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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TFGCTDSPVRRERGQKAVFCGLTSIVWLHRKMQDAFFLVVGSRTCAHLLQAAAGVMIFAEPRFGTAVLEEQDLAGLADAH
KELDREVAKLLERRPDIRQLFLVGSCPSEVLKLDLDRAAERLSGLHAPHVRVYSYTGSGLDTTFTQGEDTCLAAMVPTLD
TTEAAELIVVGALPDVVEDQCLSLLTQLGVGPVRMLPARRSDIEPAVGPNTRFILAQPFLGETTGALERRGAKRIAAPFP
FGEEGTTLWLKAVADAYGVSAEKFEAVTAAPRARAKKAIAAHLETLTGKSLFMFPDSQLEIPLARFLARECGMKTTEIAT
PFLHKAIMAPDLALLPSNTALTEGQDLEAQLDRHEAINPDLTVCGLGLANPLEAKGHATKWAIELVFTPVHFYEQAGDLA
GLFSRPLRRRALLN

The query sequence (length=414) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3aek:A 415 414 1.0000 0.9976 1.0000 0.0 3aek:C, 3aeq:A, 3aeq:C, 3aer:A, 3aer:C, 3aes:A, 3aes:C, 3aet:A, 3aet:C, 3aeu:A, 3aeu:C
2 2ynm:C 417 410 0.5676 0.5635 0.5732 1.35e-174
3 2xdq:A 425 416 0.3720 0.3624 0.3702 5.22e-86
4 8oie:A 520 126 0.0797 0.0635 0.2619 0.002 8oie:F
5 8boq:A 515 117 0.0700 0.0563 0.2479 0.002 8boq:D
6 8boq:B 461 98 0.0531 0.0477 0.2245 0.010 8boq:E
7 8oie:C 456 97 0.0556 0.0504 0.2371 0.21 8oie:H, 8pbb:B, 8pbb:D
8 7adr:A 473 302 0.1256 0.1099 0.1722 1.6 7adr:D, 7ady:A, 7ady:D, 7aiz:A, 7aiz:D, 6fea:A, 6fea:D, 5n6y:A, 5n6y:D
9 9cp7:A 436 91 0.0652 0.0619 0.2967 2.7 9cp7:B, 9cp8:A, 9cp8:B, 9cp9:A, 9cp9:B, 8v35:A, 8v36:A, 8v37:A
10 3aer:D 421 102 0.0700 0.0689 0.2843 3.1 3aek:B, 3aek:D, 3aeq:B, 3aeq:D, 3aer:B, 3aes:B, 3aes:D, 3aet:B, 3aet:D, 3aeu:D
11 1fe5:A 118 46 0.0411 0.1441 0.3696 3.3 1dpy:A
12 7bss:A 816 39 0.0338 0.0172 0.3590 7.8 7bsu:A, 7bsv:A, 7bsw:A, 7vsg:A
13 8d8j:F 131 51 0.0338 0.1069 0.2745 7.9 8d8k:F, 8d8l:F, 5mrc:FF, 5mre:FF, 5mrf:FF, 8om2:F, 8om3:F, 8om4:F
14 6lkn:A 1064 46 0.0362 0.0141 0.3261 8.8 6lkn:E, 6lkn:I, 6lkn:M
15 7bsp:A 1028 46 0.0362 0.0146 0.3261 8.8 7bsq:A, 7vsh:A
16 2imc:B 405 67 0.0386 0.0395 0.2388 9.4 3dse:A, 4hev:A, 4hev:B, 2ima:A, 2ima:B, 2imb:A, 2imb:B, 2imc:A, 7ky2:A, 7ky2:B, 7kyh:A, 7kyh:B, 7kyh:C, 7kyh:D, 7n18:A, 7n18:B, 3nf3:A, 3qix:A, 3qix:B, 3qiy:A, 3qiz:A, 3qj0:A, 5v8p:A, 5v8p:B, 5v8r:A, 5v8r:B, 5v8u:A, 5v8u:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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