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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TISPPEREAKAKVSVDNNPVPTSFEKWGKPGHFDRTLARGPKTTTWIWNLHANAHDFDSQTSDLEDVSRKIFSAHFGHLA
VVFVWLSGMYFHGAKFSNYEGWLADPTHIKPSAQVVWPIVGQGILNGDVGGGFHGIQITSGLFYLWRASGFTDSYQLYCT
AIGGLVMAALMLFAGWFHYHVKAPKLEWFQNVESMMNHHLAGLLGLGSLGWAGHQIHVSMPINKLLDAGVAPKDIPLPHE
FILEPSKMAELYPSFAQGLTPFFTLNWGVYSDFLTFKGGLNPVTGGLWLSDTAHHHLAIAVLFIIAGHMYRTNWGIGHSM
KEILEAHKGPFTGEGHKGLYEILTTSWHAQLAINLALLGSLTIIVAQHMYAMPPYPYQAIDYATQLSLFTHHMWIGGFLI
VGAGAHGAIFMVRDYDPAKNVNNLLDRMLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMRALGRPQDMFSDTAIQLQPI
FAQWVQHLHTLAPGATAPNALATASYAFGGETIAVAGKVAMMPITLGTADFMVHHIHAFTIHVTALILLKGVLYARSSRL
VPDKANLGFRFPCDGPGRGGTCQVSGWDHVFLGLFWMYNSLSIVIFHFSWKMQSDVWGTVSPDGSVTHVTLGNFAQSAIT
INGWLRDFLWAQAANVINSYGSALSAYGIMFLAGHFVFAFSLMFLFSGRGYWQELIESIVWAHNKLNVAPAIQPRALSII
QGRAVGVAHYLLGGIVTTWAFFLARSLSIG

The query sequence (length=750) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5oy0:A 751 750 1.0000 0.9987 1.0000 0.0 8am5:a, 8asl:a, 8asp:a, 6hqb:A, 4kt0:A, 4l6v:A, 4l6v:a, 4l6v:1, 6nwa:A, 6nwa:a, 6nwa:H, 7o1v:A, 5oy0:a, 5oy0:1, 7umh:A, 7umh:H, 7umh:a, 6uzv:A, 6uzv:a, 6uzv:1, 6vpv:A, 6vpv:a, 6vpv:1
2 6tra:A 746 745 0.8680 0.8727 0.8738 0.0 4fe1:A, 7fix:A1, 7fix:A2, 7fix:A3, 1jb0:A, 6k33:aA, 6k33:bA, 6k33:cA, 6lu1:A, 7m75:A, 7m76:A, 7m78:A, 3pcq:A, 6pfy:A, 6pfy:G, 6pfy:Y, 6pgk:A, 6pgk:G, 6pgk:Y, 6trc:A, 6trc:a, 6trc:1, 6trd:A, 6trd:a, 6trd:1, 5zf0:A1, 5zf0:A2, 5zf0:A3, 5zf0:A4, 5zf0:A6, 5zf0:A5
3 6k61:A 742 741 0.8360 0.8450 0.8462 0.0 6jeo:aA, 6jeo:bA, 6jeo:cA, 6jeo:dA, 6k61:a, 6tcl:A1, 6tcl:A2, 6tcl:A, 6tcl:AA, 7y3f:A
4 7y5e:AN 745 745 0.8347 0.8403 0.8403 0.0 7y5e:A2, 7y7a:A7, 7y7a:Ao
5 6kif:A 751 752 0.8400 0.8389 0.8378 0.0 6kif:G, 6kif:e, 6kig:A, 6kig:G, 6kig:e
6 7dr0:A 739 739 0.8133 0.8254 0.8254 0.0 7dr1:A, 7dr2:aA, 7dr2:bA, 7dr2:cA, 7dr2:dA
7 8wm6:A 742 741 0.8000 0.8086 0.8097 0.0 8wmj:A, 8wmv:A, 8wmw:A, 7y7b:A, 7y8a:A
8 7blz:A 743 730 0.8160 0.8237 0.8384 0.0 6fos:A, 8wey:A, 5zgb:A, 5zgh:A
9 7yca:A 742 739 0.8080 0.8167 0.8200 0.0 7a4p:A, 7bgi:A, 7blx:A, 8cmo:A, 7d0j:A, 7dz7:A, 7dz8:A, 8h2u:A, 6ijj:A, 6ijo:A, 6jo5:A, 6jo6:A, 7r3k:A, 7wyi:A, 7wzn:A, 7zq9:A, 7zqc:A, 7zqd:A, 7zqd:A2, 6zzx:A, 6zzy:A
10 6ly5:a 742 740 0.7987 0.8073 0.8095 0.0 6l4u:A
11 7qco:A 728 728 0.8080 0.8324 0.8324 0.0 7qco:E, 7qco:e, 7qco:a
12 5l8r:A 743 742 0.7933 0.8008 0.8019 0.0 8bcv:A, 8bcw:A, 7dkz:A, 7ew6:A, 7ewk:A, 7f9o:A, 7f9o:e, 8htu:A, 8j6z:A, 8j7a:A, 8j7b:A, 7ksq:A, 7kux:A, 6l35:A, 3lw5:A, 2o01:A, 4rku:A, 7wfd:AA, 7wfe:BA, 7wg5:AA, 7wg5:BA, 8wgh:A, 2wsc:A, 2wse:A, 2wsf:A, 4xk8:A, 4xk8:a, 7xqp:A, 4y28:A, 6yac:A, 6yez:A, 5zji:A, 6zoo:A, 6zxs:A
13 6igz:A 740 741 0.8120 0.8230 0.8219 0.0 6qph:A, 6rhz:A, 6sl5:A, 6yxr:A
14 7s3d:A 749 749 0.7907 0.7917 0.7917 0.0 7s3d:G, 7s3d:a
15 6kmw:aA 721 721 0.7907 0.8225 0.8225 0.0 6kmw:bA, 6kmw:cA
16 7lx0:G 751 753 0.7920 0.7909 0.7888 0.0 7lx0:a, 7lx0:A, 6pnj:A, 6pnj:G, 6pnj:a
17 7dwq:A 726 724 0.7347 0.7590 0.7610 0.0
18 7coy:aA 685 713 0.7013 0.7679 0.7377 0.0 7coy:bA, 7coy:cA
19 6kmx:aA 717 717 0.7200 0.7531 0.7531 0.0 6kmx:bA, 6kmx:cA
20 7f4v:aA 772 773 0.7293 0.7085 0.7076 0.0 7f4v:bA, 7f4v:cA
21 8jjr:a 665 724 0.4613 0.5203 0.4779 0.0
22 8jze:a 670 725 0.4440 0.4970 0.4593 0.0 8jzf:a
23 7f4v:aB 725 747 0.4653 0.4814 0.4672 0.0 7f4v:bB, 7f4v:cB
24 6kmw:aB 740 765 0.4653 0.4716 0.4562 0.0 6kmw:cB, 6kmw:bB
25 7blz:B 731 753 0.4547 0.4665 0.4529 0.0 6fos:B, 8wey:B, 5zgb:B, 5zgh:B
26 6ly5:b 732 754 0.4507 0.4617 0.4483 0.0 6l4u:B
27 7y5e:BN 732 755 0.4520 0.4631 0.4490 0.0 7y5e:B2, 7y7a:B7, 7y7a:Bo, 7y7b:B, 7y8a:B
28 6vpv:B 737 759 0.4533 0.4613 0.4480 0.0 8am5:b, 8asl:b, 8asp:b, 6hqb:B, 4kt0:B, 4l6v:B, 4l6v:b, 4l6v:2, 6nwa:B, 6nwa:b, 6nwa:G, 7o1v:B, 5oy0:B, 5oy0:b, 5oy0:2, 7umh:B, 7umh:G, 7umh:b, 6uzv:B, 6uzv:b, 6uzv:2, 6vpv:b, 6vpv:2
29 8jw0:a 645 709 0.4667 0.5426 0.4937 0.0
30 6kif:B 733 756 0.4573 0.4679 0.4537 0.0 6kif:H, 6kif:f, 6kig:B, 6kig:H, 6kig:f
31 7d0j:B 734 755 0.4440 0.4537 0.4411 0.0 7a4p:B, 7bgi:B, 7blx:B, 8cmo:B, 7dz7:B, 7dz8:B, 8h2u:B, 6ijj:B, 6ijo:B, 6jo5:B, 6jo6:B, 6qph:B, 7r3k:B, 6rhz:B, 6sl5:B, 7wyi:B, 7wzn:B, 6yxr:B, 7zq9:B, 7zqc:B, 7zqd:B, 7zqd:B2, 6zzx:B, 6zzy:B
32 7fix:B1 740 763 0.4533 0.4595 0.4456 0.0 7bw2:B, 4fe1:B, 7fix:B2, 7fix:B3, 1jb0:B, 6k33:aB, 6k33:bB, 6k33:cB, 7m75:B, 7m76:B, 7m78:B, 3pcq:B, 6pfy:H, 6pfy:B, 6pfy:Z, 6pgk:H, 6pgk:B, 6pgk:Z, 6tra:B, 6trc:B, 6trc:b, 6trc:2, 6trd:B, 6trd:b, 6trd:2, 5zf0:B1, 5zf0:B2, 5zf0:B3, 5zf0:B4, 5zf0:B6, 5zf0:B5
33 6igz:B 733 740 0.4400 0.4502 0.4459 0.0
34 8wm6:B 732 760 0.4453 0.4563 0.4395 0.0 8wmj:B, 8wmv:B, 8wmw:B
35 7s3d:B 742 766 0.4373 0.4420 0.4282 0.0 7s3d:H, 7s3d:b
36 6kmx:aB 727 757 0.4387 0.4525 0.4346 0.0 6kmx:bB, 6kmx:cB
37 7yca:B 732 755 0.4373 0.4481 0.4344 0.0
38 7qco:B 734 759 0.4347 0.4441 0.4295 0.0 7qco:G, 7qco:g, 7qco:b
39 7wfd:AB 734 739 0.4373 0.4469 0.4438 0.0 8bcv:B, 8bcw:B, 7dkz:B, 7ew6:B, 7ewk:B, 7f9o:B, 7f9o:f, 8htu:B, 8j6z:B, 8j7a:B, 8j7b:B, 7ksq:B, 7kux:B, 6l35:B, 5l8r:B, 3lw5:B, 2o01:B, 4rku:B, 7wfe:BB, 7wg5:AB, 7wg5:BB, 8wgh:B, 2wsc:B, 2wse:B, 2wsf:B, 4xk8:B, 4xk8:b, 7xqp:B, 4y28:B, 6yac:B, 6yez:B, 5zji:B, 6zoo:B, 6zxs:B
40 6k61:B 740 763 0.4413 0.4473 0.4338 0.0 6jeo:aB, 6jeo:bB, 6jeo:cB, 6jeo:dB, 6k61:b, 6tcl:B1, 6tcl:B2, 6tcl:B, 6tcl:BB, 7y3f:B
41 6lu1:B 713 756 0.4387 0.4614 0.4352 0.0
42 7lx0:H 739 767 0.4307 0.4371 0.4211 0.0 7lx0:b, 7lx0:B, 6pnj:H, 6pnj:B, 6pnj:b
43 7dr0:B 706 764 0.4267 0.4533 0.4188 0.0 7dr1:B, 7dr2:aB, 7dr2:bB, 7dr2:cB, 7dr2:dB
44 7dwq:B 659 752 0.4080 0.4643 0.4069 4.18e-175 7coy:aB, 7coy:bB, 7coy:cB
45 8jw0:b 617 714 0.2960 0.3598 0.3109 3.97e-99
46 8jze:b 663 711 0.3013 0.3409 0.3179 5.56e-93 8jzf:b
47 8jjr:b 659 746 0.3067 0.3490 0.3083 1.24e-92
48 5v8k:A 600 224 0.0787 0.0983 0.2634 5.20e-13
49 7zq9:B2 180 192 0.0760 0.3167 0.2969 1.68e-12
50 6m32:A 628 230 0.0747 0.0892 0.2435 0.003 6m32:a
51 8gwa:A 667 230 0.0747 0.0840 0.2435 0.003 8gwa:a, 7uea:A, 7uea:a, 7ueb:A, 7ueb:a, 7z6q:A, 7z6q:a
52 7vzg:a 858 120 0.0400 0.0350 0.2500 0.16 7vzg:A, 7vzr:A, 7vzr:a
53 1ofd:A 1491 153 0.0480 0.0241 0.2353 0.72 1ofd:B, 1ofe:A, 1ofe:B
54 8abs:A 394 63 0.0280 0.0533 0.3333 1.3 8abr:A, 5ofq:A, 5ofq:B, 5ofq:C, 5ofq:D
55 8shj:C 306 90 0.0253 0.0621 0.2111 3.8 8t55:C
56 8d0b:A 1116 95 0.0387 0.0260 0.3053 5.3 8d0k:A
57 3vkg:B 2853 66 0.0320 0.0084 0.3636 6.2
58 3vkh:B 2908 66 0.0320 0.0083 0.3636 6.2
59 2qxg:A 224 54 0.0293 0.0982 0.4074 6.9 5fah:A, 2qxg:B, 2qxh:A, 2qxi:A, 2qxj:A, 6shh:A, 6shh:B, 6shh:C, 6shh:D, 6shh:H, 6shh:E, 6shh:F, 6shh:G, 6shi:A, 6shi:B, 6shi:C, 6shi:E, 6shi:D, 6shi:H, 6shi:F, 6shi:G, 6sju:A, 6sju:B, 6sju:C, 6sju:E, 6sju:D, 6sju:H, 6sju:F, 6sju:G, 5y9l:A, 5yjk:A
60 1llw:A 1475 153 0.0453 0.0231 0.2222 9.3 1llz:A, 1lm1:A
61 1ytm:A 517 95 0.0267 0.0387 0.2105 9.5 1ytm:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218