNSNVTLEALETQLDRAGGAVNSFVTFWQRSQVDLRAGIDFSAAG
SAFVSFTHLQCAPFVYRLRINSTARSNRQDTVRIFLLPRQNEQGRPLSFEDRRLLAIELDSFRVNLRPGMNNIVRQSSNS
SVTIPFERTFGNQSRFCGCGWPAHMLLPKGNANGVEFDLFAMVSRFEDDNANVNYDENAGCDDSYAFCGLRDRVYPSRRA
MGFPFDRRASNGVRSVADFVAPYKNMRLATVTLRFMNTIIDR

The query sequence (length=682) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4yzw:B 682 682 1.0000 1.0000 1.0000 0.0 4yzw:A
2 8jib:E 661 675 0.4736 0.4887 0.4785 0.0 8ji8:A, 8ji8:B, 8ji8:C, 8ji8:D, 8jib:A, 8jib:B, 8jib:C, 8jib:D, 8jib:F, 8jib:G, 8jib:H, 8jib:I, 8jib:J, 8jib:K, 8jib:L
3 3hhs:B 656 674 0.4223 0.4390 0.4273 0.0
4 3hhs:A 669 677 0.4120 0.4200 0.4151 4.47e-178
5 1nol:A 607 596 0.3284 0.3690 0.3758 1.45e-147 1ll1:A, 1lla:A
6 1oxy:A 573 591 0.3240 0.3857 0.3739 9.36e-145
7 3wky:A 655 655 0.2947 0.3069 0.3069 5.16e-95 3wky:B
8 6l8s:A 650 643 0.2786 0.2923 0.2955 1.86e-79 1hc1:A, 1hc1:B, 1hc1:C, 1hc1:D, 1hc1:E, 1hc1:F, 6l8s:B, 6l8s:C
9 1hcy:A 644 666 0.2845 0.3012 0.2913 4.92e-78
10 8cad:A 636 601 0.2375 0.2547 0.2696 3.20e-44 8cad:B, 8cad:C, 8cad:D, 8cad:E, 8cad:F
11 8can:A 683 613 0.2346 0.2343 0.2610 3.46e-44 8can:B, 8can:C, 8can:D, 8can:E, 8can:F
12 3gwj:D 674 622 0.2214 0.2240 0.2428 1.90e-40 3gwj:A, 3gwj:F, 3gwj:B, 3gwj:E, 3gwj:C
13 8ca9:A 680 583 0.2155 0.2162 0.2521 1.37e-34 8ca9:B, 8ca9:C, 8po9:D, 8po9:A, 8po9:B, 8po9:C, 8po9:E, 8po9:F
14 8ca9:D 678 503 0.1804 0.1814 0.2445 4.65e-31 8ca9:E, 8ca9:F
15 5yy2:A 569 598 0.2053 0.2460 0.2341 1.17e-18
16 3dje:B 437 123 0.0469 0.0732 0.2602 1.8 3djd:A, 3djd:B, 3dje:A
17 2j1p:A 276 52 0.0279 0.0688 0.3654 2.7
18 6ln0:A 425 77 0.0367 0.0588 0.3247 2.9
19 1br6:A 268 114 0.0455 0.1157 0.2719 7.4 1br5:A, 5ddz:A, 3ej5:X, 4esi:A, 5gu4:A, 5gu4:B, 3hio:A, 4huo:X, 4hup:X, 4hv3:A, 4hv7:X, 8i7p:A, 1ifs:A, 1ifu:A, 1il3:A, 1il4:A, 1il5:A, 1il9:A, 1j1m:A, 7kc9:D, 7kd0:A, 7kdm:D, 7kdu:A, 4lgr:A, 7mln:A, 7mlo:A, 7mlo:B, 7mlp:A, 7mlt:A, 4mx1:A, 4mx5:X, 1obt:A, 6obg:B, 6ocd:A, 6ocd:C, 2p8n:A, 2pjo:A, 3px8:X, 3px9:X, 4q2v:A, 2r2x:A, 3rti:A, 3rtj:A, 1rzo:A, 1rzo:C, 8t9v:A, 8tab:A, 8tad:A, 6urw:A, 6urx:A, 6ury:A, 7xzs:A, 7xzt:A, 7xzu:A, 7xzw:A, 7y02:A, 7y03:A, 7y05:A, 7y06:A, 7y07:A, 7y08:A, 7y4k:A, 7y4m:A, 4z9k:A
20 6l2u:A 103 78 0.0337 0.2233 0.2949 8.9 6l2u:B
21 8www:A 501 62 0.0235 0.0319 0.2581 9.4 8www:B
22 6vfv:A 222 26 0.0176 0.0541 0.4615 9.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218