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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TDIRSETAELRAELVERVHKFGPVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLETDVRTMSEVAKVLSHY
CPSTSWVVNNVNGSNLLASKFPRAALDEVFGDAPGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWAILVAREV
DADGEPVGGLSMLVPARDLTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLGLPPLFRTAAIAAMA
VVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSE
LLRIRGDVGQAVSLVTTALDELLWAHGAASFAESNPLQRYWRDANTAARHAMLNVHVGHELYGGSFFGLDPIVPSL

The query sequence (length=396) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5mr6:A 396 396 1.0000 1.0000 1.0000 0.0 5lvw:A, 5mr6:D, 5mr6:B, 5mr6:C, 5mr6:E, 5mr6:H, 5mr6:F, 5mr6:G, 5mr6:I, 5mr6:L, 5mr6:J, 5mr6:K, 5mr6:M, 5mr6:P, 5mr6:N, 5mr6:O, 5mr6:Q, 5mr6:R, 5mr6:S, 5mr6:T, 5mr6:U, 5mr6:V, 5mr6:W, 5mr6:X
2 2rfq:A 388 404 0.2929 0.2990 0.2871 2.77e-45 2rfq:B, 2rfq:C, 2rfq:D
3 2jbs:D 400 392 0.2525 0.2500 0.2551 4.78e-34 2jbs:A, 2jbs:B, 2jbs:C, 2jbt:A, 2jbt:D, 2jbt:B, 2jbt:C
4 5z8t:A 395 241 0.1869 0.1873 0.3071 8.98e-18 5z8t:B, 5z8t:C
5 7f74:A 371 359 0.2652 0.2830 0.2925 2.15e-17 7f72:A, 7f74:B, 7f74:C, 7f74:D
6 2d29:A 386 364 0.2071 0.2124 0.2253 1.97e-04 2d29:B
7 4zyj:D 392 198 0.1364 0.1378 0.2727 5.34e-04 4zyj:A, 4zyj:B, 4zyj:C
8 5xdc:B 402 372 0.2146 0.2114 0.2285 0.006 5xdb:A, 5xdb:B, 5xdb:C, 5xdb:D, 5xdc:A, 5xdc:C, 5xdc:D, 5xdd:A, 5xdd:B, 5xdd:C, 5xdd:D, 5xde:A, 5xde:B, 5xde:C, 5xde:D, 5xdg:A, 5xdg:B, 5xdg:C, 5xdg:D
9 3gqt:C 385 85 0.0657 0.0675 0.3059 0.019 3d6b:C, 3eon:C, 3gnc:A, 3gnc:B, 3gnc:C, 3gnc:D, 3gqt:A, 3gqt:B
10 7wrr:A 650 81 0.0682 0.0415 0.3333 0.065 7wrr:B, 7wrr:C, 7wrr:D, 7wrt:A, 7wrt:B, 7wrt:C, 7wrt:D
11 4kcf:A 407 216 0.1389 0.1351 0.2546 0.096 3m9v:A
12 2z1q:B 549 191 0.1111 0.0801 0.2304 0.30 2z1q:A
13 2pg0:A 380 104 0.0758 0.0789 0.2885 0.43 2pg0:B
14 7skh:B 220 124 0.0859 0.1545 0.2742 0.49 7skh:A
15 5ol2:F 378 214 0.1212 0.1270 0.2243 1.5 5ol2:C
16 2ix6:A 416 87 0.0480 0.0457 0.2184 2.1 2ix5:A, 2ix5:B, 2ix5:C, 2ix5:D, 2ix6:C, 2ix6:F, 2ix6:B, 2ix6:E, 2ix6:D
17 8phe:A 551 379 0.2045 0.1470 0.2137 2.7 8phe:B, 8phf:A, 8phf:B
18 7y0a:C 387 354 0.1944 0.1990 0.2175 3.9 1jqi:A, 1jqi:B, 8sgs:A, 8sgs:B, 8sgs:C, 8sgs:D, 2vig:A, 2vig:B, 2vig:C, 2vig:D, 2vig:E, 2vig:F, 2vig:G, 2vig:H, 7y0a:A, 7y0a:B, 7y0a:D, 7y0b:A, 7y0b:B, 7y0b:C, 7y0b:D
19 7szv:A 372 205 0.1313 0.1398 0.2537 5.0 7szv:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218