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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TGPILSGLDPRFERTLYAHVGKEGSWTLDYYLRHGGYETAKRVLKEKTPDEVIEEVKRSGLRGRGGAGFPTGLKWSFMPK
DDGKQHYLICNADESEPGSFKDRYILEDVPHLLIEGMILAGYAIRATVGYIYVRGEYRRAADRLEQAIKEARARGYLGKN
LFGTDFSFDLHVHRGAGAYICGEETALMNSLEGLRANPRLKPPFPAQSGLWGKPTTINNVETLASVVPIMERGADWFAQM
GTEQSKGMKLYQISGPVKRPGVYELPMGTTFRELIYEWAGGPLEPIQAIIPGGSSTPPLPFTEEVLDTPMSYEHLQAKGS
MLGTGGVILIPERVSMVDAMWNLTRFYAHESCGKCTPCREGVAGFMVNLFAKIGTGQGEEKDVENLEALLPLIEGRSFCP
LADAAVWPVKGSLRHFKDQYLALAREKRPVPRPSLWR

The query sequence (length=437) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4hea:1 437 437 1.0000 1.0000 1.0000 0.0 2fug:1, 2fug:A, 2fug:J, 2fug:S, 4hea:B, 6i0d:1, 6i0d:B, 6i1p:1, 6i1p:B, 3i9v:1, 3i9v:A, 3iam:1, 3iam:A, 3ias:1, 3ias:A, 3ias:J, 3ias:S, 3m9s:1, 3m9s:A, 6q8o:1, 6q8o:B, 6q8w:1, 6q8w:B, 6q8x:1, 6q8x:B, 6y11:1, 6y11:B, 2ybb:1, 6ziy:1, 6zjl:1, 6zjn:1, 6zjy:1
2 7p61:F 442 405 0.4554 0.4502 0.4914 8.27e-134 7awt:F, 7nyr:F, 7nyu:F, 7nyv:F, 7nz1:F, 7p62:F, 7p63:F, 7p64:F, 7p69:F, 7p7c:F, 7p7e:F, 7p7j:F, 7p7k:F, 7p7l:F, 7p7m:F, 7z7r:F, 7z7s:F, 7z7t:F, 7z7v:F, 7z80:F, 7z83:F, 7z84:F, 7zc5:F, 7zci:F
3 8e9h:F 436 408 0.4943 0.4954 0.5294 2.95e-132 8e9g:F, 8e9i:F
4 7t2r:B 425 417 0.4691 0.4824 0.4916 3.39e-132 7t2r:G, 7t30:B, 7t30:G
5 8gym:v1 442 409 0.4279 0.4231 0.4572 2.64e-127 8b6f:AD, 8bqs:AD, 8gym:V1, 8gzu:v1, 8gzu:V1, 7tgh:V1
6 7arc:F 430 377 0.4302 0.4372 0.4987 1.08e-124 7ard:F
7 7aqr:F 434 391 0.4325 0.4355 0.4834 4.35e-124 7a23:A, 7a24:A, 7ar7:F, 7ar8:F, 7arb:F, 8bed:F, 8bpx:F, 8bq5:F, 8bq6:F, 8e73:V1, 6x89:V1
8 8qby:F 421 397 0.4142 0.4299 0.4559 4.45e-124
9 8oh5:B 584 404 0.4531 0.3390 0.4901 2.35e-123 8oh5:E, 8oh5:H, 8oh5:K, 8oh9:B, 8oh9:E, 8oh9:H, 8oh9:K
10 7q4v:B 599 420 0.4668 0.3406 0.4857 1.45e-122 8a5e:B, 7q4v:F, 7q4w:B, 7q4w:F
11 8b9z:F 441 409 0.4211 0.4172 0.4499 1.95e-120 8ba0:F, 8esw:V1, 8esz:V1
12 7v2c:A 433 411 0.4394 0.4434 0.4672 9.54e-120 7ak5:F, 7ak6:F, 7b93:F, 8c2s:F, 8ca3:F, 8ca4:F, 8ca5:F, 7dgq:8, 7dgr:8, 7dgs:8, 7dgz:8, 7dh0:8, 7dkf:82, 6g2j:F, 6g72:F, 5gpn:c, 5gup:B, 8iao:F, 8iap:F, 8ib4:F, 8ib5:F, 8ib9:F, 8iba:F, 8ibd:F, 8ibe:F, 8ic2:F, 8ic3:F, 5lc5:F, 5ldw:F, 5ldx:F, 5lnk:1, 5o31:F, 8olt:F, 8om1:F, 7psa:F, 8pw5:1, 8pw6:1, 8pw7:1, 8q0a:F, 8q0f:F, 8q0j:F, 8q0m:F, 8q0o:F, 8q0q:F, 8q1p:F, 8q1u:F, 8q1y:F, 8q25:F, 8q45:F, 8q46:F, 8q47:F, 8q48:F, 8q49:F, 8q4a:F, 6q9d:V1, 6qa9:V1, 6qbx:V1, 6qc2:V1, 6qc3:V1, 6qc4:V1, 6qc5:V1, 6qc6:V1, 6qc7:V1, 6qc8:V1, 6qc9:V1, 6qca:V1, 6qcf:V1, 7qsd:F, 7qsk:F, 7qsl:F, 7qsm:F, 7qsn:F, 7qso:F, 7r41:F, 7r42:F, 7r43:F, 7r44:F, 7r45:F, 7r46:F, 7r47:F, 7r48:F, 7r4c:F, 7r4d:F, 7r4f:F, 7r4g:F, 8rgp:1, 8rgq:1, 8rgr:1, 8rgt:1, 8ud1:1F, 8ueo:1F, 8uep:1F, 8ueq:1F, 8uer:1F, 8ues:1F, 8uet:1F, 8ueu:1F, 8uev:1F, 8uew:1F, 8uex:1F, 8uey:1F, 8uez:1F, 8ugh:1F, 8ugi:1F, 8ugj:1F, 8ugn:1F, 8ugn:5F, 8ugr:1F, 8ugr:5F, 7v2d:A, 7v2e:A, 7v2f:A, 7v2h:A, 7v2k:A, 7v2r:A, 7v30:A, 7v31:A, 7v32:A, 7v33:A, 7v3m:A, 7vb7:A, 7vbn:A, 7vbz:A, 7vwj:A, 7vxp:A, 7vxu:A, 7vy8:A, 7vya:A, 7vyf:A, 7vyh:A, 7vyn:A, 7vz1:A, 7vzv:A, 7vzw:A, 7w00:A, 7w0h:A, 7w0r:A, 7w0y:A, 7w1o:A, 7w1p:A, 7w1t:A, 7w1u:A, 7w1v:A, 7w1z:A, 7w20:A, 7w2k:A, 7w2l:A, 7w2r:A, 7w2u:A, 7w2y:A, 7w31:A, 7w32:A, 7w35:A, 7w4c:A, 7w4d:A, 7w4e:A, 7w4f:A, 7w4g:A, 7w4j:A, 7w4k:A, 7w4l:A, 7w4m:A, 7w4n:A, 7w4q:A, 5xtb:A, 5xtd:A, 5xth:A, 5xti:A, 5xti:BA, 7zd6:1, 7zdh:1, 7zdj:1, 7zdm:1, 7zdp:1, 7zeb:1, 6zk9:1, 6zkc:1, 6zkd:1, 6zke:1, 6zkf:1, 6zkg:1, 6zkh:1, 6zki:1, 6zkj:1, 6zkk:1, 6zkl:1, 6zkm:1, 6zkn:1, 6zko:1, 6zkp:1, 6zkq:1, 6zkr:1, 6zks:1, 6zkt:1, 6zku:1, 6zkv:1, 6zr2:F, 6ztq:F
13 7b0n:F 460 418 0.4394 0.4174 0.4593 1.47e-119 6gcs:B, 7o6y:B, 7o71:B, 6rfq:B, 6rfr:B, 6rfs:B, 6y79:B, 6yj4:F
14 8iuf:V1 504 410 0.4302 0.3730 0.4585 2.30e-119 8j9h:V1, 8j9i:V1, 8j9j:V1
15 7zm7:B 456 406 0.4325 0.4145 0.4655 1.55e-117 7zmb:B, 7zmg:B
16 8a6t:B 630 417 0.4211 0.2921 0.4412 3.47e-117 8a6t:E, 8bew:B, 8bew:E
17 7p8n:B 613 433 0.4348 0.3100 0.4388 5.07e-117 7p5h:B, 7p5h:E, 7p5h:b, 7p5h:e, 7p8n:b, 7p91:b, 7p91:B, 7p92:B
18 9fdv:B 419 396 0.4325 0.4511 0.4773 2.11e-116 9fdj:B, 9fdj:D, 9fdk:B, 9fdk:D, 9fdv:D, 9fe0:B, 9fe0:D, 9fe5:B, 9fe5:D, 9fe7:B, 9fe7:D, 9fe8:B, 9fe8:D, 9fea:B, 9fea:D, 9fif:B, 9fif:D, 9fih:B, 9fih:D, 9fii:B, 9fii:D, 9fij:B, 9fij:D, 9fil:B, 9fil:D, 6hl2:B, 6hl2:D, 6hl3:B, 6hl3:D, 6hl4:B, 6hl4:D, 6hla:B, 6hla:D, 6hli:B, 6hli:D, 6hlj:B, 6hlj:D, 6hlm:B, 6hlm:D, 7q5y:C, 7q5y:I, 7q5y:O, 7q5y:U, 6q9c:B, 6q9c:D, 6q9g:B, 6q9g:D, 6q9j:B, 6q9j:D, 6q9k:B, 6q9k:D, 8qg1:B, 8qg1:D, 8qgw:B, 8qgw:D, 8qh4:B, 8qh4:D, 8qh7:B, 8qh7:D, 8qhk:B, 8qhk:D, 6r7p:B, 6r7p:D, 6saq:B, 6saq:D
19 6vw7:D 514 410 0.3936 0.3346 0.4195 2.63e-93 6vw7:B, 6vw8:B, 6vw8:D
20 6tg9:B 493 412 0.3638 0.3225 0.3859 5.92e-87 6tg9:F, 6tga:B, 6tga:F
21 5xfa:A 581 412 0.3707 0.2788 0.3932 1.16e-73 5xf9:A, 5xf9:E, 5xfa:E
22 7vw6:B 560 395 0.3455 0.2696 0.3823 3.10e-71 7e5z:B, 8j83:B, 7xqw:B
23 7zc6:C 435 322 0.1785 0.1793 0.2422 2.42e-12
24 4wz7:B 370 52 0.0435 0.0514 0.3654 0.18 6h8k:B
25 4wz7:B 370 58 0.0458 0.0541 0.3448 1.9 6h8k:B
26 8rbq:C 477 78 0.0481 0.0440 0.2692 0.59 8ahx:C, 8rb8:C, 8rb9:C, 8rbm:C
27 4tlx:A 415 94 0.0572 0.0602 0.2660 5.2 4tlx:B, 4tlx:C, 4tlx:D, 4tlz:A, 4tlz:B, 4tlz:C, 4tlz:D, 4tm0:A, 4tm0:B, 4tm0:C, 4tm0:D, 4tm1:A, 4tm1:B, 4tm1:C, 4tm1:D, 4tm3:A, 4tm3:B, 4tm3:C, 4tm3:D, 4tm4:A, 4tm4:B, 4tm4:C, 4tm4:D
28 5lb9:A 365 67 0.0572 0.0685 0.3731 5.6 1guf:A, 1guf:B, 5lbx:A, 5lbx:B, 1n9g:A, 1n9g:B, 1n9g:E, 4was:A, 4was:B, 4was:C
29 4grs:A 333 38 0.0297 0.0390 0.3421 6.0 4c1k:A, 4c1k:B, 4c1k:C, 4c1k:D, 4c1k:E, 4c1k:F, 4c1l:A, 4c1l:B, 4grs:C, 4grs:B, 4grs:D, 1zco:A, 1zco:B
30 2cfb:A 360 83 0.0549 0.0667 0.2892 6.8
31 6mfv:A 641 132 0.0732 0.0499 0.2424 7.0 6mfv:B, 6mfv:C, 6mfv:D
32 6dvh:A 394 44 0.0366 0.0406 0.3636 8.8 6dvh:B, 6dvh:C, 6dvh:D, 6dvh:E, 6dvh:F, 6dvi:A, 6dvi:B, 6dvi:C, 6dvi:E, 6dvi:F
33 3a9l:A 207 50 0.0458 0.0966 0.4000 9.0 3a9l:B
34 1qwg:A 251 87 0.0526 0.0916 0.2644 9.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218