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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGG

The query sequence (length=34) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3avt:A 1203 34 1.0000 0.0283 1.0000 7.10e-18 7abz:6, 5afi:z, 3agp:A, 3agq:A, 3avu:A, 3avv:A, 3avw:A, 3avx:A, 3avy:A, 7bbn:A, 7bbn:B, 2bvn:A, 2bvn:B, 1efm:A, 1etu:A, 4fwt:A, 2hcj:A, 2hcj:B, 2hdn:A, 2hdn:B, 2hdn:C, 2hdn:D, 2hdn:E, 2hdn:F, 2hdn:G, 2hdn:H, 2hdn:I, 2hdn:J, 2hdn:K, 2hdn:L, 5i4r:C, 5i4r:D, 5i4r:G, 5i4r:H, 3mmp:G, 5opd:A, 5opd:B, 4pc2:A, 4pc2:B, 4pc3:A, 4pc3:B, 4pc6:A, 4pc6:B, 4pc7:A, 3u6b:B, 3u6b:A, 3vnu:A, 3vnv:A, 6wd4:8, 6wd7:8, 6wd9:8, 6wda:8
2 1ob2:A 393 34 1.0000 0.0865 1.0000 2.27e-16 1d8t:A, 1d8t:B, 1dg1:G, 1dg1:H, 1efc:A, 1efc:B, 6eze:A, 6eze:B, 8fr3:A, 8fr3:B, 2fx3:A, 4g5g:A, 8g7p:z, 8g7q:z, 5jbq:A, 5mi3:A, 5mi3:B, 5mi8:A, 5mi8:B, 5mi9:A, 5mi9:B, 4p3y:A, 8qfs:C, 8qhc:C, 3u2q:A, 3u6k:A, 3u6k:B, 5uyk:Z, 5uyl:Z, 5uym:Z, 5uyn:Z, 5uyp:Z, 5uyq:Z, 4v69:AZ, 4v6k:BC, 4v6l:AC, 5wdt:z, 6wd2:8, 6wd3:8, 6wd5:8, 6wd6:8, 6wd8:8, 5we4:z, 5we6:z, 5wf0:z, 5wfk:z, 5wfs:z
3 6mij:A 388 33 0.8824 0.0773 0.9091 2.52e-14
4 4zv4:A 392 33 0.7941 0.0689 0.8182 1.60e-12 4zv4:B
5 7paj:9 393 30 0.7941 0.0687 0.9000 2.19e-12 7pak:9, 7pha:9, 7pi9:9, 7pip:9
6 6gfu:A 386 33 0.8235 0.0725 0.8485 2.77e-12 5w76:A, 5w7q:A
7 1d2e:A 397 29 0.7647 0.0655 0.8966 1.52e-11 7a5g:Z, 1d2e:B, 1d2e:C, 1d2e:D, 7o9k:t
8 4iw3:B 380 31 0.7059 0.0632 0.7742 5.65e-11 4iw3:K, 4j0q:A, 4j0q:B, 4j0q:C, 4j0q:D, 4j0q:E
9 8v9l:x 387 31 0.7353 0.0646 0.8065 6.29e-11 7vok:A, 7vok:B, 7vok:C, 7vok:D
10 7vmx:B 359 31 0.7353 0.0696 0.8065 8.74e-11
11 5w75:C 387 29 0.7353 0.0646 0.8621 9.58e-11 5w75:B, 5w75:D, 5w75:A
12 4v5p:AZ 385 29 0.7647 0.0675 0.8966 1.10e-10 1ha3:B, 4v5g:AZ, 4v5g:CZ, 4v5p:CZ, 4v5q:AZ, 4v5q:CZ, 4v5r:AZ, 4v5r:CZ, 4v5s:AZ, 4v5s:CZ, 4v68:AZ
13 1b23:P 405 29 0.7647 0.0642 0.8966 1.11e-10 2c77:A, 2c78:A, 1eft:A, 1exm:A, 4h9g:A, 1ha3:A, 4lbv:A, 4lbw:A, 4lby:A, 4lbz:A, 4lc0:A, 1mj1:A, 1ob5:A, 1ob5:C, 1ob5:E, 2p8w:S, 2p8x:S, 2p8z:S, 1ttt:A, 1ttt:B, 1ttt:C, 1tui:A, 1tui:B, 1tui:C, 4v5l:AZ, 4v8q:BZ
14 6htw:B 385 28 0.7353 0.0649 0.8929 1.20e-10 6htw:H, 6i8r:A
15 3qsy:A 415 26 0.5000 0.0410 0.6538 4.19e-07 2aho:A, 3cw2:B, 6i5m:A, 5jb3:7, 5jbh:7, 4m0l:A, 4m0l:B, 4m0l:C, 4m0l:D, 4m0l:E, 4m0l:F, 4m2l:A, 4m4s:A, 4nbs:A, 3pen:A, 2pmd:A, 2pmd:B, 4qfm:A, 4qhy:A, 2qmu:A, 2qn6:A, 6r8s:A, 6r8t:A, 4rcy:A, 4rcz:A, 4rd0:A, 4rd1:A, 4rd2:A, 4rd3:A, 4rd4:A, 4rd6:A, 4rjl:A, 3sjz:A, 6sw9:7, 6swc:7, 3v11:A
16 2dcu:A 407 29 0.5294 0.0442 0.6207 6.18e-06 2d74:A, 1kjz:A, 1kk0:A, 1kk1:A, 1kk2:A, 1kk3:A
17 1s0u:A 391 27 0.4706 0.0409 0.5926 2.20e-05
18 8rdw:H 386 15 0.4412 0.0389 1.0000 1.11e-04 8rd8:H
19 6ji2:A 432 21 0.4118 0.0324 0.6667 1.52e-04 4cxg:A, 4cxh:A, 6ji2:E, 3vmf:A, 3wxm:A, 3wxm:C, 3wxm:E, 3wxm:G
20 1skq:A 416 23 0.4118 0.0337 0.6087 2.75e-04 1jny:A, 1jny:B, 1skq:B
21 5lzb:z 614 23 0.4706 0.0261 0.6957 2.80e-04 5lzc:z, 5lzd:z, 2pjp:A
22 8qzz:A 433 26 0.4412 0.0346 0.5769 2.81e-04 7a09:Y, 6zp4:Y
23 8rw1:k 470 23 0.4118 0.0298 0.6087 3.09e-04 6fyx:k, 6gsm:k, 6gsn:k, 6qg0:M, 6qg0:N, 6qg1:M, 6qg1:N, 6qg2:M, 6qg3:M, 6qg5:M, 6qg6:M, 6qg6:N, 8s8d:k, 8s8e:k, 8s8g:k, 8s8h:k, 8s8i:k, 8s8j:k
24 3j81:k 365 23 0.4118 0.0384 0.6087 3.16e-04
25 8cas:G 396 23 0.4118 0.0354 0.6087 3.63e-04 6fyy:k, 6i3m:O, 6i3m:P, 6i7t:O, 6i7t:P, 3jap:k, 8s8f:k
26 4ac9:C 471 31 0.4118 0.0297 0.4516 3.96e-04 4ac9:A, 4ac9:B, 4aca:B, 4aca:C, 4acb:A, 4acb:B, 4acb:C
27 7qp6:t 356 23 0.4118 0.0393 0.6087 4.83e-04 7qp7:t, 6ybv:t, 6zmw:t
28 3wy9:A 416 18 0.4118 0.0337 0.7778 5.60e-04 3wy9:B, 3wya:A
29 7ase:5 421 28 0.4412 0.0356 0.5357 7.75e-04
30 7zjw:E 519 24 0.3824 0.0250 0.5417 0.001 5izl:A, 5izl:B
31 5izk:B 451 23 0.3824 0.0288 0.5652 0.001
32 5fg3:A 598 30 0.5294 0.0301 0.6000 0.001 5yt0:A
33 5izm:B 495 28 0.4118 0.0283 0.5000 0.002 5izk:A, 5izm:A
34 7yyp:A 597 30 0.5000 0.0285 0.5667 0.002 7yzn:A, 7zag:7, 7zah:7, 7zki:7
35 8pj1:t 472 23 0.4118 0.0297 0.6087 0.002 7d43:P, 6fec:S, 5k0y:S, 6k71:P, 6k72:P, 8oz0:E, 8pj2:t, 8ppl:It, 6yal:B, 6yam:B, 6yan:B
36 7old:C 813 26 0.3529 0.0148 0.4615 0.005
37 3j9y:w 639 20 0.3235 0.0172 0.5500 0.008 5kcs:1w
38 4zu9:A 582 20 0.3529 0.0206 0.6000 0.009
39 6u45:A 726 16 0.2941 0.0138 0.6250 0.010 6u43:A, 6u44:A, 6u44:B, 6u45:B
40 5lzt:jj 428 23 0.4118 0.0327 0.6087 0.011 4d61:i, 5hxb:X, 5hxb:A, 7nwh:jj, 6xk9:X, 6xk9:A
41 4v6w:Az 837 21 0.3235 0.0131 0.5238 0.012
42 8hl1:AEFG 725 16 0.3235 0.0152 0.6875 0.013 8hl2:AEFG, 8hl3:AEFG, 8hl4:AEFG
43 1r5o:A 409 23 0.4118 0.0342 0.6087 0.014 1r5n:A
44 4v6v:A1 639 20 0.3235 0.0172 0.5500 0.017
45 8q87:A 857 19 0.3235 0.0128 0.5789 0.019 6d9j:9, 6gz3:Ct, 6gz4:Ct, 6gz5:Ct, 3j7p:4, 7ls1:m, 7ls2:m, 6mtd:v, 6mte:v, 7oyc:v2, 4v6x:Az, 8xsx:CB, 6z6m:CB, 6z6n:CB
46 8y0w:CB 768 19 0.3235 0.0143 0.5789 0.019 8y0x:CB
47 7oyd:v 726 19 0.3235 0.0152 0.5789 0.019
48 5h7l:A 694 16 0.2941 0.0144 0.6250 0.026 5h7k:A, 5h7l:B
49 8cf5:Aa 842 19 0.3235 0.0131 0.5789 0.028 8cdr:Aa, 8ceh:Aa, 8cg8:Aa, 8civ:Aa, 8cku:Aa, 8cmj:Aa, 2e1r:A, 8eub:DC, 8evq:DC, 8evr:DC, 8evs:DC, 8ewb:DC, 6gq1:AZ, 6gqb:AZ, 6gqv:AX, 5it7:1, 5juo:DC, 5jup:DC, 5jus:DC, 5jut:DC, 5juu:DC, 8k2d:CD, 1n0u:A, 2npf:A, 2npf:B, 7osa:eEF2, 7osm:eEF2, 2p8w:T, 2p8x:T, 2p8y:T, 2p8z:T, 1u2r:A, 4v4b:AT, 1zm2:E
50 3jce:x 586 25 0.3235 0.0188 0.4400 0.033 3deg:C
51 8bsi:a 815 19 0.3235 0.0135 0.5789 0.034
52 5aa0:BZ 605 15 0.3235 0.0182 0.7333 0.036 5a9z:CA, 4zck:A, 4zcl:A, 4zcl:B, 4zcm:A, 4zcm:B
53 5a9y:A 562 15 0.3235 0.0196 0.7333 0.036 5a9x:A
54 5o8w:A 449 20 0.3824 0.0290 0.6500 0.049 2b7b:A, 9bdp:EF1A, 1g7c:A, 1ije:A, 1ijf:A
55 1g7s:A 576 14 0.3235 0.0191 0.7857 0.053 1g7t:A
56 7pua:IA 704 30 0.4412 0.0213 0.5000 0.069 7pub:IA
57 3izy:P 537 30 0.4706 0.0298 0.5333 0.079
58 2lkd:A 178 23 0.4412 0.0843 0.6522 0.083
59 6ra9:B 458 20 0.3529 0.0262 0.6000 0.11 8b6z:A, 4c0s:A, 4c0s:B, 8g5z:EF, 8g60:EF, 8g6j:EF, 5lzs:jj, 6ra9:A, 6zmo:CD
60 5anb:K 1120 15 0.2941 0.0089 0.6667 0.11 5anc:K
61 6gaw:BC 571 30 0.4706 0.0280 0.5333 0.12 6gaz:BC, 6gb2:BC, 7po2:7, 8qrn:7, 6rw5:7
62 5lmv:a 502 19 0.3824 0.0259 0.6842 0.12
63 4kjz:C 458 19 0.3824 0.0284 0.6842 0.12 4b43:A, 4b44:A, 4b47:A, 4b48:A, 4kjz:A
64 5m1j:A6 539 18 0.2941 0.0186 0.5556 0.12
65 3p27:B 444 18 0.2941 0.0225 0.5556 0.12 3p27:A
66 5j8b:z 671 19 0.3235 0.0164 0.5789 0.20 5imq:B
67 6vlz:v 712 19 0.2941 0.0140 0.5263 0.21 7a5k:r1, 6vmi:v, 6ydp:BC, 6ydw:BC
68 4w2e:y 644 19 0.3235 0.0171 0.5789 0.22
69 8ro0:C 898 20 0.3235 0.0122 0.5500 0.22 8ro1:C
70 5imr:C 570 19 0.3235 0.0193 0.5789 0.24
71 7nsh:BC 700 19 0.2941 0.0143 0.5263 0.28 7l20:w
72 8sq0:A 1402 32 0.3235 0.0078 0.3438 0.47 8sq0:B, 8sql:A, 8sqm:A
73 9ax8:z 509 36 0.5294 0.0354 0.5000 0.49 3jcj:f, 3jcn:b, 5me0:W, 5me1:W, 6o7k:f, 6o9k:z
74 4hi0:E 196 28 0.3529 0.0612 0.4286 0.51 4hi0:F
75 7unv:x 593 14 0.2941 0.0169 0.7143 0.52 7unq:x, 7unr:x, 7unt:x, 7unu:x, 7unw:x
76 8p2f:E 670 19 0.2941 0.0149 0.5263 0.55 8p2g:E, 8p2h:E
77 2ywf:A 532 15 0.2941 0.0188 0.6667 0.57 2ywg:A, 2ywh:A
78 4v02:A 244 26 0.4706 0.0656 0.6154 0.82 4v02:B, 4v03:A, 4v03:B
79 7pjx:x 522 26 0.3529 0.0230 0.4615 0.86
80 3kxi:A 326 28 0.2647 0.0276 0.3214 0.90 2qth:A
81 5hau:1z 730 19 0.2941 0.0137 0.5263 0.95 2bm0:A, 2bm1:A, 1fnm:A, 6gzq:H1, 6gzx:H1, 6gzx:H2, 6gzz:H1, 6gzz:H2, 5hau:2z, 4m1k:A, 4myt:A, 4myu:A, 2om7:L, 5ot7:U, 6q95:G, 6ucq:1v, 6ucq:2v, 4v5f:AY, 4v5f:CY, 4v5m:AY, 4v5n:AY, 4v6t:AY, 4v8u:AY, 4v8u:CY, 4v90:AY, 4v9j:AY, 4v9j:CY, 4v9k:AY, 4v9k:CY, 4v9l:AY, 4v9l:CY, 4v9m:AY, 4v9m:CY, 4w29:AY, 4w29:CY, 4wpo:BZ, 4wpo:DZ, 4wqf:BZ, 4wqf:DZ, 4wqu:BZ, 4wqu:DZ, 4wqy:BZ, 4wqy:DZ
82 4fn5:A 670 19 0.2941 0.0149 0.5263 0.98
83 4v9h:AY 622 19 0.2941 0.0161 0.5263 1.0
84 1efg:A 592 19 0.2941 0.0169 0.5263 1.4 2efg:A
85 2bv3:A 632 19 0.2941 0.0158 0.5263 1.5 1dar:A
86 7n2v:EF 704 19 0.2941 0.0142 0.5263 1.5 3j9z:S1, 3ja1:S3, 7k51:8, 7k52:8, 7k54:8, 7k55:8, 7n2c:EF, 7otc:w, 7pjv:x, 7pjw:x, 7pjy:x, 7pjz:x, 7ss9:8, 7ssd:8, 7ssl:8, 7st7:8, 7ug7:EF, 4v7b:AY, 4v7d:BZ, 4v9o:BV, 4v9o:DV, 4v9o:FV, 4v9o:HV, 4v9p:BV, 4v9p:DV, 4v9p:FV, 4v9p:HV
87 4ncl:B 435 29 0.3824 0.0299 0.4483 1.5 4ncl:A, 4ncn:A, 4ncn:B, 4tmt:A, 4tmt:B, 4tmv:B, 4tmv:A, 4tmw:A, 4tmw:B, 4tmx:A, 4tmx:B, 4tmz:B, 4tmz:A, 4tn1:B, 4tn1:A
88 4crn:P 430 19 0.2941 0.0233 0.5263 1.6
89 2dy1:A 660 18 0.2941 0.0152 0.5556 1.7 1wdt:A
90 7cdw:A 683 19 0.2941 0.0146 0.5263 1.7 7cdw:B
91 5lzw:jj 425 24 0.3235 0.0259 0.4583 1.7 5lzx:jj, 5lzy:jj, 5lzz:jj
92 5ty0:A 378 23 0.3235 0.0291 0.4783 1.8
93 7pao:9 682 19 0.2647 0.0132 0.4737 2.3 7paq:9, 7par:9, 7pib:9, 7pis:9, 7pit:9
94 6yuf:C 456 30 0.3824 0.0285 0.4333 3.4
95 6pgw:A 427 27 0.2941 0.0234 0.3704 4.1 5co1:A, 5co1:B, 5co1:C, 5co1:D
96 5lj3:C 882 16 0.2647 0.0102 0.5625 5.8 6exn:C, 5gam:C, 5gan:C, 5lj5:C, 5lqw:B, 5mps:C, 5mq0:C, 5nrl:C
97 6j6g:C 920 16 0.2647 0.0098 0.5625 5.8 7b9v:C, 6bk8:B, 7dco:C, 5gm6:C, 5gmk:C, 6j6h:C, 6j6n:C, 6j6q:C, 3jcm:H, 6teo:A, 6teo:C, 5wsg:C, 5y88:C, 5ylz:C, 5zwm:C, 5zwo:C
98 5j4y:A 363 14 0.2647 0.0248 0.6429 6.5 5j40:A, 5j47:A, 5j4v:A
99 4gdf:A 497 14 0.2647 0.0181 0.6429 6.5 5d9i:A, 5d9i:B, 4e2i:A, 4e2i:B, 4e2i:C, 4e2i:D, 4e2i:E, 4e2i:F, 4e2i:G, 4e2i:H, 4e2i:I, 4e2i:J, 4e2i:K, 4e2i:L, 4fgn:A, 4fgn:B, 4gdf:B, 4gdf:E, 4gdf:F, 2h1l:A, 2h1l:B, 2h1l:C, 2h1l:D, 2h1l:E, 2h1l:F, 2h1l:G, 2h1l:H, 2h1l:I, 2h1l:J, 2h1l:K, 2h1l:L, 2itl:A, 2itl:B, 1n25:A, 1n25:B, 2nl8:A, 2ntc:A, 2ntc:B, 1svl:A, 1svl:B, 1svl:C, 1svm:A, 1svm:F, 1svm:B, 1svm:C, 1svm:D, 1svm:E, 1svo:A, 1svo:B
100 8bmp:B 281 27 0.2647 0.0320 0.3333 7.8 8bmq:B, 8bms:B, 5d3m:B, 5d3m:F
101 4lqy:A 379 11 0.2353 0.0211 0.7273 8.0 4lr2:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218