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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TDTTPPTITLPQEVIAYRGEEFEFFVETTDDSGRVNRVIVRNIEGADNSTYLDPNWIRYSTDNLSVPGNATPANPLRTRV
YGIVPINHGVGPGDRYTKYVRAEDAAGNITALVDKQSERFVLVIRPQTEKYTPQVPTLTYVQNANSLTQTDKDAVIAAVK
SANPNLPATSTYSVSENGTVTITYPDGSTDTIAAAQTVDTDRVAPVFVDEGRDYIFYRGEEGTAELHFYDNSGKITNVNF
AGDLAASSTYNTLLGLGFTFNTPNINNPNNATEQNPLVTTIRGTIPKSLPAGPGGKYTFKVRATDASGLTSEAKIFRIVF
ANQTDKYTPNNPGSLTGVLNPQQLSTSEKTAIEEKVRAANTGNLPNNVQYVVNNDGSVTVIYPDDTPASRSRDTITADRT
VQDLRPRNS

The query sequence (length=409) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6vs7:A 409 409 1.0000 1.0000 1.0000 0.0 6vs7:E, 6vt2:A, 6vt2:E, 6vu6:A, 6vu6:E
2 5eq2:A 201 202 0.2641 0.5373 0.5347 7.20e-62 5eq2:B, 5eq3:A, 5eq3:B, 5eq4:A, 5eq4:B, 5eq4:C, 5eq4:D, 5iiy:A, 5iiy:B, 5ij1:A, 5ij1:B, 5ij2:A, 5ij2:B, 5ij3:A, 5ij3:B, 5kiq:A, 5kiq:B
3 5eq2:A 201 196 0.1907 0.3881 0.3980 2.71e-28 5eq2:B, 5eq3:A, 5eq3:B, 5eq4:A, 5eq4:B, 5eq4:C, 5eq4:D, 5iiy:A, 5iiy:B, 5ij1:A, 5ij1:B, 5ij2:A, 5ij2:B, 5ij3:A, 5ij3:B, 5kiq:A, 5kiq:B
4 6efd:A 206 201 0.2592 0.5146 0.5274 1.64e-61 6efc:A, 7kmj:A, 8st6:A, 6x3k:A, 6x3q:A
5 6efd:A 206 205 0.1858 0.3689 0.3707 1.04e-16 6efc:A, 7kmj:A, 8st6:A, 6x3k:A, 6x3q:A
6 6efi:B 208 203 0.2494 0.4904 0.5025 2.72e-59 6efi:A
7 6efi:B 208 205 0.1932 0.3798 0.3854 1.09e-20 6efi:A
8 6eff:B 206 190 0.2421 0.4806 0.5211 1.47e-47 6eff:A, 6eff:C, 6eff:D
9 6eff:B 206 202 0.1809 0.3592 0.3663 6.38e-16 6eff:A, 6eff:C, 6eff:D
10 3qc5:X 352 219 0.1980 0.2301 0.3699 5.04e-26 6ef7:A, 6efa:A, 5iuc:A, 5iuc:B, 3qc6:X
11 6efb:A 201 215 0.1834 0.3731 0.3488 4.85e-23
12 6efb:A 201 134 0.1027 0.2090 0.3134 3.44e-05
13 8pxc:A 252 236 0.1443 0.2341 0.2500 1.98e-05
14 8pxc:A 252 144 0.0954 0.1548 0.2708 0.013
15 4dpv:Z 559 87 0.0489 0.0358 0.2299 1.2 1c8d:A, 1c8f:A, 1c8g:A, 1ijs:P, 1p5w:A, 4qyk:K, 4qyk:V, 4qyk:E, 4qyk:J, 4qyk:S, 4qyk:B, 4qyk:c, 4qyk:W, 4qyk:H, 4qyk:I, 4qyk:T, 4qyk:L, 4qyk:M, 4qyk:C, 4qyk:R, 4qyk:A, 4qyk:b, 4qyk:Y, 4qyk:d, 4qyk:F
16 3ftq:B 252 121 0.0660 0.1071 0.2231 1.7 3ftq:C, 3ftq:D, 2qnr:B, 6upa:A
17 5nxb:A 644 52 0.0391 0.0248 0.3077 2.2 4ccc:A, 4ccd:A, 4cce:A, 5nxb:B, 4ufh:A, 4ufi:A, 4ufj:A, 4ufk:A, 4ufl:A, 4ufm:A, 6y6s:A, 6y6t:A, 3zr5:A, 3zr6:A
18 7wfx:A 493 43 0.0367 0.0304 0.3488 3.9 7wfx:B, 7wg1:A, 7wg1:B, 7wg2:A, 7wg4:A
19 6yxx:EM 308 48 0.0342 0.0455 0.2917 4.2
20 6yxy:EM 330 48 0.0342 0.0424 0.2917 4.3
21 7am2:BT 300 48 0.0367 0.0500 0.3125 4.8
22 7w78:A 218 114 0.0709 0.1330 0.2544 5.3 7w79:A
23 2r5w:B 345 37 0.0244 0.0290 0.2703 6.6 2qjt:B, 2qjt:A, 2r5w:A
24 3e18:A 348 79 0.0587 0.0690 0.3038 8.7 3e18:B
25 6a0f:B 305 96 0.0636 0.0852 0.2708 9.9 6a0f:A, 6a0h:A, 6a0h:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218