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●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
TKGTTSFGKRHNKTHTICRRCGNSSYHLQKSKCSQCGYPAAKTRSFNWSRKAKGRKAQGTGRMRYLKNLRRRFRNGLREG
GAAKKKT

The query sequence (length=87) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 6xu6:Cj 87 87 1.0000 1.0000 1.0000 1.59e-58 6xu7:Cj
2 4v6w:Cj 92 86 0.7586 0.7174 0.7674 1.51e-43 6xu8:Cj
3 5it7:jj 85 81 0.6437 0.6588 0.6914 9.52e-37 6uz7:Bj
4 4v6i:Bl 88 83 0.6437 0.6364 0.6747 2.29e-36 8aaf:W, 8agt:W, 8agu:W, 8agv:W, 8agw:W, 8agx:W, 8agz:W, 5apn:j, 5apo:j, 7azy:g, 7b7d:Lf, 8bip:Lj, 8bjq:Lj, 8bn3:O7, 8bqd:AF, 8bqx:AF, 7bt6:j, 7btb:j, 6c0f:j, 6cb1:j, 8ccs:V, 8cdl:V, 8cdr:V, 8ceh:V, 8cf5:V, 8cg8:V, 8cgn:V, 8civ:V, 8cku:V, 8cmj:V, 5dat:O7, 5dat:o7, 5dc3:O7, 5dc3:o7, 5dge:O7, 5dge:o7, 5dgf:O7, 5dgf:o7, 5dgv:O7, 5dgv:o7, 6elz:j, 6em1:j, 6em3:j, 6em4:j, 6em5:j, 8eub:Aj, 8evp:Aj, 8evq:Aj, 8evr:Aj, 8evs:Aj, 8evt:Aj, 8ewb:Aj, 8ewc:Aj, 5fci:O7, 5fci:o7, 5fcj:O7, 5fcj:o7, 6ft6:j, 5gak:l, 6gq1:j, 6gqb:j, 6gqv:j, 5h4p:j, 6hd7:l, 8hfr:jh, 6hhq:AK, 6hhq:DL, 5i4l:O7, 5i4l:o7, 6i7o:AF, 6i7o:XF, 3j6x:77, 3j6y:77, 3j77:87, 3j78:87, 3jct:j, 5jcs:j, 5juo:OA, 5jup:OA, 5jus:OA, 5jut:OA, 5juu:OA, 8k2d:Lj, 8k82:Lj, 5lyb:O7, 5lyb:o7, 5m1j:j5, 6m62:j, 5mc6:AF, 5mei:AK, 5mei:DL, 7mpi:Aj, 7mpj:Aj, 6n8j:j, 6n8k:j, 6n8l:j, 6n8m:w, 6n8n:w, 6n8o:w, 7n8b:Aj, 7nac:j, 5ndg:O7, 5ndg:o7, 5ndv:O7, 5ndv:o7, 5ndw:O7, 5ndw:o7, 7nrc:Ll, 7nrd:Ll, 5obm:O7, 5obm:o7, 7of1:j, 7oh3:j, 7ohp:j, 7ohq:j, 7ohr:j, 7ohs:j, 7ohu:j, 7ohv:j, 7ohw:j, 7ohx:j, 7ohy:j, 6oig:j, 5on6:AK, 5on6:DL, 7osa:eL37, 7osm:eL37, 8p8m:RJ, 8p8n:RJ, 8p8u:RJ, 8pfr:RJ, 6q8y:AF, 6qik:i, 6qt0:i, 6qtz:i, 7r7a:j, 6r84:l, 6r86:l, 6r87:l, 6ri5:i, 7rr5:Lj, 6rzz:i, 6s05:i, 6s47:Al, 6snt:ag, 6sv4:AF, 6sv4:XF, 6sv4:zF, 6t4q:Lj, 5t62:w, 5t6r:w, 6t7i:Lj, 6t7t:Lj, 6t83:jb, 6t83:U, 5tbw:AK, 5tbw:DL, 6tb3:AF, 5tga:O7, 5tga:o7, 5tgm:O7, 5tgm:o7, 6tnu:AF, 7too:AL37, 7top:AL37, 7u0h:j, 4u3m:O7, 4u3m:o7, 4u3n:O7, 4u3n:o7, 4u3u:O7, 4u3u:o7, 4u4n:O7, 4u4n:o7, 4u4o:O7, 4u4o:o7, 4u4q:O7, 4u4q:o7, 4u4r:O7, 4u4r:o7, 4u4u:O7, 4u4u:o7, 4u4y:O7, 4u4y:o7, 4u4z:O7, 4u4z:o7, 4u50:O7, 4u50:o7, 4u51:O7, 4u51:o7, 4u52:O7, 4u52:o7, 4u53:O7, 4u53:o7, 4u55:O7, 4u55:o7, 4u56:O7, 4u56:o7, 4u6f:O7, 4u6f:o7, 7ug6:j, 7uoo:j, 7uqb:j, 7uqz:j, 7v08:j, 4v4b:BY, 4v7h:BY, 4v7r:Bd, 4v7r:Dd, 4v88:Bj, 4v88:Dj, 4v8t:j, 4v8y:Bj, 4v8z:Bj, 8v83:j, 8v84:j, 8v87:j, 4v91:j, 6woo:j, 6xiq:j, 6xir:j, 8y0u:Lj, 6ylg:j, 6ylh:j, 6ylx:j, 6yly:j, 5z3g:n, 7z34:j, 6z6j:Lj, 6z6k:Lj, 7zpq:Bi, 7zrs:Bi, 7zs5:Bk, 7zuw:Bi, 7zux:Ei, 7zw0:Lm
5 8eug:j 83 83 0.6437 0.6747 0.6747 1.13e-35 8esq:j, 8esr:j, 8etc:j, 8etg:j, 8eth:j, 8eti:j, 8etj:j, 8eui:j, 8eup:j, 8euy:j, 8ev3:j
6 4v6x:Cj 90 86 0.6552 0.6333 0.6628 1.37e-35 7a01:C2, 8a3d:d, 5aj0:Aj, 8b5l:j, 8b6c:j, 9bdl:AL37, 9bdn:AL37, 9bdp:AL37, 7bhp:Lj, 8bhf:W1, 8bpo:i2, 8btk:Bj, 7cpu:Lj, 7cpv:Lj, 4d5y:j, 4d67:j, 6d90:j, 6d9j:j, 9f1b:Bj, 9f1c:Bj, 9f1d:Bj, 7f5s:Lj, 8fkp:LW, 8fkq:LW, 8fkr:LW, 8fks:LW, 8fkt:LW, 8fku:LW, 8fkv:LW, 8fkw:LW, 8fkx:LW, 8fky:LW, 8fkz:LW, 8fl2:LW, 8fl3:LW, 8fl4:LW, 8fl6:LW, 8fl7:LW, 8fl9:LW, 8fla:LW, 8flb:LW, 8flc:LW, 8fld:LW, 8fle:LW, 8flf:LW, 6frk:j, 6ftg:j, 6fti:j, 6ftj:j, 8g5y:Lj, 8g5z:Lj, 8g60:Lj, 8g61:Lj, 8g6j:Lj, 8glp:Lj, 6gz3:Aj, 6gz4:Aj, 6gz5:Aj, 6hcf:j3, 6hcj:j3, 6hcm:j3, 6hcq:j3, 8idt:M, 8idy:M, 8ie3:M, 8ifd:2d, 8ife:2d, 8ine:M, 8inf:M, 8ink:M, 6ip5:2d, 6ip6:2d, 6ip8:2d, 8ipd:M, 8ipx:M, 8ipy:M, 8ir1:M, 8ir3:M, 3j7o:j, 3j7p:j, 3j7q:j, 3j7r:j, 3j92:j, 3jag:j, 3jah:j, 3jai:j, 3jaj:j, 3jan:j, 8jdj:o, 8jdk:o, 8jdl:o, 8jdm:o, 8k2c:Lj, 5lks:Lj, 6lqm:M, 6lsr:M, 6lss:M, 7ls1:d2, 7ls2:d2, 6lu8:M, 5lzs:j, 5lzt:j, 5lzu:j, 5lzv:j, 5lzw:j, 5lzx:j, 5lzy:j, 5lzz:j, 7mdz:j, 6mtb:j, 6mtc:j, 6mtd:j, 6mte:j, 7nfx:j, 7nwg:j3, 7nwh:j, 7nwi:j, 7o7y:Bj, 7o7z:Bj, 7o80:Bj, 7o81:Bj, 7obr:j, 8ohd:Lj, 8oj0:Lj, 8oj5:Lj, 8oj8:Lj, 6ole:k, 6olf:k, 6olg:Aj, 6oli:k, 6olz:Aj, 6om0:k, 6om7:k, 7ow7:d, 7oya:j1, 7oyb:j1, 7oyc:j1, 7oyd:j, 8p2k:Bj, 6p5i:Aj, 6p5j:Aj, 6p5k:Aj, 6p5n:Aj, 8q7z:Bj, 8q87:Bj, 8qfd:j, 7qgg:k, 8qoi:Lj, 7qvp:Mj, 7qvp:Lj, 7qwq:j, 7qwr:j, 7qws:j, 6qzp:Lj, 6r5q:j, 6r6g:j, 6r6p:j, 6r7q:j, 8rjb:j, 8rjc:j, 8rjd:j, 8scb:j, 6sgc:j2, 6swa:h, 5t2c:d, 6t59:j3, 7tm3:j, 7toq:AL37, 7tor:AL37, 7tut:j, 7ucj:j, 7uck:j, 4ug0:Lj, 4ujc:Bj, 4ujd:Aj, 4uje:Cj, 4v5z:B2, 6w6l:k, 6xa1:Lj, 7xnx:Lj, 7xny:Lj, 8xsx:Lj, 8xsy:Lj, 8xsz:Lj, 6y0g:Lj, 8y0w:Lj, 8y0x:Lj, 6y2l:Lj, 6y57:Lj, 6y6x:Lj, 8yoo:Lj, 8yop:Lj, 6z6l:Lj, 6z6m:Lj, 6z6n:Lj, 7zjw:Lm, 7zjx:Lm, 6zm7:Lj, 6zme:Lj, 6zmi:Lj, 6zmo:Lj, 6zvk:C2
7 7old:Lj 88 80 0.6437 0.6364 0.7000 2.70e-35 8i9p:Lj, 8i9r:Lj, 8i9t:Lj, 8i9v:Lj, 8i9w:Lj, 8i9x:Lj, 8i9y:Lj, 8i9z:Lj, 8ia0:Lj, 7olc:Lj, 8oo0:Lj, 8pv1:Lj, 8pv2:Lj, 8pv3:Lj, 8pv4:Lj, 8pv5:Lj, 8pv6:Lj, 8pv7:Lj, 8pv8:Lj, 8pvk:Lj, 8pvl:Lj, 7r81:l1, 7z3n:Lj, 7z3o:Lj
8 7qiw:l 87 82 0.6322 0.6322 0.6707 1.62e-34 8azw:V, 8b2l:V3, 7qiz:l
9 4v3p:Ll 94 82 0.6092 0.5638 0.6463 2.41e-33 8ip8:UA, 8ipa:UA, 8ipb:UA, 8jiv:Cj, 4v7e:Cj
10 8c3a:AK 86 81 0.5977 0.6047 0.6420 6.47e-33 8c3a:CE, 8cq7:AK, 8cq7:CE, 8cqw:AK, 8cqw:CE, 8cre:AK, 8cre:CE, 8oeq:AK, 8oeq:CE, 7pzy:AK, 7q08:AK, 7q0f:AK, 7q0p:AK, 7q0r:AK, 8q5i:AK
11 4v8p:AA 91 88 0.5747 0.5495 0.5682 7.38e-32 4v8p:DA, 4v8p:FA, 4v8p:HA
12 3j79:c 89 85 0.6092 0.5955 0.6235 4.69e-31 3jbn:Ac, 3jbo:Ac, 3jbp:Ac, 8tpu:Ac, 5umd:c
13 6zj3:Ly 106 69 0.4943 0.4057 0.6232 3.23e-27
14 5xy3:j 77 65 0.4828 0.5455 0.6462 9.79e-27
15 9bh5:Cj 88 86 0.5402 0.5341 0.5465 1.90e-26 9cai:Cj
16 8brm:Lk 88 84 0.4828 0.4773 0.5000 2.78e-25 8br8:Lk, 8bsi:Lk, 8bsj:Lk, 8btd:Lk, 8btr:Lk, 8fru:j, 7pwg:j, 7pwo:j2
17 8bf9:j 73 86 0.5747 0.6849 0.5814 1.80e-23
18 5xxb:i 87 82 0.5402 0.5402 0.5732 6.74e-23
19 4v8m:Bn 83 78 0.4943 0.5181 0.5513 5.70e-22 8a3w:j, 8a98:j, 6az3:j, 3jcs:j, 8ova:Bn, 8ove:Bn, 8ovj:j, 8rxh:Lj, 8rxx:Lj, 5t2a:l, 5t5h:n
20 6rm3:LJJ 90 76 0.4368 0.4222 0.5000 2.60e-18
21 6zu5:LJJ 89 78 0.4828 0.4719 0.5385 2.02e-15
22 8p5d:LJJ 89 76 0.4138 0.4045 0.4737 2.15e-15 8p60:LJJ, 8p60:KJJ, 7qca:LJJ
23 7qep:O7 86 76 0.4598 0.4651 0.5263 2.10e-14
24 3cc2:1 56 51 0.3103 0.4821 0.5294 6.02e-11 3cc4:1, 3cc7:1, 3cce:1, 3ccj:1, 3ccl:1, 3ccm:1, 3ccq:1, 3ccr:1, 3ccs:1, 3ccu:1, 3ccv:1, 3cd6:1, 3cma:1, 3cme:1, 3cpw:Z, 3cxc:Z, 1ffk:X, 3g4s:1, 3g6e:1, 3g71:1, 3i55:1, 3i56:1, 1jj2:Z, 1k73:2, 1k8a:2, 1k9m:2, 1kc8:2, 1kd1:2, 1kqs:Z, 1m1k:2, 1m90:2, 1n8r:2, 1nji:2, 2otj:1, 2otl:1, 3ow2:Z, 1q7y:2, 1q81:2, 1q82:2, 1q86:2, 2qa4:1, 2qex:1, 1qvf:Z, 1qvg:Z, 1s72:1, 4v9f:1, 1vq4:1, 1vq5:1, 1vq6:1, 1vq7:1, 1vq8:1, 1vq9:1, 1vqk:1, 1vql:1, 1vqm:1, 1vqn:1, 1vqo:1, 1vqp:1, 1w2b:Z, 1yhq:1, 1yi2:1, 1yij:1, 1yit:1, 1yj9:1, 1yjn:1, 1yjw:1
25 4v4n:Ae 62 49 0.2529 0.3548 0.4490 8.76e-07 4v6u:Be
26 8hku:L37E 54 52 0.2644 0.4259 0.4423 1.24e-06 8hkv:L37E, 8hky:L37E, 8hkz:L37E, 8hl1:L37E, 8hl2:L37E, 8hl3:L37E, 8hl4:L37E, 8hl5:L37E
27 6skf:Bh 62 51 0.2299 0.3226 0.3922 9.87e-05 6skg:Bh, 6th6:Bh
28 3cfd:H 220 47 0.1724 0.0682 0.3191 0.049 1cf8:H, 3cfd:B
29 3g5v:B 200 38 0.1379 0.0600 0.3158 0.57
30 9at8:L 121 33 0.1149 0.0826 0.3030 0.61
31 5tkk:H 213 33 0.1264 0.0516 0.3333 0.89
32 5bmf:H 216 33 0.1149 0.0463 0.3030 0.89 7eyc:H, 7eyc:A, 4lkx:A
33 1f90:H 220 33 0.1149 0.0455 0.3030 1.2 1kcr:H, 4ocx:H, 7yzj:H
34 1c12:B 220 33 0.1149 0.0455 0.3030 1.3
35 1ncw:H 222 33 0.1149 0.0450 0.3030 1.5 3g5y:B, 3lex:H, 3lex:A, 3ley:H, 1nd0:B, 1nd0:D, 1nd0:F, 1nd0:H
36 2ck0:H 211 53 0.1724 0.0711 0.2830 1.6 3ck0:H
37 4n8u:B 276 20 0.1149 0.0362 0.5000 1.8 4n8u:A, 4n8u:C
38 8x7u:D 654 29 0.1264 0.0168 0.3793 1.9 8x7u:E, 8x7u:C, 8x7u:B, 8x7u:F, 8x7u:A
39 3qg6:B 209 47 0.1494 0.0622 0.2766 2.5 3qg6:H
40 6o3l:H 223 33 0.1379 0.0538 0.3636 4.4 6o3l:A, 6o3u:H, 6o3u:B, 6o3u:D, 6o3u:F
41 8idy:u 554 38 0.1379 0.0217 0.3158 6.4 8inf:f, 8ink:N, 8ipy:N
42 8ib1:B 216 48 0.1724 0.0694 0.3125 6.4
43 4odt:H 226 53 0.1609 0.0619 0.2642 6.5 1cbv:H, 2hkf:H, 4z8f:H
44 3tas:B 301 32 0.1264 0.0365 0.3438 7.4 6fc7:A, 6fc7:B, 6fc7:C, 6fc7:D, 6fc7:E, 6fc7:F, 6fc7:G, 6fc7:H, 6fc7:I, 6fc7:J, 6fc7:L, 6fc7:K, 6fdj:A, 6fdj:B, 6fdj:C, 6fdj:D, 6fdj:F, 6fdj:E, 6fdj:G, 6fdj:I, 6fdj:H, 6fdj:J, 6fdj:K, 6fdj:L, 5lhl:A, 5lhl:B, 5lhl:C, 5lhl:D, 5lhl:F, 5lhl:E, 4m3h:A, 4m3h:B, 4m3h:C, 5mkm:A, 5mkm:B, 5mkm:C, 5mkm:D, 5mkm:E, 5mkm:F, 5o3k:A, 5o3k:C, 5o3k:B, 5o3k:D, 5o3k:E, 5o3k:F, 5o3k:G, 5o3k:H, 5o3k:I, 5o3k:J, 5o3k:K, 5o3k:L, 5o4i:A, 5o4i:B, 5o4i:C, 5o4i:D, 5o4i:E, 5o4i:F, 5o4i:G, 5o4i:H, 5o4i:I, 5o4i:J, 5o4i:K, 5o4i:L, 5o4q:A, 5o4q:B, 5o4q:C, 5o4q:D, 5o4q:E, 5o4q:F, 5o4q:G, 5o4q:H, 5o4q:I, 5o4q:J, 5o4q:K, 5o4q:L, 8p9u:A, 8p9u:C, 8p9u:B, 8p9u:D, 8p9u:F, 8p9u:E, 8p9v:A, 8p9v:B, 8p9v:C, 8p9v:D, 8p9v:E, 8p9v:F, 7pen:A, 7pen:B, 7pen:C, 7pen:D, 7pen:E, 7pen:F, 7pes:A, 7pes:B, 7pes:C, 7pes:D, 7pes:E, 7pes:F, 7pfr:A, 7pfr:B, 7pfr:C, 7pfr:D, 7pfr:E, 7pfr:F, 7ptm:A, 7ptm:C, 7ptm:B, 7ptm:D, 7ptm:F, 7ptm:E, 7pu0:A, 7pu0:B, 7pu0:C, 7pu0:D, 7pu0:E, 7pu0:F, 7puh:A, 7puh:C, 7puh:B, 7puh:D, 7puh:F, 7puh:E, 6rh9:A, 6rh9:B, 6rh9:C, 6rh9:D, 6rh9:E, 6rh9:F, 6rh9:G, 6rh9:H, 6rh9:I, 6rh9:J, 6rh9:K, 6rh9:L, 6rhq:A, 6rhq:B, 6rhq:C, 6rhq:D, 6rhq:E, 6rhq:F, 6s0o:A, 6s0o:B, 6s0o:C, 6s0o:D, 6s0o:E, 6s0o:F, 3tas:A, 3tas:C, 3tbb:A, 3tbb:B, 3tbb:C, 3tbc:A, 3tbc:B, 3tbc:C, 4uah:A, 4uah:B, 4uah:C, 4uan:A, 4uan:B, 4uan:C, 4w1t:A, 4w1t:B, 4w1t:C, 4wtq:A, 4wtq:B, 4wtq:C, 6y4a:AAA, 6y4a:BBB, 6y4a:CCC, 6yo5:AAA, 6yo5:BBB, 6yo5:CCC, 6yzd:AAA, 6yzd:BBB, 6yzd:CCC, 6yzf:CCC, 6yzf:AAA, 6yzf:BBB, 6yzy:AAA, 6yzy:BBB, 6yzy:CCC, 6zij:A, 6zij:C, 6zij:B, 6zij:D, 6zij:F, 6zij:E, 6zip:A, 6zip:B, 6zip:C, 6zip:D, 6zip:E, 6zip:F, 6zip:G, 6zip:H, 6zip:I, 6zip:J, 6zip:L, 6zip:K
45 1kc5:H 217 33 0.1034 0.0415 0.2727 7.5
46 3eyy:A 133 20 0.0920 0.0602 0.4000 8.1 3eyy:B
47 7alp:U 1935 58 0.1494 0.0067 0.2241 8.3
48 1f58:H 228 33 0.1149 0.0439 0.3030 8.4 5cp3:H, 2f58:H, 3f58:H, 5wtt:H, 5wtt:A, 2z92:A
49 4iqj:A 1164 32 0.1149 0.0086 0.3125 8.6
50 4iqj:D 1185 32 0.1149 0.0084 0.3125 8.6 3e0d:A, 3e0d:B, 2hpi:A, 2hpm:A, 4iqj:B, 4iqj:C
51 2cin:A 435 59 0.1724 0.0345 0.2542 8.6 2cjd:A, 2cjg:A, 2cjh:A, 2jje:A, 2jjg:A, 2jjh:A
52 7enc:0 306 29 0.1034 0.0294 0.3103 9.1 1g25:A, 8gxq:HD, 8gxs:HD, 6nmi:H, 7nvw:3, 7nvx:3, 7nvy:3, 7nvz:3, 8wak:0, 8wal:0, 8wan:0, 8wao:0, 8wap:0, 8waq:0, 8war:0, 8was:0
53 2ajs:H 219 46 0.1264 0.0502 0.2391 9.2 2ajv:H, 2ajx:H, 2ajy:H, 2ak1:H
54 7lbm:d 275 29 0.1034 0.0327 0.3103 9.6 8byq:7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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