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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TIHHQIQQALHFRTAVRVYKEEKISDEDLALILDAAWLSPSSIGLEGWRFVVLDNKPIKEEIKPFAWGAQYQLETASHFI
LLIAEKHARYDSPAIKNSLLRRGIKEGDGLNSRLKLYESFQKEDMDMADNPRALFDWTAKQTYIALGNMMMTAALLGIDT
CPIEGFHYDKVNHILAKHNVIDLEKEGIASMLSLGYRLRDPAQVRKPKEEVMSVVK

The query sequence (length=216) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2hay:D 222 218 1.0000 0.9730 0.9908 2.79e-161 2hay:A, 2hay:B, 2hay:C
2 7s14:B 223 215 0.4444 0.4305 0.4465 2.02e-65 7ldq:A, 7rzl:A, 7rzl:B, 7rzp:A, 7rzp:B, 7s14:A, 7s14:C, 7s14:D, 7s1a:A, 7s1a:B, 7t2z:A, 7t2z:B, 7t33:A, 7t33:B
3 6wt2:A 221 213 0.4352 0.4253 0.4413 2.85e-63 6wt2:B, 6wt2:C, 6wt2:D
4 7jh4:A 223 220 0.4491 0.4350 0.4409 2.07e-61 7jh4:B, 7jh4:C, 7jh4:D, 7jh4:E
5 8qyg:B 225 218 0.4306 0.4133 0.4266 3.03e-56 8q5g:A, 8q5g:B, 8qyg:A
6 2h0u:A 196 213 0.3426 0.3776 0.3474 1.02e-28
7 3of4:A 208 211 0.2593 0.2692 0.2654 2.64e-16 3of4:B, 3of4:C
8 1v5y:A 217 231 0.2917 0.2903 0.2727 1.03e-12 1v5y:B, 1v5z:A, 1v5z:B, 1vfr:A, 1vfr:B
9 3bem:B 210 219 0.2731 0.2810 0.2694 1.24e-12 3bem:A
10 3ge6:A 210 164 0.2083 0.2143 0.2744 8.58e-12 3ge6:B
11 3qdl:A 178 209 0.2269 0.2753 0.2344 1.41e-10 3qdl:B, 3qdl:C, 3qdl:D
12 3gbh:B 213 180 0.2176 0.2207 0.2611 3.96e-10 3gbh:A, 3gbh:C, 3gbh:D
13 3eo8:A 219 223 0.2407 0.2374 0.2332 1.44e-08 3eo8:B, 3eo8:C, 3eo8:D, 3eo8:E, 3eo8:F
14 4eo3:A 321 170 0.1898 0.1277 0.2412 1.60e-08 4eo3:B
15 5j8d:A 216 138 0.1759 0.1759 0.2754 4.32e-08 5j8d:B, 5j8d:C, 5j8d:D, 5j8g:A, 5j8g:B, 5j8g:C, 5j8g:D, 1kqb:A, 1kqb:B, 1kqb:C, 1kqb:D, 1kqc:A, 1kqc:B, 1kqc:C, 1kqc:D, 1kqd:A, 1kqd:B, 1kqd:C, 1kqd:D, 1nec:A, 1nec:B, 1nec:C, 1nec:D
16 6czp:A 219 218 0.2315 0.2283 0.2294 5.70e-08 6czp:B, 6czp:C, 6czp:D, 6czp:E, 6czp:F, 6czp:G, 6czp:H, 7uwt:A, 7uwt:B
17 8dor:A 217 164 0.2037 0.2028 0.2683 8.75e-08 8dor:B, 8dor:C, 8dor:D
18 1ds7:A 217 139 0.1806 0.1797 0.2806 2.43e-07 8c5e:A, 8c5e:B, 8c5f:A, 8c5f:B, 8c5p:A, 8c5p:B, 8ccv:A, 8ccv:B, 8cj0:A, 8cj0:B, 1ds7:B, 1icr:A, 1icr:B, 1icu:A, 1icu:B, 1icu:C, 1icu:D, 1icv:A, 1icv:B, 1icv:C, 1icv:D, 1idt:A, 1idt:B, 8og3:A, 8og3:B, 1oo5:A, 1oo5:B, 1oo6:A, 1oo6:B, 1oon:A, 1oon:B, 1ooq:A, 1ooq:B, 8qes:A, 8qes:C, 8qes:B, 8qes:D, 8qpo:A, 8qpo:B, 8qpo:C, 8qpo:G, 8qpo:D, 8qpo:E, 8qpo:F, 8qpo:H, 3x21:A, 3x21:B, 3x21:C, 3x21:D, 3x21:E, 3x21:F, 3x21:G, 3x21:H, 3x21:I, 3x21:J, 3x22:A, 3x22:B, 7x32:A, 7x32:C, 7x32:B, 7x32:H, 7x32:D, 7x32:F, 7x32:E, 7x32:G, 7xww:B, 7xww:A, 7xww:H, 7xww:I, 1yki:A, 1yki:B, 1yki:C, 1yki:D, 1ylr:A, 1ylr:B, 1ylu:A, 1ylu:B
19 3gag:A 206 178 0.2130 0.2233 0.2584 3.83e-07 3gag:B, 3gag:C, 3gag:D
20 5j6c:A 173 79 0.1343 0.1676 0.3671 2.37e-06 5j6c:B
21 1nox:A 200 184 0.2176 0.2350 0.2554 2.52e-06
22 4dn2:A 191 212 0.2176 0.2461 0.2217 5.73e-06 4dn2:B
23 3gfa:A 197 68 0.1019 0.1117 0.3235 6.60e-05 3gfa:B
24 4qlx:A 217 176 0.1806 0.1797 0.2216 2.31e-04 4qlx:B, 4qly:A, 4qly:B, 4qly:C, 4qly:D
25 6pz0:A 185 108 0.1296 0.1514 0.2593 4.58e-04 6pz0:B, 6q1b:A, 6q1b:B, 6q1l:A, 6q1l:B, 6tyk:A, 6tyk:B
26 3e39:A 175 48 0.0833 0.1029 0.3750 5.66e-04 3e39:B
27 2b67:A 201 174 0.1991 0.2139 0.2471 0.001 2b67:B, 2b67:C, 2b67:D
28 3ek3:A 187 66 0.0926 0.1070 0.3030 0.002
29 8uc3:A 180 78 0.0926 0.1111 0.2564 0.003 8uc3:B
30 4g8s:A 182 55 0.0787 0.0934 0.3091 0.003 4g8s:B
31 5j62:B 209 59 0.0741 0.0766 0.2712 0.010 5j62:A
32 8cqt:B 164 79 0.1157 0.1524 0.3165 0.029 8cqt:A
33 3pxv:B 189 85 0.1204 0.1376 0.3059 0.041 3pxv:A, 3pxv:C, 3pxv:D
34 3gr3:A 226 55 0.0694 0.0664 0.2727 0.047 3gr3:B
35 4ttb:A 189 86 0.1065 0.1217 0.2674 0.091 4ttb:B
36 3ge5:A 176 59 0.0694 0.0852 0.2542 0.12 3ge5:B
37 3tnz:A 222 59 0.0787 0.0766 0.2881 0.12 3gfd:A, 3gfd:B, 3gh8:A, 3gh8:B, 3gh8:C, 3gh8:D, 3gh8:E, 3gh8:F, 3gh8:G, 3gh8:H, 3tnz:B
38 4ttc:A 220 59 0.0741 0.0727 0.2712 0.18 4ttc:B, 4ttc:C, 4ttc:D, 4ttc:E, 4ttc:F, 5yak:A, 5yak:F, 5yak:B, 5yak:C, 5yak:D, 5yak:E
39 3kwk:A 168 44 0.0648 0.0833 0.3182 0.24
40 3e10:B 167 78 0.1065 0.1377 0.2949 0.46 3e10:A
41 3m5k:A 168 54 0.0602 0.0774 0.2407 0.46 3m5k:B
42 5ko7:B 200 81 0.1019 0.1100 0.2716 0.53
43 2isj:A 219 195 0.1944 0.1918 0.2154 0.69 2isj:B, 2isj:C, 2isj:D, 2isj:E, 2isj:F, 2isj:G, 2isj:H, 2isk:A, 2isk:B, 2isk:C, 2isk:D, 2isk:E, 2isk:F, 2isk:G, 2isk:H, 2isl:A, 2isl:B, 2isl:C, 2isl:D, 2isl:E, 2isl:F, 2isl:G, 2isl:H
44 3gb5:A 185 52 0.0741 0.0865 0.3077 0.77 3to0:A, 3to0:B
45 2fre:A 200 77 0.1019 0.1100 0.2857 0.81 2fre:B
46 5hei:A 246 152 0.1713 0.1504 0.2434 1.2 5hei:B, 5hei:C, 5hei:D, 5hei:E, 5hei:F, 5hei:G, 5hei:H
47 6eur:B 328 69 0.0972 0.0640 0.3043 2.0 6exf:B
48 5ko8:B 218 56 0.0787 0.0780 0.3036 2.2 5ko7:A, 5ko8:A, 5krd:A, 5krd:B
49 6pt7:A 500 90 0.1204 0.0520 0.2889 3.7
50 1j99:A 284 48 0.0926 0.0704 0.4167 4.0 1efh:A, 1efh:B, 3f3y:A, 3f3y:B, 3f3y:C, 3f3y:D, 4ifb:A, 4ifb:B, 1ov4:A, 2qp3:A, 2qp4:A
51 5dt9:A 379 36 0.0463 0.0264 0.2778 4.7
52 5fzo:A 339 32 0.0509 0.0324 0.3438 8.9 5fzo:B, 2ypd:A, 2ypd:B
53 1ywq:A 199 49 0.0694 0.0754 0.3061 9.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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