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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TDKTLQQIDKLICSWLKQIDNVIPQLIMEMTTETKRHRFDLVTNVDKQIQQQFQQFLATYFPEHQLLAEEKSNAMITNEI
NHLWIMDPIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGIKMEEPPSLKLEDAIISFNA
QVMNLDTVQDLFDASFSYRLVGACGLDSMRVAKGQFGAHINTNPKPWDIAAQFLFAELLNLKMTTLDGKAIDHLKGAPFI
ISNKACHETVLKILNANGGYQKYR

The query sequence (length=264) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5eyg:B 265 264 0.9962 0.9925 0.9962 0.0 5eyg:A, 5eyh:A, 5eyh:B, 5f24:A, 5f24:B, 4g61:A, 4g61:B, 4i3e:A, 4i3e:B, 4i3y:A, 4i3y:B, 4i40:A, 4i40:B, 4ptk:A, 4ptk:B, 3ryd:A, 3ryd:C
2 5dw8:A 260 216 0.2576 0.2615 0.3148 4.40e-30 5dw8:B, 5j16:A, 5j16:B, 5j16:C, 5j16:D
3 2p3n:A 256 247 0.2538 0.2617 0.2713 1.07e-23 2p3n:B, 2p3n:C, 2p3n:D
4 6ib8:B 270 183 0.2008 0.1963 0.2896 5.83e-23 6ib7:A, 6ib8:A, 2qfl:A, 6tqn:T, 6tqn:S, 6tqo:T, 6tqo:S
5 8wdq:A 273 225 0.2235 0.2161 0.2622 3.81e-20 8wdq:B
6 2czi:A 259 191 0.2008 0.2046 0.2775 9.83e-18 2czh:B
7 6giu:A 275 247 0.2424 0.2327 0.2591 2.64e-17 4as4:A, 4as4:B, 1awb:A, 1awb:B, 6giu:B, 6gj0:A, 6gj0:B, 2hhm:A, 2hhm:B, 1ima:A, 1ima:B, 1imb:A, 1imb:B, 1imc:A, 1imc:B, 1imd:A, 1imd:B, 1ime:A, 1ime:B, 6zk0:AAA, 6zk0:BBB
8 2bji:A 274 237 0.2311 0.2226 0.2574 3.84e-16 2bji:B
9 3luz:B 234 194 0.2045 0.2308 0.2784 2.10e-15
10 5zon:A 256 225 0.2159 0.2227 0.2533 6.43e-14 5yht:A, 5yht:B, 5zon:B, 5zon:C, 5zon:D
11 4as5:A 274 222 0.2045 0.1971 0.2432 2.18e-13 4as5:B, 4as5:C, 4as5:D
12 3lv0:A 258 180 0.1818 0.1860 0.2667 1.00e-12 3luz:A, 3lv0:B
13 1dk4:A 252 165 0.1629 0.1706 0.2606 1.64e-09 1dk4:B, 1g0h:A, 1g0h:B, 1g0i:A, 1g0i:B
14 5eq9:B 260 108 0.1061 0.1077 0.2593 6.38e-09 5eq8:A, 5eq9:A, 5eq9:C, 5eq9:D, 5t3j:A
15 6b5z:A 252 171 0.1667 0.1746 0.2573 4.16e-05 6b5z:B, 6b60:A, 6b60:B, 6b61:A, 6b61:B, 6b62:A, 6b62:B, 6b63:A, 6b63:B, 6b64:A, 6b64:B, 6b65:A, 6b65:B, 6b66:A, 6b66:B, 1lbx:A, 1lbx:B, 1lby:A, 1lby:B, 1lbz:A, 1lbz:B
16 4hxv:A 317 271 0.2159 0.1798 0.2103 0.002 4o7i:A
17 5djj:A 257 211 0.1591 0.1634 0.1991 0.004 5djg:A, 5djh:A, 5dji:A, 5djk:A
18 4qxd:B 289 99 0.0985 0.0900 0.2626 0.032 4qxd:A
19 8f9y:A 352 36 0.0492 0.0369 0.3611 0.11
20 1k9y:A 354 73 0.0758 0.0565 0.2740 0.48 1k9z:A, 1ka0:A, 1ka1:A, 1qgx:A
21 4qr8:A 441 73 0.0758 0.0454 0.2740 6.5 4qr8:B
22 5mlt:A 454 54 0.0568 0.0330 0.2778 7.6 5swa:A, 5swa:B, 5swb:A, 5swb:C, 5swb:D, 5swb:G
23 3cx5:P 185 74 0.0795 0.1135 0.2838 8.4 3cx5:E, 3cxh:P, 3cxh:E, 8e7s:C, 8e7s:c, 8ec0:C, 8ec0:c, 1ezv:E, 6giq:E, 6giq:P, 6hu9:E, 6hu9:P, 2ibz:E, 1kb9:E, 1kyo:E, 1kyo:P, 1p84:E, 4pd4:E, 6t0b:E, 6t0b:P, 6t15:E, 6t15:P, 6ymx:E, 6ymx:P
24 3qvq:A 251 116 0.1098 0.1155 0.2500 9.2 3qvq:B, 3qvq:C, 3qvq:D
25 3zok:A 365 45 0.0492 0.0356 0.2889 9.7 3zok:B, 3zok:C, 3zok:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218