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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TCPFYKKIPGTGFTVDAFQYGVVEGCTAYFLTHFHSDHYAGLSKHFTFPVYCSEITGNLLKNKLHVQEQYIHPLPLDTEC
IVNGVKVVLLDANHCPGAVMILFYLPNGTVILHTGDFRADPSMERSLLADQKVHMLYLDTTYCSPEYTFPSQQEVIRFAI
NTAFEAVTLNPHALVVCGTYSIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEINSLITTDMCSSLVHLLPMMQINF
KGLQSHLKKCGGKYNQILAFRPTGWTVIPQTKGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGTWKSRSTMEK
YFREWKLEAGY

The query sequence (length=331) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8c8b:A 341 341 1.0000 0.9707 0.9707 0.0 5ahr:A, 4b87:A, 8c8d:A, 8c8s:A, 8cew:A, 8cf0:A, 8cg9:A, 5nzw:A, 5nzx:A, 5nzy:A, 5q1j:A, 5q1k:A, 5q1l:A, 5q1m:A, 5q1n:A, 5q1o:A, 5q1p:A, 5q1q:A, 5q1r:A, 5q1s:A, 5q1t:A, 5q1u:A, 5q1v:A, 5q1w:A, 5q1x:A, 5q1y:A, 5q1z:A, 5q20:A, 5q22:A, 5q23:A, 5q24:A, 5q25:A, 5q26:A, 5q27:A, 5q28:A, 5q29:A
2 7a1f:L 335 314 0.3384 0.3343 0.3567 1.12e-48 7a1f:A, 5aho:A
3 7sgl:D 406 347 0.3112 0.2537 0.2968 1.15e-21 7abs:A, 7af1:A, 7afs:A, 7afu:A, 7agi:A, 7apv:A, 6tt5:AAA, 6wnl:A, 6wnl:B, 6wo0:A
4 5a0t:A 454 343 0.2326 0.1696 0.2245 1.75e-04 5a0t:B, 5a0v:A, 5a0v:B
5 3zq4:A 550 143 0.1178 0.0709 0.2727 2.52e-04 3zq4:C, 3zq4:D, 3zq4:E
6 7wnu:B 554 148 0.1420 0.0848 0.3176 5.73e-04 7wnt:A, 7wnu:A
7 3t3o:A 553 159 0.1269 0.0759 0.2642 6.65e-04 3bk1:A, 3bk2:A, 3t3n:A
8 6k6s:A 443 145 0.1178 0.0880 0.2690 0.003 6k6s:B
9 4xww:A 545 150 0.1269 0.0771 0.2800 0.018 4xwt:A, 4xwt:B, 4xww:B
10 6r79:A 220 41 0.0514 0.0773 0.4146 0.054 6r73:A, 6r73:B, 6r78:A, 6r78:B, 6r79:D, 6r79:B, 6r79:C, 6rzr:A, 6rzr:B, 6rzs:A, 6rzs:B, 6s0h:A, 6s0h:B, 4ubq:A, 6yi4:AAA, 6yi4:BBB, 6yi4:CCC
11 6jka:C 228 83 0.0695 0.1009 0.2771 0.16 4c1f:A, 4c1f:B, 4c1g:A, 4c1g:B, 1dd6:A, 1dd6:B, 1ddk:A, 2doo:A, 2doo:B, 7dtm:A, 7dtm:B, 7dtm:C, 7dtm:D, 7dtn:A, 7dtn:B, 7dtn:C, 7dtn:D, 5ev6:A, 5ev6:B, 5ev6:C, 5ev6:D, 5ev8:A, 5ev8:C, 5ev8:B, 5ev8:D, 5ewa:A, 5ewa:B, 5ewa:C, 5ewa:D, 4f6h:A, 4f6z:A, 5hh4:A, 5hh4:B, 5hh4:C, 5hh4:D, 8hyb:A, 8hyb:B, 8hyb:C, 8hyb:D, 8jao:A, 8jao:B, 6jed:A, 1jje:A, 1jje:B, 1jjt:A, 1jjt:B, 6jka:A, 6jka:B, 6jka:D, 6lbl:A, 4uam:A, 4uam:B, 4uam:C, 4uam:D, 1vgn:A, 1vgn:B, 1wuo:A, 1wuo:B, 1wuo:C, 1wuo:D, 1wup:A, 1wup:B, 1wup:C, 1wup:D, 3wxc:A, 3wxc:B, 7wzu:A, 7wzu:B, 7wzu:C, 7wzu:D, 7xhw:A, 7xhw:B, 7xhw:C, 7xhw:D, 7xhx:A, 7xhx:B, 7xhx:C, 7xhx:D, 8y0s:A, 8y0s:B, 8y0s:C, 8y0s:D, 5y5b:A, 7yh9:A, 7yh9:B, 7yh9:C, 7yh9:F, 7yh9:D, 7yh9:E, 7yha:A, 7yha:B, 7yha:C, 7yha:D, 8z5l:A, 8z5l:B, 8z5l:C, 8z5l:D, 6zyr:A, 6zyr:B, 6zyr:C, 6zyr:D, 6zys:A, 6zys:B, 6zys:C, 6zys:D
12 6l3s:A 218 40 0.0483 0.0734 0.4000 0.37 6l3s:B
13 8fn0:B 212 59 0.0514 0.0802 0.2881 0.90
14 5b3r:B 219 38 0.0483 0.0731 0.4211 1.6 5b3r:A
15 4ojv:A 363 23 0.0363 0.0331 0.5217 1.8 4ojx:A
16 1e5e:A 394 75 0.0604 0.0508 0.2667 2.7 1e5e:B, 1e5f:A, 1e5f:B
17 5min:B 453 147 0.0997 0.0728 0.2245 3.6 1c9u:A, 1c9u:B, 1cq1:A, 1cq1:B, 1cru:A, 1cru:B, 5min:A, 1qbi:A, 1qbi:B, 8re0:A, 8re0:B, 8rfk:A, 8rfk:B, 8rg1:A, 8rg1:B
18 7qv7:A 174 85 0.0544 0.1034 0.2118 3.8 7qv7:G
19 4xeb:A 430 94 0.0755 0.0581 0.2660 4.5
20 3fm2:A 134 55 0.0483 0.1194 0.2909 6.3 3fm2:B
21 1x9p:A 460 62 0.0514 0.0370 0.2742 6.7 2c9f:A, 2c9f:B, 2c9f:C, 2c9f:D, 2c9f:E, 3izo:A, 3izo:B, 3izo:C, 3izo:D, 3izo:E, 4v4u:A, 4v4u:B, 4v4u:C, 4v4u:D, 4v4u:E, 1x9t:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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