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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TKGTTSMGQRHGRTHILCRRCGRNSYHVQWERCAACAYPRASRRRYNWSVKAIKRRRTGTGRCRYLKVVNRRIANHFKTP

The query sequence (length=80) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4v8m:Bn 83 80 0.9375 0.9036 0.9375 5.99e-42 8a3w:j, 8a98:j, 6az3:j, 3jcs:j, 8ova:Bn, 8ove:Bn, 8ovj:j, 8rxh:Lj, 8rxx:Lj, 5t2a:l, 5t5h:n
2 3j79:c 89 76 0.5625 0.5056 0.5921 1.28e-30 3jbn:Ac, 3jbo:Ac, 3jbp:Ac, 8tpu:Ac, 5umd:c
3 4v6w:Cj 92 78 0.6125 0.5326 0.6282 2.96e-30 6xu8:Cj
4 7old:Lj 88 79 0.6000 0.5455 0.6076 7.57e-28 8i9p:Lj, 8i9r:Lj, 8i9t:Lj, 8i9v:Lj, 8i9w:Lj, 8i9x:Lj, 8i9y:Lj, 8i9z:Lj, 8ia0:Lj, 7olc:Lj, 8oo0:Lj, 8pv1:Lj, 8pv2:Lj, 8pv3:Lj, 8pv4:Lj, 8pv5:Lj, 8pv6:Lj, 8pv7:Lj, 8pv8:Lj, 8pvk:Lj, 8pvl:Lj, 7r81:l1, 7z3n:Lj, 7z3o:Lj
5 5it7:jj 85 78 0.5500 0.5176 0.5641 8.39e-28 6uz7:Bj
6 7qiw:l 87 77 0.5875 0.5402 0.6104 9.90e-28 8azw:V, 8b2l:V3, 7qiz:l
7 4v6i:Bl 88 78 0.5625 0.5114 0.5769 3.04e-27 8aaf:W, 8agt:W, 8agu:W, 8agv:W, 8agw:W, 8agx:W, 8agz:W, 5apn:j, 5apo:j, 7azy:g, 7b7d:Lf, 8bip:Lj, 8bjq:Lj, 8bn3:O7, 8bqd:AF, 8bqx:AF, 7bt6:j, 7btb:j, 6c0f:j, 6cb1:j, 8ccs:V, 8cdl:V, 8cdr:V, 8ceh:V, 8cf5:V, 8cg8:V, 8cgn:V, 8civ:V, 8cku:V, 8cmj:V, 5dat:O7, 5dat:o7, 5dc3:O7, 5dc3:o7, 5dge:O7, 5dge:o7, 5dgf:O7, 5dgf:o7, 5dgv:O7, 5dgv:o7, 6elz:j, 6em1:j, 6em3:j, 6em4:j, 6em5:j, 8eub:Aj, 8evp:Aj, 8evq:Aj, 8evr:Aj, 8evs:Aj, 8evt:Aj, 8ewb:Aj, 8ewc:Aj, 5fci:O7, 5fci:o7, 5fcj:O7, 5fcj:o7, 6ft6:j, 5gak:l, 6gq1:j, 6gqb:j, 6gqv:j, 5h4p:j, 6hd7:l, 8hfr:jh, 6hhq:AK, 6hhq:DL, 5i4l:O7, 5i4l:o7, 6i7o:AF, 6i7o:XF, 3j6x:77, 3j6y:77, 3j77:87, 3j78:87, 3jct:j, 5jcs:j, 5juo:OA, 5jup:OA, 5jus:OA, 5jut:OA, 5juu:OA, 8k2d:Lj, 8k82:Lj, 5lyb:O7, 5lyb:o7, 5m1j:j5, 6m62:j, 5mc6:AF, 5mei:AK, 5mei:DL, 7mpi:Aj, 7mpj:Aj, 6n8j:j, 6n8k:j, 6n8l:j, 6n8m:w, 6n8n:w, 6n8o:w, 7n8b:Aj, 7nac:j, 5ndg:O7, 5ndg:o7, 5ndv:O7, 5ndv:o7, 5ndw:O7, 5ndw:o7, 7nrc:Ll, 7nrd:Ll, 5obm:O7, 5obm:o7, 7of1:j, 7oh3:j, 7ohp:j, 7ohq:j, 7ohr:j, 7ohs:j, 7ohu:j, 7ohv:j, 7ohw:j, 7ohx:j, 7ohy:j, 6oig:j, 5on6:AK, 5on6:DL, 7osa:eL37, 7osm:eL37, 8p8m:RJ, 8p8n:RJ, 8p8u:RJ, 8pfr:RJ, 6q8y:AF, 6qik:i, 6qt0:i, 6qtz:i, 7r7a:j, 6r84:l, 6r86:l, 6r87:l, 6ri5:i, 7rr5:Lj, 6rzz:i, 6s05:i, 6s47:Al, 6snt:ag, 6sv4:AF, 6sv4:XF, 6sv4:zF, 6t4q:Lj, 5t62:w, 5t6r:w, 6t7i:Lj, 6t7t:Lj, 6t83:jb, 6t83:U, 5tbw:AK, 5tbw:DL, 6tb3:AF, 5tga:O7, 5tga:o7, 5tgm:O7, 5tgm:o7, 6tnu:AF, 7too:AL37, 7top:AL37, 7u0h:j, 4u3m:O7, 4u3m:o7, 4u3n:O7, 4u3n:o7, 4u3u:O7, 4u3u:o7, 4u4n:O7, 4u4n:o7, 4u4o:O7, 4u4o:o7, 4u4q:O7, 4u4q:o7, 4u4r:O7, 4u4r:o7, 4u4u:O7, 4u4u:o7, 4u4y:O7, 4u4y:o7, 4u4z:O7, 4u4z:o7, 4u50:O7, 4u50:o7, 4u51:O7, 4u51:o7, 4u52:O7, 4u52:o7, 4u53:O7, 4u53:o7, 4u55:O7, 4u55:o7, 4u56:O7, 4u56:o7, 4u6f:O7, 4u6f:o7, 7ug6:j, 7uoo:j, 7uqb:j, 7uqz:j, 7v08:j, 4v4b:BY, 4v7h:BY, 4v7r:Bd, 4v7r:Dd, 4v88:Bj, 4v88:Dj, 4v8t:j, 4v8y:Bj, 4v8z:Bj, 8v83:j, 8v84:j, 8v87:j, 4v91:j, 6woo:j, 6xiq:j, 6xir:j, 8y0u:Lj, 6ylg:j, 6ylh:j, 6ylx:j, 6yly:j, 5z3g:n, 7z34:j, 6z6j:Lj, 6z6k:Lj, 7zpq:Bi, 7zrs:Bi, 7zs5:Bk, 7zuw:Bi, 7zux:Ei, 7zw0:Lm
8 8c3a:AK 86 78 0.5500 0.5116 0.5641 6.27e-27 8c3a:CE, 8cq7:AK, 8cq7:CE, 8cqw:AK, 8cqw:CE, 8cre:AK, 8cre:CE, 8oeq:AK, 8oeq:CE, 7pzy:AK, 7q08:AK, 7q0f:AK, 7q0p:AK, 7q0r:AK, 8q5i:AK
9 8eug:j 83 79 0.5375 0.5181 0.5443 5.17e-26 8esq:j, 8esr:j, 8etc:j, 8etg:j, 8eth:j, 8eti:j, 8etj:j, 8eui:j, 8eup:j, 8euy:j, 8ev3:j
10 4v3p:Ll 94 77 0.5375 0.4574 0.5584 1.13e-25 8ip8:UA, 8ipa:UA, 8ipb:UA, 8jiv:Cj, 4v7e:Cj
11 6xu6:Cj 87 75 0.5375 0.4943 0.5733 1.30e-25 6xu7:Cj
12 4v6x:Cj 90 78 0.5250 0.4667 0.5385 1.14e-24 7a01:C2, 8a3d:d, 5aj0:Aj, 8b5l:j, 8b6c:j, 9bdl:AL37, 9bdn:AL37, 9bdp:AL37, 7bhp:Lj, 8bhf:W1, 8bpo:i2, 8btk:Bj, 7cpu:Lj, 7cpv:Lj, 4d5y:j, 4d67:j, 6d90:j, 6d9j:j, 9f1b:Bj, 9f1c:Bj, 9f1d:Bj, 7f5s:Lj, 8fkp:LW, 8fkq:LW, 8fkr:LW, 8fks:LW, 8fkt:LW, 8fku:LW, 8fkv:LW, 8fkw:LW, 8fkx:LW, 8fky:LW, 8fkz:LW, 8fl2:LW, 8fl3:LW, 8fl4:LW, 8fl6:LW, 8fl7:LW, 8fl9:LW, 8fla:LW, 8flb:LW, 8flc:LW, 8fld:LW, 8fle:LW, 8flf:LW, 6frk:j, 6ftg:j, 6fti:j, 6ftj:j, 8g5y:Lj, 8g5z:Lj, 8g60:Lj, 8g61:Lj, 8g6j:Lj, 8glp:Lj, 6gz3:Aj, 6gz4:Aj, 6gz5:Aj, 6hcf:j3, 6hcj:j3, 6hcm:j3, 6hcq:j3, 8idt:M, 8idy:M, 8ie3:M, 8ifd:2d, 8ife:2d, 8ine:M, 8inf:M, 8ink:M, 6ip5:2d, 6ip6:2d, 6ip8:2d, 8ipd:M, 8ipx:M, 8ipy:M, 8ir1:M, 8ir3:M, 3j7o:j, 3j7p:j, 3j7q:j, 3j7r:j, 3j92:j, 3jag:j, 3jah:j, 3jai:j, 3jaj:j, 3jan:j, 8jdj:o, 8jdk:o, 8jdl:o, 8jdm:o, 8k2c:Lj, 5lks:Lj, 6lqm:M, 6lsr:M, 6lss:M, 7ls1:d2, 7ls2:d2, 6lu8:M, 5lzs:j, 5lzt:j, 5lzu:j, 5lzv:j, 5lzw:j, 5lzx:j, 5lzy:j, 5lzz:j, 7mdz:j, 6mtb:j, 6mtc:j, 6mtd:j, 6mte:j, 7nfx:j, 7nwg:j3, 7nwh:j, 7nwi:j, 7o7y:Bj, 7o7z:Bj, 7o80:Bj, 7o81:Bj, 7obr:j, 8ohd:Lj, 8oj0:Lj, 8oj5:Lj, 8oj8:Lj, 6ole:k, 6olf:k, 6olg:Aj, 6oli:k, 6olz:Aj, 6om0:k, 6om7:k, 7ow7:d, 7oya:j1, 7oyb:j1, 7oyc:j1, 7oyd:j, 8p2k:Bj, 6p5i:Aj, 6p5j:Aj, 6p5k:Aj, 6p5n:Aj, 8q7z:Bj, 8q87:Bj, 8qfd:j, 7qgg:k, 8qoi:Lj, 7qvp:Mj, 7qvp:Lj, 7qwq:j, 7qwr:j, 7qws:j, 6qzp:Lj, 6r5q:j, 6r6g:j, 6r6p:j, 6r7q:j, 8rjb:j, 8rjc:j, 8rjd:j, 8scb:j, 6sgc:j2, 6swa:h, 5t2c:d, 6t59:j3, 7tm3:j, 7toq:AL37, 7tor:AL37, 7tut:j, 7ucj:j, 7uck:j, 4ug0:Lj, 4ujc:Bj, 4ujd:Aj, 4uje:Cj, 4v5z:B2, 6w6l:k, 6xa1:Lj, 7xnx:Lj, 7xny:Lj, 8xsx:Lj, 8xsy:Lj, 8xsz:Lj, 6y0g:Lj, 8y0w:Lj, 8y0x:Lj, 6y2l:Lj, 6y57:Lj, 6y6x:Lj, 8yoo:Lj, 8yop:Lj, 6z6l:Lj, 6z6m:Lj, 6z6n:Lj, 7zjw:Lm, 7zjx:Lm, 6zm7:Lj, 6zme:Lj, 6zmi:Lj, 6zmo:Lj, 6zvk:C2
13 6zj3:Ly 106 74 0.5250 0.3962 0.5676 8.09e-24
14 4v8p:AA 91 80 0.5250 0.4615 0.5250 8.79e-24 4v8p:DA, 4v8p:FA, 4v8p:HA
15 5xxb:i 87 77 0.5500 0.5057 0.5714 1.03e-22
16 8brm:Lk 88 71 0.4625 0.4205 0.5211 1.06e-21 8br8:Lk, 8bsi:Lk, 8bsj:Lk, 8btd:Lk, 8btr:Lk, 8fru:j, 7pwg:j, 7pwo:j2
17 9bh5:Cj 88 78 0.5250 0.4773 0.5385 3.06e-21 9cai:Cj
18 5xy3:j 77 71 0.4250 0.4416 0.4789 1.61e-19
19 6rm3:LJJ 90 69 0.4375 0.3889 0.5072 3.42e-17
20 8bf9:j 73 78 0.4625 0.5068 0.4744 6.39e-15
21 6zu5:LJJ 89 78 0.5000 0.4494 0.5128 7.15e-12
22 8p5d:LJJ 89 67 0.3375 0.3034 0.4030 8.14e-12 8p60:LJJ, 8p60:KJJ, 7qca:LJJ
23 7qep:O7 86 67 0.4125 0.3837 0.4925 2.31e-10
24 3cc2:1 56 51 0.2750 0.3929 0.4314 8.41e-10 3cc4:1, 3cc7:1, 3cce:1, 3ccj:1, 3ccl:1, 3ccm:1, 3ccq:1, 3ccr:1, 3ccs:1, 3ccu:1, 3ccv:1, 3cd6:1, 3cma:1, 3cme:1, 3cpw:Z, 3cxc:Z, 1ffk:X, 3g4s:1, 3g6e:1, 3g71:1, 3i55:1, 3i56:1, 1jj2:Z, 1k73:2, 1k8a:2, 1k9m:2, 1kc8:2, 1kd1:2, 1kqs:Z, 1m1k:2, 1m90:2, 1n8r:2, 1nji:2, 2otj:1, 2otl:1, 3ow2:Z, 1q7y:2, 1q81:2, 1q82:2, 1q86:2, 2qa4:1, 2qex:1, 1qvf:Z, 1qvg:Z, 1s72:1, 4v9f:1, 1vq4:1, 1vq5:1, 1vq6:1, 1vq7:1, 1vq8:1, 1vq9:1, 1vqk:1, 1vql:1, 1vqm:1, 1vqn:1, 1vqo:1, 1vqp:1, 1w2b:Z, 1yhq:1, 1yi2:1, 1yij:1, 1yit:1, 1yj9:1, 1yjn:1, 1yjw:1
25 8hku:L37E 54 52 0.3125 0.4630 0.4808 2.45e-08 8hkv:L37E, 8hky:L37E, 8hkz:L37E, 8hl1:L37E, 8hl2:L37E, 8hl3:L37E, 8hl4:L37E, 8hl5:L37E
26 4v4n:Ae 62 49 0.3250 0.4194 0.5306 4.82e-08 4v6u:Be
27 6skf:Bh 62 56 0.3375 0.4355 0.4821 2.18e-07 6skg:Bh, 6th6:Bh
28 8q7h:A 1403 34 0.1500 0.0086 0.3529 1.0
29 6rxs:A 218 53 0.1750 0.0642 0.2642 3.3
30 4pj3:A 1335 21 0.1375 0.0082 0.5238 4.0 7a5p:U, 6icz:Q, 6id1:Q, 7w59:Q, 7w5a:Q, 7w5b:Q, 5xjc:Q
31 1yol:A 256 49 0.1625 0.0508 0.2653 5.9 7ah3:B, 6ate:A, 5d10:A, 5d10:B, 5d11:A, 5d11:B, 5d12:B, 7d57:B, 7d5o:B, 3el7:A, 3en5:A, 3en6:B, 3en7:A, 4fic:A, 4fic:B, 8haq:A, 8haq:B, 6hve:B, 6hvf:A, 6hvf:B, 2hwo:A, 2hwo:B, 2hwp:A, 2hwp:B, 8jf3:A, 8jf3:B, 4lgg:A, 4lgg:B, 4lgh:A, 4lgh:B, 3lok:A, 3lok:B, 2qlq:A, 2qlq:B, 3qlf:A, 2qq7:A, 2qq7:B, 3uqf:B, 6wiw:A, 4ybj:B, 1yol:B
32 1y57:A 452 51 0.1625 0.0288 0.2549 7.2 1a07:A, 1a07:B, 1a08:A, 1a08:B, 1a09:A, 1a09:B, 1a1a:A, 1a1a:B, 1a1b:A, 1a1b:B, 1a1c:A, 1a1c:B, 1a1e:A, 1a1e:B, 4agw:A, 4agw:B, 7ah3:A, 2bdf:A, 2bdf:B, 2bdj:A, 1bkm:A, 5bmm:A, 5bmm:B, 5d12:A, 7d57:A, 7d5o:A, 3d7t:B, 4dgg:A, 4dgg:B, 3dqw:A, 3dqw:B, 3dqw:C, 3dqw:D, 3dqx:A, 3dqx:B, 6e6e:A, 6e6e:B, 6e6e:C, 6e6e:D, 6e6e:E, 6e6e:F, 6e6e:G, 6e6e:H, 3el8:A, 3en4:A, 3en4:B, 3en5:B, 1f1w:A, 3f3t:A, 3f3u:A, 3f3u:B, 3f3v:A, 3f3v:B, 3f3w:A, 3f3w:B, 6f3f:A, 4f5a:A, 4f5b:A, 3f6x:A, 3f6x:B, 3f6x:C, 3f6x:D, 3g5d:A, 3g5d:B, 3g6g:A, 3g6g:B, 3g6h:B, 3geq:A, 3geq:B, 2h8h:A, 1hcs:B, 1hct:B, 4hvu:A, 4hvv:A, 6hve:A, 4hxj:A, 1is0:A, 1is0:B, 5j5s:A, 5j5s:B, 8jn8:A, 8jn9:A, 4k11:A, 8k79:A, 8k79:B, 5k9i:A, 5k9i:B, 1kc2:A, 1ksw:A, 6l8l:A, 6l8l:B, 6l8l:C, 6l8l:D, 4mcv:A, 4mcv:B, 4mxo:A, 4mxo:B, 4mxx:A, 4mxx:B, 4mxy:A, 4mxy:B, 4mxz:A, 4mxz:B, 7nes:A, 7ng7:A, 1nlo:C, 1nlp:C, 1nzl:B, 1nzv:B, 4o2p:A, 4o2p:B, 1o41:A, 1o42:A, 1o43:A, 1o44:A, 1o45:A, 1o46:A, 1o47:A, 1o48:A, 1o49:A, 1o4a:A, 1o4b:A, 1o4c:A, 1o4d:A, 1o4e:A, 1o4f:A, 1o4g:A, 1o4h:A, 1o4i:A, 1o4j:A, 1o4k:A, 1o4n:A, 1o4o:A, 1o4p:A, 1o4q:A, 1o4r:A, 5oav:A, 5oav:C, 5ob0:A, 5ob1:A, 5ob2:A, 5ob2:C, 3oez:A, 3oez:B, 2oiq:A, 7ote:A, 7ote:B, 1p13:B, 1p13:A, 1prl:C, 1prm:C, 3qlf:B, 3qlg:A, 3qlg:B, 4qt7:A, 1qwe:A, 1qwf:A, 1rlp:C, 1rlq:C, 4rtv:A, 4rtw:A, 4rtw:C, 4rty:A, 4rtz:A, 1sha:A, 1shb:A, 1shd:A, 1skj:A, 1sps:A, 1sps:B, 1sps:C, 2src:A, 3svv:A, 3svv:B, 5swh:A, 5swh:B, 5sys:A, 5sys:B, 5t0p:A, 5t0p:B, 5teh:A, 5teh:B, 3tz7:A, 3tz7:B, 3tz8:A, 3tz8:B, 3tz9:A, 3tz9:B, 3u4w:A, 3u51:A, 3u51:B, 4u5j:A, 4u5j:B, 3uqf:A, 3uqg:A, 3uqg:B, 7wf5:A, 7wf5:B, 6wiw:B, 8xn8:A, 5xp5:A, 5xp5:B, 5xp7:A, 5xp7:B, 4ybj:A, 4ybk:A, 1yom:A, 1yom:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218