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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TEKLTDYVNPFVGTDGYGNVYPGAQIPFGGIQISPDTDSRFYDAASGYKYNHLTLMGFSLTHLSGTGIPDLGDFLFIPGT
GEMKLEPGTHEDPDQGYRSRYSHDKEWASPNYYAVELADYGVKAEMTSGVRSGMFRFTYPESDNAFIMIDMNHTLWQSCE
WSNLRMINDSTITGYKLVKGWGPERHVYFTATFSKKLTGLRFVQDKKPVIYNTSRFRSSYEAWGKNLMACISFDTKAGEE
VTVKTAISAVSTDGARNNMKELDGLTFNELRAKGEALWEKELGKYTLTADRKTKETFYTSAYHAALHPFIFQDSDGQFRG
LDKNIEKAEGFTNYTVFSLWDTYRALHPWFNLVQQEVNADIANSMLAHYDKSVEKMLPIWSFYGNETWCMIGYHAVSVLA
DMIVKEVKGFDYERAYEAMKTTAMNSNYDCLPEYREMGYVPFDKEAESVSKTLEYAYDDYCIAQAAKKLGKEDDYHYFLN
RALSYQTLIDPETKYMRGRDSKGDWRTPFTPVAYQGWGDITEGFTMQYTWYVPQDVQGYINEAGKELFRKRLDELFTVEL
PDDIPDIQGRIGAYWHGNEPCHHVAYLYNYLKEPWKCQKWIRTIVDRFYGNTPDALSGNDDCGQMSAWYMFNCIGFYPVA
PSSNIYNIGSPCAEAITVRMSNGKNIEMTADNWSPKNLYVKELYVNGKKYDKSYLTYDDIRDGVKLRFVMSGKPNYKRAV
SDEAVPPSISLPEKTMKYKSSIGFLEH

The query sequence (length=747) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6f92:A 760 755 0.9987 0.9816 0.9881 0.0 6f91:A, 6f91:B, 6f91:C, 6f91:D, 6f91:E, 6f91:F, 6f91:G, 6f91:H, 6f92:B, 6f92:C, 6f92:D
2 6f8z:A 715 731 0.3829 0.4000 0.3912 3.54e-176 6f8z:B, 6f8z:C, 6f90:A, 6f90:B, 6f90:C
3 7zgm:A 702 720 0.3762 0.4003 0.3903 5.60e-153
4 2wvz:B 742 765 0.3360 0.3383 0.3281 7.79e-118 2wvx:A, 2wvx:B, 2wvx:C, 2wvx:D, 2wvz:A, 2wvz:C, 2wvz:D, 2ww0:A, 2ww0:B, 2ww0:C, 2ww0:D, 2ww0:E, 2ww0:F, 2ww0:G, 2ww0:H, 2ww1:A, 2ww1:B, 2ww1:C, 2ww1:D, 2ww3:A, 2ww3:B, 2ww3:C, 2ww3:D, 2ww3:E, 2ww3:F, 2wzs:A, 2wzs:B, 2wzs:C, 2wzs:D, 2wzs:E, 2wzs:F, 2wzs:G, 2wzs:H
5 2ww2:B 737 767 0.3173 0.3216 0.3090 2.29e-106
6 7nsn:A 1371 799 0.3079 0.1678 0.2879 4.78e-71 7nsn:B
7 6dwo:A 712 725 0.2597 0.2725 0.2676 3.09e-63 6dwo:B, 6dwo:C, 6dwo:D, 7fe1:A, 7fe1:B, 7fe1:C, 7fe1:D, 7fe2:A, 7fe2:B, 7fe2:C, 7fe2:D
8 4aq0:A 765 775 0.2517 0.2458 0.2426 4.55e-49 4aq0:B, 2xsg:A, 2xsg:B
9 5swi:B 693 730 0.2463 0.2655 0.2521 1.61e-41 5swi:A, 5swi:C, 5swi:D
10 8fnv:A 770 136 0.0509 0.0494 0.2794 2.3 8fnv:B, 8fnv:C, 8fnv:D, 8fnv:E, 8fnv:F, 8fnv:G, 8fnv:H, 8fnv:I, 8fnv:J, 8fnv:K, 8fnv:L, 8fnw:A, 8fnw:B, 8fnw:C, 8fnw:D, 8fnw:E, 8fnw:F, 8fnw:G, 8fnw:H, 8fnw:I, 8fnw:J, 8fnw:K, 8fnw:L
11 4kqp:A 230 42 0.0228 0.0739 0.4048 2.4
12 7nry:X 283 71 0.0187 0.0495 0.1972 4.1 3fyj:X, 3fyk:X, 2jbp:K, 2jbp:L, 3ka0:A, 2p3g:X, 3r2y:A, 3r30:A
13 2pzy:C 307 71 0.0187 0.0456 0.1972 4.4 3a2c:A, 3a2c:B, 3a2c:C, 3a2c:D, 3a2c:E, 3a2c:F, 3a2c:G, 3a2c:H, 3a2c:I, 3a2c:J, 3a2c:K, 3a2c:L, 3fpm:A, 3gok:A, 3gok:B, 3gok:C, 3gok:D, 3gok:E, 3gok:F, 3gok:G, 3gok:H, 3gok:I, 3gok:J, 3gok:K, 3gok:L, 2jbo:A, 2jbp:A, 2jbp:B, 2jbp:C, 2jbp:D, 2jbp:E, 2jbp:F, 2jbp:G, 2jbp:H, 2jbp:I, 3kc3:A, 3kc3:B, 3kc3:C, 3kc3:D, 3kc3:E, 3kc3:F, 3kc3:H, 3kc3:I, 3kc3:J, 3kc3:K, 3kc3:L, 3kga:A, 3m2w:A, 3m42:A, 1nxk:A, 1nxk:B, 1nxk:C, 1nxk:D, 1ny3:A, 2pzy:A, 2pzy:B, 3r2b:A, 3r2b:B, 6t8x:A, 6t8x:B, 6t8x:C, 6t8x:D, 6t8x:E, 6t8x:F, 3wi6:A, 3wi6:B, 3wi6:C, 3wi6:D, 3wi6:E, 3wi6:F
14 8tn6:A 147 28 0.0161 0.0816 0.4286 5.5 8tn6:B, 8tn6:C, 8tnb:A, 8tnb:B, 8tnb:C, 8tnc:A, 8tnc:B, 8tnc:C, 8tnd:A, 8tnd:B, 8tnd:C
15 2k16:A 75 59 0.0228 0.2267 0.2881 9.9 5c13:A, 5c13:C, 5c13:E, 5c13:G, 2k17:A, 5wxg:A, 5wxh:C, 5wxh:A, 5xmy:A, 5xmy:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218