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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TISFITWNIDGLDGCNLPERARGVCSCLALYSPDVVFLQEVIPPYCAYLKKRAASYTIITGNEEGYFTAILLKKGRVKFK
SQEIIPFPNTKMMRNLLCVNVSLGGNEFCLMTSHLESTREHSAERIRQLKTVLGKMQEAPDSTTVIFAGDTNLRDQEVIK
CGGLPDNVFDAWEFLGKPKHCQYTWDTKANNNLRIPAAYKHRFDRIFFRAEEGHLIPQSLDLVGLEKLDCGRFPSDHWGL
LCTLNV

The query sequence (length=246) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4puq:A 256 246 1.0000 0.9609 1.0000 0.0 4gyz:A, 4gyz:B, 4gyz:C, 4gyz:D, 4gyz:I, 4gyz:E, 4gyz:G, 4gyz:H, 4gz0:B, 4gz0:I, 4gz0:A, 4gz0:G, 4gz0:E, 4gz0:K, 4gz1:B, 4gz1:A, 4gz2:A, 4gz2:B, 5ht2:B, 5ht2:A, 5ink:B, 5ink:A, 5inl:B, 5inl:A, 5inm:A, 5inm:B, 5inm:D, 5inm:E, 5inp:B, 5inp:A, 5inq:B, 5inq:A, 5j3z:A, 5j3z:B, 5j42:A, 5j42:B, 4puq:B, 5tvp:I, 5tvp:O, 5tvp:G, 5tvp:E, 5tvp:B, 5tvp:A, 5tvp:K, 5tvp:M, 5tvq:A
2 5ino:A 253 245 0.7846 0.7628 0.7878 8.83e-147 5ino:B, 5j3p:A, 5j3s:A
3 5j3p:B 229 244 0.7154 0.7686 0.7213 1.06e-125
4 4fpv:B 257 246 0.5894 0.5642 0.5894 3.10e-108 6ca4:A, 6ca4:B, 4f1h:A, 4f1h:B, 4fpv:A
5 6ca4:C 229 246 0.5528 0.5939 0.5528 3.90e-94
6 4fva:C 251 248 0.3780 0.3705 0.3750 1.22e-45 4fva:A, 4fva:B, 4fva:D
7 6nf0:A 298 244 0.2073 0.1711 0.2090 0.027 6bt2:A
8 9biw:B 528 33 0.0569 0.0265 0.4242 0.21 9biw:A
9 5dv4:A 344 146 0.1341 0.0959 0.2260 0.59 5dv2:A, 3ngn:A, 3ngo:A, 3ngq:A
10 6hxj:D 591 44 0.0610 0.0254 0.3409 0.84 6hxj:B, 6hxj:F, 6hxj:H, 6hxn:A, 6hxn:B, 6hxo:A, 6hxo:B, 6hxo:F, 6hxo:G, 6hxo:H, 6nzy:A, 6nzy:D, 6qcl:B, 6qcl:E, 6qcl:F, 6qcl:G, 6qcl:H
11 3rkr:A 221 84 0.0976 0.1086 0.2857 1.1 3rkr:B
12 8jzn:A 1489 47 0.0650 0.0107 0.3404 2.8
13 7w2t:A 773 59 0.0610 0.0194 0.2542 3.0 5bvu:A, 5bx2:A, 5bx3:A, 5bx4:A, 5bx5:A, 7dks:A, 7dkt:A, 7dku:A, 7dkv:A, 7dkw:A, 7dkw:B, 7dkx:A, 7dky:A, 8i5o:A, 8i5p:A, 8i5p:B, 8i5q:A, 8i5q:B, 8i5r:A, 8i5s:A, 8i5t:A, 8i5u:A, 8jbo:A, 8jbo:B, 5ncx:A, 5npf:A, 5o0s:A, 5ost:A, 8r06:A, 7w2s:A, 7w2t:B, 7w2v:A, 7w2w:A, 7w2x:A
14 5t96:B 330 43 0.0691 0.0515 0.3953 3.7 5t96:A, 5t96:C, 5t96:D, 5t96:E, 5t96:F
15 8d0b:B 362 113 0.1260 0.0856 0.2743 4.5 8d0k:B
16 2vpt:A 201 29 0.0447 0.0547 0.3793 6.3
17 4fdg:B 592 33 0.0447 0.0186 0.3333 8.1 8eaf:A, 8eaf:B, 8eaf:C, 8eaf:D, 8eaf:E, 8eaf:F, 8eag:B, 8eag:C, 8eag:D, 8eag:E, 8eag:F, 8eag:A, 8eah:A, 8eah:B, 8eah:C, 8eah:D, 8eah:E, 8eah:F, 8eai:B, 8eai:C, 8eai:D, 8eai:E, 8eai:F, 8eai:A, 8eaj:A, 8eaj:B, 8eaj:C, 8eaj:D, 8eaj:E, 8eaj:F, 8eak:B, 8eak:C, 8eak:D, 8eak:E, 8eak:A, 8eak:F, 8eal:A, 8eal:B, 8eal:C, 8eal:D, 8eal:E, 8eal:F, 8eam:B, 8eam:C, 8eam:D, 8eam:E, 8eam:A, 8eam:F, 4fdg:A, 4fdg:C, 4fdg:D, 4fdg:E, 6mii:A, 6mii:B, 6mii:C, 6mii:D, 6mii:E, 6mii:F, 2vl6:A, 2vl6:B, 2vl6:C, 6wnz:B, 6wnz:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218