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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TFQGKCTGFADKINLPNVRVNFVNYVPGGTNLSLPDNPTSCGTTSQVVSEDVCRIAMAVATSNSSEITLEAWLPQNYTGR
FLSTGNGGLSGCIQYYDLAYTSGLGFATVGANSGHNGTSGEPFYHHPEVLEDFVHRSVHTGVVVGKQLTKLFYEEGFKKS
YYLGCSTGGRQGFKSVQKYPNDFDGVVAGAPAFNMINLMSWSAHFYSITGPVGSDTYLSPDLWNITHKEILRQCDGIDGA
EDGIIEDPSLCSPVLEAIICKPGQNTTECLTGKQAHTVREIFSPLYGVNGTLLYPRMQPGSEVMASSIMYNGQPFQYSAD
WYRYVVYENPNWDATKFSVRDAAVALKQNPFNLQTWDADISSFRKAGGKVLTYHGLMDQLISSENSKLYYARVAETMNVP
PEELDEFYRFFQISGMAHCSGGDGAYGIGNQLVTYNDANPENNVLMAMVQWVEKGIAPETIRGAKFTNGTGSAVEYTRKH
CRYPRRNVYKGPGNYTDENAWQCV

The query sequence (length=504) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6g21:A 504 504 1.0000 1.0000 1.0000 0.0 6g21:B
2 3wmt:A 503 506 0.5913 0.5924 0.5889 0.0 3wmt:B
3 6fat:A 508 504 0.5258 0.5217 0.5258 0.0 8bhh:B, 8bhh:A, 6fat:B
4 6qz4:A 568 532 0.2758 0.2447 0.2613 1.17e-39 8ekg:A, 8ekg:B, 8ekg:C, 8ekg:E, 8ekg:D, 8ekg:F, 6jtt:A, 6jtt:B, 6jtt:C, 6jtu:A, 6jtu:B, 6jtu:C, 6qg9:A, 6qg9:B, 6qg9:C, 6qg9:D, 6qg9:E, 6qg9:F, 6qg9:G, 6qg9:H, 6qg9:I, 6qg9:J, 6qga:A, 6qga:B, 6qga:C, 6qga:D, 6qga:E, 6qga:F, 6qgb:A, 6qgb:B, 6qgb:C, 6qgb:D, 6qgb:E, 6qgb:F, 6qz1:A, 6qz2:A, 6qz2:B, 6qz2:C, 6qz2:D, 6qz2:E, 6qz2:F, 6qz2:G, 6qz2:H, 6qz2:I, 6qz2:J, 6qz3:A, 6qz4:B
5 7k4o:A 554 520 0.2698 0.2455 0.2615 3.62e-33
6 4q9d:B 519 58 0.0377 0.0366 0.3276 0.14 4q9d:A
7 5dua:A 445 69 0.0397 0.0449 0.2899 1.2 5du9:A, 5du9:B, 5dua:B
8 6qe2:A 257 55 0.0337 0.0661 0.3091 1.6 6qe2:B
9 8cnt:A 620 59 0.0377 0.0306 0.3220 2.7
10 7q50:A 170 73 0.0357 0.1059 0.2466 4.1 6cct:A, 6ccu:A, 6cd8:A, 6cd8:B, 6cd9:A, 6cdc:A, 6cdg:A, 7s12:A, 7slz:A, 7u3e:A, 7u3e:B, 7u3f:A, 7u3g:A, 7u3h:A, 7u3i:A, 7u3i:B, 7u3j:A, 7u3k:A, 7u3l:A, 8v1p:A, 6wzx:A, 6wzx:B, 6wzz:A
11 8em4:A 3818 45 0.0317 0.0042 0.3556 4.6 8em4:B
12 8em7:A 4378 45 0.0317 0.0037 0.3556 4.9 8em7:B, 8jut:A, 8jut:B, 8juu:B, 8juu:A, 8jx8:B, 8jx8:A, 8jx9:B, 8jxa:A, 8jxb:A, 8jxd:A, 8jxe:A, 8jxe:B, 8jxf:B, 8jxg:A, 8jxh:A, 8jxi:B
13 5fhz:F 449 130 0.0655 0.0735 0.2538 5.1
14 5tma:A 567 62 0.0377 0.0335 0.3065 8.1 3oe1:A, 3oe1:B, 3oe1:C, 3oe1:D, 5tma:B, 2wva:A, 2wva:B, 2wva:E, 2wva:F, 2wva:V, 2wva:Z, 2wva:X, 2wva:Y, 2wvg:A, 2wvg:B, 2wvg:E, 2wvg:F, 1zpd:A, 1zpd:B, 1zpd:E, 1zpd:F, 4zp1:A, 4zp1:B, 4zp1:C, 4zp1:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218