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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
TKRKAYTRPQFRRPHTYRRPATVKPSSNVSAIKNKWDAFRIIRYPLTTDKAMKKIEENNTLTFIVDSRANKTEIKKAIRK
LYQVKTVKVNTLIRPDGLKKAYIRLSASYDALDTANKMGLV

The query sequence (length=121) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 4v8m:BX 121 121 1.0000 1.0000 1.0000 2.25e-85 8ova:BX, 8ove:BX, 5t5h:X
2 5t2a:V 120 119 0.8264 0.8333 0.8403 2.65e-69 8a3w:V, 8a98:V, 6az3:V, 3jcs:V, 8ovj:V, 8rxh:LV, 8rxx:LV
3 8ipx:g 145 120 0.5620 0.4690 0.5667 3.60e-42 7a01:m2, 8a3d:R, 5aj0:AX, 8b5l:X, 8b6c:X, 9bdl:AL25, 9bdn:AL25, 9bdp:AL25, 8bf9:X, 7bhp:LX, 8bhf:K1, 8bpo:W2, 8btk:BX, 7cpu:LX, 7cpv:LX, 4d5y:X, 4d67:X, 6d90:X, 6d9j:X, 9f1b:BX, 9f1c:BX, 9f1d:BX, 7f5s:LX, 8fkt:LH, 8fku:LH, 8fkv:LH, 8fkw:LH, 8fkx:LH, 8fky:LH, 8fkz:LH, 8fl2:LH, 8fl3:LH, 8fl4:LH, 8fl6:LH, 8fl7:LH, 8fl9:LH, 8fla:LH, 8flb:LH, 8flc:LH, 8fld:LH, 8fle:LH, 8flf:LH, 9fpz:LX, 9fq0:LX, 6frk:X, 6ftg:X, 6fti:X, 6ftj:X, 8g5y:LX, 8g5z:LX, 8g60:LX, 8g61:LX, 8g6j:LX, 8glp:LX, 6gz3:AX, 6gz4:AX, 6gz5:AX, 6hcf:X3, 6hcj:X3, 6hcm:X3, 6hcq:X3, 8idt:g, 8idy:g, 8ie3:g, 8ifd:2R, 8ife:2R, 8ine:g, 8inf:g, 8ink:g, 6ip5:2R, 6ip6:2R, 6ip8:2R, 8ipd:g, 8ipy:g, 8ir1:g, 8ir3:g, 3j7o:X, 3j7p:X, 3j7q:X, 3j7r:X, 3j92:X, 3jag:X, 3jah:X, 3jai:X, 3jaj:X, 3jan:X, 8jdj:c, 8jdk:c, 8jdl:c, 8jdm:c, 8k2c:LX, 5lks:LX, 6lqm:g, 6lsr:g, 6lss:g, 7ls1:R2, 7ls2:R2, 6lu8:g, 5lzs:X, 5lzt:X, 5lzu:X, 5lzv:X, 5lzw:X, 5lzx:X, 5lzy:X, 5lzz:X, 7mdz:X, 6mtb:X, 6mtc:X, 6mtd:X, 6mte:X, 7nfx:X, 7nwg:X3, 7nwh:X, 7nwi:X, 7o7y:BX, 7o7z:BX, 7o80:BX, 7o81:BX, 7obr:X, 8ohd:LX, 8oj0:LX, 8oj5:LX, 8oj8:LX, 6ole:Y, 6olf:Y, 6olg:AX, 6oli:Y, 6olz:AX, 6om0:Y, 6om7:Y, 8ony:LX, 7ow7:R, 7oya:X1, 7oyb:X1, 7oyc:X1, 7oyd:X, 8p2k:BX, 6p5i:AX, 6p5j:AX, 6p5k:AX, 6p5n:AX, 8q7z:BX, 8q87:BX, 8qfd:X, 7qgg:Y, 8qoi:LX, 7qvp:MX, 7qvp:LX, 7qwq:X, 7qwr:X, 7qws:X, 6qzp:LX, 6r5q:X, 6r6g:X, 6r6p:X, 6r7q:X, 8rjb:X, 8rjc:X, 8rjd:X, 8scb:X, 6sgc:X2, 6swa:V, 6sxo:LX, 5t2c:R, 6t59:X3, 7tm3:X, 7toq:AL25, 7tor:AL25, 7tut:X, 7ucj:X, 7uck:X, 4ug0:LX, 4ujc:BX, 4ujd:AX, 4uje:CX, 4v5z:Bs, 4v6x:CX, 6w6l:Y, 6xa1:LX, 7xnx:LX, 7xny:LX, 8xsx:LX, 8xsy:LX, 8xsz:LX, 6y0g:LX, 8y0w:LX, 8y0x:LX, 6y2l:LX, 6y57:LX, 6y6x:LX, 8yoo:LX, 8yop:LX, 6z6l:LX, 6z6m:LX, 6z6n:LX, 7zjw:La, 7zjx:La, 6zm7:LX, 6zme:LX, 6zmi:LX, 6zmo:LX, 6zvk:m2
4 4v6w:CX 120 119 0.5372 0.5417 0.5462 4.97e-41 6xu6:CX, 6xu7:CX, 6xu8:CX
5 6zj3:Lk 131 121 0.5537 0.5115 0.5537 1.44e-40
6 5xxb:W 127 127 0.5455 0.5197 0.5197 2.22e-39
7 9bh5:CX 119 115 0.4793 0.4874 0.5043 1.39e-34 9cai:CX
8 7btb:X 141 118 0.4545 0.3901 0.4661 1.17e-33 8aaf:K, 8agt:K, 8agu:K, 8agv:K, 8agw:K, 8agx:K, 8agz:K, 5apn:X, 5apo:X, 7azy:I, 7b7d:LT, 8bip:LX, 8bjq:LX, 8bn3:N5, 8bqd:AH, 8bqx:AH, 7bt6:X, 6cb1:X, 8ccs:J, 8cdl:J, 8cdr:J, 8ceh:J, 8cf5:J, 8cg8:J, 8cgn:J, 8civ:J, 8cku:J, 8cmj:J, 5dat:N5, 5dat:n5, 5dc3:N5, 5dc3:n5, 5dge:N5, 5dge:n5, 5dgf:N5, 5dgf:n5, 5dgv:N5, 5dgv:n5, 6elz:X, 6em5:X, 8eub:AX, 8evp:AX, 8evq:AX, 8evr:AX, 8evs:AX, 8evt:AX, 8ewb:AX, 8ewc:AX, 5fci:N5, 5fci:n5, 5fcj:N5, 5fcj:n5, 6ft6:X, 5gak:Z, 6gq1:X, 6gqb:X, 6gqv:X, 5h4p:X, 6hd7:Z, 8hfr:Xc, 6hhq:8, 6hhq:CZ, 5i4l:N5, 5i4l:n5, 6i7o:AH, 6i7o:XH, 5it7:XX, 3j6x:65, 3j6y:65, 3j77:75, 3j78:75, 3jct:X, 5jcs:X, 5juo:CA, 5jup:CA, 5jus:CA, 5jut:CA, 5juu:CA, 8k2d:LX, 8k82:LX, 5lyb:N5, 5lyb:n5, 5m1j:X5, 6m62:X, 5mc6:AH, 5mei:8, 5mei:CZ, 7mpi:AX, 7mpj:AX, 6n8j:X, 6n8k:X, 6n8l:X, 6n8m:k, 6n8n:k, 6n8o:k, 7n8b:AX, 7nac:X, 5ndg:N5, 5ndg:n5, 5ndv:N5, 5ndv:n5, 5ndw:N5, 5ndw:n5, 7nrc:LZ, 7nrd:LZ, 5obm:N5, 5obm:n5, 7of1:X, 7oh3:X, 7ohq:X, 7ohr:X, 7ohv:X, 6oig:X, 5on6:8, 5on6:CZ, 7osa:uL23, 7osm:uL23, 8p8m:QX, 8p8n:QX, 8p8u:QX, 8pfr:QX, 6q8y:AH, 6qik:W, 6qt0:W, 6qtz:W, 7r7a:X, 6r84:Z, 6r86:Z, 6r87:Z, 6ri5:W, 7rr5:LX, 6rzz:W, 6s05:W, 6s47:AZ, 6snt:as, 6sv4:AH, 6sv4:XH, 6sv4:zH, 6t4q:LX, 5t62:k, 5t6r:k, 6t7i:LX, 6t7t:LX, 6t83:Xy, 6t83:I, 5tbw:8, 5tbw:CZ, 6tb3:AH, 5tga:N5, 5tga:n5, 5tgm:N5, 5tgm:n5, 6tnu:AH, 7too:AL25, 7top:AL25, 7u0h:X, 4u3m:N5, 4u3m:n5, 4u3n:N5, 4u3n:n5, 4u3u:N5, 4u3u:n5, 4u4n:N5, 4u4n:n5, 4u4o:N5, 4u4o:n5, 4u4q:N5, 4u4q:n5, 4u4r:N5, 4u4r:n5, 4u4u:N5, 4u4u:n5, 4u4y:N5, 4u4y:n5, 4u4z:N5, 4u4z:n5, 4u50:N5, 4u50:n5, 4u51:N5, 4u51:n5, 4u52:N5, 4u52:n5, 4u53:N5, 4u53:n5, 4u55:N5, 4u55:n5, 4u56:N5, 4u56:n5, 4u6f:N5, 4u6f:n5, 7ug6:X, 7uoo:X, 7uqb:X, 7uqz:X, 6uz7:AX, 7v08:X, 4v4b:BT, 4v6i:BX, 4v7f:W, 4v7h:BT, 4v7r:BW, 4v7r:DW, 4v88:BX, 4v88:DX, 4v8t:X, 4v8y:BX, 4v8z:BX, 8v87:X, 4v91:X, 6woo:X, 2ww9:K, 2wwa:K, 2wwb:K, 6xiq:X, 6xir:X, 8y0u:LX, 6ylg:X, 6ylh:X, 6ylx:X, 6yly:X, 7z34:X, 6z6j:LX, 6z6k:LX, 7zpq:BW, 7zrs:BW, 7zs5:BY, 7zuw:BW, 7zux:EW, 7zw0:La
9 8pv1:LX 145 124 0.4959 0.4138 0.4839 3.27e-32 8i9w:LX, 8i9x:LX, 8i9y:LX, 8i9z:LX, 8ia0:LX, 7olc:LX, 7old:LX, 8onz:LX, 8oo0:LX, 8pv2:LX, 8pv3:LX, 8pv4:LX, 8pv5:LX, 8pv6:LX, 8pv7:LX, 8pv8:LX, 8pvk:LX, 8pvl:LX, 7r81:Z1, 7z3n:LX, 7z3o:LX
10 4v3p:LX 122 112 0.5124 0.5082 0.5536 1.13e-31 8azw:k, 8b2l:k3, 8ip8:NA, 8ipa:NA, 8ipb:NA, 2j37:4, 8jiv:CX, 7qiw:Z, 7qiz:Z, 4v7e:CX
11 8c3a:8 121 118 0.4628 0.4628 0.4746 3.27e-31 8c3a:BS, 8cq7:8, 8cq7:BS, 8cqw:8, 8cqw:BS, 8cre:8, 8cre:BS, 8oeq:8, 8oeq:BS, 7pzy:8, 7q08:8, 7q0f:8, 7q0p:8, 7q0r:8, 8q5i:8
12 8esq:X 132 111 0.4545 0.4167 0.4955 3.89e-31 8esr:X, 8etc:X, 8etg:X, 8eti:X, 8eug:X, 8eui:X
13 7nad:X 98 83 0.3719 0.4592 0.5422 3.98e-30 7r72:X
14 3j79:Y 101 84 0.3802 0.4554 0.5476 2.14e-28 3jbn:AY, 3jbo:AY, 3jbp:AY, 8tpu:AY, 5umd:Y
15 8brm:LY 119 120 0.4463 0.4538 0.4500 3.82e-27 8br8:LY, 8bsi:LY, 8bsj:LY, 8btd:LY, 8btr:LY, 8fru:X, 7pwg:X, 7pwo:X2
16 4v8p:BR 121 121 0.4628 0.4628 0.4628 1.09e-26 4v8p:CR, 4v8p:ER, 4v8p:GR
17 6skf:BW 85 85 0.3388 0.4824 0.4824 6.38e-23 6skg:BW, 6th6:BW
18 5xy3:X 101 106 0.4215 0.5050 0.4811 1.46e-22
19 5mmi:U 96 85 0.3388 0.4271 0.4824 1.73e-22 6eri:AT, 5h1s:V, 5mlc:V, 5mmm:U, 4v61:BV, 5x8p:U, 5x8t:U
20 4v4n:AT 84 82 0.3306 0.4762 0.4878 2.83e-22 4v6u:BT
21 8hku:L23P 81 81 0.3306 0.4938 0.4938 2.51e-20 8hkv:L23P, 8hky:L23P, 8hkz:L23P, 8hl1:L23P, 8hl2:L23P, 8hl3:L23P, 8hl4:L23P, 8hl5:L23P
22 6zu5:LX0 98 105 0.3388 0.4184 0.3905 4.33e-17
23 1w2b:R 84 85 0.2893 0.4167 0.4118 6.46e-17 3cc2:S, 3cc4:S, 3cc7:S, 3cce:S, 3ccj:S, 3ccl:S, 3ccm:S, 3ccq:S, 3ccr:S, 3ccs:S, 3ccu:S, 3ccv:S, 3cd6:S, 3cma:S, 3cme:S, 3cpw:R, 3cxc:R, 3g4s:S, 3g6e:S, 3g71:S, 3i55:S, 3i56:S, 1jj2:R, 1k73:T, 1k8a:T, 1k9m:T, 1kc8:T, 1kd1:T, 1kqs:R, 1m1k:T, 1m90:T, 1n8r:T, 1nji:T, 2otj:S, 2otl:S, 3ow2:R, 1q7y:T, 1q81:T, 1q82:T, 1q86:T, 2qa4:S, 2qex:S, 1qvf:R, 1qvg:R, 1s72:S, 4v4p:AT, 4v4r:BX, 4v4s:BX, 4v4t:BX, 4v9f:S, 1vq4:S, 1vq5:S, 1vq6:S, 1vq7:S, 1vq8:S, 1vq9:S, 1vqk:S, 1vql:S, 1vqm:S, 1vqn:S, 1vqo:S, 1vqp:S, 1yhq:S, 1yi2:S, 1yij:S, 1yit:S, 1yj9:S, 1yjn:S, 1yjw:S
24 6rm3:LX0 93 79 0.2975 0.3871 0.4557 6.39e-16
25 7qep:N5 93 79 0.3223 0.4194 0.4937 1.71e-15
26 8p5d:LX0 112 86 0.3058 0.3304 0.4302 2.56e-15 8p60:LX0, 8p60:KX0, 7qca:LX0
27 7jil:T 85 57 0.2231 0.3176 0.4737 2.35e-09
28 6yhs:P 92 85 0.2479 0.3261 0.3529 4.28e-08 7m4v:S, 7m4w:S, 7m4x:S, 7m4y:S, 7m4z:S, 7ryf:S, 7ryg:S, 7ryh:S, 7uvv:S, 7uvw:S, 7uvx:S, 7uvy:S, 7uvz:S, 7uw1:S, 6v39:S, 6v3a:S, 6v3b:S, 6v3d:S, 6ysi:P
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30 3j45:T 100 72 0.1983 0.2400 0.3333 2.28e-07 5aka:T, 3bbx:T, 8c9a:T, 2j28:T, 3j46:T, 3j9z:LR, 3ja1:LV, 6o9j:T, 4v4h:BT, 4v4h:DT, 4v4q:BT, 4v4q:DT, 4v5b:AT, 4v5b:CT, 4v65:BM, 4v66:BM, 4v6k:AU, 4v6l:BU, 4v6m:BT, 4v6n:AV, 4v6o:BV, 4v6p:BV, 4v6q:BV, 4v6r:BV, 4v6s:AV, 4v6v:BX, 7zq5:t, 7zq6:t
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32 9c4g:s 95 54 0.1983 0.2526 0.4444 1.48e-06 8crx:s, 8cvm:s
33 5myj:BW 88 81 0.2314 0.3182 0.3457 1.51e-06
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35 7ood:s 92 86 0.2149 0.2826 0.3023 2.49e-06 7p6z:s, 7pah:s, 7pai:s, 7paj:s, 7pak:s, 7pal:s, 7pam:s, 7pan:s, 7pao:s, 7paq:s, 7par:s, 7pas:s, 7pat:s, 7pau:s, 7ph9:s, 7pha:s, 7phb:s, 7phc:s, 7pi8:s, 7pi9:s, 7pia:s, 7pib:s, 7pic:s, 7pio:s, 7pip:s, 7piq:s, 7pir:s, 7pis:s, 7pit:s
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37 6dzi:U 97 51 0.1901 0.2371 0.4510 1.06e-05 6dzp:U, 8fr8:Z, 8kab:U, 5o60:U, 5o61:U, 7s0s:V, 8v9j:V, 8v9k:V, 8v9l:V, 8whx:W, 8why:W, 8wi7:W, 8wi8:W, 8wib:W, 8wic:W, 7xam:U, 5xym:T, 8xz3:U, 7y41:U, 5zeb:U, 5zep:U, 5zet:U
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39 8fmw:AV 98 55 0.1818 0.2245 0.4000 3.28e-05 8fn2:V
40 3j3v:T 95 52 0.1653 0.2105 0.3846 8.13e-05 7aqc:h, 7aqd:h, 7as8:X, 7as9:X, 8buu:T, 6ha1:T, 6ha8:T, 6htq:T, 3j3w:T, 3j9w:BW, 5njt:m, 7o5b:s, 7ope:X, 6ppf:T, 6ppk:T, 6pvk:T, 8qcq:T, 7qgu:T, 7qh4:T, 8qpp:s, 7qv1:T, 7qv2:T, 7qv3:T, 8r55:s, 8s1p:T, 8s1u:T, 7s9u:T, 7sae:T, 6tnn:m, 6tpq:m
41 8rd8:Sn 88 83 0.2066 0.2841 0.3012 9.09e-05 8rdv:Sn, 8rdw:Sn
42 7f0d:T 98 51 0.1653 0.2041 0.3922 1.08e-04 7kgb:T, 7msc:T, 7msh:T, 7msm:T, 7msz:T, 7mt2:T, 7mt3:T, 7mt7:T, 7sfr:T, 5v7q:T, 5v93:T
43 6spf:T 94 90 0.2397 0.3085 0.3222 2.29e-04 8cd1:T, 6spb:T, 6spd:T, 6spg:T, 7unr:V, 7unu:V, 7unv:V, 7unw:V
44 6z1p:Ax 132 48 0.1570 0.1439 0.3958 0.015
45 7r6q:X 62 25 0.1157 0.2258 0.5600 0.017
46 8psn:A 417 94 0.2066 0.0600 0.2660 0.54 8pso:A, 8psq:A, 8pss:A, 8psu:A, 8psx:A, 8psz:A, 8pt2:A, 8pt6:A, 8pt7:A, 8pth:A, 8ptj:A, 8qz8:A
47 6hiv:CF 159 46 0.1322 0.1006 0.3478 2.1 6hiw:CF, 6hiy:CF, 7pua:CF, 7pub:CF, 6sga:CF, 6sgb:CF
48 8ip8:QA 142 47 0.1488 0.1268 0.3830 2.9 8ipa:QA, 8ipb:QA, 8jiv:Cr
49 6xyw:At 105 32 0.1322 0.1524 0.5000 3.2
50 2gqt:A 267 49 0.1074 0.0487 0.2653 6.5 2gqu:A
51 7obq:v 201 55 0.1322 0.0796 0.2909 6.8 2fh5:B, 6frk:v, 7nfx:v
52 5zwx:A 148 67 0.1653 0.1351 0.2985 8.7 5zwx:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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