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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TIENAKERLNIYKQTNNIRDDYKYTPVGPEHARSFLAELSIYVPALNRTVTARESGSNKKSASKSCALSLVRQLFHLNVI
EPFSGTLKKKKDEQLKPYPVKLSPNLINKIDEVIKGLDLPVVNPESSVIPWAPPQANWNTWHACNIDEGELATTSIDDLS
MDYERSLRDRRQNDNEYRQFLEFREKLPIAAMRSEILTAINDNPVVIIRGNTGCGKTTQIAQYILDDYICSGQGGYANIY
VTQPRRISAISVAERVARERCEQLGDTVGYSVRFESVFPRPYGAILFCTVGVLLRKLEAGLRGVSHIIVDEIHERDVNSD
FLLVILRDMVDTYPDLHVILMSATIDTTKFSKYFGICPVLEVPGRAFPVQQFFLEDIIQMTDFVPSAESEDKDEAEINYN
KVCEDKYSQKTRNAMAMLSESDVSFELLEALLMHIKSKNIPGAILVFLPGWNLIFALMKFLQNTNIFGDTSQYQILPCHS
QIPRDEQRKVFEPVPEGVTKIILSTNIAETSITIDDIVFVIDICKARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRV
RPGFCFTLCSRARFQALEDNLTPEMFRTPLHEMALTIKLLRLGSIHHFLSKALEPPPVDAVIEAEVLLREMRCLDANDEL
TPLGRLLARLPIEPRLGKMMVLGAVFGCADLMAIMASYSSTFSEVFSLDIGQRRLANHQKALSGTKCSDHVAMIVASQMW
RREKQRGEHMEARFCDWKGLQMSTMNVIWDAKQQLLDLLQQAGFPEECMISHEVDERIDGDDPVLDVSLALLCLGLYPNI
CVHKEKRKVLTTESKAALLHKTSVNCSNLAVTFPYPFFVFGEKIRTRAVSCKQLSMVSPLQVILFGSRKIDLAANNIVRV
DNWLNFDIEPELAAKIGALKPALEDLITVACDNPSDILRLEEPYAQLVKVVKDLCVKSAGDFGLQR

The query sequence (length=946) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8pjb:A 962 946 0.9905 0.9740 0.9905 0.0 8b9g:A, 8b9k:A, 8pjj:A
2 5aor:A 1009 982 0.9979 0.9356 0.9613 0.0 5aor:B, 8b9i:A, 8b9j:A
3 8szq:A 861 872 0.4989 0.5482 0.5413 0.0 3llm:A, 3llm:B, 8szp:A, 8szp:B, 8szr:A, 8szs:A
4 5vhe:A 871 774 0.3150 0.3421 0.3850 0.0 6up3:A, 6up4:A, 5vhc:D, 5vhd:D
5 5n9d:B 866 729 0.2653 0.2898 0.3443 7.19e-127 5n8r:A, 5n8r:B, 5n8s:A, 5n8s:B, 5n8u:A, 5n8u:B, 5n8z:A, 5n8z:B, 5n90:A, 5n90:B, 5n94:A, 5n94:B, 5n96:A, 5n96:B, 5n98:A, 5n98:B, 5n9a:A, 5n9a:B, 5n9d:A, 5n9e:A, 5n9e:B, 5n9f:A, 5n9f:B
6 6i3p:C 630 651 0.2252 0.3381 0.3272 1.81e-89 6i3p:A, 6i3p:B, 6i3p:D, 6qic:A, 6qic:B, 6qic:C, 6qic:D
7 7qtt:N 792 650 0.2125 0.2538 0.3092 1.15e-85 8ch6:N
8 8i0s:X 786 587 0.2008 0.2417 0.3237 1.06e-84 8i0t:X, 8i0u:X, 8i0v:X
9 8c6j:V 934 586 0.2008 0.2034 0.3242 7.30e-82 6hys:A, 6hys:B, 6hys:C, 6hys:D, 6hyt:A, 6hyt:B, 6hyt:C, 6hyt:D, 6hyu:A
10 7b9v:Q 624 596 0.2040 0.3093 0.3238 4.45e-80
11 5d0u:A 705 732 0.2230 0.2993 0.2883 7.20e-80 5lta:A, 5ltj:A, 5ltk:A, 6qid:A, 6qie:A
12 3kx2:B 755 638 0.2030 0.2543 0.3009 5.51e-79 5i8q:A, 5i8q:B, 5jpt:A, 5jpt:B, 3kx2:A, 2xau:A, 2xau:B, 5y88:W
13 6bk8:P 653 564 0.1903 0.2757 0.3191 9.03e-79 6exn:V, 5mq0:V
14 8cnt:A 620 583 0.1934 0.2952 0.3139 1.82e-78
15 7dcp:x 670 592 0.1966 0.2776 0.3142 1.61e-76 7dco:x, 7dd3:x
16 6rm8:A 655 554 0.1903 0.2748 0.3249 4.58e-76 6fa5:A, 6faa:A, 6fac:A, 6rm9:A, 6rma:A, 6rmb:A, 6rmc:A, 6rmc:B, 6zm2:A
17 6sh6:A 681 600 0.1956 0.2717 0.3083 1.59e-74 8ejm:A, 8ro2:DX, 5xdr:A
18 8ro1:DX 682 585 0.1892 0.2625 0.3060 2.50e-72
19 6hyu:C 585 572 0.1797 0.2906 0.2972 2.59e-68
20 5gm6:Y 598 589 0.1850 0.2926 0.2971 2.30e-67
21 8po7:A 594 502 0.1712 0.2727 0.3227 8.12e-67
22 6zww:C 749 598 0.1913 0.2417 0.3027 2.04e-65 8po7:B, 8po8:A, 8po8:B, 6zww:A, 6zww:E, 6zww:G
23 6zqg:JD 829 520 0.1797 0.2051 0.3269 5.78e-64
24 7aju:JD 811 570 0.1882 0.2195 0.3123 1.24e-62 6zqd:JD, 6zqe:JD, 6zqf:JD
25 6h57:A 795 533 0.1818 0.2164 0.3227 6.37e-62
26 7d63:RZ 839 548 0.1776 0.2002 0.3066 5.58e-58 7d4i:RZ, 7d5t:RZ, 7mqj:A
27 7mqa:NS 914 605 0.1860 0.1926 0.2909 3.68e-50 6o16:A, 6o16:B
28 5ztm:A 168 82 0.0867 0.4881 1.0000 3.04e-48 5ztm:B
29 6heg:A 783 484 0.1543 0.1865 0.3017 4.11e-47
30 3vyx:A 95 85 0.0560 0.5579 0.6235 4.96e-31
31 6evj:B 752 164 0.0455 0.0572 0.2622 0.13 6evj:E, 6evk:B, 9f2r:B, 9f37:B, 6fhh:B, 6fhi:B, 5m3h:B, 6szu:B, 6szv:B, 6t0n:B, 6t0r:B, 6t0s:B, 6t0u:B, 6t0v:B, 6t2c:B, 6tw1:B, 4wsb:B
32 6yyi:B 502 109 0.0307 0.0578 0.2661 1.4
33 1ky2:A 180 65 0.0180 0.0944 0.2615 1.9 1ky3:A, 4phf:A, 4phg:A, 4phh:A, 4phh:B, 4phh:C, 4phh:D
34 4fmw:A 178 71 0.0211 0.1124 0.2817 2.2 4fmw:B
35 1uaa:A 636 67 0.0222 0.0330 0.3134 3.0 1uaa:B
36 2iw3:B 980 64 0.0275 0.0265 0.4062 3.3 7b7d:EF, 2iw3:A, 2iwh:A, 2iwh:B
37 4b3g:A 614 97 0.0285 0.0440 0.2784 4.1 4b3g:B
38 6ui4:A 692 39 0.0190 0.0260 0.4615 4.4
39 8exs:A 556 65 0.0190 0.0324 0.2769 5.2 8c0p:A, 8c0p:B, 8c0s:A, 8c0s:B, 8cf3:C, 8cf3:E, 8exp:A, 8exp:B, 8exq:B, 8exq:A, 8exr:B, 8exr:A, 8exs:B, 8ext:A, 8ext:B, 6o9w:B, 3q7z:A, 3q7z:B, 3q81:A, 3q81:B, 3q82:A, 3q82:B, 1xa1:A, 1xa1:B, 1xa1:C, 1xa1:D, 1xa7:A, 1xa7:B, 1xkz:A, 1xkz:B, 1xkz:C, 1xkz:D
40 6ftl:A 482 53 0.0180 0.0353 0.3208 6.2 6ftl:C, 6ftl:E, 6ftl:G, 5mz2:A, 5mz2:B, 5mz2:C, 5mz2:D, 5mz2:H, 5mz2:G, 5mz2:F, 5mz2:E, 5n9z:A, 5n9z:B, 5n9z:H, 5n9z:G, 5n9z:F, 5n9z:E, 5n9z:D, 5n9z:C, 5oya:A, 5oya:B, 5oya:C, 5oya:D, 5oya:E, 5oya:F, 5oya:G, 5oya:H, 7yk5:G, 7yk5:F, 7yk5:E, 7yk5:D, 7yk5:C, 7yk5:B, 7yk5:A, 7yk5:H
41 3f46:A 345 30 0.0127 0.0348 0.4000 6.4 3daf:A, 3dag:A, 3f47:A, 3h65:A
42 1ri1:A 252 42 0.0180 0.0675 0.4048 6.4 2hv9:A, 1ri2:A, 1ri3:A, 1ri4:A, 1z3c:A
43 8ez4:C 525 82 0.0211 0.0381 0.2439 9.9 5cbm:A, 5cbm:B, 5cbm:C, 5cbm:D, 5cbm:E, 5cbm:F, 5cbm:G, 5cbm:H, 5cbm:I, 5cbm:J, 5cbm:K, 5cbm:L, 6ee2:A, 6ee2:B, 6ee2:C, 6ee2:D, 6ee2:E, 6ee2:F, 6ee2:G, 6ee2:H, 6ee2:I, 6ee2:J, 6ee2:K, 6ee2:L, 6eee:A, 6eee:B, 6eee:C, 6eee:D, 6eee:E, 6eee:F, 6eee:G, 6eee:H, 6eee:I, 6eee:J, 6eee:K, 6eee:L, 8ez4:A, 8ez4:B, 8ez4:D, 8ez4:E, 8ez4:F, 8ez4:G, 8ez4:H, 8ez4:I, 8ez4:J, 8ez4:K, 8ez4:L, 4k3n:A, 4k3n:B, 4k3n:C, 4k3n:D, 4k3n:E, 4k3n:F, 4k3n:G, 4k3n:H, 4k3n:I, 4k3n:J, 4k3n:K, 4k3n:L, 3kqx:A, 3kqx:B, 3kqx:C, 3kqx:D, 3kqx:E, 3kqx:F, 3kqx:G, 3kqx:H, 3kqx:I, 3kqx:J, 3kqx:K, 3kqx:L, 3kqz:A, 3kqz:B, 3kqz:C, 3kqz:D, 3kqz:E, 3kqz:F, 3kqz:G, 3kqz:H, 3kqz:I, 3kqz:J, 3kqz:K, 3kqz:L, 3kr4:A, 3kr4:B, 3kr4:C, 3kr4:D, 3kr4:E, 3kr4:F, 3kr4:G, 3kr4:H, 3kr4:I, 3kr4:J, 3kr4:K, 3kr4:L, 3kr5:A, 3kr5:B, 3kr5:C, 3kr5:D, 3kr5:E, 3kr5:F, 3kr5:G, 3kr5:H, 3kr5:I, 3kr5:J, 3kr5:K, 3kr5:L, 4r6t:A, 4r6t:B, 4r6t:C, 4r6t:D, 4r6t:E, 4r6t:F, 4r6t:G, 4r6t:H, 4r6t:I, 4r6t:J, 4r6t:K, 4r6t:L, 4r76:A, 4r76:B, 4r76:C, 4r76:D, 4r76:E, 4r76:F, 4r76:G, 4r76:H, 4r76:I, 4r76:J, 4r76:K, 4r76:L, 4r7m:A, 4r7m:B, 4r7m:C, 4r7m:D, 4r7m:E, 4r7m:F, 4r7m:G, 4r7m:H, 4r7m:I, 4r7m:J, 4r7m:K, 4r7m:L, 7rie:A, 7rie:B, 7rie:C, 7rie:D, 7rie:E, 7rie:F, 7rie:G, 7rie:H, 7rie:I, 7rie:J, 7rie:K, 7rie:L, 7srv:A, 7srv:B, 7srv:C, 7srv:D, 7srv:E, 7srv:F, 8svm:A, 8svm:B, 8svm:C, 8svm:D, 8svm:E, 8svm:F, 8svm:G, 8svm:H, 8svm:I, 8svm:J, 8svm:K, 8svm:L, 8sw9:A, 8sw9:B, 8sw9:C, 8sw9:D, 8sw9:E, 8sw9:F, 8sw9:G, 8sw9:H, 8sw9:I, 8sw9:J, 8sw9:K, 8sw9:L, 7t3v:A, 7t3v:B, 7t3v:C, 7t3v:D, 7t3v:E, 7t3v:F, 3t8w:A, 3t8w:B, 3t8w:E, 3t8w:C, 3t8w:D, 3t8w:F, 3t8w:G, 3t8w:H, 3t8w:K, 3t8w:I, 3t8w:J, 3t8w:L, 4x2t:A, 4x2t:B, 4x2t:C, 4x2t:D, 4x2t:E, 4x2t:F, 4x2t:G, 4x2t:H, 4x2t:I, 4x2t:J, 4x2t:K, 4x2t:L, 4zx8:A, 4zx8:B, 4zx8:C, 4zx8:D, 4zx8:E, 4zx8:F, 4zx8:G, 4zx8:H, 4zx8:I, 4zx8:J, 4zx8:K, 4zx8:L, 4zx9:A, 4zx9:B, 4zx9:C, 4zx9:D, 4zx9:E, 4zx9:F, 4zx9:G, 4zx9:H, 4zx9:I, 4zx9:J, 4zx9:K, 4zx9:L, 4zy0:A, 4zy0:B, 4zy0:C, 4zy0:D, 4zy0:E, 4zy0:F, 4zy0:G, 4zy0:H, 4zy0:I, 4zy0:J, 4zy0:K, 4zy0:L, 4zy1:A, 4zy1:B, 4zy1:C, 4zy1:D, 4zy1:E, 4zy1:F, 4zy1:G, 4zy1:H, 4zy1:I, 4zy1:J, 4zy1:K, 4zy1:L, 4zy2:A, 4zy2:B, 4zy2:C, 4zy2:D, 4zy2:E, 4zy2:F, 4zy2:G, 4zy2:H, 4zy2:I, 4zy2:J, 4zy2:K, 4zy2:L, 4zyq:A, 4zyq:B, 4zyq:C, 4zyq:D, 4zyq:E, 4zyq:F, 4zyq:G, 4zyq:H, 4zyq:I, 4zyq:J, 4zyq:K, 4zyq:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218