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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TARLLSRSDWGARLPKSVEHFQGPAPYVIIHHSYMPAVCYSTPDCMKSMRDMQDFHQLERGWNDIGFSFGIGGDGMIYTG
RGFNVIGAHAPKYNDKSVGIVLIGDWRTELPPKQMLDAAKNLIAFGVFKGYIDPAYKLLGHRQVRDTECPGGRLFAEISS
WPHFTHINDTEG

The query sequence (length=172) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1oht:A 173 172 0.9942 0.9884 0.9942 3.89e-130 7nsx:AAA, 7nsz:AAA, 7nt0:AAA, 7nt0:BBB
2 4z8i:A 224 162 0.3837 0.2946 0.4074 5.94e-41
3 2cb3:C 173 167 0.4070 0.4046 0.4192 1.18e-40 2cb3:A, 2cb3:B, 2cb3:D
4 3cg9:A 171 162 0.3488 0.3509 0.3704 4.38e-37 6a89:B, 6a89:A, 6a89:D, 3cg9:B, 3cxa:A, 3cxa:B, 7dy5:C, 5e0b:C, 4fnn:A, 4fnn:B, 4fnn:D, 4gf9:D, 4gf9:C, 3ng4:C, 3ng4:D, 3nno:D, 3nw3:D, 3o4k:A, 3o4k:C, 3o4k:D, 3ogx:C, 3ogx:A, 4opp:A, 4opp:B, 4opp:D, 4opp:C, 4orv:D, 4oug:C, 4oug:D, 4q8s:A, 4q8s:C, 4q8s:D, 4q9e:D, 3qv4:C, 3rt4:C, 3rt4:D, 3t2v:B, 3t2v:D, 3t39:D, 3tru:D, 3usx:B, 7xfw:C, 7xfx:C, 7xfy:C, 7xfy:D, 7xu8:A, 7xu8:B
5 2xz4:A 165 163 0.3663 0.3818 0.3865 1.81e-35
6 2aph:A 165 164 0.3663 0.3818 0.3841 2.43e-35 2aph:B, 1sk4:A, 1twq:A
7 2f2l:X 166 164 0.3605 0.3735 0.3780 4.39e-35
8 2eax:C 164 163 0.3721 0.3902 0.3926 2.70e-32
9 2f2l:A 167 167 0.2733 0.2814 0.2814 5.25e-17
10 6srt:A 152 155 0.3023 0.3421 0.3355 1.38e-16 6ssc:A
11 1lba:A 146 120 0.2035 0.2397 0.2917 5.58e-10
12 6fhg:A 156 138 0.2267 0.2500 0.2826 9.73e-09 6fhg:B
13 6su5:A 154 143 0.2326 0.2597 0.2797 1.17e-08
14 7f5i:A 153 125 0.2093 0.2353 0.2880 1.90e-08
15 3e27:C 189 29 0.0640 0.0582 0.3793 2.3 3e27:A, 3e27:B, 3e27:D, 3hfj:A, 3hfj:B, 3mla:A, 3mla:B, 3mlb:A, 3mlb:B, 3mmx:B, 3mmx:C, 3mmx:A, 3mmx:D, 2qtn:B, 2qtr:A, 2qtr:B, 2qtr:C
16 7xqm:B 253 36 0.0756 0.0514 0.3611 2.6 2d1y:A, 2d1y:B, 2d1y:C, 2d1y:D, 8pa2:A, 8pa2:B, 8pa2:C, 8pa2:D, 7xqm:A, 7xqm:C, 7xqm:D
17 8w7m:5 529 26 0.0640 0.0208 0.4231 4.2
18 8b9a:5 533 26 0.0640 0.0206 0.4231 4.2 8b9b:5, 8b9c:5, 6sko:5
19 7pmn:5 660 26 0.0640 0.0167 0.4231 4.3
20 4jev:B 402 41 0.0756 0.0323 0.3171 5.2 4jev:A, 4jew:A, 4jew:B, 4jex:A, 4jex:B, 4jey:A, 4jey:B, 4jez:A, 4jez:B, 4jf1:A, 4jf1:B, 2pb0:A, 2pb0:B, 2pb2:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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