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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TDISACSINIFYSTLGGSTQKFAEHVADRIRSSLQTELVEILNLDYIDLDEYFSKGNSNTVYLVLLPSYAIESSIDYFLS
ALQTTIDDFRIVARPLEKLRGFAVLGFGDFEQYAGDLFCYQAIAADQRLAKLGAQRIAPLGVVNVKLEKAQVYEAMEAWT
DLFLQYAKE

The query sequence (length=169) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6puq:A 171 168 0.9941 0.9825 1.0000 9.54e-123 6pup:A
2 1czh:A 169 134 0.2012 0.2012 0.2537 0.20 1czk:A, 1czl:A, 1czn:A, 1czo:A, 1czr:A, 1czu:A, 1d03:A, 1d04:A, 6kif:P, 6kif:X, 6kif:p, 1ofv:A
3 6j79:A 816 140 0.2367 0.0490 0.2857 0.24 1amo:A, 1amo:B, 1b1c:A, 1dve:A, 1dvg:A, 1dvg:B, 2dy5:A, 2e7e:A, 5emn:A, 5emn:B, 3es9:A, 3es9:B, 3es9:C, 5fa6:A, 5fa6:B, 4g7l:A, 4g7p:A, 4g7t:A, 4g7u:A, 4g8p:A, 4g8u:A, 4g8w:A, 4g98:A, 4g99:A, 3i9t:A, 3i9u:A, 1ivj:A, 1ix3:A, 1ix4:A, 1j02:A, 1j2c:A, 6j79:B, 6j7a:A, 6j7a:B, 6j7i:A, 6j7i:B, 1j9z:A, 1j9z:B, 1ja0:A, 1ja0:B, 1ja1:A, 1ja1:B, 7l18:AAA, 7l18:BBB, 4mec:A, 4mec:B, 4mec:C, 4mec:D, 4mec:E, 6njr:A, 6njr:B, 3ojw:A, 3ojx:A, 3qe2:A, 3qe2:B, 3qfc:A, 3qfc:B, 3qfr:A, 3qfr:B, 1ubb:A, 1ulx:A, 5urd:A, 5urd:B, 5ure:A, 5ure:B, 5urg:A, 5urg:B, 5urh:A, 5urh:B, 5uri:A, 5uri:B, 1vgi:A, 3wkt:A, 3wkt:B, 3wkt:C, 3wkt:D, 4y7c:A, 4y7c:B, 4y9r:A, 4y9r:B, 4y9u:A, 4y9u:B, 4yaf:A, 4yaf:B, 4yal:A, 4yal:B, 4yao:A, 4yao:B, 4yau:A, 4yau:B, 4yaw:A, 4yaw:B, 2zvu:A
4 4a2i:D 205 64 0.1065 0.0878 0.2812 0.55 8a3l:D, 7abz:i, 7ac7:i, 7acj:i, 7acr:i, 4adv:D, 5afi:d, 7afi:D, 7afl:D, 7afo:D, 8akn:E, 8am9:E, 6awb:G, 6awc:G, 6awd:G, 9ax7:D, 9ax8:d, 8aye:D, 8b0x:D, 7b5k:d, 8b7y:F, 8bf7:h, 8bge:h, 8bgh:h, 8bh4:h, 8bhj:h, 8bhl:h, 8bhn:h, 8bhp:h, 8bil:h, 8bim:h, 7bod:D, 7boe:D, 7bof:D, 7bog:D, 7boh:D, 7boi:D, 6bu8:D, 6by1:AD, 6by1:BD, 6c4i:d, 8cai:D, 8cep:D, 8cgj:D, 8cgr:D, 8cgu:D, 9cg5:D, 9cg6:D, 9cg7:D, 7cpj:d, 7d6z:k, 7d80:E, 6dnc:QA, 8eiu:D, 8ekc:d, 8emm:D, 6enf:d, 6enj:d, 6enu:d, 8eyq:D, 8eyt:D, 9fbv:D, 8fiz:AI, 8fto:D, 8fzd:d, 8fze:d, 8fzf:d, 8fzg:d, 8fzh:d, 8fzi:d, 8fzj:d, 8g2u:c, 8g31:c, 8g34:c, 8g38:c, 8g6w:D, 8g7p:d, 8g7q:d, 8g7r:d, 8g7s:d, 8ghu:d, 6gwt:d, 6gxm:d, 6gxn:d, 6gxo:d, 6gxp:d, 6h4n:d, 5h5u:k, 6h58:d, 6h58:dd, 6hrm:i, 8hsp:D, 8htz:D, 8hu1:D, 6i7v:AD, 6i7v:BD, 8ifb:D, 8ifc:D, 5iqr:i, 5it8:AD, 5it8:BD, 5j5b:AD, 5j5b:BD, 5j7l:AD, 5j7l:BD, 5j88:AD, 5j88:BD, 5j8a:AD, 5j8a:BD, 3j9y:d, 3j9z:SD, 5j91:AD, 5j91:BD, 3ja1:SD, 3jbu:D, 3jbv:D, 3jcd:d, 3jce:d, 3jcj:l, 3jcn:g, 5jc9:AD, 5jc9:BD, 7jss:I, 7jsw:I, 7jsz:I, 8jsg:l, 8jsh:l, 5jte:AD, 7jt1:I, 7jt2:I, 7jt3:I, 5ju8:AD, 7k00:D, 8k3o:D, 8k4e:D, 7k50:I, 7k51:I, 7k52:I, 7k53:I, 7k54:I, 7k55:I, 5kcr:1d, 5kcs:1d, 5kps:9, 5kpv:8, 5kpw:8, 5kpx:8, 5l3p:d, 6lkq:C, 7lv0:I, 5lza:d, 5lzb:d, 5lzc:d, 5lzd:d, 5lze:d, 5lzf:d, 7m5d:i, 5mdv:i, 5mdw:i, 5mdy:i, 5mdz:i, 5me0:D, 5me1:D, 5mgp:d, 5my1:D, 7n1p:SD, 7n2c:SD, 7n2u:SD, 7n2v:SD, 7n30:SD, 7n31:SD, 7nar:D, 7nas:D, 7nat:D, 7nau:D, 7nav:D, 7nax:D, 7nbu:D, 5no2:D, 5no3:D, 5no4:D, 5np6:G, 6nqb:D, 7nso:d, 7nsp:d, 7nsq:d, 5nwy:3, 7nwt:i, 7nww:h, 7o19:AD, 7o1a:AD, 7o1c:AD, 5o2r:d, 7o5h:D, 6o7k:l, 6o9j:d, 6o9k:d, 7oe0:D, 7oe1:D, 6ofx:I, 6og7:I, 6ogf:I, 6ogg:I, 6ogi:I, 7oi0:D, 7oif:h, 7oig:h, 7oii:h, 7oiz:D, 7oj0:D, 6om6:i, 6ore:i, 6orl:i, 6osk:i, 6osq:i, 6ost:i, 6ot3:i, 7ot5:h, 7otc:d, 6ouo:i, 8p16:i, 8p17:i, 8p18:i, 7p3k:D, 8peg:D, 8phj:D, 7pjs:d, 7pjt:d, 7pju:d, 7pjv:d, 7pjw:d, 7pjx:d, 7pjy:d, 7pjz:d, 8pkl:D, 8pva:D, 7q4k:AD, 8q4f:D, 6q97:i, 6q98:i, 6q9a:i, 7qg8:3, 7qgh:3, 7qgn:3, 7qgr:3, 8qk7:i, 8qoa:D, 8r3v:D1, 8r3v:D2, 8r6c:D, 8r8m:D, 8rcl:D1, 8rcl:D2, 8rcm:D1, 8rcm:D2, 8rcs:D1, 8rcs:D2, 8rct:D1, 8rct:D2, 7s1g:F, 7s1h:F, 7s1i:F, 7s1j:F, 7s1k:F, 7sa4:i, 7ss9:I, 7ssd:I, 7ssl:I, 7ssn:I, 7sso:I, 7ssw:I, 7st2:I, 7st6:I, 7st7:I, 8syl:d, 6szs:d, 8t5d:c, 8t5h:c, 6tbv:S041, 6tc3:S041, 7tos:S04, 6tqo:C, 4u1u:AD, 4u1u:CD, 4u1v:AD, 4u1v:CD, 4u20:AD, 4u20:CD, 4u24:AD, 4u24:CD, 4u25:AD, 4u25:CD, 4u26:AD, 4u26:CD, 4u27:AD, 4u27:CD, 5u4i:d, 5u4j:d, 5u9f:D, 5u9g:D, 7ug7:SD, 7uph:Y, 8upo:J, 8upr:J, 8uql:J, 8uqm:J, 8uqp:J, 8ur0:J, 8urh:J, 8uri:J, 8urx:J, 8ury:J, 5uyk:D, 5uyl:D, 5uym:D, 5uyn:D, 5uyp:D, 5uyq:D, 5uz4:D, 4v4h:AD, 4v4h:CD, 4v4q:AD, 4v4q:CD, 4v4v:AD, 4v4w:AD, 4v50:AD, 4v50:CD, 4v52:AD, 4v52:CD, 4v53:AD, 4v53:CD, 4v54:AD, 4v54:CD, 4v55:AD, 4v55:CD, 4v56:AD, 4v56:CD, 4v57:AD, 4v57:CD, 4v5b:BD, 4v5b:DD, 4v5h:AD, 4v5y:AD, 4v5y:CD, 4v64:AD, 4v64:CD, 4v65:AR, 4v66:AR, 4v69:AD, 4v6c:AD, 4v6c:CD, 4v6d:AD, 4v6d:CD, 4v6e:AD, 4v6e:CD, 4v6k:BH, 4v6l:AH, 4v6m:AD, 4v6n:BG, 4v6o:AG, 4v6p:AG, 4v6q:AG, 4v6r:AG, 4v6s:BF, 4v6t:AD, 4v6v:AD, 4v6y:AD, 4v6z:AD, 4v70:AD, 4v71:AD, 4v72:AD, 4v73:AD, 4v74:AD, 4v75:AD, 4v76:AD, 4v77:AD, 4v78:AD, 4v79:AD, 4v7a:AD, 4v7b:AD, 4v7c:AD, 4v7d:BD, 4v7i:BD, 4v7s:AD, 4v7s:CD, 4v7t:AD, 4v7t:CD, 4v7u:AD, 4v7u:CD, 4v7v:AD, 4v7v:CD, 4v85:AD, 4v89:AD, 4v9c:AD, 4v9c:CD, 4v9d:AD, 4v9d:BD, 4v9o:BD, 4v9o:DD, 4v9o:FD, 4v9o:HD, 4v9p:BD, 4v9p:DD, 4v9p:FD, 4v9p:HD, 8vs9:S04, 8vsa:S04, 6vu3:J, 6vwl:c, 6vwm:c, 6vwn:c, 6vyq:J, 6vyr:J, 6vys:J, 6vyt:J, 6vyu:J, 6vyw:J, 6vyx:J, 6vyy:J, 6vyz:J, 6vz2:J, 6vz3:J, 6vz5:J, 6vz7:J, 6vzj:J, 6w6k:D, 6w77:D, 6w7m:D, 6w7n:D, 6w7w:C, 5wdt:d, 6wd0:I, 6wd1:I, 6wd2:I, 6wd3:I, 6wd4:I, 6wd5:I, 6wd6:I, 6wd7:I, 6wd8:I, 6wd9:I, 6wda:I, 6wdb:I, 6wdc:I, 6wdd:I, 6wde:I, 6wdf:I, 6wdg:I, 6wdh:I, 6wdi:I, 6wdj:I, 6wdk:I, 6wdl:I, 6wdm:I, 5we4:d, 5we6:d, 4wf1:AD, 4wf1:CD, 5wf0:d, 5wfk:d, 5wfs:d, 6wnv:I, 6wnw:I, 4woi:AD, 4woi:DD, 4www:XD, 4www:QD, 6x6t:J, 6x7f:J, 6x7k:J, 6x9q:J, 6xdq:J, 6xdr:J, 6xe0:C, 6xgf:J, 6xii:J, 6xij:J, 6xza:D1, 6xzb:D1, 6y69:d, 7y7c:D, 7y7d:D, 7y7e:D, 7y7f:D, 7y7g:D, 7y7h:D, 4ybb:AD, 4ybb:BD, 2ykr:D, 6ysr:d, 6yss:d, 6yst:d, 6ysu:d, 6ztj:AD, 6ztl:AD, 6ztm:AD, 6ztn:AD, 6zto:AD, 6ztp:AD, 7zta:S041, 6zu1:AD
5 8k1o:B 215 83 0.1302 0.1023 0.2651 0.98 8k1o:C, 8k1p:B, 8k1p:C
6 6efv:A 530 130 0.1953 0.0623 0.2538 1.2 1ddg:A, 1ddg:B, 1ddi:A, 1ykg:A
7 3hr4:A 189 40 0.0947 0.0847 0.4000 2.2 3hr4:C, 3hr4:E, 3hr4:G
8 7tj9:A 1111 40 0.1065 0.0162 0.4500 2.6
9 2fcr:A 173 139 0.2071 0.2023 0.2518 3.2
10 8uyh:A 375 39 0.0828 0.0373 0.3590 3.9 8uyh:B, 8uyi:A, 8uyi:B
11 6fsg:A 147 35 0.0533 0.0612 0.2571 4.2 6fsi:A, 6ft1:A
12 6w1s:I 1077 40 0.0947 0.0149 0.4000 5.1
13 7jpp:E 406 59 0.0947 0.0394 0.2712 5.5 7jpo:E, 7jpq:E, 7jpr:E, 5uj7:E, 5uj7:F
14 7jps:E 386 59 0.0947 0.0415 0.2712 5.9 7cte:E, 7ctf:E, 7ctg:E
15 5ujm:E 357 80 0.1065 0.0504 0.2250 6.1
16 4w97:A 196 56 0.1006 0.0867 0.3036 7.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218