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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TKLGINGFGRIGRLVFRAAFGRKDIEVVAINDPFMDLNHLCYLLKYDSVHGQFPCEVTHADGFLLIGEKKVSVFAEKDPS
QIPWGKCQVDVVCESTGVFLTKELASSHLKGGAKKVIMSAPPKDDTPIYVMGINHHQYDTKQLIVSNASCTTNCLAPLAK
VINDRFGIVEGLMTTVHASTANQLVVDGPSKGGKDWRAGRCALSNIIPASTGAAKAVGKVLPELNGKLTGVAFRVPIGTV
SVVDLVCRLQKPAKYEEVALEIKKAAEGPLKGILGYTEDEVVSQDFVHDNRSSIFDMKAGLALNDNFFKLVSWYDNEWGY
SNRVLDLAVHITT

The query sequence (length=333) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1ywg:O 337 332 0.9970 0.9852 1.0000 0.0 2b4r:O, 2b4r:P, 2b4r:Q, 2b4r:R, 2b4t:O, 2b4t:P, 2b4t:Q, 2b4t:R, 1ywg:P, 1ywg:Q, 1ywg:R
2 3sth:C 340 332 0.6997 0.6853 0.7018 6.71e-174 3sth:A, 3sth:B, 3sth:D
3 3cif:A 338 332 0.6727 0.6627 0.6747 4.35e-165 3cif:B, 3cif:C, 3cif:D, 3cps:A, 3cps:B, 8pvf:A, 1vsv:A, 1vsv:B, 1vsv:C, 1vsv:D
4 6m61:O 336 332 0.6456 0.6399 0.6476 1.29e-159 6ade:A, 5ddi:P, 5ddi:R, 5ddi:S, 6iq6:A, 6iq6:B, 6iq6:C, 6iq6:D, 6iq6:E, 1j0x:P, 1j0x:R, 6lgj:A, 6lgj:B, 6lgj:C, 6lgj:D, 6lgk:A, 6lgk:B, 6lgk:C, 6lgm:A, 6lgm:B, 6lgm:C, 6m61:Q, 6m61:P, 4o59:O, 4o59:P, 4o59:R, 4o59:Q, 4o63:P, 4o63:Q, 4o63:R, 8p5f:AAA, 8p5f:DDD, 8p5f:EEE, 8p5f:GGG, 5tso:P, 5tso:R, 5tso:S, 7u5m:A, 7u5m:B, 7u5m:C, 7u5m:D, 1u8f:P, 1u8f:Q, 1u8f:R, 4wnc:O, 4wnc:E, 4wnc:A, 4wnc:B, 4wnc:C, 4wnc:D, 4wni:O, 4wni:A, 4wni:B, 1znq:O, 1znq:P, 1znq:R, 1znq:Q
5 6qun:O 334 333 0.6547 0.6527 0.6547 6.83e-156 6qun:R, 6quq:O, 6quq:R, 4z0h:O, 4z0h:R
6 4mvj:B 332 331 0.6456 0.6476 0.6495 3.78e-155 1dc4:A, 1dc4:B, 1dc6:A, 1dc6:B, 1gad:O, 1gad:P, 1gae:O, 1gae:P, 6io6:A, 4mvj:A, 4mvj:C, 4mvj:D, 4mvj:E, 4mvj:F, 4mvj:G, 4mvj:I, 4mvj:J, 4mvj:K, 4mvj:L, 4mvj:M, 4mvj:O, 4mvj:P, 6utm:A, 6utm:B, 6utn:A, 6utn:B, 6uto:A, 6uto:B, 2vyn:A, 2vyn:B, 2vyn:C, 2vyv:A, 2vyv:B, 2vyv:C, 5za0:A
7 3gpd:R 334 332 0.6276 0.6257 0.6295 5.43e-154 3gpd:G
8 7xzg:A 334 330 0.6306 0.6287 0.6364 1.77e-151 7xzg:B, 7xzg:C, 7xzg:D
9 3e5r:O 336 336 0.6306 0.6250 0.6250 6.39e-151 3e5r:A, 3e5r:B, 3e5r:C, 3v1y:O, 3v1y:A, 3v1y:B, 3v1y:C
10 4p8r:A 331 331 0.6126 0.6163 0.6163 1.30e-150 4p8r:B, 4p8r:C, 4p8r:D
11 8de5:A 338 331 0.6126 0.6036 0.6163 1.64e-150
12 4lsm:A 331 331 0.6096 0.6133 0.6133 7.73e-150 4lsm:B
13 4k9d:A 338 337 0.6246 0.6154 0.6172 8.98e-147 4k9d:B, 4k9d:C, 4k9d:D, 4k9d:E, 4k9d:F, 4k9d:G, 4k9d:H
14 6nlx:C 335 329 0.5886 0.5851 0.5957 9.06e-146 6nlx:B, 6nlx:D, 5ur0:A, 5ur0:B, 5ur0:C, 5ur0:D
15 1dss:G 333 331 0.6096 0.6096 0.6133 5.13e-145 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
16 6px2:A 332 333 0.6276 0.6295 0.6276 2.10e-144 6px2:B, 6px2:C, 6px2:D, 6px2:E, 6px2:F, 6px2:G, 6px2:H
17 3pym:A 332 330 0.5856 0.5873 0.5909 4.76e-144 3pym:B
18 2vyn:D 334 327 0.6036 0.6018 0.6147 1.28e-143 2vyv:D
19 3h9e:P 337 326 0.5946 0.5875 0.6074 5.09e-141 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
20 6m5x:O 334 331 0.5736 0.5719 0.5770 9.55e-137 6m5x:R, 6m5x:P, 6m5x:Q
21 6ok4:A 334 331 0.5826 0.5808 0.5861 1.21e-136 6ok4:B, 6ok4:C, 6ok4:D, 6wyc:A, 6wyc:B, 6wyc:C, 6wyc:D, 6x2e:A, 6x2e:C, 6x2e:D
22 8oha:B 336 333 0.5856 0.5804 0.5856 1.92e-134 8oha:A, 8oha:C, 8oha:D, 8oha:E, 8oha:F, 8oha:G, 8oha:H
23 2i5p:O 309 329 0.5495 0.5922 0.5562 3.42e-129 2i5p:P
24 3cmc:O 334 333 0.5405 0.5389 0.5405 9.54e-121 3cmc:P, 3cmc:Q, 3cmc:R, 1dbv:O, 1dbv:P, 1dbv:Q, 1dbv:R, 2dbv:O, 2dbv:P, 2dbv:Q, 2dbv:R, 3dbv:O, 3dbv:P, 3dbv:Q, 3dbv:R, 4dbv:O, 4dbv:P, 4dbv:Q, 4dbv:R, 1gd1:O, 1gd1:P, 1gd1:Q, 1gd1:R, 1npt:O, 1npt:P, 1npt:Q, 1npt:R, 1nq5:O, 1nq5:Q, 1nq5:A, 1nq5:C, 1nqa:O, 1nqa:P, 1nqa:Q, 1nqa:R, 1nqo:O, 1nqo:Q, 1nqo:A, 1nqo:C
25 3dmt:A 359 351 0.5255 0.4875 0.4986 5.35e-117 3dmt:B, 3dmt:C, 3dmt:D, 3ids:D, 1k3t:C, 1ml3:B, 1ml3:C, 1ml3:D, 1qxs:C, 1qxs:D, 1qxs:A, 1qxs:B, 2x0n:A, 2x0n:B, 2x0n:O, 2x0n:P, 2x0n:Q, 2x0n:R
26 2ep7:B 339 339 0.5225 0.5133 0.5133 6.64e-112 2ep7:A
27 1a7k:A 358 349 0.5255 0.4888 0.5014 1.20e-111 1a7k:B, 1a7k:C, 1a7k:D, 1gyp:A, 1gyp:B, 1gyp:C, 1gyp:D, 1gyq:A, 1gyq:B, 1gyq:C, 1gyq:D, 1i32:A, 1i32:B, 1i32:C, 1i32:D, 1i32:E, 1i32:F, 1i33:A, 1i33:B, 1i33:C, 1i33:D, 1i33:E, 1i33:F
28 8br4:A 339 334 0.5315 0.5221 0.5299 1.54e-111 8br4:B, 8br4:C, 8br4:D, 8br4:E, 8br4:F, 8br4:G, 8br4:H, 8br4:I, 8br4:J, 8br4:K, 8br4:L, 8br4:M, 8br4:N, 8br4:O, 8br4:P
29 1hdg:O 332 327 0.4925 0.4940 0.5015 8.11e-108 1hdg:Q
30 6ghr:B 342 334 0.4985 0.4854 0.4970 1.75e-106 4boy:A, 4boy:B, 6gfo:A, 6gfo:B, 6gfo:C, 6gfo:D, 6gfp:A, 6gfp:B, 6gfq:B, 6gfq:A, 6gfr:A, 6gfr:B, 6gg7:B, 6gg7:A, 6ghl:A, 6ghl:D, 6ghl:B, 6ghl:C, 6ghr:D, 6ghr:A, 6ghr:C, 6gve:D, 6gve:A, 6gve:E, 6gve:F, 6gve:I, 6gve:K, 6gve:N, 6gve:O, 3zcx:A, 3zcx:B, 3zdf:B, 3zdf:A
31 3hja:A 334 337 0.5195 0.5180 0.5134 2.99e-106 3hja:B, 3hja:C, 3hja:D
32 1cer:O 331 327 0.5165 0.5196 0.5260 1.31e-105 1cer:P, 1cer:Q, 1cer:R, 1cer:A, 1cer:B, 1cer:C, 1cer:D, 2g82:O, 2g82:P, 2g82:Q, 2g82:R, 2g82:A, 2g82:B, 2g82:C, 2g82:D, 1vc2:A
33 3doc:A 335 330 0.4775 0.4746 0.4818 1.84e-103 3doc:B, 3doc:C, 3doc:D
34 3gnq:C 335 332 0.4925 0.4896 0.4940 1.79e-102 3gnq:B, 3gnq:D, 3gnq:E, 3gnq:F, 3gnq:G, 3gnq:H
35 8hrq:B 336 329 0.4925 0.4881 0.4985 1.38e-101 8hro:A, 8hro:B, 8hrp:A, 8hrp:B, 8hrp:C, 8hrp:D, 8hrp:E, 8hrp:F, 8hrp:G, 8hrp:H, 8hrq:A, 8hrr:A, 8hrr:B, 8hrs:A, 8hrs:B, 8hrs:C, 8hrs:D, 8hrt:A, 8hrt:B, 8hrt:C, 8hrt:D
36 1obf:O 335 332 0.4865 0.4836 0.4880 1.34e-100 1obf:P
37 7bew:A 330 330 0.4685 0.4727 0.4727 5.72e-100 7bex:A
38 5m6d:A 346 327 0.4685 0.4509 0.4771 1.11e-97 6fzh:A, 6fzh:B, 6ite:P, 6ite:Q, 6ite:R, 6ite:O
39 3l0d:A 332 333 0.4595 0.4608 0.4595 1.12e-97 3l0d:B
40 5utm:A 345 328 0.4565 0.4406 0.4634 3.55e-95 5jy6:A, 5jy6:B, 5jy6:C, 5jy6:D, 5jya:A, 5jya:B, 5jya:C, 5jya:D, 5jye:A, 5jye:C, 4qx6:A, 4qx6:B, 4qx6:C, 4qx6:D, 5utl:A, 5utl:B, 5utl:C, 5utl:D, 5utm:B, 5utm:C, 5utm:D, 5v8x:A, 5v8x:B, 5v8x:C, 5v8x:D, 5y37:A, 5y37:B
41 7jwk:C 333 328 0.4655 0.4655 0.4726 6.74e-95 7jwk:A, 7jwk:B, 7jwk:D
42 6fzi:B 332 327 0.4595 0.4608 0.4679 1.59e-94 6fzi:A, 6fzi:C, 6fzi:D
43 3lvf:P 338 328 0.4505 0.4438 0.4573 2.64e-94 3hq4:R, 3hq4:O, 3hq4:P, 3hq4:Q, 3k73:Q, 3k73:O, 3k73:P, 3k73:R, 3k9q:Q, 3k9q:O, 3k9q:P, 3k9q:R, 3ksd:Q, 3ksd:R, 3ksd:O, 3ksd:P, 3ksz:O, 3ksz:P, 3ksz:R, 3ksz:Q, 3kv3:O, 3kv3:Q, 3kv3:R, 3kv3:P, 3l4s:Q, 3l4s:P, 3l4s:O, 3l4s:R, 3l6o:Q, 3l6o:P, 3l6o:R, 3l6o:O, 3lc1:P, 3lc1:R, 3lc1:O, 3lc1:Q, 3lc2:O, 3lc2:Q, 3lc2:R, 3lc2:P, 3lvf:R, 3lvf:O, 3lvf:Q, 5t73:A, 5t73:B, 5t73:C, 5t73:D, 3vaz:P, 3vaz:R, 3vaz:O, 3vaz:Q, 3vaz:B, 3vaz:A
44 1nbo:O 337 330 0.4655 0.4599 0.4697 7.74e-94 1jn0:O, 1jn0:A, 1jn0:B, 1nbo:A, 1nbo:B, 2pkq:P, 2pkq:R, 2pkq:S, 2pkr:O, 2pkr:R, 2pkr:P, 2pkr:Q, 2pkr:A, 2pkr:B, 2pkr:C, 2pkr:D, 2pkr:H, 2pkr:I, 2pkr:L, 2pkr:M, 7q53:P, 7q53:R, 7q54:R, 7q54:P, 7q54:B, 7q54:D, 7q55:P, 7q55:R, 7q55:B, 7q55:D, 7q55:F, 7q55:H, 7q55:J, 7q55:L, 7q56:J, 7q56:L, 7q56:B, 7q56:D, 7q56:R, 7q56:P, 7q56:H, 7q56:F, 7q57:P, 7q57:R, 7q57:B, 7q57:D, 7q57:H, 7q57:F, 7q57:J, 7q57:L, 7q57:N, 7q57:T, 1rm3:O, 1rm3:A, 1rm3:B, 1rm4:O, 1rm4:A, 1rm4:B, 1rm5:O, 1rm5:A, 1rm5:B
45 3b1j:A 338 331 0.4595 0.4527 0.4622 2.32e-93 3b1j:B, 3b1k:A, 3b1k:H, 3b1k:B, 3b1k:G, 3b20:A, 3b20:B, 3b20:O, 3b20:P, 3b20:Q, 3b20:R, 2d2i:A, 2d2i:B, 2d2i:O, 2d2i:P, 2d2i:Q, 2d2i:R, 2duu:A, 2duu:B, 2duu:O, 2duu:P, 2duu:Q, 2duu:R
46 5vmt:B 334 323 0.4324 0.4311 0.4458 5.25e-92 5vmt:A, 5vmt:C, 5vmt:D, 5vmt:F, 5vmt:G, 5vmt:H
47 7zq3:R 348 331 0.4535 0.4339 0.4562 6.64e-88 7zq3:O, 7zq4:O, 7zq4:R, 7zqk:O, 7zqk:R
48 7q54:C 368 333 0.4625 0.4185 0.4625 3.55e-87 2pkq:O, 2pkq:Q, 2pkq:T, 7q53:O, 7q53:Q, 7q54:Q, 7q54:O, 7q54:A, 7q55:O, 7q55:Q, 7q55:A, 7q55:C, 7q55:E, 7q55:G, 7q55:I, 7q55:K, 7q56:K, 7q56:E, 7q56:I, 7q56:A, 7q56:G, 7q56:C, 7q56:Q, 7q56:O, 7q57:O, 7q57:Q, 7q57:A, 7q57:C, 7q57:G, 7q57:E, 7q57:I, 7q57:K, 7q57:M, 7q57:S
49 3k2b:A 337 330 0.4535 0.4481 0.4576 3.79e-87 3k2b:B, 3k2b:C, 3k2b:D, 3k2b:E, 3k2b:F, 3k2b:G, 3k2b:H, 3k2b:O, 3k2b:Q, 6kez:A, 6kez:B, 6kez:C, 6kez:D, 6kez:E, 6kez:F, 6kez:G, 6kez:H, 3qv1:A, 3qv1:D, 3qv1:B, 3qv1:C, 3qv1:F, 3qv1:E, 3rvd:A, 3rvd:D, 3rvd:B, 3rvd:C, 3rvd:O, 3rvd:Q, 3rvd:F, 3rvd:G, 3rvd:E, 3rvd:H
50 7c5o:O 338 329 0.4535 0.4467 0.4590 6.44e-87 7c5f:O, 7c5f:P, 7c5f:Q, 7c5f:R, 7c5g:O, 7c5g:P, 7c5g:Q, 7c5g:R, 7c5h:O, 7c5h:P, 7c5h:Q, 7c5h:R, 7c5i:O, 7c5i:P, 7c5i:Q, 7c5i:R, 7c5j:O, 7c5j:P, 7c5j:Q, 7c5j:R, 7c5k:O, 7c5k:P, 7c5k:Q, 7c5k:R, 7c5l:O, 7c5l:P, 7c5l:Q, 7c5l:R, 7c5m:O, 7c5m:P, 7c5m:Q, 7c5m:R, 7c5n:O, 7c5n:P, 7c5n:Q, 7c5n:R, 7c5o:P, 7c5o:Q, 7c5o:R, 7c5p:O, 7c5p:P, 7c5p:Q, 7c5p:R, 7c5q:O, 7c5q:P, 7c5q:Q, 7c5q:R, 7c5r:O, 7c5r:P, 7c5r:Q, 7c5r:R, 7c7k:O, 7c7k:P, 7c7k:Q, 7c7k:R
51 8hmn:D 340 328 0.4595 0.4500 0.4665 2.12e-84 8hmn:A, 8hmn:B, 8hmn:C, 6iqm:A, 6iqm:B, 6iqm:C, 6iqm:D
52 5ld5:C 342 332 0.4234 0.4123 0.4247 2.86e-84 5ld5:A, 5ld5:B, 5ld5:D
53 7www:A 336 328 0.4505 0.4464 0.4573 2.23e-82
54 2xf8:M 327 336 0.3964 0.4037 0.3929 9.68e-79 2xf8:A, 2xf8:C, 2xf8:E, 2xf8:G, 2xf8:I, 2xf8:K, 2xf8:O
55 9iil:A 341 339 0.4024 0.3930 0.3953 4.65e-75 9iil:B, 9iil:C, 9iil:D, 9iim:A, 9iim:C, 9iim:B, 9iim:D, 9ij6:A, 9ij6:C, 9ij6:B, 9ij6:D, 8zn1:A, 8zn1:C, 8zn1:B, 8zn1:D, 8zn4:A, 8zn4:B, 8zn4:C, 8zn4:D, 8zoz:A, 8zoz:C, 8zoz:B, 8zoz:D
56 5vmt:E 293 320 0.3844 0.4369 0.4000 4.47e-69
57 8jb1:A 468 345 0.3904 0.2778 0.3768 6.75e-56 8jb1:B
58 3tz6:A 342 100 0.0751 0.0731 0.2500 0.74 3vos:A
59 6k0k:C 397 115 0.0841 0.0705 0.2435 0.85
60 6c8w:A 357 108 0.0931 0.0868 0.2870 1.7 6c85:A, 6c85:B, 6c8w:B
61 1ys4:A 348 104 0.0751 0.0718 0.2404 1.8 1ys4:B
62 8fkv:NI 647 44 0.0450 0.0232 0.3409 2.4 8fkt:NI, 8fku:NI, 8fkw:NI, 8fkx:NI, 8fky:NI
63 6k0k:A 479 117 0.0841 0.0585 0.2393 3.0
64 2czc:A 334 29 0.0360 0.0359 0.4138 3.1 2czc:B, 2czc:C, 2czc:D
65 7fh4:A 140 44 0.0390 0.0929 0.2955 4.7 7fh4:B, 7fh9:A
66 4xr9:A 456 112 0.0931 0.0680 0.2768 6.7
67 2dki:A 615 58 0.0631 0.0341 0.3621 9.2 2dkh:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218