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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TITVLQGGNVLDLERGVLLEHHHVVIDGERIVEVTDRPVDLPNAQAIDVRGKTVMPGFIDCHVHVLASNANLGVNATQPN
ILAAIRSLPILDAMLSRGFTSVRDAGGADWSLMQAVETGLVSGPRIFPSGKALSQTGGHGDFRPRLEPCSCCFRTGAIAR
VVDGVEGVRLAVREEIQKGATQIKIMASGGVASPTDPIANTQYSEDEIRAIVDEAEAANTYVMAHAYTGRAIARAVRCGV
RTIEHGNLVDEAAAKLMHEHGAFVVPTLVTYDALAKHGAEFGMPPESVAKVASVQQKGRESLEIYANAGVKMGFGSDLLG
EMHAFQSGEFRIRAEVLGNLEALRSATTVAAEIVNMQGQLGVIAVGAIADLVVLDGNPLEDIGVVADEGARVEYVLQRGT
LVKRQ

The query sequence (length=405) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3n2c:A 408 408 1.0000 0.9926 0.9926 0.0 3feq:A, 3feq:B, 3feq:C, 3feq:D, 3feq:E, 3feq:F, 3feq:G, 3feq:H, 3feq:I, 3feq:J, 3feq:K, 3feq:L, 3feq:M, 3feq:N, 3feq:O, 3feq:P, 3n2c:B, 3n2c:C, 3n2c:D, 3n2c:E, 3n2c:F, 3n2c:G, 3n2c:H, 3n2c:I, 3n2c:J, 3n2c:K, 3n2c:L, 3n2c:M, 3n2c:N, 3n2c:O, 3n2c:P
2 3mkv:A 414 407 0.5827 0.5700 0.5799 1.21e-161 3mkv:B, 3mkv:C, 3mkv:D, 3mkv:E, 3mkv:F, 3mkv:G, 3mkv:H
3 8ihq:A 399 412 0.3481 0.3534 0.3422 9.19e-55 8ihq:B, 8ihq:C, 8ihq:D, 8ihq:E, 8ihq:F, 8ihq:G, 8ihq:H, 8ihr:A, 8ihr:B, 8ihr:C, 8ihr:D, 8ihr:E, 8ihr:F, 8ihr:G, 8ihr:H, 8ihs:A, 8ihs:B, 8ihs:C, 8ihs:D, 8ihs:E, 8ihs:F, 8ihs:G, 8ihs:H, 8j85:A, 8j85:B, 8j85:C, 8j85:D, 8j85:E, 8j85:F, 8j85:G, 8j85:H
4 2qs8:A 406 411 0.3235 0.3227 0.3187 1.32e-51 2qs8:B
5 3mtw:A 403 410 0.3136 0.3151 0.3098 7.33e-49
6 4c5y:A 436 371 0.3037 0.2821 0.3315 1.16e-43 4c5y:B
7 3be7:A 398 406 0.2741 0.2789 0.2734 1.63e-38 3be7:E, 3be7:B, 3be7:D, 3be7:C, 3be7:F, 3be7:G, 3be7:H, 3dug:A, 3dug:B, 3dug:C, 3dug:D, 3dug:E, 3dug:F, 3dug:G, 3dug:H
8 4ub9:A 467 438 0.2617 0.2270 0.2420 7.38e-10 4ub9:B, 4ub9:C, 4ub9:D, 4ub9:E, 4ub9:F, 4ub9:G, 4wgx:A
9 8je0:A 378 399 0.2074 0.2222 0.2105 1.49e-07 8je0:B, 8je0:C, 8je0:D
10 4whb:A 459 422 0.2346 0.2070 0.2251 1.65e-07
11 8dqn:C 388 83 0.0617 0.0644 0.3012 1.23e-04 8dqn:A, 8dqn:B, 8dqn:D, 8dqn:E, 8dqn:F, 8dqn:G, 8dqn:H
12 1onx:A 389 82 0.0642 0.0668 0.3171 2.13e-04 2aqo:A, 2aqo:B, 2aqv:A, 2aqv:B, 1onw:A, 1onw:B, 1onx:B, 1po9:A, 1po9:B, 1poj:A, 1poj:B, 1pok:B, 1pok:A, 1ybq:A, 1ybq:B
13 4bjh:A 422 62 0.0519 0.0498 0.3387 8.39e-04 3d6n:A
14 6gdd:A 375 62 0.0519 0.0560 0.3387 0.001 6gde:A, 6gdf:A, 1xrf:A, 1xrt:A, 1xrt:B
15 3du4:A 448 76 0.0642 0.0580 0.3421 0.003 3du4:B
16 6wnn:A 420 76 0.0642 0.0619 0.3421 0.003 3dod:A, 3dod:B, 6wnn:B
17 3icj:A 468 47 0.0444 0.0385 0.3830 0.007
18 1gkp:A 458 43 0.0420 0.0371 0.3953 0.008 1gkp:B, 1gkp:C, 1gkp:D, 1gkp:E, 1gkp:F, 1gkq:A, 1gkq:B, 1gkq:C, 1gkq:D
19 1gkp:A 458 31 0.0370 0.0328 0.4839 3.4 1gkp:B, 1gkp:C, 1gkp:D, 1gkp:E, 1gkp:F, 1gkq:A, 1gkq:B, 1gkq:C, 1gkq:D
20 3dc8:A 483 63 0.0568 0.0476 0.3651 0.015 3dc8:B
21 3dc8:A 483 56 0.0494 0.0414 0.3571 3.7 3dc8:B
22 4v1x:E 474 68 0.0716 0.0612 0.4265 0.016 4v1x:A, 4v1x:B, 4v1x:C, 4v1x:D, 4v1x:F, 4v1y:A, 4v1y:B, 4v1y:C, 4v1y:D, 4v1y:E, 4v1y:F, 4v1y:G, 4v1y:H, 4v1y:I, 4v1y:J, 4v1y:K, 4v1y:L
23 7bkb:G 568 71 0.0568 0.0405 0.3239 0.024 7bkb:g, 7bkc:G, 7bkc:g
24 5t5i:A 569 71 0.0593 0.0422 0.3380 0.026 5t5i:I, 5t5m:A, 5t61:A, 5t61:G, 5t61:M, 5t61:S, 5t61:Y, 5t61:e, 5t61:k, 5t61:q
25 7lkk:A 411 59 0.0494 0.0487 0.3390 0.044 7lkj:A, 7lkj:B, 7lkj:C, 7lkk:B, 7lkk:C, 7lkk:D
26 4f0r:A 436 208 0.1383 0.1284 0.2692 0.056 4f0s:A
27 3mpg:A 426 62 0.0519 0.0493 0.3387 0.057 3mpg:B, 4yiw:A, 4yiw:B
28 8is4:A 452 46 0.0444 0.0398 0.3913 0.058 8is4:B, 8is5:A, 8is5:B, 7ww2:A, 7ww2:B
29 5hmd:A 456 47 0.0444 0.0395 0.3830 0.061 5hmd:B, 5hme:A, 5hme:B, 5hmf:A, 5hmf:B, 4lh8:A, 4lh8:B, 3ls9:A, 3ls9:B, 3lsb:A, 3lsb:B, 3lsc:A, 3lsc:B
30 1m7j:A 474 63 0.0642 0.0549 0.4127 0.083 1rjp:A, 1rjq:A, 1rjr:A, 1rk5:A, 1rk6:A, 1v4y:A, 1v51:A
31 4kir:A 460 88 0.0617 0.0543 0.2841 0.14 4kir:B, 4kqn:A, 4kqn:B, 1yny:A, 1yny:B
32 4kir:A 460 76 0.0593 0.0522 0.3158 2.7 4kir:B, 4kqn:A, 4kqn:B, 1yny:A, 1yny:B
33 2oof:A 403 23 0.0296 0.0298 0.5217 0.17 2q09:A
34 3sfw:A 461 64 0.0469 0.0412 0.2969 0.24 3sfw:B
35 3sfw:A 461 76 0.0617 0.0542 0.3289 5.9 3sfw:B
36 1gkr:A 451 43 0.0395 0.0355 0.3721 0.25 1gkr:B, 1gkr:C, 1gkr:D
37 4gz7:A 492 62 0.0519 0.0427 0.3387 0.33 4h00:A, 4h01:A, 4lcq:A, 4lcr:A, 4lcs:A
38 2gok:A 404 33 0.0321 0.0322 0.3939 0.36 2gok:B, 2puz:A, 2puz:B
39 6ohb:A 435 21 0.0272 0.0253 0.5238 0.36 6ohb:B, 6ohb:C, 6ohb:D, 6ohc:A, 6ohc:B, 6ohc:C, 6ohc:D
40 3gri:B 423 49 0.0444 0.0426 0.3673 0.43 3gri:A
41 2vun:A 385 26 0.0346 0.0364 0.5385 0.54 2vun:B, 2vun:C, 2vun:D
42 4cqb:A 402 46 0.0370 0.0373 0.3261 0.73 5akq:A, 5akq:B, 4cqb:B, 4cqc:A, 4cqc:B, 4cqd:A, 4cqd:B, 2qt3:A, 2qt3:B
43 4dyk:A 437 102 0.0815 0.0755 0.3235 0.92 4dyk:B, 4gbd:A, 4gbd:B
44 4tqt:D 481 62 0.0494 0.0416 0.3226 0.94 4tqt:A, 4tqt:B, 4tqt:C, 4tqt:E, 4tqt:F
45 4x7g:A 251 90 0.0642 0.1036 0.2889 1.00 5c4n:D
46 6k76:A 485 42 0.0370 0.0309 0.3571 1.1 6k76:B
47 3nqb:A 587 65 0.0543 0.0375 0.3385 1.3 3nqb:B, 3t81:A, 3t81:B
48 6jku:A 385 43 0.0420 0.0442 0.3953 1.4 6jku:B, 6jku:C, 6jku:D
49 2i9u:A 419 58 0.0420 0.0406 0.2931 1.4 2i9u:B
50 5xgx:A 381 65 0.0444 0.0472 0.2769 1.5 5xgw:A, 5xgw:B, 5xgx:B
51 7cf6:A 384 379 0.2123 0.2240 0.2269 1.8 7cdh:X, 7cf6:B, 7cf6:C, 7cf6:D
52 3gip:A 474 23 0.0321 0.0274 0.5652 1.9 3gip:B, 3giq:A, 3giq:B
53 8a6t:C 151 125 0.0914 0.2450 0.2960 2.7 8a6t:F, 8bew:C, 8bew:F
54 5g0y:B 377 127 0.0840 0.0902 0.2677 2.7 5g0x:A, 5g0x:C, 5g0y:A, 5g10:A, 5g10:B, 5g11:A, 5g11:B, 5g12:A, 5g12:B, 5g13:A, 5g13:B, 5li3:A, 5li3:B
55 3iv8:A 379 49 0.0420 0.0449 0.3469 3.0
56 3iv8:A 379 35 0.0395 0.0422 0.4571 3.4
57 1nfg:A 457 30 0.0321 0.0284 0.4333 3.8 1nfg:B, 1nfg:C, 1nfg:D
58 2vr2:A 478 29 0.0346 0.0293 0.4828 4.4
59 3wwh:A 329 48 0.0444 0.0547 0.3750 4.7 5fr9:A, 5fr9:B, 5fr9:C, 5fr9:D, 5fr9:E, 5fr9:F, 5fr9:G, 5fr9:H, 5fr9:I, 5fr9:J, 5fr9:K, 5fr9:L, 3wwi:A, 3wwi:B, 3wwi:C, 3wwi:D, 3wwi:E, 3wwi:F, 3wwi:G, 3wwi:H, 3wwi:I, 3wwi:J, 3wwi:K, 3wwi:L, 3wwj:A, 3wwj:B, 3wwj:C, 3wwj:D, 3wwj:E, 3wwj:F, 3wwj:G, 3wwj:H, 3wwj:I, 3wwj:J, 3wwj:K, 3wwj:L
60 3hpa:A 428 117 0.0741 0.0701 0.2564 6.4 3hpa:B
61 6fv3:D 350 193 0.1333 0.1543 0.2798 6.5
62 1k1d:A 460 46 0.0370 0.0326 0.3261 6.6 1k1d:B, 1k1d:C, 1k1d:D, 1k1d:E, 1k1d:F, 1k1d:G, 1k1d:H
63 2ivn:A 325 54 0.0370 0.0462 0.2778 8.4 2ivo:A, 2ivo:B, 2ivo:C, 2ivp:A
64 6s2v:C 336 71 0.0593 0.0714 0.3380 8.7 6s2v:B
65 7uof:A 423 20 0.0247 0.0236 0.5000 8.8
66 3lnp:A 441 53 0.0296 0.0272 0.2264 8.8
67 7ohg:A 351 71 0.0593 0.0684 0.3380 8.9 6s2t:A, 6s2u:A, 6s2v:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218