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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TGWKDIPPVPTAQEFIDIVLSRTQRRLPTQIRPGFKISRIRAFYTRKVKFTQETCSEKFGAIISSFPVLSDQHPFHRDLM
NILYDADHFKVALGQISTAKNLIETISRDYVRLLKYAQSLYQCKQLKRAALGRMATLIKRLKDPLIYLDQVRQHLARLPD
INPTTRTLLVAGFPNVGKSSFVRSVTRADTPVEPYAFTTKSLFVGHLDYKYLRYQVIDTPGILDHPLEEMNTIEMQSVTA
LAHLRAAVLYFMDISEQCGFSLKAQINLFKSIKPLFANKMVFIVLNKMDIKKFEELDPEMQQEINDLTKSGEVEILRASC
ATQEGVQEVKNHVCERLLVERVSQKLKAGTHSNGNIGTRLQEVMARIHVATPMDGTTRETFIPEAVKNLKKYDKNDPNRR
VLARDIEEANGGAGVFNVDLRKDWILENPEWKYDKIPEIFDGKNVYDYIDPDIDAKLQALEEEEERLEKEGFYDEDEEEE
EILQKAEYIREQHALIRNEAKMRKSLKNRAIIPRKAVKKPLSQLEDHLDQLGVDTEAIGLRA

The query sequence (length=542) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8pv1:CH 627 543 1.0000 0.8644 0.9982 0.0 8i9r:CH, 8i9t:CH, 8i9v:CH, 8i9w:CH, 8i9x:CH, 8i9y:CH, 8i9z:CH, 8ia0:CH, 8pv2:CH, 8pv3:CH, 8pv4:CH, 8pv5:CH, 8pv6:CH, 8pv7:CH, 8pv8:CH, 8pvk:CH, 8pvl:CH
2 8hfr:rA 647 550 0.5996 0.5023 0.5909 0.0 7bt6:b, 7btb:b, 6c0f:W, 6ft6:b, 3jct:b, 5jcs:o, 6m62:b, 6n8j:b, 6n8k:b, 7nad:b, 7oh3:b, 7ohq:b, 7oht:b, 7r72:b, 7u0h:b, 7ug6:b, 7uoo:b, 7uqb:b, 7uqz:b, 7v08:b, 4v7f:o, 8v87:b, 6ylx:b, 6yly:b, 7z34:b
3 6ylg:b 613 544 0.5793 0.5122 0.5772 0.0 7nac:b, 7of1:b, 7r7a:b, 6ylh:b
4 8v83:b 423 472 0.5148 0.6596 0.5911 0.0 6elz:b, 6em1:b, 6em5:b, 7ohp:b, 7ohr:b, 7ohs:b, 7ohu:b, 7ohv:b, 8v84:b
5 8ir1:4 620 542 0.5295 0.4629 0.5295 0.0 8fkt:SR, 8fku:SR, 8fkv:SR, 8fkw:SR, 8fkx:SR, 8fky:SR, 8fkz:SR, 8fl0:SR, 8fl2:SR, 8fl3:SR, 8fl6:SR, 8fl7:SR, 8fl9:SR, 8fla:SR, 8flb:SR, 8flc:SR, 8fld:SR, 8fle:SR, 8flf:SR, 8idt:4, 8idy:4, 8ie3:4, 8ine:4, 8inf:4, 8ink:4, 8ipd:4, 8ipx:4, 8ipy:4, 8ir3:4, 6lss:4, 6lu8:4
6 8etc:b 415 454 0.4815 0.6289 0.5749 0.0 8esq:b, 8etj:b
7 8fl4:SR 593 540 0.5240 0.4789 0.5259 9.76e-179 8fkr:SR, 8fks:SR
8 8eti:b 391 455 0.4428 0.6138 0.5275 1.14e-163 8esr:b, 8etg:b
9 7ohy:b 375 473 0.4465 0.6453 0.5116 5.23e-154
10 7ohx:b 248 280 0.2269 0.4960 0.4393 5.40e-64
11 7ohx:b 248 64 0.0812 0.1774 0.6875 8.96e-17
12 7ohw:b 259 297 0.2214 0.4633 0.4040 1.99e-61
13 7ohw:b 259 55 0.0683 0.1429 0.6727 4.97e-11
14 2e87:A 356 345 0.1956 0.2978 0.3072 7.71e-55
15 6n8l:b 248 180 0.1882 0.4113 0.5667 2.46e-52
16 2qu8:A 194 181 0.1513 0.4227 0.4530 2.55e-44
17 8eup:b 151 152 0.1421 0.5099 0.5066 4.55e-39
18 8eup:b 151 37 0.0406 0.1457 0.5946 3.58e-11
19 8euy:b 120 126 0.1052 0.4750 0.4524 1.22e-24
20 8euy:b 120 37 0.0406 0.1833 0.5946 5.93e-11
21 7r7c:b 54 41 0.0554 0.5556 0.7317 1.49e-14
22 7naf:b 74 40 0.0535 0.3919 0.7250 4.21e-12
23 7naf:b 74 40 0.0369 0.2703 0.5000 0.093
24 7oi6:y 331 198 0.1033 0.1692 0.2828 1.94e-07 8pk0:t
25 7o9k:G 337 171 0.0886 0.1424 0.2807 4.09e-07 7of5:x, 7of7:x
26 7rr5:R 355 94 0.0517 0.0789 0.2979 4.01e-06
27 7nrc:So 347 78 0.0517 0.0807 0.3590 1.25e-05
28 1wf3:A 296 151 0.0756 0.1385 0.2715 9.17e-05
29 7bl2:9P1 338 127 0.0701 0.1124 0.2992 1.85e-04 7bl3:9P, 7bl4:9, 7bl5:9, 7bl6:9, 4csu:9, 5m04:A
30 2wjg:A 170 162 0.0664 0.2118 0.2222 0.002 2wjg:B, 2wjh:A, 2wjh:B, 2wji:A, 2wji:B, 2wjj:A, 2wjj:B
31 3iev:A 302 123 0.0683 0.1225 0.3008 0.018 7c1o:A, 3r9w:A, 3r9x:A
32 5m7h:A 420 167 0.0867 0.1119 0.2814 0.031 4dcs:A, 4dct:A, 4dcu:A, 2hjg:A, 5mbs:A, 5x4b:A, 5x4b:B
33 6g0z:A 290 115 0.0517 0.0966 0.2435 0.040 6g0z:B, 6g12:A, 6g12:B, 6g14:B, 6g14:A, 6g15:A, 6g15:B
34 2gj8:D 172 171 0.0793 0.2500 0.2515 0.053 2gj8:A, 2gj8:B, 2gj8:C, 2gj9:A, 2gj9:B, 2gj9:C, 2gj9:D, 2gja:A, 2gja:B
35 8fkt:NB 387 73 0.0424 0.0594 0.3151 0.055 8fkp:NB, 8fku:NB, 8fkv:NB, 8fkw:NB, 8fkx:NB, 8fky:NB, 8fkz:NB, 8fl0:NB, 8ink:u, 8ipd:u, 8ipx:u, 8ipy:u
36 5ee3:B 364 30 0.0258 0.0385 0.4667 0.063 5ee3:A, 5ee9:A
37 1lnz:A 342 173 0.0775 0.1228 0.2428 0.077 1lnz:B
38 7y9i:A 362 30 0.0221 0.0331 0.4000 0.29
39 7aju:CL 808 73 0.0387 0.0260 0.2877 0.31 6zqd:CL, 6zqe:CL, 6zqf:CL, 6zqg:CL
40 3w5j:A 194 53 0.0314 0.0876 0.3208 0.33
41 7wtl:CL 610 73 0.0387 0.0344 0.2877 0.36 5wyj:B1, 5wyk:B1
42 3pqc:B 194 55 0.0332 0.0928 0.3273 0.38 3pqc:A
43 2dby:A 355 36 0.0277 0.0423 0.4167 0.39
44 1mky:A 407 91 0.0498 0.0663 0.2967 0.40
45 3a1s:A 255 166 0.0683 0.1451 0.2229 0.42 3a1s:B, 3a1t:A, 3a1u:A, 3a1u:B
46 1xzq:A 449 124 0.0480 0.0579 0.2097 0.44 1xzq:B
47 7odt:t 316 171 0.0793 0.1361 0.2515 0.51
48 4zu9:A 582 172 0.0812 0.0756 0.2558 0.71
49 6rxt:CI 822 145 0.0664 0.0438 0.2483 0.79 6rxu:CI, 6rxv:CI, 6rxx:CI, 6rxy:CI, 6rxz:CI
50 3jce:x 586 129 0.0738 0.0683 0.3101 1.2 3deg:C
51 5ub8:A 174 54 0.0314 0.0977 0.3148 1.2
52 6xrs:B 392 73 0.0480 0.0663 0.3562 1.6 6xrs:A, 6xrs:D, 6xrs:C
53 6xrs:B 392 141 0.0664 0.0918 0.2553 5.4 6xrs:A, 6xrs:D, 6xrs:C
54 7zgz:X 753 83 0.0369 0.0266 0.2410 1.8 8c7f:B
55 1puj:A 261 67 0.0332 0.0690 0.2687 1.9 6ppk:W
56 8i9w:CL 397 86 0.0480 0.0655 0.3023 1.9 8i9t:CL, 8i9v:CL, 8i9x:CL, 8i9y:CL, 8i9z:CL, 8ia0:CL, 8pv1:CL, 8pv2:CL, 8pv3:CL, 8pv4:CL, 8pv5:CL, 8pv6:CL, 8pv7:CL, 8pv8:CL, 8pvk:CL, 8pvl:CL
57 8fl2:NC 511 81 0.0443 0.0470 0.2963 2.0 8fkz:NC, 8fl0:NC, 8fl3:NC, 8fl4:NC, 8idt:A, 8idy:A, 8ie3:A, 8ine:A, 8inf:A, 8ink:w, 8ipd:w, 8ipx:w, 8ipy:w, 8ir1:w, 8ir3:w
58 4lr7:A 391 94 0.0461 0.0639 0.2660 2.3 4lr7:B, 4lr7:C, 4lr8:A, 4lr8:B, 4lr8:C, 4lr9:A, 4lr9:B, 4lr9:C, 4lra:A, 4lra:B, 4lra:C, 4lrb:A, 4lrb:B, 4lrb:C, 4lrc:A, 4lrc:B, 4lrc:C, 4lrd:A, 4lre:A, 4lre:B, 4lre:C, 4lrf:A, 4lrf:B, 4lrf:C, 3m8w:A, 3m8w:B, 3m8w:C, 3m8y:A, 3m8y:B, 3m8y:C, 3m8z:A, 3m8z:B, 3m8z:C, 3ot9:A, 3ot9:B, 3ot9:C, 3twz:A, 3tx0:A, 3un2:A, 3un2:B, 3un2:C, 3un3:A, 3un3:B, 3un3:C, 3un5:A, 3un5:B, 3un5:C, 3un5:D, 3un5:E, 3un5:F, 3uny:A, 3uny:B, 3uny:C, 3uny:D, 3uny:E, 3uny:F, 3uo0:A, 3uo0:B, 3uo0:C
59 3fwy:A 268 48 0.0295 0.0597 0.3333 2.5 3fwy:B, 6uyk:A, 6uyk:B, 6uyk:C, 6uyk:D
60 1oao:C 729 34 0.0258 0.0192 0.4118 3.1 3git:A, 3git:B, 3git:C, 3git:D, 3git:E, 3git:F, 3i01:M, 3i01:N, 3i01:O, 3i01:P, 3i04:M, 3i04:N, 3i04:O, 3i04:P, 1mjg:M, 1mjg:N, 1mjg:O, 1mjg:P, 1oao:D, 6x5k:M, 6x5k:N, 6x5k:O, 6x5k:P, 2z8y:M, 2z8y:N, 2z8y:O, 2z8y:P
61 7pjx:x 522 119 0.0572 0.0594 0.2605 3.5
62 7ajt:CL 781 62 0.0332 0.0230 0.2903 3.6 7d5s:RJ, 6zqa:CL, 6zqb:CL, 6zqc:CL
63 8pv1:Cd 462 54 0.0387 0.0455 0.3889 3.9 8pv2:Cd, 8pv3:Cd, 8pv4:Cd, 8pv5:Cd, 8pv6:Cd, 8pv7:Cd, 8pv8:Cd, 8pvk:Cd, 8pvl:Cd
64 8kie:y 363 30 0.0203 0.0303 0.3667 5.4
65 7pd3:z 311 73 0.0406 0.0707 0.3014 5.8 8pk0:z, 8qsj:z
66 5oql:Z 639 126 0.0554 0.0469 0.2381 6.8
67 7o9k:C 255 66 0.0351 0.0745 0.2879 7.1 7o9m:C
68 2bs2:B 239 36 0.0258 0.0586 0.3889 8.2 2bs2:E, 2bs3:B, 2bs3:E, 2bs4:B, 2bs4:E, 1e7p:B, 1e7p:E, 1e7p:H, 1e7p:K, 1qlb:B, 1qlb:E
69 9bht:A 220 59 0.0387 0.0955 0.3559 9.4 9bht:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218