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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TIYHAKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSCGTSTAYSVPCMFSYLGA
DEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLPKAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVA
ANNGKDMLIMLHQMGNHGPAYFKRYDEKFAKFTPVQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDVSMLYVSDHGES
LGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDAITPTLLKLFDVTADKVKDRTAFIR

The query sequence (length=312) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5yle:A 331 323 1.0000 0.9426 0.9659 0.0 5gov:B, 5gov:A, 5grr:A, 5k4p:A, 6li4:A, 6li4:B, 6li6:A, 6li6:B, 5lrm:A, 5lrn:A, 5lrn:B, 7yjp:A, 7yjp:B, 7yjq:A, 7yjq:B, 7yjr:A, 7yjr:B, 7yjs:A, 7yjs:B, 7yjt:A, 7yjt:B, 5ylc:A, 5ylf:A, 5zjv:A
2 6a7w:A 324 323 0.8686 0.8364 0.8390 0.0 6a7w:B, 5mx9:A, 6sut:A
3 6bnf:A 336 330 0.6891 0.6399 0.6515 2.36e-155 6bnc:A, 6bnc:B, 6bnd:A, 6bnd:B
4 5fgn:A 536 314 0.4071 0.2369 0.4045 6.93e-64 4kav:A, 4kay:A, 4kay:B
5 4tn0:A 308 310 0.3942 0.3994 0.3968 2.84e-62 4tn0:B, 4tn0:C
6 6a83:A 357 280 0.2212 0.1933 0.2464 5.35e-09 5zzu:A, 5zzu:B, 5zzu:C
7 7ebp:A 526 52 0.0513 0.0304 0.3077 0.047 7ebp:B, 7ebq:A
8 4upl:A 555 58 0.0513 0.0288 0.2759 0.13 4upl:C
9 7pth:A 517 81 0.0801 0.0484 0.3086 0.31 6fny:A, 6fny:B, 6fny:C, 6fny:D, 6fny:E, 6fny:F, 6fny:G, 6fny:H, 6g5z:A, 6g5z:B, 6g5z:C, 6g5z:D, 6g60:A, 6g60:B, 6g60:C, 6g60:D, 7pth:B, 7pth:C, 7pth:D, 7ptj:A, 7ptj:B, 7ptj:C, 7ptj:D
10 6j66:B 476 123 0.0994 0.0651 0.2520 0.76 6j66:A
11 4upi:A 548 60 0.0481 0.0274 0.2500 1.1
12 8qcf:K 915 96 0.0737 0.0251 0.2396 1.2
13 5egh:B 393 35 0.0417 0.0331 0.3714 2.5 5ege:A, 5ege:B, 5ege:C, 5ege:D, 5egh:A
14 4fw8:A 427 54 0.0449 0.0328 0.2593 3.4 4fw8:B, 4fw8:C, 4fw8:D, 3q6i:A, 3q6i:B, 3q6i:C, 3q6i:D, 3v1u:A
15 6hhm:A 459 52 0.0385 0.0261 0.2308 4.0
16 7l7x:AAA 395 74 0.0513 0.0405 0.2162 4.5 7l7x:BBB
17 5v13:A 268 75 0.0737 0.0858 0.3067 5.6 5v13:B, 5v13:C
18 6u7l:A 460 28 0.0321 0.0217 0.3571 5.9 6u7l:B, 6u7l:C, 6u7l:D
19 5g2v:A 494 52 0.0481 0.0304 0.2885 6.3
20 6jq9:B 483 101 0.0865 0.0559 0.2673 7.1 6byp:A, 6byp:B, 6byt:A, 6byt:B, 6byx:A, 6byx:B, 6jq9:A
21 2vqr:A 512 50 0.0385 0.0234 0.2400 7.5
22 4fai:B 305 90 0.0705 0.0721 0.2444 7.8 4fai:A, 4fbe:A, 4fbe:B
23 2w8s:B 513 50 0.0385 0.0234 0.2400 8.4 2w8s:A, 2w8s:C, 2w8s:D
24 4xgc:C 567 35 0.0417 0.0229 0.3714 8.4
25 7lj2:A 507 131 0.0929 0.0572 0.2214 9.0 7lha:A, 7lha:B, 7lj2:B
26 6gy5:A 285 125 0.0994 0.1088 0.2480 9.4
27 7jgs:C 614 35 0.0417 0.0212 0.3714 9.9 7jgr:C, 7jk2:C, 7jk3:C, 7jk4:C, 7jk5:C, 7jk6:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218