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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TIRVGINGFGRIGRNFFRAVLERSDDLEVVAVNDSKDNKTLSTLLKFDSIMGRLGQEVEYDDDSITVGGKRIAVYAERDP
KNLDWAAHNVDIVIESTGFFTDANAAKAHIEAGAKKVIISAPASNEDATFVYGVNHESYDPENHNVISGASCTTNCLAPM
AKVLNDKFGIENGLMTTVHAYTGDQRLHDAPHRDLRRARAAAVNIVPTSTGAAKAVALVLPELKGKLDGYALRVPVITGS
ATDLTFNTKSEVTVESINAAIKEAAVGEFGETLAYSEEPLVSTDIVHDSHGSIFDAGLTKVSGNTVKVVSWYDNEWGYTC
QLLRLTELVASKLL

The query sequence (length=334) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8hrq:B 336 334 1.0000 0.9940 1.0000 0.0 8hro:A, 8hro:B, 8hrp:A, 8hrp:B, 8hrp:C, 8hrp:D, 8hrp:E, 8hrp:F, 8hrp:G, 8hrp:H, 8hrq:A, 8hrr:A, 8hrr:B, 8hrs:A, 8hrs:B, 8hrs:C, 8hrs:D, 8hrt:A, 8hrt:B, 8hrt:C, 8hrt:D
2 8br4:A 339 339 0.6287 0.6195 0.6195 3.71e-146 8br4:B, 8br4:C, 8br4:D, 8br4:E, 8br4:F, 8br4:G, 8br4:H, 8br4:I, 8br4:J, 8br4:K, 8br4:L, 8br4:M, 8br4:N, 8br4:O, 8br4:P
3 3cmc:O 334 334 0.6168 0.6168 0.6168 9.54e-139 3cmc:P, 3cmc:Q, 3cmc:R, 1dbv:O, 1dbv:P, 1dbv:Q, 1dbv:R, 2dbv:O, 2dbv:P, 2dbv:Q, 2dbv:R, 3dbv:O, 3dbv:P, 3dbv:Q, 3dbv:R, 4dbv:O, 4dbv:P, 4dbv:Q, 4dbv:R, 1gd1:O, 1gd1:P, 1gd1:Q, 1gd1:R, 1npt:O, 1npt:P, 1npt:Q, 1npt:R, 1nq5:O, 1nq5:Q, 1nq5:A, 1nq5:C, 1nqa:O, 1nqa:P, 1nqa:Q, 1nqa:R, 1nqo:O, 1nqo:Q, 1nqo:A, 1nqo:C
4 1cer:O 331 331 0.6048 0.6103 0.6103 6.62e-135 1cer:P, 1cer:Q, 1cer:R, 1cer:A, 1cer:B, 1cer:C, 1cer:D, 2g82:O, 2g82:P, 2g82:Q, 2g82:R, 2g82:A, 2g82:B, 2g82:C, 2g82:D, 1vc2:A
5 2ep7:B 339 339 0.5808 0.5723 0.5723 7.44e-133 2ep7:A
6 1hdg:O 332 329 0.5539 0.5572 0.5623 3.38e-128 1hdg:Q
7 3doc:A 335 323 0.5449 0.5433 0.5635 1.91e-123 3doc:B, 3doc:C, 3doc:D
8 3gnq:C 335 326 0.5539 0.5522 0.5675 2.11e-123 3gnq:B, 3gnq:D, 3gnq:E, 3gnq:F, 3gnq:G, 3gnq:H
9 5utm:A 345 336 0.5629 0.5449 0.5595 3.25e-121 5jy6:A, 5jy6:B, 5jy6:C, 5jy6:D, 5jya:A, 5jya:B, 5jya:C, 5jya:D, 5jye:A, 5jye:C, 4qx6:A, 4qx6:B, 4qx6:C, 4qx6:D, 5utl:A, 5utl:B, 5utl:C, 5utl:D, 5utm:B, 5utm:C, 5utm:D, 5v8x:A, 5v8x:B, 5v8x:C, 5v8x:D, 5y37:A, 5y37:B
10 5m6d:A 346 335 0.5479 0.5289 0.5463 2.12e-119 6fzh:A, 6fzh:B, 6ite:P, 6ite:Q, 6ite:R, 6ite:O
11 5vmt:B 334 339 0.5479 0.5479 0.5398 1.28e-118 5vmt:A, 5vmt:C, 5vmt:D, 5vmt:F, 5vmt:G, 5vmt:H
12 1obf:O 335 329 0.5389 0.5373 0.5471 1.61e-117 1obf:P
13 3lvf:P 338 330 0.5419 0.5355 0.5485 6.39e-117 3hq4:R, 3hq4:O, 3hq4:P, 3hq4:Q, 3k73:Q, 3k73:O, 3k73:P, 3k73:R, 3k9q:Q, 3k9q:O, 3k9q:P, 3k9q:R, 3ksd:Q, 3ksd:R, 3ksd:O, 3ksd:P, 3ksz:O, 3ksz:P, 3ksz:R, 3ksz:Q, 3kv3:O, 3kv3:Q, 3kv3:R, 3kv3:P, 3l4s:Q, 3l4s:P, 3l4s:O, 3l4s:R, 3l6o:Q, 3l6o:P, 3l6o:R, 3l6o:O, 3lc1:P, 3lc1:R, 3lc1:O, 3lc1:Q, 3lc2:O, 3lc2:Q, 3lc2:R, 3lc2:P, 3lvf:R, 3lvf:O, 3lvf:Q, 5t73:A, 5t73:B, 5t73:C, 5t73:D, 3vaz:P, 3vaz:R, 3vaz:O, 3vaz:Q, 3vaz:B, 3vaz:A
14 3hja:A 334 334 0.5389 0.5389 0.5389 8.28e-117 3hja:B, 3hja:C, 3hja:D
15 6ghr:B 342 334 0.5359 0.5234 0.5359 3.05e-116 4boy:A, 4boy:B, 6gfo:A, 6gfo:B, 6gfo:C, 6gfo:D, 6gfp:A, 6gfp:B, 6gfq:B, 6gfq:A, 6gfr:A, 6gfr:B, 6gg7:B, 6gg7:A, 6ghl:A, 6ghl:D, 6ghl:B, 6ghl:C, 6ghr:D, 6ghr:A, 6ghr:C, 6gve:D, 6gve:A, 6gve:E, 6gve:F, 6gve:I, 6gve:K, 6gve:N, 6gve:O, 3zcx:A, 3zcx:B, 3zdf:B, 3zdf:A
16 6fzi:B 332 337 0.5569 0.5602 0.5519 5.57e-116 6fzi:A, 6fzi:C, 6fzi:D
17 3b1j:A 338 335 0.5479 0.5414 0.5463 8.38e-116 3b1j:B, 3b1k:A, 3b1k:H, 3b1k:B, 3b1k:G, 3b20:A, 3b20:B, 3b20:O, 3b20:P, 3b20:Q, 3b20:R, 2d2i:A, 2d2i:B, 2d2i:O, 2d2i:P, 2d2i:Q, 2d2i:R, 2duu:A, 2duu:B, 2duu:O, 2duu:P, 2duu:Q, 2duu:R
18 5ld5:C 342 334 0.5599 0.5468 0.5599 4.40e-115 5ld5:A, 5ld5:B, 5ld5:D
19 3l0d:A 332 324 0.5120 0.5151 0.5278 6.07e-115 3l0d:B
20 7jwk:C 333 335 0.5120 0.5135 0.5104 3.79e-114 7jwk:A, 7jwk:B, 7jwk:D
21 1nbo:O 337 334 0.5359 0.5312 0.5359 2.34e-112 1jn0:O, 1jn0:A, 1jn0:B, 1nbo:A, 1nbo:B, 2pkq:P, 2pkq:R, 2pkq:S, 2pkr:O, 2pkr:R, 2pkr:P, 2pkr:Q, 2pkr:A, 2pkr:B, 2pkr:C, 2pkr:D, 2pkr:H, 2pkr:I, 2pkr:L, 2pkr:M, 7q53:P, 7q53:R, 7q54:R, 7q54:P, 7q54:B, 7q54:D, 7q55:P, 7q55:R, 7q55:B, 7q55:D, 7q55:F, 7q55:H, 7q55:J, 7q55:L, 7q56:J, 7q56:L, 7q56:B, 7q56:D, 7q56:R, 7q56:P, 7q56:H, 7q56:F, 7q57:P, 7q57:R, 7q57:B, 7q57:D, 7q57:H, 7q57:F, 7q57:J, 7q57:L, 7q57:N, 7q57:T, 1rm3:O, 1rm3:A, 1rm3:B, 1rm4:O, 1rm4:A, 1rm4:B, 1rm5:O, 1rm5:A, 1rm5:B
22 3pym:A 332 332 0.5210 0.5241 0.5241 6.02e-112 3pym:B
23 7c5o:O 338 333 0.5150 0.5089 0.5165 2.31e-111 7c5f:O, 7c5f:P, 7c5f:Q, 7c5f:R, 7c5g:O, 7c5g:P, 7c5g:Q, 7c5g:R, 7c5h:O, 7c5h:P, 7c5h:Q, 7c5h:R, 7c5i:O, 7c5i:P, 7c5i:Q, 7c5i:R, 7c5j:O, 7c5j:P, 7c5j:Q, 7c5j:R, 7c5k:O, 7c5k:P, 7c5k:Q, 7c5k:R, 7c5l:O, 7c5l:P, 7c5l:Q, 7c5l:R, 7c5m:O, 7c5m:P, 7c5m:Q, 7c5m:R, 7c5n:O, 7c5n:P, 7c5n:Q, 7c5n:R, 7c5o:P, 7c5o:Q, 7c5o:R, 7c5p:O, 7c5p:P, 7c5p:Q, 7c5p:R, 7c5q:O, 7c5q:P, 7c5q:Q, 7c5q:R, 7c5r:O, 7c5r:P, 7c5r:Q, 7c5r:R, 7c7k:O, 7c7k:P, 7c7k:Q, 7c7k:R
24 8de5:A 338 333 0.5150 0.5089 0.5165 1.01e-109
25 7q54:C 368 336 0.5539 0.5027 0.5506 3.34e-107 2pkq:O, 2pkq:Q, 2pkq:T, 7q53:O, 7q53:Q, 7q54:Q, 7q54:O, 7q54:A, 7q55:O, 7q55:Q, 7q55:A, 7q55:C, 7q55:E, 7q55:G, 7q55:I, 7q55:K, 7q56:K, 7q56:E, 7q56:I, 7q56:A, 7q56:G, 7q56:C, 7q56:Q, 7q56:O, 7q57:O, 7q57:Q, 7q57:A, 7q57:C, 7q57:G, 7q57:E, 7q57:I, 7q57:K, 7q57:M, 7q57:S
26 4p8r:A 331 327 0.5030 0.5076 0.5138 4.89e-106 4p8r:B, 4p8r:C, 4p8r:D
27 7zq3:R 348 337 0.5569 0.5345 0.5519 7.39e-106 7zq3:O, 7zq4:O, 7zq4:R, 7zqk:O, 7zqk:R
28 4mvj:B 332 328 0.5060 0.5090 0.5152 2.20e-105 1dc4:A, 1dc4:B, 1dc6:A, 1dc6:B, 1gad:O, 1gad:P, 1gae:O, 1gae:P, 6io6:A, 4mvj:A, 4mvj:C, 4mvj:D, 4mvj:E, 4mvj:F, 4mvj:G, 4mvj:I, 4mvj:J, 4mvj:K, 4mvj:L, 4mvj:M, 4mvj:O, 4mvj:P, 6utm:A, 6utm:B, 6utn:A, 6utn:B, 6uto:A, 6uto:B, 2vyn:A, 2vyn:B, 2vyn:C, 2vyv:A, 2vyv:B, 2vyv:C, 5za0:A
29 1ywg:O 337 329 0.4910 0.4866 0.4985 5.03e-105 2b4r:O, 2b4r:P, 2b4r:Q, 2b4r:R, 2b4t:O, 2b4t:P, 2b4t:Q, 2b4t:R, 1ywg:P, 1ywg:Q, 1ywg:R
30 7xzg:A 334 333 0.5090 0.5090 0.5105 8.95e-105 7xzg:B, 7xzg:C, 7xzg:D
31 8oha:B 336 333 0.4910 0.4881 0.4925 8.52e-104 8oha:A, 8oha:C, 8oha:D, 8oha:E, 8oha:F, 8oha:G, 8oha:H
32 6nlx:C 335 328 0.4910 0.4896 0.5000 1.04e-103 6nlx:B, 6nlx:D, 5ur0:A, 5ur0:B, 5ur0:C, 5ur0:D
33 7www:A 336 333 0.4880 0.4851 0.4895 2.12e-103
34 8hmn:D 340 334 0.4850 0.4765 0.4850 1.47e-102 8hmn:A, 8hmn:B, 8hmn:C, 6iqm:A, 6iqm:B, 6iqm:C, 6iqm:D
35 7bew:A 330 330 0.4611 0.4667 0.4667 3.23e-102 7bex:A
36 6ok4:A 334 330 0.4760 0.4760 0.4818 3.56e-102 6ok4:B, 6ok4:C, 6ok4:D, 6wyc:A, 6wyc:B, 6wyc:C, 6wyc:D, 6x2e:A, 6x2e:C, 6x2e:D
37 6m5x:O 334 333 0.4850 0.4850 0.4865 4.40e-101 6m5x:R, 6m5x:P, 6m5x:Q
38 3k2b:A 337 333 0.5240 0.5193 0.5255 1.14e-99 3k2b:B, 3k2b:C, 3k2b:D, 3k2b:E, 3k2b:F, 3k2b:G, 3k2b:H, 3k2b:O, 3k2b:Q, 6kez:A, 6kez:B, 6kez:C, 6kez:D, 6kez:E, 6kez:F, 6kez:G, 6kez:H, 3qv1:A, 3qv1:D, 3qv1:B, 3qv1:C, 3qv1:F, 3qv1:E, 3rvd:A, 3rvd:D, 3rvd:B, 3rvd:C, 3rvd:O, 3rvd:Q, 3rvd:F, 3rvd:G, 3rvd:E, 3rvd:H
39 4lsm:A 331 334 0.4701 0.4743 0.4701 1.40e-99 4lsm:B
40 6qun:O 334 329 0.4820 0.4820 0.4894 2.87e-99 6qun:R, 6quq:O, 6quq:R, 4z0h:O, 4z0h:R
41 6px2:A 332 334 0.4820 0.4849 0.4820 4.29e-99 6px2:B, 6px2:C, 6px2:D, 6px2:E, 6px2:F, 6px2:G, 6px2:H
42 4k9d:A 338 337 0.4850 0.4793 0.4807 7.80e-98 4k9d:B, 4k9d:C, 4k9d:D, 4k9d:E, 4k9d:F, 4k9d:G, 4k9d:H
43 3h9e:P 337 334 0.4701 0.4659 0.4701 2.24e-97 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
44 3cif:A 338 339 0.4701 0.4645 0.4631 4.25e-97 3cif:B, 3cif:C, 3cif:D, 3cps:A, 3cps:B, 8pvf:A, 1vsv:A, 1vsv:B, 1vsv:C, 1vsv:D
45 3dmt:A 359 351 0.4701 0.4373 0.4473 8.02e-97 3dmt:B, 3dmt:C, 3dmt:D, 3ids:D, 1k3t:C, 1ml3:B, 1ml3:C, 1ml3:D, 1qxs:C, 1qxs:D, 1qxs:A, 1qxs:B, 2x0n:A, 2x0n:B, 2x0n:O, 2x0n:P, 2x0n:Q, 2x0n:R
46 1a7k:A 358 351 0.4820 0.4497 0.4587 1.56e-95 1a7k:B, 1a7k:C, 1a7k:D, 1gyp:A, 1gyp:B, 1gyp:C, 1gyp:D, 1gyq:A, 1gyq:B, 1gyq:C, 1gyq:D, 1i32:A, 1i32:B, 1i32:C, 1i32:D, 1i32:E, 1i32:F, 1i33:A, 1i33:B, 1i33:C, 1i33:D, 1i33:E, 1i33:F
47 9iil:A 341 336 0.4371 0.4282 0.4345 1.16e-94 9iil:B, 9iil:C, 9iil:D, 9iim:A, 9iim:C, 9iim:B, 9iim:D, 9ij6:A, 9ij6:C, 9ij6:B, 9ij6:D, 8zn1:A, 8zn1:C, 8zn1:B, 8zn1:D, 8zn4:A, 8zn4:B, 8zn4:C, 8zn4:D, 8zoz:A, 8zoz:C, 8zoz:B, 8zoz:D
48 3e5r:O 336 334 0.4671 0.4643 0.4671 1.20e-94 3e5r:A, 3e5r:B, 3e5r:C, 3v1y:O, 3v1y:A, 3v1y:B, 3v1y:C
49 2vyn:D 334 334 0.4551 0.4551 0.4551 2.52e-93 2vyv:D
50 1dss:G 333 328 0.4701 0.4715 0.4787 3.13e-93 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
51 3sth:C 340 335 0.4701 0.4618 0.4687 3.91e-93 3sth:A, 3sth:B, 3sth:D
52 2i5p:O 309 331 0.4431 0.4790 0.4471 7.01e-93 2i5p:P
53 5vmt:E 293 331 0.4880 0.5563 0.4924 1.07e-92
54 6m61:O 336 334 0.4491 0.4464 0.4491 6.39e-92 6ade:A, 5ddi:P, 5ddi:R, 5ddi:S, 6iq6:A, 6iq6:B, 6iq6:C, 6iq6:D, 6iq6:E, 1j0x:P, 1j0x:R, 6lgj:A, 6lgj:B, 6lgj:C, 6lgj:D, 6lgk:A, 6lgk:B, 6lgk:C, 6lgm:A, 6lgm:B, 6lgm:C, 6m61:Q, 6m61:P, 4o59:O, 4o59:P, 4o59:R, 4o59:Q, 4o63:P, 4o63:Q, 4o63:R, 8p5f:AAA, 8p5f:DDD, 8p5f:EEE, 8p5f:GGG, 5tso:P, 5tso:R, 5tso:S, 7u5m:A, 7u5m:B, 7u5m:C, 7u5m:D, 1u8f:P, 1u8f:Q, 1u8f:R, 4wnc:O, 4wnc:E, 4wnc:A, 4wnc:B, 4wnc:C, 4wnc:D, 4wni:O, 4wni:A, 4wni:B, 1znq:O, 1znq:P, 1znq:R, 1znq:Q
55 3gpd:R 334 334 0.4491 0.4491 0.4491 4.05e-90 3gpd:G
56 2xf8:M 327 335 0.4192 0.4281 0.4179 6.97e-86 2xf8:A, 2xf8:C, 2xf8:E, 2xf8:G, 2xf8:I, 2xf8:K, 2xf8:O
57 8jb1:A 468 337 0.3593 0.2564 0.3561 1.80e-62 8jb1:B
58 1cf2:P 336 173 0.1347 0.1339 0.2601 0.007 1cf2:R, 1cf2:O, 1cf2:Q
59 3wyc:A 327 41 0.0509 0.0520 0.4146 0.022 5gz3:A, 5gz3:B, 5gz6:A, 3wyc:B
60 2czc:A 334 167 0.1108 0.1108 0.2216 0.23 2czc:B, 2czc:C, 2czc:D
61 1ys4:A 348 38 0.0389 0.0374 0.3421 0.42 1ys4:B
62 3wgy:B 324 36 0.0419 0.0432 0.3889 0.78 3wgq:A, 3wgz:B
63 2hun:A 329 26 0.0359 0.0365 0.4615 0.91 2hun:B
64 7zbo:A 348 37 0.0419 0.0402 0.3784 2.9 7r09:A, 7zbo:B, 7zbo:C, 7zbo:D
65 1srd:A 154 44 0.0479 0.1039 0.3636 5.1 1srd:B, 1srd:C, 1srd:D
66 3hsk:A 358 137 0.1018 0.0950 0.2482 5.3
67 3ec7:A 336 47 0.0479 0.0476 0.3404 5.4 3ec7:B, 3ec7:C, 3ec7:D, 3ec7:E, 3ec7:F, 3ec7:G, 3ec7:H
68 3pyl:C 361 133 0.0958 0.0886 0.2406 6.5 2gz1:A, 2gz1:B, 2gz2:A, 2gz2:B, 2gz3:A, 2gz3:B, 2gz3:C, 2gz3:D, 3pwk:A, 3pwk:B, 3pws:A, 3pws:B, 3pyl:A, 3pyl:B, 3pyx:A, 3pyx:B, 3pzb:A, 3pzb:B, 3q11:A, 3q11:B, 3q1l:A, 3q1l:B, 3q1l:C, 3q1l:D, 4r3n:A, 4r3n:B, 4r3w:A, 4r3w:B, 4r41:A, 4r41:B, 4r4j:A, 4r4j:B, 4r51:A, 4r51:B, 4r54:A, 4r54:B, 4r5h:A, 4r5h:B
69 6j3h:A 264 46 0.0449 0.0568 0.3261 7.6 6j3h:B, 6j3h:C, 6j3h:D
70 8uw3:A 1265 73 0.0569 0.0150 0.2603 8.0 7n8s:A, 7n94:A, 7n94:B, 8sp5:A, 8sp5:B, 8sp7:A, 8sxt:A, 8sxu:A, 1vyb:B
71 8ea3:Y 304 56 0.0599 0.0658 0.3571 8.6 8aa5:CP1, 8aa5:DP1, 8ea3:Z, 8ea4:Z, 8ea4:Y, 8rdu:U, 8rdu:T, 8rkv:U, 8rkv:T, 7svw:A, 7svw:C
72 3tz6:A 342 133 0.0958 0.0936 0.2406 8.8 3vos:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218