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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TLDVAAQCFLNSLVRETKDWRLTEYQPTQLIIPLGEQQALHFRVAYFSPTQHHRFEFPARLVTASGSHPVDFATLSRLIV
DKLQHQLLLPATSCETFHQRVMESHAHTQQAIDARHDWAALREKALNFGEAEQALLVGHAFHPAPKSHEPFNQQEAERYL
PDFAPHFPLRWFAVNKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQEWCQELVAKGLIK
DLGEAGAPWLPTTSSRSLYCATSRDMIKFSLSVRLTNSVRTLSVKEVKRGMRLARLAQTDDWQTLQARFPTFRVMQEDGW
AGLRDLHGNIMQESLFALRENLLVDQPQSQTNVLVSLTQAAPDGGDSLLVAAVKRLSDRLGITAQQAAHAWVDAYCHQVL
KPLFTAEADYGLVLLAHQQNILVQMLGDLPVGLIYRDCQGSAFMPHAAGWLDTIGEAQAENVFTREQLLRYFPYYLLVNS
TFAVTAALGAAGLDSEANLMARVRTLLAEMRDQVTHKTCLNYVLENPYWNVKGNFFCYLNDHYFDFANPLLA

The query sequence (length=552) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5jm8:A 556 555 0.9982 0.9910 0.9928 0.0 5jm8:B, 5jm8:C, 5jm8:D, 5jm8:E, 5jm8:F, 5jm8:G, 5jm8:H
2 2x3j:A 586 404 0.1902 0.1792 0.2599 5.81e-14 2w02:A, 2w02:B, 2w03:A, 2w03:B, 2w04:B, 2x3j:B, 2x3k:A, 2x3k:B
3 3to3:B 595 322 0.1304 0.1210 0.2236 1.69e-10
4 7cbb:A 576 175 0.0888 0.0851 0.2800 3.19e-08 7cbb:B
5 2x0q:A 582 419 0.1685 0.1598 0.2220 9.62e-06 2x0p:A
6 7tgn:B 576 335 0.1449 0.1389 0.2388 7.36e-04 7tgn:A, 7tgn:C, 7tgn:D
7 6p63:C 595 340 0.1413 0.1311 0.2294 0.001 6p63:A, 6p63:B, 6p63:D, 6xrc:A, 6xrc:B
8 7tgk:D 593 335 0.1322 0.1231 0.2179 0.003 7tgk:B, 7tgk:E, 7tgk:A, 7tgk:C, 7tgl:A, 7tgl:B, 7tgl:C, 7tgl:D, 7tgl:E, 7tgm:A, 7tgm:B, 7tgm:C, 7tgm:E, 7tgm:D
9 2zjs:Y 415 55 0.0362 0.0482 0.3636 0.024
10 8xi9:A 201 48 0.0308 0.0846 0.3542 1.1 1a7x:A, 1a7x:B, 1bkf:A, 1bl4:A, 1bl4:B, 8chi:A, 8chi:B, 8chj:A, 8chj:B, 8chj:C, 8chj:D, 8chk:A, 8chk:B, 8chk:C, 8chl:A, 8chl:B, 8chm:A, 1d7i:A, 1d7i:B, 1d7j:A, 1d7j:B, 2dg3:A, 2dg4:A, 2dg9:A, 4dh0:A, 8er6:A, 8er6:C, 8er6:E, 8er7:A, 8er7:C, 8er7:E, 8era:B, 1f40:A, 1fap:A, 2fap:A, 3fap:A, 4fap:A, 1fkb:A, 1fkd:A, 1fkf:A, 1fkg:A, 1fkh:A, 1fki:A, 1fki:B, 1fkj:A, 1fkl:A, 2fke:A, 1j4h:A, 1j4i:A, 1j4r:A, 1j4r:B, 1j4r:D, 6m4u:A, 6m4u:E, 6m4v:B, 6m4v:D, 6m4w:D, 6m4w:E, 6m4w:F, 1nsg:A, 6oqa:A, 6oqa:B, 6oqa:E, 6oqa:F, 8pdf:A, 8ppz:A, 1qpf:A, 1qpf:D, 1qpl:A, 1qpl:C, 1tco:C, 7u0t:B, 7u8d:A, 7u8d:B, 6vcu:A, 6vcu:C, 6vcu:D, 6vcu:B, 6yf0:A, 6yf1:A, 6yf2:A, 6yf3:A
11 1e5e:A 394 94 0.0435 0.0609 0.2553 1.3 1e5e:B, 1e5f:A, 1e5f:B
12 8rch:A 2036 48 0.0308 0.0083 0.3542 1.5 8rch:B, 8rck:B, 8rcn:B
13 6bcu:A 2204 48 0.0308 0.0077 0.3542 1.8 6bcu:B, 6bcx:A, 6bcx:B, 4drh:B, 4drh:E, 4dri:B, 4drj:B, 8er6:B, 8er6:D, 8er6:F, 8er7:B, 8er7:D, 8er7:F, 8era:A, 9f44:A, 9f44:B, 9f45:A, 9f45:B, 1fap:B, 2fap:B, 3fap:B, 4fap:B, 5flc:B, 5flc:F, 5gpg:B, 4jsp:B, 4jsp:A, 4jsv:B, 4jsv:A, 4jsx:B, 4jsx:A, 4jt5:B, 4jt5:A, 4jt6:B, 4jt6:A, 6m4u:B, 6m4u:F, 6m4w:G, 6m4w:H, 6m4w:I, 1nsg:B, 7pe7:B, 7pe7:A, 7pe8:A, 7pe9:A, 7pea:B, 7pea:A, 7peb:A, 7pec:A, 8ppz:B, 7uxc:A, 7uxh:A, 7uxh:C, 5wbh:C, 5wbh:D, 5wbu:B, 5wbu:A, 6zwo:B
14 6zwm:B 2185 48 0.0308 0.0078 0.3542 1.8 6zwm:A
15 7moa:D 638 120 0.0525 0.0455 0.2417 2.9 1bht:A, 1bht:B, 5cp9:B, 5cs3:B, 5cs5:B, 5ct3:B, 1gmn:B, 1gmn:A, 1gmo:B, 1gmo:H, 1gmo:F, 1gmo:C, 1gmo:G, 1gmo:A, 1gmo:D, 1gmo:E, 6lz9:B, 3mkp:C, 3mkp:A, 7mo7:A, 7mo8:A, 7mo9:A, 7moa:A, 4o3t:A, 4o3u:A
16 8wb4:C 451 74 0.0344 0.0421 0.2568 3.3 8wb4:c, 8xlp:c, 8xlp:C, 8xr6:c, 8xr6:C
17 6qcl:A 215 44 0.0290 0.0744 0.3636 3.5
18 4xnh:A 786 43 0.0254 0.0178 0.3256 3.6 4hnw:A, 6o07:A, 4xpd:A, 4y49:G
19 8pn9:G 411 72 0.0380 0.0511 0.2917 4.8 6s7o:G, 6s7t:G
20 6xig:B 383 128 0.0634 0.0914 0.2734 6.2 6xi9:A, 6xi9:B, 6xig:A
21 6a06:A 188 66 0.0362 0.1064 0.3030 6.5 6a03:A, 6a03:B, 6a04:A, 6a04:B, 6a05:A, 6a05:B, 6a06:B, 6iyf:A, 6iyf:B
22 5v9x:A 772 81 0.0399 0.0285 0.2716 9.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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