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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
THFGGLKDEDRIFTNLYGLHDPFLKGAMKRGDWHRTKDLVLKGTDWIVNEMKKSGLRGRGGAGFPSGLKWSFMPKVSDGR
PSYLVVNADESEPGTCKDREIMRHDPHKLLEGCLIAGVGMRASAAYIYIRGEYVNERLNLEKARREAYAAGLLGKNACGS
GYDFEVYIHFGAGAYICGEETALLESLEGKQGKPRLKPPFPANAGLYGCPTTVTNVETVAVSPTILRRGPEWFSSFGRKN
NAGTKLFCISGHVNKPCTVEEEMSIPLKELIERHCGGVRGGWDNLLAIIPGGSSVPLIPKNICEDVLMDFDALKAVQSGL
GTAAVIVMDKSTDVVDAIARLSYFYKHESCGQCTPCREGTGWLWMIMERMKVGNAKLEEIDMLQEVTKQIEGHTICALGD
AAAWPVQGLIRHFRPELERRIRERAEREL

The query sequence (length=429) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7aqr:F 434 429 1.0000 0.9885 1.0000 0.0 7a23:A, 7a24:A, 7ar7:F, 7ar8:F, 7arb:F, 8bed:F, 8bpx:F, 8bq5:F, 8bq6:F, 8e73:V1, 6x89:V1
2 7arc:F 430 422 0.8112 0.8093 0.8246 0.0 7ard:F
3 8b9z:F 441 427 0.7692 0.7483 0.7728 0.0 8ba0:F, 8esw:V1, 8esz:V1
4 8gym:v1 442 420 0.7622 0.7398 0.7786 0.0 8b6f:AD, 8bqs:AD, 8gym:V1, 8gzu:v1, 8gzu:V1, 7tgh:V1
5 7v2c:A 433 425 0.7529 0.7460 0.7600 0.0 7ak5:F, 7ak6:F, 7b93:F, 8c2s:F, 8ca3:F, 8ca4:F, 8ca5:F, 7dgq:8, 7dgr:8, 7dgs:8, 7dgz:8, 7dh0:8, 7dkf:82, 6g2j:F, 6g72:F, 5gpn:c, 5gup:B, 8iao:F, 8iap:F, 8ib4:F, 8ib5:F, 8ib9:F, 8iba:F, 8ibd:F, 8ibe:F, 8ic2:F, 8ic3:F, 5lc5:F, 5ldw:F, 5ldx:F, 5lnk:1, 5o31:F, 8olt:F, 8om1:F, 7psa:F, 8pw5:1, 8pw6:1, 8pw7:1, 8q0a:F, 8q0f:F, 8q0j:F, 8q0m:F, 8q0o:F, 8q0q:F, 8q1p:F, 8q1u:F, 8q1y:F, 8q25:F, 8q45:F, 8q46:F, 8q47:F, 8q48:F, 8q49:F, 8q4a:F, 6q9d:V1, 6qa9:V1, 6qbx:V1, 6qc2:V1, 6qc3:V1, 6qc4:V1, 6qc5:V1, 6qc6:V1, 6qc7:V1, 6qc8:V1, 6qc9:V1, 6qca:V1, 6qcf:V1, 7qsd:F, 7qsk:F, 7qsl:F, 7qsm:F, 7qsn:F, 7qso:F, 7r41:F, 7r42:F, 7r43:F, 7r44:F, 7r45:F, 7r46:F, 7r47:F, 7r48:F, 7r4c:F, 7r4d:F, 7r4f:F, 7r4g:F, 8rgp:1, 8rgq:1, 8rgr:1, 8rgt:1, 8ud1:1F, 8ueo:1F, 8uep:1F, 8ueq:1F, 8uer:1F, 8ues:1F, 8uet:1F, 8ueu:1F, 8uev:1F, 8uew:1F, 8uex:1F, 8uey:1F, 8uez:1F, 8ugh:1F, 8ugi:1F, 8ugj:1F, 8ugn:1F, 8ugn:5F, 8ugr:1F, 8ugr:5F, 7v2d:A, 7v2e:A, 7v2f:A, 7v2h:A, 7v2k:A, 7v2r:A, 7v30:A, 7v31:A, 7v32:A, 7v33:A, 7v3m:A, 7vb7:A, 7vbn:A, 7vbz:A, 7vwj:A, 7vxp:A, 7vxu:A, 7vy8:A, 7vya:A, 7vyf:A, 7vyh:A, 7vyn:A, 7vz1:A, 7vzv:A, 7vzw:A, 7w00:A, 7w0h:A, 7w0r:A, 7w0y:A, 7w1o:A, 7w1p:A, 7w1t:A, 7w1u:A, 7w1v:A, 7w1z:A, 7w20:A, 7w2k:A, 7w2l:A, 7w2r:A, 7w2u:A, 7w2y:A, 7w31:A, 7w32:A, 7w35:A, 7w4c:A, 7w4d:A, 7w4e:A, 7w4f:A, 7w4g:A, 7w4j:A, 7w4k:A, 7w4l:A, 7w4m:A, 7w4n:A, 7w4q:A, 5xtb:A, 5xtd:A, 5xth:A, 5xti:A, 5xti:BA, 7zd6:1, 7zdh:1, 7zdj:1, 7zdm:1, 7zdp:1, 7zeb:1, 6zk9:1, 6zkc:1, 6zkd:1, 6zke:1, 6zkf:1, 6zkg:1, 6zkh:1, 6zki:1, 6zkj:1, 6zkk:1, 6zkl:1, 6zkm:1, 6zkn:1, 6zko:1, 6zkp:1, 6zkq:1, 6zkr:1, 6zks:1, 6zkt:1, 6zku:1, 6zkv:1, 6zr2:F, 6ztq:F
6 7zm7:B 456 427 0.7366 0.6930 0.7400 0.0 7zmb:B, 7zmg:B
7 7b0n:F 460 426 0.7226 0.6739 0.7277 0.0 6gcs:B, 7o6y:B, 7o71:B, 6rfq:B, 6rfr:B, 6rfs:B, 6y79:B, 6yj4:F
8 8iuf:V1 504 425 0.7086 0.6032 0.7153 0.0 8j9h:V1, 8j9i:V1, 8j9j:V1
9 8qby:F 421 419 0.6807 0.6936 0.6969 0.0
10 4hea:1 437 402 0.4452 0.4371 0.4751 8.85e-125 2fug:1, 2fug:A, 2fug:J, 2fug:S, 4hea:B, 6i0d:1, 6i0d:B, 6i1p:1, 6i1p:B, 3i9v:1, 3i9v:A, 3iam:1, 3iam:A, 3ias:1, 3ias:A, 3ias:J, 3ias:S, 3m9s:1, 3m9s:A, 6q8o:1, 6q8o:B, 6q8w:1, 6q8w:B, 6q8x:1, 6q8x:B, 6y11:1, 6y11:B, 2ybb:1, 6ziy:1, 6zjl:1, 6zjn:1, 6zjy:1
11 8e9h:F 436 414 0.4569 0.4495 0.4734 1.07e-118 8e9g:F, 8e9i:F
12 7p61:F 442 380 0.3893 0.3778 0.4395 5.17e-107 7awt:F, 7nyr:F, 7nyu:F, 7nyv:F, 7nz1:F, 7p62:F, 7p63:F, 7p64:F, 7p69:F, 7p7c:F, 7p7e:F, 7p7j:F, 7p7k:F, 7p7l:F, 7p7m:F, 7z7r:F, 7z7s:F, 7z7t:F, 7z7v:F, 7z80:F, 7z83:F, 7z84:F, 7zc5:F, 7zci:F
13 9fdv:B 419 397 0.3986 0.4081 0.4307 4.40e-93 9fdj:B, 9fdj:D, 9fdk:B, 9fdk:D, 9fdv:D, 9fe0:B, 9fe0:D, 9fe5:B, 9fe5:D, 9fe7:B, 9fe7:D, 9fe8:B, 9fe8:D, 9fea:B, 9fea:D, 9fif:B, 9fif:D, 9fih:B, 9fih:D, 9fii:B, 9fii:D, 9fij:B, 9fij:D, 9fil:B, 9fil:D, 6hl2:B, 6hl2:D, 6hl3:B, 6hl3:D, 6hl4:B, 6hl4:D, 6hla:B, 6hla:D, 6hli:B, 6hli:D, 6hlj:B, 6hlj:D, 6hlm:B, 6hlm:D, 7q5y:C, 7q5y:I, 7q5y:O, 7q5y:U, 6q9c:B, 6q9c:D, 6q9g:B, 6q9g:D, 6q9j:B, 6q9j:D, 6q9k:B, 6q9k:D, 8qg1:B, 8qg1:D, 8qgw:B, 8qgw:D, 8qh4:B, 8qh4:D, 8qh7:B, 8qh7:D, 8qhk:B, 8qhk:D, 6r7p:B, 6r7p:D, 6saq:B, 6saq:D
14 8a6t:B 630 378 0.3660 0.2492 0.4153 5.44e-92 8a6t:E, 8bew:B, 8bew:E
15 7t2r:B 425 378 0.3450 0.3482 0.3915 3.46e-87 7t2r:G, 7t30:B, 7t30:G
16 7q4v:B 599 379 0.3730 0.2671 0.4222 4.56e-87 8a5e:B, 7q4v:F, 7q4w:B, 7q4w:F
17 7p8n:B 613 388 0.3636 0.2545 0.4021 1.11e-84 7p5h:B, 7p5h:E, 7p5h:b, 7p5h:e, 7p8n:b, 7p91:b, 7p91:B, 7p92:B
18 8oh5:B 584 421 0.3846 0.2825 0.3919 2.99e-82 8oh5:E, 8oh5:H, 8oh5:K, 8oh9:B, 8oh9:E, 8oh9:H, 8oh9:K
19 6vw7:D 514 413 0.3497 0.2918 0.3632 4.64e-76 6vw7:B, 6vw8:B, 6vw8:D
20 7vw6:B 560 354 0.3124 0.2393 0.3785 1.83e-72 7e5z:B, 8j83:B, 7xqw:B
21 6tg9:B 493 370 0.3333 0.2901 0.3865 2.07e-65 6tg9:F, 6tga:B, 6tga:F
22 5xfa:A 581 385 0.3170 0.2341 0.3532 1.37e-62 5xf9:A, 5xf9:E, 5xfa:E
23 4wz7:B 370 51 0.0723 0.0838 0.6078 1.23e-09 6h8k:B
24 4wz7:B 370 59 0.0583 0.0676 0.4237 3.50e-04 6h8k:B
25 7zc6:C 435 111 0.0793 0.0782 0.3063 5.16e-06
26 8rbq:C 477 276 0.1515 0.1363 0.2355 0.011 8ahx:C, 8rb8:C, 8rb9:C, 8rbm:C
27 6zt3:A 394 39 0.0303 0.0330 0.3333 0.31 4bae:A, 4bae:B, 4bae:C, 4bae:D
28 3sxq:A 519 96 0.0606 0.0501 0.2708 0.56 3sxq:B, 3ttb:A, 3ttb:B
29 3qcp:A 410 86 0.0536 0.0561 0.2674 1.5 3qd9:A, 3qd9:B, 3qd9:C, 3qd9:D
30 1l1y:A 642 52 0.0420 0.0280 0.3462 2.1 1l1y:B, 1l1y:C, 1l1y:D, 1l1y:E, 1l1y:F, 1l2a:A, 1l2a:B, 1l2a:C, 1l2a:D, 1l2a:E, 1l2a:F, 5yj6:A
31 4by9:F 366 56 0.0373 0.0437 0.2857 3.9 4by9:I, 4by9:C, 4by9:L, 3nmu:A, 3nmu:B, 3nvi:A, 3nvi:C, 3nvk:A, 3nvk:F
32 3qz1:A 445 77 0.0559 0.0539 0.3117 4.7 3qz1:B, 3qz1:C, 3qz1:D
33 1w6u:A 288 34 0.0280 0.0417 0.3529 5.3 1w6u:B, 1w6u:C, 1w6u:D, 1w73:A, 1w73:B, 1w73:C, 1w73:D, 1w8d:A, 1w8d:B, 1w8d:C, 1w8d:D
34 7ucw:B 281 32 0.0256 0.0391 0.3438 8.7 7ucw:A, 7ucw:C, 7ucw:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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