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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TIRVAINGYGRIGRNTLRAFYENGKKHDLEIVAINDLGDAKTNAHLTQYDTAHGKFPGEVSVDGDYLVVNGDRIRVLANR
NPAELPWGELGVDVVMECTGFFTSKEKASAHLKGGAKKVIISAPGGKDVDATIVYGVNHDVLKAEHTVISNASCTTNCLA
PLVKPLNDKIGLETGLMTTIHAYTNDQVLTDVYHEDLRRARSATHSQIPTKTGAAAAVGLVLPELNGKLDGYAIRVPTIN
VSIVDLSFIAKRDTTAAEVNAIMKEASEGALKGILGYNEAPLVSIDFNHNPASSTFDATLTKVSGRLVKVSSWYDNEWGF
SNRMLDTAIALANA

The query sequence (length=334) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3gnq:C 335 334 1.0000 0.9970 1.0000 0.0 3gnq:B, 3gnq:D, 3gnq:E, 3gnq:F, 3gnq:G, 3gnq:H
2 1obf:O 335 334 0.8293 0.8269 0.8293 0.0 1obf:P
3 3doc:A 335 331 0.6257 0.6239 0.6314 1.16e-147 3doc:B, 3doc:C, 3doc:D
4 3l0d:A 332 333 0.5958 0.5994 0.5976 1.13e-144 3l0d:B
5 1hdg:O 332 326 0.5689 0.5723 0.5828 1.54e-133 1hdg:Q
6 3cmc:O 334 334 0.5808 0.5808 0.5808 3.03e-130 3cmc:P, 3cmc:Q, 3cmc:R, 1dbv:O, 1dbv:P, 1dbv:Q, 1dbv:R, 2dbv:O, 2dbv:P, 2dbv:Q, 2dbv:R, 3dbv:O, 3dbv:P, 3dbv:Q, 3dbv:R, 4dbv:O, 4dbv:P, 4dbv:Q, 4dbv:R, 1gd1:O, 1gd1:P, 1gd1:Q, 1gd1:R, 1npt:O, 1npt:P, 1npt:Q, 1npt:R, 1nq5:O, 1nq5:Q, 1nq5:A, 1nq5:C, 1nqa:O, 1nqa:P, 1nqa:Q, 1nqa:R, 1nqo:O, 1nqo:Q, 1nqo:A, 1nqo:C
7 2xf8:M 327 333 0.5240 0.5352 0.5255 6.31e-129 2xf8:A, 2xf8:C, 2xf8:E, 2xf8:G, 2xf8:I, 2xf8:K, 2xf8:O
8 8br4:A 339 330 0.5479 0.5398 0.5545 3.13e-120 8br4:B, 8br4:C, 8br4:D, 8br4:E, 8br4:F, 8br4:G, 8br4:H, 8br4:I, 8br4:J, 8br4:K, 8br4:L, 8br4:M, 8br4:N, 8br4:O, 8br4:P
9 6fzi:B 332 336 0.5719 0.5753 0.5685 3.24e-119 6fzi:A, 6fzi:C, 6fzi:D
10 2ep7:B 339 340 0.5389 0.5310 0.5294 6.28e-119 2ep7:A
11 8hrq:B 336 326 0.5539 0.5506 0.5675 3.29e-118 8hro:A, 8hro:B, 8hrp:A, 8hrp:B, 8hrp:C, 8hrp:D, 8hrp:E, 8hrp:F, 8hrp:G, 8hrp:H, 8hrq:A, 8hrr:A, 8hrr:B, 8hrs:A, 8hrs:B, 8hrs:C, 8hrs:D, 8hrt:A, 8hrt:B, 8hrt:C, 8hrt:D
12 6ghr:B 342 333 0.5269 0.5146 0.5285 7.46e-117 4boy:A, 4boy:B, 6gfo:A, 6gfo:B, 6gfo:C, 6gfo:D, 6gfp:A, 6gfp:B, 6gfq:B, 6gfq:A, 6gfr:A, 6gfr:B, 6gg7:B, 6gg7:A, 6ghl:A, 6ghl:D, 6ghl:B, 6ghl:C, 6ghr:D, 6ghr:A, 6ghr:C, 6gve:D, 6gve:A, 6gve:E, 6gve:F, 6gve:I, 6gve:K, 6gve:N, 6gve:O, 3zcx:A, 3zcx:B, 3zdf:B, 3zdf:A
13 1cer:O 331 326 0.5359 0.5408 0.5491 1.64e-116 1cer:P, 1cer:Q, 1cer:R, 1cer:A, 1cer:B, 1cer:C, 1cer:D, 2g82:O, 2g82:P, 2g82:Q, 2g82:R, 2g82:A, 2g82:B, 2g82:C, 2g82:D, 1vc2:A
14 5vmt:B 334 333 0.5269 0.5269 0.5285 4.42e-114 5vmt:A, 5vmt:C, 5vmt:D, 5vmt:F, 5vmt:G, 5vmt:H
15 9iil:A 341 332 0.4850 0.4751 0.4880 1.35e-113 9iil:B, 9iil:C, 9iil:D, 9iim:A, 9iim:C, 9iim:B, 9iim:D, 9ij6:A, 9ij6:C, 9ij6:B, 9ij6:D, 8zn1:A, 8zn1:C, 8zn1:B, 8zn1:D, 8zn4:A, 8zn4:B, 8zn4:C, 8zn4:D, 8zoz:A, 8zoz:C, 8zoz:B, 8zoz:D
16 1nbo:O 337 334 0.5240 0.5193 0.5240 9.51e-111 1jn0:O, 1jn0:A, 1jn0:B, 1nbo:A, 1nbo:B, 2pkq:P, 2pkq:R, 2pkq:S, 2pkr:O, 2pkr:R, 2pkr:P, 2pkr:Q, 2pkr:A, 2pkr:B, 2pkr:C, 2pkr:D, 2pkr:H, 2pkr:I, 2pkr:L, 2pkr:M, 7q53:P, 7q53:R, 7q54:R, 7q54:P, 7q54:B, 7q54:D, 7q55:P, 7q55:R, 7q55:B, 7q55:D, 7q55:F, 7q55:H, 7q55:J, 7q55:L, 7q56:J, 7q56:L, 7q56:B, 7q56:D, 7q56:R, 7q56:P, 7q56:H, 7q56:F, 7q57:P, 7q57:R, 7q57:B, 7q57:D, 7q57:H, 7q57:F, 7q57:J, 7q57:L, 7q57:N, 7q57:T, 1rm3:O, 1rm3:A, 1rm3:B, 1rm4:O, 1rm4:A, 1rm4:B, 1rm5:O, 1rm5:A, 1rm5:B
17 4p8r:A 331 327 0.5090 0.5136 0.5199 6.44e-107 4p8r:B, 4p8r:C, 4p8r:D
18 3b1j:A 338 331 0.5150 0.5089 0.5196 1.17e-106 3b1j:B, 3b1k:A, 3b1k:H, 3b1k:B, 3b1k:G, 3b20:A, 3b20:B, 3b20:O, 3b20:P, 3b20:Q, 3b20:R, 2d2i:A, 2d2i:B, 2d2i:O, 2d2i:P, 2d2i:Q, 2d2i:R, 2duu:A, 2duu:B, 2duu:O, 2duu:P, 2duu:Q, 2duu:R
19 4mvj:B 332 328 0.5060 0.5090 0.5152 1.72e-106 1dc4:A, 1dc4:B, 1dc6:A, 1dc6:B, 1gad:O, 1gad:P, 1gae:O, 1gae:P, 6io6:A, 4mvj:A, 4mvj:C, 4mvj:D, 4mvj:E, 4mvj:F, 4mvj:G, 4mvj:I, 4mvj:J, 4mvj:K, 4mvj:L, 4mvj:M, 4mvj:O, 4mvj:P, 6utm:A, 6utm:B, 6utn:A, 6utn:B, 6uto:A, 6uto:B, 2vyn:A, 2vyn:B, 2vyn:C, 2vyv:A, 2vyv:B, 2vyv:C, 5za0:A
20 3hja:A 334 338 0.5120 0.5120 0.5059 2.23e-106 3hja:B, 3hja:C, 3hja:D
21 8de5:A 338 331 0.5120 0.5059 0.5166 8.90e-106
22 6m5x:O 334 328 0.5090 0.5090 0.5183 8.38e-105 6m5x:R, 6m5x:P, 6m5x:Q
23 3k2b:A 337 334 0.5269 0.5223 0.5269 4.78e-104 3k2b:B, 3k2b:C, 3k2b:D, 3k2b:E, 3k2b:F, 3k2b:G, 3k2b:H, 3k2b:O, 3k2b:Q, 6kez:A, 6kez:B, 6kez:C, 6kez:D, 6kez:E, 6kez:F, 6kez:G, 6kez:H, 3qv1:A, 3qv1:D, 3qv1:B, 3qv1:C, 3qv1:F, 3qv1:E, 3rvd:A, 3rvd:D, 3rvd:B, 3rvd:C, 3rvd:O, 3rvd:Q, 3rvd:F, 3rvd:G, 3rvd:E, 3rvd:H
24 5m6d:A 346 332 0.5060 0.4884 0.5090 1.13e-103 6fzh:A, 6fzh:B, 6ite:P, 6ite:Q, 6ite:R, 6ite:O
25 1ywg:O 337 336 0.4940 0.4896 0.4911 3.25e-103 2b4r:O, 2b4r:P, 2b4r:Q, 2b4r:R, 2b4t:O, 2b4t:P, 2b4t:Q, 2b4t:R, 1ywg:P, 1ywg:Q, 1ywg:R
26 3dmt:A 359 353 0.5210 0.4847 0.4929 1.07e-102 3dmt:B, 3dmt:C, 3dmt:D, 3ids:D, 1k3t:C, 1ml3:B, 1ml3:C, 1ml3:D, 1qxs:C, 1qxs:D, 1qxs:A, 1qxs:B, 2x0n:A, 2x0n:B, 2x0n:O, 2x0n:P, 2x0n:Q, 2x0n:R
27 7xzg:A 334 337 0.4970 0.4970 0.4926 1.43e-101 7xzg:B, 7xzg:C, 7xzg:D
28 5utm:A 345 333 0.4970 0.4812 0.4985 1.84e-101 5jy6:A, 5jy6:B, 5jy6:C, 5jy6:D, 5jya:A, 5jya:B, 5jya:C, 5jya:D, 5jye:A, 5jye:C, 4qx6:A, 4qx6:B, 4qx6:C, 4qx6:D, 5utl:A, 5utl:B, 5utl:C, 5utl:D, 5utm:B, 5utm:C, 5utm:D, 5v8x:A, 5v8x:B, 5v8x:C, 5v8x:D, 5y37:A, 5y37:B
29 7zq3:R 348 331 0.5180 0.4971 0.5227 1.98e-101 7zq3:O, 7zq4:O, 7zq4:R, 7zqk:O, 7zqk:R
30 6nlx:C 335 333 0.4850 0.4836 0.4865 2.61e-101 6nlx:B, 6nlx:D, 5ur0:A, 5ur0:B, 5ur0:C, 5ur0:D
31 6m61:O 336 336 0.4940 0.4911 0.4911 3.14e-101 6ade:A, 5ddi:P, 5ddi:R, 5ddi:S, 6iq6:A, 6iq6:B, 6iq6:C, 6iq6:D, 6iq6:E, 1j0x:P, 1j0x:R, 6lgj:A, 6lgj:B, 6lgj:C, 6lgj:D, 6lgk:A, 6lgk:B, 6lgk:C, 6lgm:A, 6lgm:B, 6lgm:C, 6m61:Q, 6m61:P, 4o59:O, 4o59:P, 4o59:R, 4o59:Q, 4o63:P, 4o63:Q, 4o63:R, 8p5f:AAA, 8p5f:DDD, 8p5f:EEE, 8p5f:GGG, 5tso:P, 5tso:R, 5tso:S, 7u5m:A, 7u5m:B, 7u5m:C, 7u5m:D, 1u8f:P, 1u8f:Q, 1u8f:R, 4wnc:O, 4wnc:E, 4wnc:A, 4wnc:B, 4wnc:C, 4wnc:D, 4wni:O, 4wni:A, 4wni:B, 1znq:O, 1znq:P, 1znq:R, 1znq:Q
32 7q54:C 368 341 0.5180 0.4701 0.5073 5.91e-101 2pkq:O, 2pkq:Q, 2pkq:T, 7q53:O, 7q53:Q, 7q54:Q, 7q54:O, 7q54:A, 7q55:O, 7q55:Q, 7q55:A, 7q55:C, 7q55:E, 7q55:G, 7q55:I, 7q55:K, 7q56:K, 7q56:E, 7q56:I, 7q56:A, 7q56:G, 7q56:C, 7q56:Q, 7q56:O, 7q57:O, 7q57:Q, 7q57:A, 7q57:C, 7q57:G, 7q57:E, 7q57:I, 7q57:K, 7q57:M, 7q57:S
33 8oha:B 336 328 0.4940 0.4911 0.5030 7.19e-100 8oha:A, 8oha:C, 8oha:D, 8oha:E, 8oha:F, 8oha:G, 8oha:H
34 7bew:A 330 332 0.4641 0.4697 0.4669 3.10e-99 7bex:A
35 4lsm:A 331 328 0.4790 0.4834 0.4878 7.63e-99 4lsm:B
36 3lvf:P 338 339 0.4940 0.4882 0.4867 7.70e-99 3hq4:R, 3hq4:O, 3hq4:P, 3hq4:Q, 3k73:Q, 3k73:O, 3k73:P, 3k73:R, 3k9q:Q, 3k9q:O, 3k9q:P, 3k9q:R, 3ksd:Q, 3ksd:R, 3ksd:O, 3ksd:P, 3ksz:O, 3ksz:P, 3ksz:R, 3ksz:Q, 3kv3:O, 3kv3:Q, 3kv3:R, 3kv3:P, 3l4s:Q, 3l4s:P, 3l4s:O, 3l4s:R, 3l6o:Q, 3l6o:P, 3l6o:R, 3l6o:O, 3lc1:P, 3lc1:R, 3lc1:O, 3lc1:Q, 3lc2:O, 3lc2:Q, 3lc2:R, 3lc2:P, 3lvf:R, 3lvf:O, 3lvf:Q, 5t73:A, 5t73:B, 5t73:C, 5t73:D, 3vaz:P, 3vaz:R, 3vaz:O, 3vaz:Q, 3vaz:B, 3vaz:A
37 3pym:A 332 336 0.4611 0.4639 0.4583 1.78e-98 3pym:B
38 1a7k:A 358 346 0.5120 0.4777 0.4942 2.57e-98 1a7k:B, 1a7k:C, 1a7k:D, 1gyp:A, 1gyp:B, 1gyp:C, 1gyp:D, 1gyq:A, 1gyq:B, 1gyq:C, 1gyq:D, 1i32:A, 1i32:B, 1i32:C, 1i32:D, 1i32:E, 1i32:F, 1i33:A, 1i33:B, 1i33:C, 1i33:D, 1i33:E, 1i33:F
39 7jwk:C 333 329 0.4551 0.4565 0.4620 3.21e-98 7jwk:A, 7jwk:B, 7jwk:D
40 7www:A 336 339 0.4910 0.4881 0.4838 3.85e-98
41 6qun:O 334 338 0.4731 0.4731 0.4675 2.08e-97 6qun:R, 6quq:O, 6quq:R, 4z0h:O, 4z0h:R
42 3cif:A 338 339 0.4940 0.4882 0.4867 3.35e-97 3cif:B, 3cif:C, 3cif:D, 3cps:A, 3cps:B, 8pvf:A, 1vsv:A, 1vsv:B, 1vsv:C, 1vsv:D
43 8hmn:D 340 340 0.4850 0.4765 0.4765 7.64e-97 8hmn:A, 8hmn:B, 8hmn:C, 6iqm:A, 6iqm:B, 6iqm:C, 6iqm:D
44 5ld5:C 342 337 0.4940 0.4825 0.4896 2.10e-96 5ld5:A, 5ld5:B, 5ld5:D
45 3gpd:R 334 336 0.4760 0.4760 0.4732 3.79e-95 3gpd:G
46 1dss:G 333 328 0.4731 0.4745 0.4817 1.20e-94 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
47 4k9d:A 338 333 0.4910 0.4852 0.4925 2.22e-94 4k9d:B, 4k9d:C, 4k9d:D, 4k9d:E, 4k9d:F, 4k9d:G, 4k9d:H
48 3e5r:O 336 330 0.4641 0.4613 0.4697 2.28e-93 3e5r:A, 3e5r:B, 3e5r:C, 3v1y:O, 3v1y:A, 3v1y:B, 3v1y:C
49 7c5o:O 338 330 0.4581 0.4527 0.4636 8.19e-93 7c5f:O, 7c5f:P, 7c5f:Q, 7c5f:R, 7c5g:O, 7c5g:P, 7c5g:Q, 7c5g:R, 7c5h:O, 7c5h:P, 7c5h:Q, 7c5h:R, 7c5i:O, 7c5i:P, 7c5i:Q, 7c5i:R, 7c5j:O, 7c5j:P, 7c5j:Q, 7c5j:R, 7c5k:O, 7c5k:P, 7c5k:Q, 7c5k:R, 7c5l:O, 7c5l:P, 7c5l:Q, 7c5l:R, 7c5m:O, 7c5m:P, 7c5m:Q, 7c5m:R, 7c5n:O, 7c5n:P, 7c5n:Q, 7c5n:R, 7c5o:P, 7c5o:Q, 7c5o:R, 7c5p:O, 7c5p:P, 7c5p:Q, 7c5p:R, 7c5q:O, 7c5q:P, 7c5q:Q, 7c5q:R, 7c5r:O, 7c5r:P, 7c5r:Q, 7c5r:R, 7c7k:O, 7c7k:P, 7c7k:Q, 7c7k:R
50 6px2:A 332 330 0.4910 0.4940 0.4970 9.08e-92 6px2:B, 6px2:C, 6px2:D, 6px2:E, 6px2:F, 6px2:G, 6px2:H
51 2i5p:O 309 327 0.4371 0.4725 0.4465 1.69e-91 2i5p:P
52 6ok4:A 334 327 0.4401 0.4401 0.4495 2.56e-88 6ok4:B, 6ok4:C, 6ok4:D, 6wyc:A, 6wyc:B, 6wyc:C, 6wyc:D, 6x2e:A, 6x2e:C, 6x2e:D
53 3sth:C 340 332 0.4641 0.4559 0.4669 1.44e-87 3sth:A, 3sth:B, 3sth:D
54 2vyn:D 334 330 0.4401 0.4401 0.4455 1.24e-85 2vyv:D
55 5vmt:E 293 328 0.4491 0.5119 0.4573 3.50e-83
56 3h9e:P 337 330 0.4192 0.4154 0.4242 3.67e-78 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
57 8jb1:A 468 335 0.3743 0.2671 0.3731 1.55e-62 8jb1:B
58 1ys4:A 348 37 0.0419 0.0402 0.3784 0.027 1ys4:B
59 3tz6:A 342 97 0.0719 0.0702 0.2474 0.32 3vos:A
60 3aoe:B 424 49 0.0539 0.0425 0.3673 0.54 3aoe:A, 3aog:A, 3aog:E, 3aog:B, 3aog:D, 3aog:C, 3aog:F, 3aog:G, 3aog:I, 3aog:H, 3aog:J, 3aog:L, 3aog:K
61 3pyl:C 361 95 0.0749 0.0693 0.2632 0.77 2gz1:A, 2gz1:B, 2gz2:A, 2gz2:B, 2gz3:A, 2gz3:B, 2gz3:C, 2gz3:D, 3pwk:A, 3pwk:B, 3pws:A, 3pws:B, 3pyl:A, 3pyl:B, 3pyx:A, 3pyx:B, 3pzb:A, 3pzb:B, 3q11:A, 3q11:B, 3q1l:A, 3q1l:B, 3q1l:C, 3q1l:D, 4r3n:A, 4r3n:B, 4r3w:A, 4r3w:B, 4r41:A, 4r41:B, 4r4j:A, 4r4j:B, 4r51:A, 4r51:B, 4r54:A, 4r54:B, 4r5h:A, 4r5h:B
62 3wyc:A 327 43 0.0539 0.0550 0.4186 1.0 5gz3:A, 5gz3:B, 5gz6:A, 3wyc:B
63 8jw0:Q 162 50 0.0479 0.0988 0.3200 1.7
64 3i5t:A 444 37 0.0449 0.0338 0.4054 2.1 3i5t:B
65 8jw0:C 160 49 0.0479 0.1000 0.3265 2.2 8jw0:T
66 8jw0:O 161 56 0.0569 0.1180 0.3393 2.8 8jze:O
67 7pks:g 886 82 0.0629 0.0237 0.2561 3.6 8rbx:g, 8rbz:g
68 7ycx:G 910 82 0.0629 0.0231 0.2561 3.7
69 2czc:A 334 33 0.0389 0.0389 0.3939 3.7 2czc:B, 2czc:C, 2czc:D
70 3hsk:A 358 152 0.1048 0.0978 0.2303 4.1
71 4mfz:A 319 129 0.0898 0.0940 0.2326 4.2
72 5lr8:A 844 65 0.0629 0.0249 0.3231 5.2 5lr8:B, 5lra:A, 5lra:B, 5lrb:B, 5lrb:A
73 4elq:A 310 62 0.0539 0.0581 0.2903 5.4 4elp:A, 4elp:B, 4elp:C, 4elp:D, 4elq:B, 4elr:A, 4elr:B, 3wae:A, 3wae:B
74 3kv6:D 448 107 0.0749 0.0558 0.2336 5.5 3kv5:D, 3kv5:A, 3kv6:A, 3kv9:A, 3kva:A, 3u78:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218