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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVN
RFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGI
LIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEES
RQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVV
ERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAG
FSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPET

The query sequence (length=447) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5eqg:A 447 447 1.0000 1.0000 1.0000 0.0 5eqh:A, 5eqi:A
2 7spt:A 470 447 0.6756 0.6426 0.6756 0.0 5c65:A, 5c65:B, 7crz:A, 7sps:A, 7sps:B, 4zw9:A, 4zwb:A, 4zwc:A, 4zwc:B
3 7wsm:A 464 451 0.6913 0.6659 0.6851 0.0 7wsn:A
4 8y65:A 467 447 0.3982 0.3812 0.3982 3.26e-115 8y66:A
5 4gby:A 475 467 0.2953 0.2779 0.2827 2.32e-47 4gbz:A, 4gc0:A
6 7aaq:A 487 461 0.2685 0.2464 0.2603 2.18e-40 7aar:A, 6h7d:A
7 9g11:A 476 458 0.2819 0.2647 0.2751 3.54e-40
8 6m20:B 478 450 0.2841 0.2657 0.2822 6.43e-39 6m20:A, 6m20:C, 6m20:D, 6m2l:A, 6m2l:B, 6rw3:A, 6rw3:B, 6rw3:C, 6rw3:D
9 8et9:A 517 219 0.1253 0.1083 0.2557 6.20e-09
10 8et7:A 532 300 0.1521 0.1278 0.2267 1.61e-08 8et8:A
11 7zha:A 487 326 0.1924 0.1766 0.2638 2.30e-08 7zh6:A
12 8jtz:A 530 311 0.1521 0.1283 0.2186 3.57e-08 8jtt:A
13 8bvt:A 508 333 0.1723 0.1516 0.2312 8.56e-05 8bvs:A, 8bw7:A, 8sdz:A
14 8bvt:A 508 107 0.0649 0.0571 0.2710 2.3 8bvs:A, 8bw7:A, 8sdz:A
15 8jlc:A 592 232 0.1320 0.0997 0.2543 9.77e-05 8jlh:A, 8jli:A, 8jli:B, 8js8:A, 8k77:A, 8uo9:A, 8yf1:B, 8yf1:A
16 8uo8:A 574 235 0.1320 0.1028 0.2511 1.12e-04
17 8sc2:A 453 166 0.0962 0.0949 0.2590 0.002 8jtv:A, 8ju0:A, 8sc3:A, 8sc6:A
18 9b1l:A 529 248 0.1409 0.1191 0.2540 0.008 9b1g:A, 9b1h:A, 9b1i:A, 9b1j:A, 9b1k:A, 9b1m:A, 9b1n:A, 9b1o:A
19 1z63:A 468 122 0.0694 0.0662 0.2541 0.052 1z63:B
20 7wtt:z 82 46 0.0358 0.1951 0.3478 0.063 7wts:z, 7wtu:z, 7wtw:z
21 3b3d:A 280 55 0.0336 0.0536 0.2727 2.7 3b3d:B, 3b3d:C
22 3fhd:A 456 53 0.0380 0.0373 0.3208 2.8 5hsw:A, 3pov:A
23 7pkq:b 241 81 0.0537 0.0996 0.2963 4.0
24 7v8i:D 229 34 0.0403 0.0786 0.5294 4.8 7arj:F, 7arj:D, 7ark:D, 7ark:F, 7arl:F, 7arl:D, 7mdy:D, 7mdy:C, 7v8i:F
25 8hcj:D 433 77 0.0380 0.0393 0.2208 4.8 8hcj:E, 8hcj:H, 8hcj:A, 8hcj:B, 8hcj:G, 8hcj:C, 8hcj:F
26 2rir:E 298 68 0.0447 0.0671 0.2941 5.2 2rir:A, 2rir:B, 2rir:C, 2rir:D, 2rir:F, 2rir:G, 2rir:H
27 4rn3:A 210 82 0.0604 0.1286 0.3293 6.4 4rn3:B
28 8pvr:B 509 83 0.0537 0.0472 0.2892 9.9 8pvr:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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