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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TISKNNKMMAHLNYRMKIILQDGRTFIGFFKAFDKHMNILLAECEEHRQIEEKRILGLVLVRGEHIVSMTVDGPPPRDGG
AGGVGQAKPGGRGMPAMP

The query sequence (length=98) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ro0:b 98 98 1.0000 1.0000 1.0000 1.59e-69 8ro1:b
2 7w59:b 102 103 0.6224 0.5980 0.5922 1.04e-39 7abg:m, 7abi:m, 6ahd:a, 7b0y:j, 8c6j:b, 8ch6:8, 7dvq:i, 9fmd:i, 8h6e:5a, 8h6e:4a, 8h6j:5a, 8h6j:4a, 8h6k:5a, 8h6l:5a, 8i0p:a, 8i0p:m, 8i0r:a, 8i0r:m, 8i0s:m, 8i0t:a, 8i0t:m, 8i0u:m, 8i0v:a, 8i0v:m, 8i0w:a, 8i0w:i, 6icz:i, 4pjo:B, 4pjo:b, 4pjo:P, 4pjo:p, 8q7q:b, 8q7v:b, 8q7w:b, 8q7x:b, 8q91:h, 6qdv:k, 8qo9:5b, 8qo9:4b, 6qw6:4b, 6qw6:5b, 6qx9:1b, 6qx9:5b, 6qx9:2b, 6qx9:4b, 8qxd:4b, 8qxd:5b, 8qzs:5b, 8qzs:2b, 8r08:1b, 8r08:4b, 8r08:5b, 8r09:5b, 8r0a:5b, 8r0b:5b, 8rc0:h, 8rm5:2b, 8rm5:5b, 8ro2:b, 7vpx:k, 7w59:i, 7w5a:b, 7w5a:i, 7w5b:b, 7w5b:i, 4wzj:B, 5xjc:b, 5xjc:i, 8y6o:a, 8y6o:h, 8y6o:o, 8y7e:i, 5yzg:b, 5yzg:i, 5z56:b, 5z56:i, 5z57:b, 5z57:i, 5z58:b, 5z58:i
3 6v4x:B 76 76 0.5204 0.6711 0.6711 1.59e-36
4 3jb9:E 98 91 0.4694 0.4694 0.5055 2.44e-27 3jb9:b
5 9fmd:b 87 68 0.4388 0.4943 0.6324 5.48e-27 7a5p:m, 7a5p:b, 7abg:f, 7abi:f, 6ah0:U, 8ch6:n, 5o9z:f, 6qdv:b, 7qtt:n, 4wzj:I, 4wzj:P, 4wzj:BB, 4wzj:II, 4wzj:PP, 4wzj:BBB, 4wzj:III, 4wzj:PPP, 4wzj:BBBB, 4wzj:IIII, 4wzj:PPPP
6 6bk8:f 80 77 0.3367 0.4125 0.4286 1.78e-18 6bk8:k, 7dco:a, 7dco:h, 6exn:k, 6exn:b, 6g90:s, 5gam:b, 5gan:k, 5gan:b, 5gao:k, 5gm6:k, 5gmk:k, 5gmk:s, 3jcm:S, 5lj3:b, 5lj5:b, 5mps:b, 5mq0:k, 5mq0:b, 5nrl:s, 5nrl:k, 5nrl:b, 7oqb:s, 7oqe:s, 5wsg:k, 5wsg:F, 5y88:a, 5y88:h, 5ylz:a, 5ylz:h, 5zwm:P, 5zwm:a, 5zwm:h, 5zwo:a, 5zwo:P
7 6n7r:K 124 91 0.3367 0.2661 0.3626 1.53e-16 7b9v:k, 7b9v:b, 6g90:b, 6j6g:k, 6j6g:s, 6j6h:k, 6j6h:s, 6j6n:k, 6j6n:s, 6j6q:k, 6j6q:s, 6n7p:K, 6n7x:K, 7oqc:b, 7oqe:b, 8w2o:K, 5zwn:a
8 1loj:C 77 59 0.2653 0.3377 0.4407 6.91e-09 1loj:A, 1loj:B, 1loj:D, 1loj:E, 1loj:F, 1loj:G, 1loj:H, 1loj:I, 1loj:J, 1loj:K, 1loj:L, 1loj:M, 1loj:N
9 6qw6:68 95 60 0.2143 0.2211 0.3500 3.65e-07 6ahd:z, 8h6e:6g, 8h6j:6g, 8h6k:6g, 8h6l:6g, 6qx9:68, 8qxd:68, 8r08:68, 8r09:68, 8r0a:68, 8r0b:68, 8rm5:68
10 1i5l:C 74 51 0.1939 0.2568 0.3725 1.08e-05 1i5l:E, 1i5l:F, 1i5l:G, 1i5l:J, 1i5l:K, 1i5l:L, 1i5l:A, 1i5l:B, 1i5l:H
11 5vsu:C 81 64 0.2041 0.2469 0.3125 1.76e-04 6aso:C, 4c8q:C, 5gan:3, 4m7a:J, 4m7a:C, 4m7d:J, 4m7d:C, 5nrl:3
12 5mkn:d 72 62 0.1939 0.2639 0.3065 2.49e-04 5mki:C, 5mki:D, 5mki:E, 5mki:F, 5mki:G, 5mki:I, 5mki:J, 5mki:K, 5mki:L, 5mkn:A, 5mkn:G, 5mkn:B, 5mkn:C, 5mkn:D, 5mkn:E, 5mkn:F, 5mkn:H, 5mkn:I, 5mkn:J, 5mkn:K, 5mkn:L, 5mkn:M, 5mkn:N, 5mkn:O, 5mkn:P, 5mkn:Q, 5mkn:R, 5mkn:T, 5mkn:U, 5mkn:V, 5mkn:W, 5mkn:X, 5mkn:Y, 5mkn:Z, 5mkn:a, 5mkn:b
13 6v4x:G 77 58 0.1633 0.2078 0.2759 3.25e-04 7a5p:k, 7a5p:g, 7abg:k, 7abi:k, 6ah0:n, 6ahd:S, 6ahd:f, 6ahd:n, 7b0y:h, 8c6j:r, 8c6j:g, 8ch6:m, 8ch6:9, 7dvq:g, 7dvq:n, 7evo:d, 9fmd:n, 9fmd:g, 8h6e:5f, 8h6e:4f, 8h6e:2f, 8h6j:5f, 8h6j:4f, 8h6j:2f, 8h6k:5f, 8h6k:4f, 8h6k:2f, 8h6l:5f, 8h6l:4f, 8h6l:2f, 8hk1:d, 8i0p:k, 8i0r:k, 8i0s:f, 8i0s:k, 8i0t:k, 8i0u:f, 8i0u:k, 8i0v:k, 8i0w:n, 6icz:g, 6id0:g, 6id1:g, 5mqf:k, 5mqf:d, 5o9z:k, 4pjo:G, 4pjo:g, 4pjo:U, 4pjo:u, 8q7q:g, 8q7v:g, 8q7w:g, 8q7x:g, 8q91:n, 6qdv:r, 6qdv:g, 8qo9:2g, 8qo9:4g, 7qtt:m, 6qw6:4g, 6qw6:5g, 6qx9:1g, 6qx9:5g, 6qx9:2g, 6qx9:4g, 8qxd:2g, 8qxd:4g, 8qxd:5g, 8qzs:5g, 8qzs:2g, 8qzs:4g, 8r08:1g, 8r08:2g, 8r08:4g, 8r08:5g, 8r09:2g, 8r09:5g, 8r09:4g, 8r0a:5g, 8r0a:2g, 8r0a:4g, 8r0b:2g, 8r0b:4g, 8r0b:5g, 8rc0:n, 8rm5:2g, 8rm5:5g, 8rm5:4g, 8ro2:g, 7vpx:d, 7vpx:n, 7w59:g, 7w59:n, 7w5a:g, 7w5a:n, 7w5b:g, 7w5b:n, 4wzj:G, 4wzj:N, 4wzj:U, 4wzj:GG, 4wzj:NN, 4wzj:UU, 4wzj:GGG, 4wzj:NNN, 4wzj:UUU, 4wzj:GGGG, 4wzj:NNNN, 4wzj:UUUU, 5xjc:g, 5xjc:n, 6y53:k, 6y5q:k, 8y6o:g, 8y6o:n, 8y6o:u, 8y7e:n, 5yzg:g, 5yzg:n, 5z56:g, 5z56:n, 5z57:g, 5z57:n, 5z58:g, 5z58:n
14 6ppn:H 94 56 0.2041 0.2128 0.3571 4.69e-04 6ppn:P, 6ppp:H, 6ppp:P
15 6ppq:A 69 68 0.1735 0.2464 0.2500 5.67e-04 6ppv:A
16 1m8v:A 72 59 0.1633 0.2222 0.2712 0.003 1m8v:M, 1m8v:C, 1m8v:K, 1m8v:F, 1m8v:H, 1m8v:E, 1m8v:I, 1m8v:D, 1m8v:J, 1m8v:B, 1m8v:L, 1m8v:G, 1m8v:N
17 8ro0:n 77 59 0.1633 0.2078 0.2712 0.003 8ro0:g, 8ro1:g
18 8ro0:d 94 64 0.1633 0.1702 0.2500 0.009 8ro1:d
19 1lnx:A 74 53 0.1735 0.2297 0.3208 0.019 1lnx:B, 1lnx:C, 1lnx:D, 1lnx:E, 1lnx:F, 1lnx:G
20 8y6o:q 104 60 0.1429 0.1346 0.2333 0.030 7a5p:h, 7abg:a, 7abi:a, 6ah0:k, 6ah0:P, 6ahd:P, 6ahd:k, 8ch6:l, 8ch6:4, 7dvq:k, 8h6e:2c, 8h6j:2c, 8h6k:4c, 8h6k:2c, 8h6l:4c, 8h6l:2c, 8i0w:k, 6id0:k, 6id1:k, 5o9z:h, 5o9z:a, 4pjo:R, 7qtt:l, 8qzs:42, 7w59:k, 7w5a:k, 7w5b:k, 5xjc:k, 8y7e:k, 5yzg:k, 5z56:k, 5z57:k, 5z58:k
21 6tfl:A 62 58 0.1531 0.2419 0.2586 0.033 6tfl:B, 6tfl:C, 6tfl:D, 6tfl:E, 6tfl:F, 6tfl:G, 6tfl:H, 6tfl:I, 6tfl:J, 6tfl:K, 6tfl:L, 6tfl:M, 6tfl:N
22 6ppq:F 71 56 0.1327 0.1831 0.2321 0.049 6ppn:F, 6ppn:N, 6ppp:F, 6ppp:N, 6ppv:F
23 6qw6:66 72 51 0.1429 0.1944 0.2745 0.060 6qx9:66
24 8ro0:f 72 48 0.1531 0.2083 0.3125 0.068 8ro1:f
25 3jb9:J 73 60 0.1531 0.2055 0.2500 0.081 3jb9:o
26 5vsu:H 100 69 0.2041 0.2000 0.2899 0.084 5gan:8, 4m7a:H, 4m7a:A, 4m7d:H, 4m7d:A, 5nrl:8, 5zwo:z
27 6qw6:63 85 77 0.2143 0.2471 0.2727 0.088 6ah0:r, 6qx9:63, 8qxd:63, 8r08:63, 8r09:63, 8r0a:63, 8r0b:63, 8rm5:63
28 7abg:j 81 40 0.1327 0.1605 0.3250 0.094 7a5p:j, 7a5p:e, 7abi:j, 6ah0:c, 6ahd:e, 7b0y:g, 8c6j:p, 8c6j:e, 8ch6:i, 8ch6:1, 7dvq:e, 7dvq:l, 9fmd:l, 9fmd:e, 8h6e:5e, 8h6e:4e, 8h6j:5e, 8h6j:4e, 8h6k:5e, 8h6l:5e, 8i0p:e, 8i0p:j, 8i0r:e, 8i0r:j, 8i0s:e, 8i0s:j, 8i0t:e, 8i0t:j, 8i0u:e, 8i0u:j, 8i0v:e, 8i0v:j, 8i0w:e, 8i0w:l, 6icz:e, 6id0:e, 6id1:e, 5mqf:j, 5mqf:c, 5o9z:j, 4pjo:E, 4pjo:e, 4pjo:S, 4pjo:s, 8q7q:e, 8q7v:e, 8q7w:e, 8q7x:e, 6qdv:p, 6qdv:e, 8qo9:2e, 8qo9:5e, 8qo9:4e, 7qtt:i, 6qw6:4e, 6qw6:5e, 6qx9:1e, 6qx9:5e, 6qx9:2e, 6qx9:4e, 8qxd:2e, 8qxd:4e, 8qzs:5e, 8qzs:2e, 8qzs:4e, 8r08:1e, 8r08:2e, 8r08:4e, 8r09:2e, 8r09:5e, 8r09:4e, 8r0a:5e, 8r0a:2e, 8r0a:4e, 8r0b:4e, 8r0b:5e, 8rm5:2e, 8rm5:5e, 8rm5:4e, 8ro2:e, 6v4x:E, 7vpx:l, 7w59:e, 7w59:l, 7w5a:e, 7w5a:l, 7w5b:e, 7w5b:l, 4wzj:E, 4wzj:L, 4wzj:S, 4wzj:EE, 4wzj:LL, 4wzj:SS, 4wzj:EEE, 4wzj:LLL, 4wzj:SSS, 4wzj:EEEE, 4wzj:LLLL, 4wzj:SSSS, 5xjc:e, 5xjc:l, 8y6o:e, 8y6o:l, 8y6o:s, 8y7e:l, 5yzg:e, 5yzg:l, 5z56:e, 5z56:l, 5z57:e, 5z57:l, 5z58:e, 5z58:l
29 3swn:A 76 36 0.1020 0.1316 0.2778 0.31 6ppq:E, 6ppv:E, 3swn:D, 3swn:P, 3swn:S
30 6n7p:M 107 57 0.1531 0.1402 0.2632 0.33 7b9v:m, 7b9v:j, 6bk8:a, 7dco:n, 6exn:m, 6exn:j, 6g90:i, 6g90:u, 5gam:j, 5gan:m, 5gan:j, 5gao:m, 5gm6:g, 5gmk:g, 5gmk:e, 6j6g:g, 6j6g:e, 6j6h:g, 6j6h:e, 6j6n:g, 6j6n:e, 6j6q:g, 6j6q:e, 3jcm:Q, 3jcm:U, 5lj3:j, 5lj3:m, 5lj5:j, 5lj5:m, 5mps:j, 5mq0:j, 6n7r:M, 6n7x:M, 5nrl:u, 5nrl:m, 5nrl:i, 7oqb:u, 7oqc:i, 7oqe:i, 7oqe:u, 8w2o:M, 5wsg:g, 5wsg:W, 5y88:g, 5y88:n, 5ylz:g, 5ylz:n, 5zwm:R, 5zwm:c, 5zwm:n, 5zwn:c, 5zwo:c, 5zwo:R, 5zwo:n
31 3jb9:H 76 70 0.1939 0.2500 0.2714 0.35 3jb9:m
32 6aso:H 83 56 0.1735 0.2048 0.3036 0.50
33 4wzj:MM 80 50 0.1531 0.1875 0.3000 0.55 7abg:b, 7abi:b, 6ahd:Q, 6ahd:d, 7b0y:f, 8c6j:q, 8c6j:f, 8ch6:h, 8ch6:2, 7dvq:f, 7dvq:m, 9fmd:m, 9fmd:f, 8h6e:5d, 8h6e:4d, 8h6j:5d, 8h6j:4d, 8h6k:5d, 8h6k:4d, 8h6l:5d, 8h6l:4d, 8i0p:d, 8i0r:d, 8i0s:d, 8i0s:i, 8i0t:d, 8i0t:i, 8i0u:d, 8i0u:i, 8i0v:d, 8i0v:i, 8i0w:d, 8i0w:m, 6id1:f, 5mqf:i, 5mqf:b, 5o9z:i, 4pjo:F, 4pjo:f, 4pjo:T, 4pjo:t, 8q7q:f, 8q7v:f, 8q7w:f, 8q7x:f, 8q91:m, 6qdv:q, 6qdv:f, 8qo9:2f, 8qo9:5f, 8qo9:4f, 7qtt:h, 6qw6:4f, 6qw6:5f, 6qx9:1f, 6qx9:5f, 6qx9:2f, 6qx9:4f, 8qxd:2f, 8qxd:4f, 8qxd:5f, 8qzs:5f, 8qzs:2f, 8qzs:4f, 8r08:1f, 8r08:2f, 8r08:4f, 8r08:5f, 8r09:2f, 8r09:5f, 8r09:4f, 8r0a:5f, 8r0a:2f, 8r0a:4f, 8r0b:2f, 8r0b:4f, 8r0b:5f, 8rc0:m, 8rm5:2f, 8rm5:5f, 8rm5:4f, 8ro2:f, 6v4x:F, 7vpx:m, 7w59:f, 7w59:m, 7w5a:f, 7w5a:m, 7w5b:f, 7w5b:m, 4wzj:F, 4wzj:M, 4wzj:T, 4wzj:FF, 4wzj:TT, 4wzj:FFF, 4wzj:MMM, 4wzj:TTT, 4wzj:FFFF, 4wzj:MMMM, 4wzj:TTTT, 5xjc:f, 5xjc:m, 8y6o:f, 8y6o:m, 8y6o:t, 8y7e:m, 5yzg:f, 5yzg:m, 5z56:m, 5z57:m, 5z58:m
34 4wzj:KK 104 34 0.1122 0.1058 0.3235 1.2 7abg:h, 7abi:h, 6ahd:c, 7b0y:e, 8c6j:m, 8c6j:a, 7evo:a, 9fmd:k, 9fmd:d, 8h6e:5c, 8h6e:4c, 8h6j:5c, 8h6j:4c, 8h6k:5c, 8h6l:5c, 8hk1:a, 8i0p:c, 8i0p:h, 8i0r:c, 8i0r:h, 8i0s:c, 8i0s:h, 8i0t:h, 8i0u:c, 8i0u:h, 8i0v:c, 8i0v:h, 8i0w:c, 6icz:d, 6id0:d, 6id1:d, 5mqf:h, 5mqf:a, 4pjo:D, 4pjo:d, 4pjo:r, 8q7q:c, 8q7v:c, 8q7w:c, 8q7x:c, 8q91:j, 6qdv:m, 6qdv:j, 8qo9:22, 8qo9:52, 8qo9:42, 6qw6:42, 6qw6:52, 6qx9:12, 6qx9:52, 6qx9:22, 6qx9:42, 8qxd:22, 8qxd:42, 8qxd:52, 8qzs:52, 8qzs:22, 8r08:12, 8r08:42, 8r08:22, 8r08:52, 8r09:22, 8r09:52, 8r09:42, 8r0a:52, 8r0a:42, 8r0a:22, 8r0b:22, 8r0b:42, 8r0b:52, 8rc0:j, 8rm5:22, 8rm5:52, 8rm5:42, 8ro2:d, 7vpx:a, 7vpx:i, 7w59:d, 7w5a:d, 7w5b:d, 4wzj:D, 4wzj:K, 4wzj:R, 4wzj:DD, 4wzj:RR, 4wzj:DDD, 4wzj:KKK, 4wzj:RRR, 4wzj:DDDD, 4wzj:KKKK, 4wzj:RRRR, 5xjc:d, 6y53:h, 6y5q:h, 8y6o:c, 8y6o:j, 5yzg:d, 5z56:d, 5z57:d, 5z58:d
35 6v4x:D 106 43 0.1429 0.1321 0.3256 1.7
36 2ysl:A 73 20 0.1020 0.1370 0.5000 3.7 2ysj:A
37 6ttr:B 195 46 0.1327 0.0667 0.2826 3.7 6ttr:A, 6tts:A, 6tts:B
38 8ro0:e 80 55 0.1633 0.2000 0.2909 3.8 8ro1:e
39 2nwb:A 379 41 0.1429 0.0369 0.3415 4.7
40 6qw6:64 73 31 0.1224 0.1644 0.3871 5.6 6qx9:64
41 3jb9:G 95 61 0.1429 0.1474 0.2295 5.6 3jb9:l
42 6ppn:C 75 61 0.1633 0.2133 0.2623 5.7 6ppn:K, 6ppp:C, 6ppp:K, 6ppq:C, 6ppv:C
43 3u9j:A 157 44 0.1327 0.0828 0.2955 6.7 3u9j:B, 3u9m:A, 3u9m:C, 3u9m:E, 3u9m:G, 3v5x:A, 3v5x:B, 3v5y:A, 3v5y:B, 3v5y:C, 3v5y:D, 3v5z:A, 3v5z:B
44 3fp2:A 483 35 0.1020 0.0207 0.2857 7.6 3fp4:A, 3lca:A
45 3ujk:A 298 55 0.1735 0.0570 0.3091 9.5 3nmv:B, 3ujl:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218