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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SYLPGYVPKTSLSSPPWPEVVLPDPVEETRHHAEVVKKVNEMIVTGQYGRLFAVVHFASRQWKVTSEDLILIGNELDLAC
GERIRLEKVLLVGADNFTLLGKPLLGKDLVRVEATVIEKTESWPRIIMRFRKRKNFKKKRIVTTPQTVLRINSIEIAPCL

The query sequence (length=160) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8any:S 161 160 1.0000 0.9938 1.0000 2.36e-116 7a5f:S3, 7a5g:S3, 7a5h:S, 7a5i:S3, 7a5j:S, 7a5k:S3, 6i9r:S, 3j7y:S, 3j9m:S, 8k2a:LU, 8k2b:LU, 7l08:S, 7l20:S, 6nu2:S, 6nu3:S, 7o9k:S, 7o9m:S, 7odr:S, 7ods:S, 7odt:S, 7of0:S, 7of2:S, 7of3:S, 7of4:S, 7of5:S, 7of6:S, 7of7:S, 7og4:XS, 7oi6:S, 7oi7:S, 7oi8:S, 7oi9:S, 7oia:S, 7oib:S, 7oic:S, 7oid:S, 7oie:S, 8oir:BZ, 8oit:BZ, 5ool:S, 5oom:S, 7pd3:S, 8pk0:S, 7po4:S, 7qh6:S, 7qh7:S, 7qi4:S, 7qi5:S, 7qi6:S, 8qsj:S, 8qu1:S, 8qu5:S, 6vlz:S, 6vmi:S, 8xt0:LU, 8xt1:LU, 8xt2:LU, 8xt3:LU, 6zm5:S, 6zm6:S, 6zs9:XS, 6zsa:XS, 6zsb:XS, 6zsc:XS, 6zsd:XS, 6zse:XS, 6zsg:XS
2 5aj4:BV 155 154 0.8063 0.8323 0.8377 6.35e-95 4ce4:V, 6gaw:BV, 6gb2:BV, 7nqh:BV, 7nql:BV, 7nsh:BV, 7nsi:BV, 7nsj:BV, 8oin:BZ, 8oiq:BZ, 4v19:V, 6ydp:BV, 6ydw:BV
3 6z1p:Av 206 107 0.2125 0.1650 0.3178 5.43e-10
4 7pkt:p 204 72 0.1625 0.1275 0.3611 9.60e-09
5 7aih:L 178 71 0.1938 0.1742 0.4366 4.86e-08 7am2:L, 7ane:L
6 6hiv:AV 181 112 0.2437 0.2155 0.3482 4.98e-08 7aoi:AV, 6hix:AV, 6yxx:AV, 6yxy:AV
7 8a22:Ap 200 56 0.1250 0.1000 0.3571 4.37e-06 8apn:Ap, 8apo:Ap
8 6spd:R 103 105 0.1875 0.2913 0.2857 1.00e-05 8cd1:R, 6spb:R, 6spf:R, 6spg:R, 7unr:T, 7unu:T, 7unv:T, 7unw:T
9 8buu:R 102 108 0.2000 0.3137 0.2963 1.33e-05 7aqc:g, 7aqd:g, 7as8:V, 7as9:V, 6ha1:R, 6ha8:R, 6htq:R, 3j3v:R, 3j3w:R, 3j9w:BU, 5njt:k, 7o5b:o, 7ope:V, 6ppf:R, 6ppk:R, 6pvk:R, 8qcq:R, 7qgu:R, 7qh4:R, 8qpp:o, 7qv1:R, 7qv2:R, 7qv3:R, 8r55:o, 8s1p:R, 8s1u:R, 7s9u:R, 7sae:R, 6tnn:k, 6tpq:k
10 8a57:U 101 108 0.1875 0.2970 0.2778 2.38e-05 8a5i:U, 8a63:U, 7nhn:U, 8uu4:T, 8uu5:T, 8uu6:T, 8uu7:T, 8uu8:T, 8uu9:T, 8uua:T
11 8a3l:q 103 90 0.1313 0.2039 0.2333 3.26e-05 7abz:R, 7ac7:R, 7acj:R, 7acr:R, 5ady:R, 5afi:R, 5aka:R, 8akn:q, 8am9:q, 8ana:q, 8ap4:q, 9ax7:q, 9ax8:R, 8aye:q, 8b0x:q, 7b5k:R, 8b7y:Z, 3bbx:R, 8bf7:O, 8bge:O, 8bgh:O, 8bh4:O, 8bhj:O, 8bhl:O, 8bhn:O, 8bhp:O, 8bil:O, 8bim:O, 7bl2:R, 7bl3:R, 7bl4:R, 7bl5:R, 7bl6:R, 6bu8:20, 7bv8:S, 6by1:CR, 6by1:DR, 6c4i:S, 8c8x:R, 8c8y:R, 8c8z:R, 8c90:R, 8c91:R, 8c92:R, 8c93:R, 8c94:R, 8c95:R, 8c96:R, 8c98:R, 8c99:R, 8cam:q, 8ceu:q, 8cgd:q, 8cgk:q, 8cgv:q, 9cg5:q, 9cg6:q, 9cg7:q, 9cl9:R, 7cpj:R, 4csu:R, 7d6z:R, 7d80:q, 6dnc:V, 8eiu:q, 8ekc:T, 8emm:q, 6enf:R, 6enj:R, 6enu:R, 9fbv:q, 8fiz:BY, 8fto:q, 8fzd:T, 8fze:T, 8fzf:T, 8fzg:T, 8fzh:T, 8fzi:T, 8fzj:T, 8g2u:R, 8g31:R, 8g34:R, 8g38:R, 8g6w:q, 8g6x:q, 8g6y:q, 8g7p:T, 8g7q:T, 8g7r:T, 8g7s:T, 5gad:S, 5gae:S, 5gaf:S, 5gag:S, 5gah:S, 6gbz:R, 6gc0:R, 6gc4:R, 6gc6:R, 6gc7:R, 6gc8:R, 6gwt:R, 6gxm:R, 6gxn:R, 6gxo:R, 6gxp:R, 6h4n:R, 5h5u:S, 6h58:R, 6h58:RR, 6hrm:R, 8hsp:q, 8htz:q, 8hu1:q, 6i0y:R, 6i7v:DS, 6i7v:CS, 8ifb:q, 8ifc:q, 5iqr:R, 5it8:CS, 5it8:DS, 8j1z:q, 2j28:R, 3j5l:R, 5j5b:CS, 5j5b:DS, 3j7z:R, 5j7l:CS, 5j7l:DS, 3j8g:R, 5j88:CS, 5j88:DS, 5j8a:CS, 5j8a:DS, 3j9y:R, 3j9z:LP, 5j91:CS, 5j91:DS, 3ja1:LT, 3jbu:r, 3jbv:r, 3jcd:R, 3jce:R, 3jcj:Q, 3jcn:R, 5jc9:CS, 5jc9:DS, 7jss:r, 7jsw:r, 7jsz:r, 5jte:BR, 7jt1:r, 7jt2:r, 7jt3:r, 5ju8:BR, 7k00:q, 7k50:r, 7k51:r, 7k52:r, 7k53:r, 7k54:r, 7k55:r, 5kcr:1V, 5kcs:1V, 5kps:R, 5kpv:Q, 5kpw:Q, 5kpx:Q, 5l3p:V, 6lkq:9, 7lv0:r, 7lvk:Z, 5lza:R, 5lzb:R, 5lzc:R, 5lzd:R, 5lze:R, 5lzf:R, 7m5d:R, 5mdv:R, 5mdw:R, 5mdy:R, 5mdz:R, 5mgp:R, 7n1p:LU, 7n2c:LU, 7n2u:LU, 7n2v:LU, 7n30:LU, 7n31:LU, 7nbu:q, 5nco:S, 5np6:p, 7nso:R, 7nsp:R, 7nsq:R, 5nwy:e, 7nwt:R, 7nww:Q, 7o19:BR, 7o1a:BR, 7o1c:BR, 5o2r:R, 6o9j:R, 6o9k:R, 7ode:Z, 6ofx:r, 6og7:r, 6ogf:r, 6ogg:r, 6ogi:r, 7oif:Q, 7oig:Q, 7oii:Q, 7oiz:q, 7oj0:q, 6om6:R, 6ore:R, 6orl:R, 6osk:R, 6osq:R, 6ost:R, 6ot3:R, 7ot5:Q, 7otc:R, 6ouo:R, 8p16:R, 8p17:R, 8p18:R, 7p3k:q, 8peg:u, 8phj:q, 6pj6:Z, 7pjs:R, 7pjt:R, 7pju:R, 7pjv:R, 7pjw:R, 7pjx:R, 7pjy:R, 7pjz:R, 8pkl:u, 8pva:q, 7q4k:BR, 8q4f:q, 6q97:R, 6q98:R, 6q9a:R, 8qbt:R, 6qdw:r, 7qg8:e, 7qgh:e, 7qgn:e, 7qgr:e, 8qk7:R, 8qoa:q, 7qq3:Z, 6qul:S, 8r6c:q, 8r8m:q, 8rpy:R, 8rpz:R, 8rq0:R, 8rq2:R, 6s0k:S, 7s1g:Z, 7s1h:Z, 7s1i:Z, 7s1j:Z, 7s1k:Z, 7sa4:R, 7ss9:r, 7ssd:r, 7ssl:r, 7ssn:r, 7sso:r, 7ssw:r, 7st2:r, 7st6:r, 7st7:r, 8syl:T, 6szs:R, 8t5d:R, 8t5h:R, 6tbv:L211, 6tc3:L211, 7tos:L21, 4u1u:BR, 4u1u:DR, 4u1v:BR, 4u1v:DR, 4u20:BR, 4u20:DR, 4u24:BR, 4u24:DR, 4u25:BR, 4u25:DR, 4u26:BR, 4u26:DR, 4u27:BR, 4u27:DR, 5u4i:S, 6u48:CS, 5u9f:20, 5u9g:20, 7ug7:LU, 7uph:q, 8upo:0, 8upr:0, 8uql:0, 8uqm:0, 8uqp:0, 8ur0:0, 8urh:0, 8uri:0, 8urx:0, 8ury:0, 4uy8:R, 5uyk:20, 5uyl:20, 5uym:20, 5uyn:20, 5uyp:20, 5uyq:20, 4v4h:BR, 4v4h:DR, 4v4q:BR, 4v4q:DR, 4v50:BR, 4v50:DR, 4v52:BR, 4v52:DR, 4v53:BR, 4v53:DR, 4v54:BR, 4v54:DR, 4v55:BR, 4v55:DR, 4v56:BR, 4v56:DR, 4v57:BR, 4v57:DR, 4v5b:AR, 4v5b:CR, 4v5h:BR, 4v5y:BR, 4v5y:DR, 4v64:BR, 4v64:DR, 4v65:BK, 4v66:BK, 4v69:BR, 4v6c:BR, 4v6c:DR, 4v6d:BR, 4v6d:DR, 4v6e:BR, 4v6e:DR, 4v6k:AS, 4v6l:BS, 4v6m:BR, 4v6n:AT, 4v6o:BT, 4v6p:BT, 4v6q:BT, 4v6r:BT, 4v6s:AT, 4v6t:BR, 4v6v:BV, 4v6y:BR, 4v6z:BR, 4v70:BR, 4v71:BR, 4v72:BR, 4v73:BR, 4v74:BR, 4v75:BR, 4v76:BR, 4v77:BR, 4v78:BR, 4v79:BR, 4v7a:BR, 4v7b:BR, 4v7c:BT, 4v7d:AU, 4v7i:AR, 4v7s:BR, 4v7s:DR, 4v7t:BR, 4v7t:DR, 4v7u:BR, 4v7u:DR, 4v7v:BR, 4v7v:DR, 4v85:BV, 4v89:BV, 4v9c:BR, 4v9c:DR, 4v9d:CR, 4v9d:DR, 4v9o:AR, 4v9o:CR, 4v9o:ER, 4v9o:GR, 4v9p:AR, 4v9p:CR, 4v9p:ER, 4v9p:GR, 8vs9:L21, 8vsa:L21, 6vu3:0, 6vwl:P, 6vwm:P, 6vwn:P, 6vyq:0, 6vyr:0, 6vys:0, 6vyt:0, 6vyu:0, 6vyw:0, 6vyx:0, 6vyy:0, 6vyz:0, 6vz2:0, 6vz3:0, 6vz5:0, 6vz7:0, 6vzj:0, 8w51:S, 5wdt:R, 6wd0:r, 6wd1:r, 6wd2:r, 6wd3:r, 6wd4:r, 6wd5:r, 6wd6:r, 6wd7:r, 6wd8:r, 6wd9:r, 6wda:r, 6wdb:r, 6wdc:r, 6wdd:r, 6wde:r, 6wdf:r, 6wdg:r, 6wdh:r, 6wdi:r, 6wdj:r, 6wdk:r, 6wdl:r, 6wdm:r, 5we4:R, 5we6:R, 4wf1:BR, 4wf1:DR, 5wf0:R, 5wfk:R, 5wfs:R, 6wnt:r, 6wnv:r, 6wnw:r, 4woi:BR, 4woi:CR, 4www:RR, 4www:YR, 6x6t:0, 6x7f:0, 6x7k:0, 6x9q:0, 6xdq:0, 6xdr:0, 6xgf:0, 6xii:0, 6xij:0, 6xz7:R, 6xza:R2, 6xzb:R2, 6y69:R, 7y7c:q, 7y7d:q, 7y7e:q, 7y7f:q, 7y7g:q, 7y7h:q, 4ybb:CS, 4ybb:DS, 7yla:Z, 6ys3:r, 6ysr:R, 6yss:R, 6yst:R, 6ysu:R, 7z20:r, 7zod:r, 7zp8:r, 7zq5:r, 7zq6:r, 6ztj:BS, 6ztl:BS, 6ztm:BS, 6ztn:BS, 6zto:BS, 6ztp:BS, 7zta:L211, 6zu1:BS
12 6xyw:Ar 137 58 0.1250 0.1460 0.3448 7.20e-05
13 6ywe:N 133 126 0.2313 0.2782 0.2937 8.18e-05 6yws:N, 6ywv:N, 6ywx:N, 6ywy:N
14 5zeb:S 102 105 0.1875 0.2941 0.2857 1.67e-04 6dzi:S, 6dzp:S, 8fr8:X, 8kab:S, 5o60:S, 5o61:S, 7s0s:T, 8v9j:T, 8v9k:T, 8v9l:T, 8whx:U, 8why:U, 8wi7:U, 8wi8:U, 8wib:U, 8wic:U, 7xam:S, 5xym:R, 8xz3:S, 7y41:S, 5zep:S, 5zet:S
15 6o8w:S 102 104 0.1562 0.2451 0.2404 3.42e-04 7nhk:U, 6o8x:S, 6o8y:S, 6o8z:S, 6o90:S, 7p7q:U, 7p7r:U, 7p7s:U, 7p7t:U, 7p7u:U, 6w6p:S, 6wu9:S
16 8rd8:Qb 103 104 0.1750 0.2718 0.2692 0.002 8rdv:Qb, 8rdw:Qb
17 1sm1:P 100 107 0.1437 0.2300 0.2150 0.015 7a0r:O, 7a0s:O, 7a18:O, 3cf5:O, 3dll:O, 5dm6:O, 5dm7:O, 4io9:O, 4ioa:O, 4ioc:O, 5jvg:O, 5jvh:O, 3pio:O, 3pip:O, 4u67:O, 4v4g:BS, 4v4g:DS, 4v4g:FS, 4v4g:HS, 4v4g:JS, 4v4p:A2, 4v4r:BV, 4v4s:BV, 4v4t:BV, 4wfn:O, 1xbp:P, 2zjp:O, 2zjq:O, 2zjr:O
18 5mmi:S 170 55 0.1250 0.1176 0.3636 0.037 6eri:AR, 5h1s:T, 5mlc:T, 5mmm:S, 4v61:BT, 5x8p:S, 5x8t:S
19 8fmw:AT 103 89 0.1313 0.2039 0.2360 0.15 8fn2:T
20 7jil:R 104 84 0.1562 0.2404 0.2976 0.24
21 7we4:A 1122 76 0.1375 0.0196 0.2895 0.43 7wel:A, 7wfr:A, 7wfw:A
22 7asm:P 102 104 0.1938 0.3039 0.2981 0.43 7asn:P, 7aso:U, 7asp:P, 6ddd:D, 6ddg:D, 6fxc:AP, 6fxc:BP, 5hkv:O, 5hl7:O, 6hma:P, 5li0:U, 5nd8:U, 5nd9:U, 5ngm:AP, 7nhl:U, 7nhm:U, 5nrg:O, 8p2f:U, 8p2g:U, 8p2h:U, 7p48:P, 6s0x:P, 6s0z:P, 6s12:P, 6s13:P, 6sj6:U, 5t7v:L4, 5tcu:L4, 7ttu:D, 7ttw:D, 4wce:O, 4wf9:O, 4wfa:O, 4wfb:O, 6wqn:D, 6wqq:D, 6wrs:D, 6wru:D, 8y36:P, 8y37:P, 8y38:P, 8y39:P, 6yef:U
23 2hye:B 180 112 0.2062 0.1833 0.2946 2.8 2b5l:C, 2b5l:D, 4i1s:B
24 5h7w:B 529 48 0.1125 0.0340 0.3750 4.1 7d0v:A, 7d0v:B, 5h7w:A
25 6af6:A 383 18 0.0563 0.0235 0.5000 5.8 5zw2:A, 5zw7:A, 5zw8:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218